Evaluación de métodos para la inoculación y diagnóstico del virus del mosaico del pepino (CMV)
El virus del mosaico del pepino (CMV) es un agente limitante en la producción y calidad de cultivos agrícolas cuya inoculación efectiva y diagnóstico confiable son esenciales para implementar estrategias de manejo adecuadas y oportunas. Se evaluaron dos protocolos para la inoculación del CMV en plan...
- Autores:
-
Villegas-Estrada, Bernardo
Valencia, Arnubio
Sánchez, Manuel Alejandro
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2020
- Institución:
- UNIVERSIDAD FRANCISCO DE PAULA SANTANDER
- Repositorio:
- Repositorio Digital UFPS
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.ufps.edu.co:ufps/625
- Acceso en línea:
- http://repositorio.ufps.edu.co/handle/ufps/625
- Palabra clave:
- ImmunoStrip
Enfermedad
Serología
ImmunoStrip
Disease
Serology
ImmunoStrip
Doença
Serologia
- Rights
- openAccess
- License
- Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)
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Evaluación de métodos para la inoculación y diagnóstico del virus del mosaico del pepino (CMV) |
| dc.title.eng.fl_str_mv |
Evaluation of methods for inoculation and diagnosis of the cucumber mosaic virus (CMV) |
| dc.title.por.fl_str_mv |
Avaliação de métodos para inoculação e diagnóstico de vírus de mosaico do pepino (CMV) |
| title |
Evaluación de métodos para la inoculación y diagnóstico del virus del mosaico del pepino (CMV) |
| spellingShingle |
Evaluación de métodos para la inoculación y diagnóstico del virus del mosaico del pepino (CMV) ImmunoStrip Enfermedad Serología ImmunoStrip Disease Serology ImmunoStrip Doença Serologia |
| title_short |
Evaluación de métodos para la inoculación y diagnóstico del virus del mosaico del pepino (CMV) |
| title_full |
Evaluación de métodos para la inoculación y diagnóstico del virus del mosaico del pepino (CMV) |
| title_fullStr |
Evaluación de métodos para la inoculación y diagnóstico del virus del mosaico del pepino (CMV) |
| title_full_unstemmed |
Evaluación de métodos para la inoculación y diagnóstico del virus del mosaico del pepino (CMV) |
| title_sort |
Evaluación de métodos para la inoculación y diagnóstico del virus del mosaico del pepino (CMV) |
| dc.creator.fl_str_mv |
Villegas-Estrada, Bernardo Valencia, Arnubio Sánchez, Manuel Alejandro |
| dc.contributor.author.none.fl_str_mv |
Villegas-Estrada, Bernardo Valencia, Arnubio Sánchez, Manuel Alejandro |
| dc.subject.proposal.spa.fl_str_mv |
ImmunoStrip Enfermedad Serología |
| topic |
ImmunoStrip Enfermedad Serología ImmunoStrip Disease Serology ImmunoStrip Doença Serologia |
| dc.subject.proposal.eng.fl_str_mv |
ImmunoStrip Disease Serology |
| dc.subject.proposal.por.fl_str_mv |
ImmunoStrip Doença Serologia |
| description |
El virus del mosaico del pepino (CMV) es un agente limitante en la producción y calidad de cultivos agrícolas cuya inoculación efectiva y diagnóstico confiable son esenciales para implementar estrategias de manejo adecuadas y oportunas. Se evaluaron dos protocolos para la inoculación del CMV en plantas indicadoras (Nicotiana benthamiana y N. tabacum cv. Xanthi) y diferentes métodos de detección de este virus. La infección de plantas con CMV se logró mediante transmisión mecánica e infiltración. La presencia del virus se confirmó mediante la expresión de síntomas, serología (ImmunoStrip®), RT-PCR y por secuenciación. Los resultados confirmaron la efectividad del método de transmisión mecánica, en el cual, las plantas infectadas presentaron sintomatología asociada con el virus 15 días después de su inoculación. La prueba serológica permitió detectar la presencia del patógeno solo en las plantas de N. benthamiana, mientras que la prueba de RT-PCR en todas las plantas evaluadas. Los resultados de secuenciación mostraron altos valores de identidad nucleotídica con las secuencias reportadas en el NCBI para este virus. La transmisión mecánica fue el método más efectivo para la inoculación del CMV y las técnicas de análisis molecular fueron más sensibles y confiables para su identificación, en comparación con la prueba serológica. |
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2020 |
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2020-07-01 |
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2021-11-03T21:38:26Z |
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2021-11-03T21:38:26Z |
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10.18684/BSAA(19)92-104 |
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Biotecnología En El Sector Agropecuario Y Agroindustrial ISSN: 1909-9959, 2021 vol:19 fasc: 1 págs: 92 - 104, DOI:10.18684/BSAA(19)92-104 |
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SÁNCHEZ, MANUEL-ALEJANDRO; VILLEGAS-ESTRADA, BERNARDO; VALENCIA-JIMÉNEZ, ARNUBIO. Evaluación de métodos para la inoculación y diagnóstico del virus del mosaico del pepino (CMV). Biotecnología en el sector agropecuario y agroindustrial, v. 19, n. 1, 2021, p. 92-104. Doi: https://doi. org/10.18684/BSAA(19)92-104 |
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Biotecnología En El Sector Agropecuario Y Agroindustrial |
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Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0) |
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openAccess |
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Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0) http://purl.org/coar/access_right/c_abf2 |
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Biotecnología En El Sector Agropecuario Y Agroindustrial |
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Villegas-Estrada, Bernardo3e94762a519969315cf06404fd5a07cb600Valencia, Arnubioacccae6988653f7bf6a00d4e86854c1b600Sánchez, Manuel Alejandro5c8897da1223ede8de480ac08e6ece742021-11-03T21:38:26Z2021-11-03T21:38:26Z2020-07-01http://repositorio.ufps.edu.co/handle/ufps/62510.18684/BSAA(19)92-104El virus del mosaico del pepino (CMV) es un agente limitante en la producción y calidad de cultivos agrícolas cuya inoculación efectiva y diagnóstico confiable son esenciales para implementar estrategias de manejo adecuadas y oportunas. Se evaluaron dos protocolos para la inoculación del CMV en plantas indicadoras (Nicotiana benthamiana y N. tabacum cv. Xanthi) y diferentes métodos de detección de este virus. La infección de plantas con CMV se logró mediante transmisión mecánica e infiltración. La presencia del virus se confirmó mediante la expresión de síntomas, serología (ImmunoStrip®), RT-PCR y por secuenciación. Los resultados confirmaron la efectividad del método de transmisión mecánica, en el cual, las plantas infectadas presentaron sintomatología asociada con el virus 15 días después de su inoculación. La prueba serológica permitió detectar la presencia del patógeno solo en las plantas de N. benthamiana, mientras que la prueba de RT-PCR en todas las plantas evaluadas. Los resultados de secuenciación mostraron altos valores de identidad nucleotídica con las secuencias reportadas en el NCBI para este virus. La transmisión mecánica fue el método más efectivo para la inoculación del CMV y las técnicas de análisis molecular fueron más sensibles y confiables para su identificación, en comparación con la prueba serológica.O vírus do mosaico do pepino (CMV) é um agente limitante na produção e qualidade das culturas agrícolas cuja inoculação eficaz e diagnóstico confiável são essenciais para implementar estratégias de manejo adequadas e oportunas. Foram avaliados dois protocolos de inoculação de CMV em plântulas indicadoras (Nicotiana benthamiana e N. tabacum cv. Xanthi) e diferentes métodos de detecção do vírus. A infecção com CMV foi obtida por transmissão mecânica e por infiltração. A presença do vírus foi confirmada pela expressão dos sintomas, serologia (ImmunoStrip®), RT-PCR e sequenciamento. Os resultados confirmaram a eficácia da transmissão mecânica, no qual plântulas infectadas apresentaram sintomas associados ao vírus 15 dias após a inoculação. O teste serológico permitiu detectar a presença do patógeno apenas nas plantas de N. benthamiana, enquanto o teste RT-PCR em todas as plantulas avaliadas. Os resultados do sequenciamento mostraram altos valores de identidade de nucleotídeos com as sequências do vírus no NCBI. A transmissão mecânica foi o método mais eficaz para a inoculação do CMV e as técnicas de análise molecular foram mais sensíveis e confiáveis para identificação do CMV, em comparação com os testes serológicos.The cucumber mosaic virus (CMV) is a limiting agent in the production and quality of agricultural crops whose effective inoculation and reliable diagnosis are essential to implement suitable and timely management strategies. Two protocols for CMV inoculation (Nicotiana benthamiana and N. tabacum cv. Xanthi) as indicator plants and different virus detection methods were evaluated. Infection of plants with CMV was achieved by mechanical transmission and infiltration. The presence of the virus was confirmed by expression of symptoms, serology (ImmunoStrip®), RT-PCR and by sequencing. The results confirmed the effectiveness of the mechanical transmission. The infected plants showed symptoms associated with the pathogen 15 days after inoculation. The serological test allowed detecting the presence of the pathogen only in N. benthamiana plants, while the RT-PCR test in all evaluated plants. The sequencing results showed high nucleotide identity values with the sequences reported in the NBCI for this virus. Mechanical transmission was the most effective method for CMV inoculation, and molecular analysis techniques were more sensitive and reliable for CMV identification, compared to serological test.13 páginasapplication/pdfspaBiotecnología En El Sector Agropecuario Y AgroindustrialBiotecnología En El Sector Agropecuario Y Agroindustrial ISSN: 1909-9959, 2021 vol:19 fasc: 1 págs: 92 - 104, DOI:10.18684/BSAA(19)92-104Vol. 19, No. 1 (2021)1041 (2021)9219SÁNCHEZ, MANUEL-ALEJANDRO; VILLEGAS-ESTRADA, BERNARDO; VALENCIA-JIMÉNEZ, ARNUBIO. Evaluación de métodos para la inoculación y diagnóstico del virus del mosaico del pepino (CMV). Biotecnología en el sector agropecuario y agroindustrial, v. 19, n. 1, 2021, p. 92-104. Doi: https://doi. org/10.18684/BSAA(19)92-104Biotecnología En El Sector Agropecuario Y AgroindustrialEsta obra está bajo licencia internacional Creative Commons Reconocimiento-NoComercial-SinObrasDerivadas 4.0. Los autores que publican en la revista se acogen al código de licencia creative commons 4.0 de atribución, no comercial, sin derivadosinfo:eu-repo/semantics/openAccessAtribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)http://purl.org/coar/access_right/c_abf2https://revistas.unicauca.edu.co/index.php/biotecnologia/article/view/1564Evaluación de métodos para la inoculación y diagnóstico del virus del mosaico del pepino (CMV)Evaluation of methods for inoculation and diagnosis of the cucumber mosaic virus (CMV)Avaliação de métodos para inoculação e diagnóstico de vírus de mosaico do pepino (CMV)Artículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85ImmunoStripEnfermedadSerologíaImmunoStripDiseaseSerologyImmunoStripDoençaSerologiaZHAO, LEI; FENG, CHAOHONG; WU, KUAN; CHEN, WENBAO; CHEN, YUJIA; HAO, XINGAN; WU, YUNFENGAdvances and prospects in biogenic substances against plant virus: A review. Pesticide biochemistry and physiology, v. 135, 2017, p. 15-26. https://doi.org/10.1016/j.pestbp.2016.07.003GAUR, RAJARSHI-KUMAR; KHURANA, PAUL; DOROKHOV, YURI (Eds.). Plant Viruses: Diversity, Interaction and Management. Boca Raton-FL (USA): CRC Press, 2018, 387 p.HAMMOND, ROSEMARIE. Economic significance of viroids in vegetable and field crops. En: Viroids and satellites. London (UK): Academic Press: 2017, p. 5-13. https://doi.org/10.1016/B978-0-12-801498-1.00001-2SCHOLTHOF, KAREN-BETH; ADKINS, SCOTT; CZOSNEK, HENRYK; PALUKAITIS, PETER; JACQUOT, AMMANUEL; HOHN, THOMAS; HOHN, BARBARA; SAUNDERS, KEITH; CANDRESSE, THIERRY; AHLQUIST, PAUL; HEMENWAY, CYNTHIA; FOSTER, GARY. Top 10 plant viruses in molecular plant pathology. Molecular Plant Pathology, v, 12, n. 9, 2011, p. 938-954. https://doi.org/10.1111/j.1364-3703.2011.00752.xVIVEROS-FOLLECO, YOHANA-MARITZA; GUZMÁN-PIEDRAHITA, ÓSCAR-ADRIÁN; VILLEGAS-ESTRADA, BERNARDO. Enfermedades en viveros comerciales de Musa AAB ‘Dominico hartón’ en el departamento de Caldas, Colombia. Boletín científico centro de museos museo de Historia Natural, v. 21, n. 2, 2017, p, 61-80. http://dx.doi.org/10.17151/bccm.2017.21.2.5RODRÍGUEZ, MARLON H.; NIÑO, NANCY E.; CUTLER, JOSEPH; LANGER, JULIANE; CASIERRA-POSADA, FÁNOR; MIRANDA, DIEGO; BANDTE, MARTINA; BÜTTNER, CARMEN. Certificación de material vegetal sano en Colombia: un análisis crítico de oportunidades y retos para controlar enfermedades ocasionadas por virus. Revista Colombiana de Ciencias Hortícolas, v. 10, n. 1, 2016, p. 164-175. http://dx.doi.org/10.17584/rcch.2016v10i1.4921GALLO, YULIANA; TORO, LUISA-FERNANDA; JARAMILLO, HELENA; GUTIÉRREZ, PABLO-ANDRÉS. Identificación y caracterización molecular del genoma completo de tres virus en cultivos de lulo (Solanum quitoense) de Antioquia (Colombia). Revista Colombiana de Ciencias Hortícolas, v. 12, n. 2, 2018 p. 281-292. http://doi.org/10.17584/rcch.2018v12i2.7692PALUKAITIS, PETER; GARCIA-ARENAL, FERNANDO. Cucumoviruses. Advances in Virus Research, v. 62, 2003, p. 241–323. https://doi.org/10.1016/s0065-3527(03)62005-1AEBIG, JOAN A.; KAMO, KATHRYN; HSU, HEI-TI. Biolistic inoculation of gladiolus with Cucumber Mosaic Cucumovirus. Journal of virological methods, v. 123, n. 1, 2005, p. 89-94. https://doi.org/10.1016/j.jviromet.2004.09.010RAJAMANICKAM, S.; KUMAR, RAJESH; KARTHIKEYAN, G. A potential tool for the detection of plant viruses through serological and molecular approaches. Journal of Pharmacognosy and Phytochemistry, v. 8, n. 3, 2019, p. 3046-3051.HONG, JIN-SUNG; JU, HO-JONG. The plant cellular systems for plant virus movement. The plant pathology journal, v. 33, n. 3, 2017, p. 213-228. https://doi.org/10.5423/PPJ.RW.09.2016.0198MOCHIZUKI, TOMOFUMO; OHKI, SATOSHI. Cucumber mosaic virus: viral genes as virulence determinants. Molecular plant pathology, v. 13, n. 3, 2012, p. 217-225. https://doi.org/10.1111/j.1364-3703.2011.00749.xNOURI, SHAHIDEH; ARÉVALO, RAFAEL; FALK, BRYCE; GROVES, RUSSELL. Genetic structure and molecular variability of Cucumber Mosaic Virus isolates in the United States. PLoS One, v. 9, n. 5, 2014, p. e96582. 10.1371/journal.pone.0096582QIU, Y.; WANG, C.; ZHU, S. A Review on the Pathogenicity of Cucumber Mosaic Virus. Agricultural Biotechnology, v. 7, n. 1, 2018, p. 87-91.GONZÁLEZ-GARZA, RAMIRO. Evolution of diagnostic technics for plant viruses. Revista Mexicana de Fitopatología, v. 35, n. 3, 2017, p. 591-610. https://doi.org/10.18781/R.MEX.FIT.1706-1VARMA, ANUPAM; SINGH, MANOJ-KUMAR. En: Applied Plant Virology: Advances, Detection, and Antiviral Strategies. Diagnosis of plant virus diseases. Cambridge (USA): Academic Press, 2020, p. 79-92. https://doi.org/10.1016/B978-0-12-818654-1.00006-2BALODI, REKHA; BISHT, SUNAINA; GHATAK, ABHIJEET. Plant disease diagnosis: Technological advancements and challenges. Indian Phytopathology, v. 70, n. 3, 2017, p. 275-281. 10.24838/ip.2017.v70.i3.72487KIRANKUMAR, K.C.; PRIYA, N.; JAYASUDHA, S.M.; BHAT, GOUREESH. En: Applied Plant Virology: Advances, Detection, and Antiviral Strategies. Advances in protein-based diagnostic tools of plant viruses. Cambridge (USA): Academic Press, 2020. p. 93-99. https://doi.org/10.1016/B978-0-12-818654-1.00007-4BUITRÓN-BUSTAMANTE, JOHANNA-LISETH; MORILLO-VELASTEGUI, EDUARDO. Estandarización de un método de detección molecular del Cucumber mosaic virus (CMV) en banano ecuatoriano. Ciencia y Tecnología Agropecuaria, v. 18, n. 1, 2017, p. 113-124. http://dx.doi.org/10.21930/rcta.vol18_num1_art:562HAJIA, MASOUD. Limitations of different PCR protocols used in diagnostic laboratories: a short review. Modern Medical Laboratory Journal, v. 1, n. 1, 2017, p. 1-6.YADAV, KAVITA; YADAV, PRABHAT. 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texttext/plain41453https://repositorio.ufps.edu.co/bitstream/ufps/625/3/Evaluaci%c3%b3n%20de%20m%c3%a9todos%20para%20la%20inoculaci%c3%b3n%20y%20diagn%c3%b3stico%20del%20virus%20del%20mosaico%20del%20pepino%20%28CMV%29.pdf.txt8b32b7a48e2a338f4892c4cf45321afeMD53open accessTHUMBNAILEvaluación de métodos para la inoculación y diagnóstico del virus del mosaico del pepino (CMV).pdf.jpgEvaluación de métodos para la inoculación y diagnóstico del virus del mosaico del pepino (CMV).pdf.jpgGenerated Thumbnailimage/jpeg11379https://repositorio.ufps.edu.co/bitstream/ufps/625/4/Evaluaci%c3%b3n%20de%20m%c3%a9todos%20para%20la%20inoculaci%c3%b3n%20y%20diagn%c3%b3stico%20del%20virus%20del%20mosaico%20del%20pepino%20%28CMV%29.pdf.jpgf084faede8bdd264d66e39659923d26aMD54open accessufps/625oai:repositorio.ufps.edu.co:ufps/6252022-05-23 10:42:44.138open accessRepositorio Universidad Francisco de Paula 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 incorporada en las Obras Colectivas.

b.	Distribuir copias o fonogramas de las Obras, exhibirlas públicamente, ejecutarlas públicamente y/o ponerlas a disposición pública, incluyéndolas como incorporadas en Obras Colectivas, según corresponda.

c.	Distribuir copias de las Obras Derivadas que se generen, exhibirlas públicamente, ejecutarlas públicamente y/o ponerlas a disposición pública.
Los derechos mencionados anteriormente pueden ser ejercidos en todos los medios y formatos, actualmente conocidos o que se inventen en el futuro. Los derechos antes mencionados incluyen el derecho a realizar dichas modificaciones en la medida que sean técnicamente necesarias para ejercer los derechos en otro medio o formatos, pero de otra manera usted no está autorizado para realizar obras derivadas. Todos los derechos no otorgados expresamente por el Licenciante quedan por este medio reservados, incluyendo pero sin limitarse a aquellos que se mencionan en las secciones 4(d) y 4(e).

4. Restricciones.
La licencia otorgada en la anterior Sección 3 está expresamente sujeta y limitada por las siguientes restricciones:

a.	Usted puede distribuir, exhibir públicamente, ejecutar públicamente, o poner a disposición pública la Obra sólo bajo las condiciones de esta Licencia, y Usted debe incluir una copia de esta licencia o del Identificador Universal de Recursos de la misma con cada copia de la Obra que distribuya, exhiba públicamente, ejecute públicamente o ponga a disposición pública. No es posible ofrecer o imponer ninguna condición sobre la Obra que altere o limite las condiciones de esta Licencia o el ejercicio de los derechos de los destinatarios otorgados en este documento. No es posible sublicenciar la Obra. Usted debe mantener intactos todos los avisos que hagan referencia a esta Licencia y a la cláusula de limitación de garantías. Usted no puede distribuir, exhibir públicamente, ejecutar públicamente, o poner a disposición pública la Obra con alguna medida tecnológica que controle el acceso o la utilización de ella de una forma que sea inconsistente con las condiciones de esta Licencia. Lo anterior se aplica a la Obra incorporada a una Obra Colectiva, pero esto no exige que la Obra Colectiva aparte de la obra misma quede sujeta a las condiciones de esta Licencia. Si Usted crea una Obra Colectiva, previo aviso de cualquier Licenciante debe, en la medida de lo posible, eliminar de la Obra Colectiva cualquier referencia a dicho Licenciante o al Autor Original, según lo solicitado por el Licenciante y conforme lo exige la cláusula 4(c).

b.	Usted no puede ejercer ninguno de los derechos que le han sido otorgados en la Sección 3 precedente de modo que estén principalmente destinados o directamente dirigidos a conseguir un provecho comercial o una compensación monetaria privada. El intercambio de la Obra por otras obras protegidas por derechos de autor, ya sea a través de un sistema para compartir archivos digitales (digital file-sharing) o de cualquier otra manera no será considerado como estar destinado principalmente o dirigido directamente a conseguir un provecho comercial o una compensación monetaria privada, siempre que no se realice un pago mediante una compensación monetaria en relación con el intercambio de obras protegidas por el derecho de autor.

c.	Si usted distribuye, exhibe públicamente, ejecuta públicamente o ejecuta públicamente en forma digital la Obra o cualquier Obra Derivada u Obra Colectiva, Usted debe mantener intacta toda la información de derecho de autor de la Obra y proporcionar, de forma razonable según el medio o manera que Usted esté utilizando: (i) el nombre del Autor Original si está provisto (o seudónimo, si fuere aplicable), y/o (ii) el nombre de la parte o las partes que el Autor Original y/o el Licenciante hubieren designado para la atribución (v.g., un instituto patrocinador, editorial, publicación) en la información de los derechos de autor del Licenciante, términos de servicios o de otras formas razonables; el título de la Obra si está provisto; en la medida de lo razonablemente factible y, si está provisto, el Identificador Uniforme de Recursos (Uniform Resource Identifier) que el Licenciante especifica para ser asociado con la Obra, salvo que tal URI no se refiera a la nota sobre los derechos de autor o a la información sobre el licenciamiento de la Obra; y en el caso de una Obra Derivada, atribuir el crédito identificando el uso de la Obra en la Obra Derivada (v.g., "Traducción Francesa de la Obra del Autor Original," o "Guión Cinematográfico basado en la Obra original del Autor Original"). Tal crédito puede ser implementado de cualquier forma razonable; en el caso, sin embargo, de Obras Derivadas u Obras Colectivas, tal crédito aparecerá, como mínimo, donde aparece el crédito de cualquier otro autor comparable y de una manera, al menos, tan destacada como el crédito de otro autor comparable.

d.	Para evitar toda confusión, el Licenciante aclara que, cuando la obra es una composición musical:

i.	Regalías por interpretación y ejecución bajo licencias generales. El Licenciante se reserva el derecho exclusivo de autorizar la ejecución pública o la ejecución pública digital de la obra y de recolectar, sea individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, SAYCO), las regalías por la ejecución pública o por la ejecución pública digital de la obra (por ejemplo Webcast) licenciada bajo licencias generales, si la interpretación o ejecución de la obra está primordialmente orientada por o dirigida a la obtención de una ventaja comercial o una compensación monetaria privada.

ii.	Regalías por Fonogramas. El Licenciante se reserva el derecho exclusivo de recolectar, individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, los consagrados por la SAYCO), una agencia de derechos musicales o algún agente designado, las regalías por cualquier fonograma que Usted cree a partir de la obra (“versión cover”) y distribuya, en los términos del régimen de derechos de autor, si la creación o distribución de esa versión cover está primordialmente destinada o dirigida a obtener una ventaja comercial o una compensación monetaria privada.

e.	Gestión de Derechos de Autor sobre Interpretaciones y Ejecuciones Digitales (WebCasting). Para evitar toda confusión, el Licenciante aclara que, cuando la obra sea un fonograma, el Licenciante se reserva el derecho exclusivo de autorizar la ejecución pública digital de la obra (por ejemplo, webcast) y de recolectar, individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, ACINPRO), las regalías por la ejecución pública digital de la obra (por ejemplo, webcast), sujeta a las disposiciones aplicables del régimen de Derecho de Autor, si esta ejecución pública digital está primordialmente dirigida a obtener una ventaja comercial o una compensación monetaria privada.

5. Representaciones, Garantías y Limitaciones de Responsabilidad.
A MENOS QUE LAS PARTES LO ACORDARAN DE OTRA FORMA POR ESCRITO, EL LICENCIANTE OFRECE LA OBRA (EN EL ESTADO EN EL QUE SE ENCUENTRA) “TAL CUAL”, SIN BRINDAR GARANTÍAS DE CLASE ALGUNA RESPECTO DE LA OBRA, YA SEA EXPRESA, IMPLÍCITA, LEGAL O CUALQUIERA OTRA, INCLUYENDO, SIN LIMITARSE A ELLAS, GARANTÍAS DE TITULARIDAD, COMERCIABILIDAD, ADAPTABILIDAD O ADECUACIÓN A PROPÓSITO DETERMINADO, AUSENCIA DE INFRACCIÓN, DE AUSENCIA DE DEFECTOS LATENTES O DE OTRO TIPO, O LA PRESENCIA O AUSENCIA DE ERRORES, SEAN O NO DESCUBRIBLES (PUEDAN O NO SER ESTOS DESCUBIERTOS). ALGUNAS JURISDICCIONES NO PERMITEN LA EXCLUSIÓN DE GARANTÍAS IMPLÍCITAS, EN CUYO CASO ESTA EXCLUSIÓN PUEDE NO APLICARSE A USTED.

6. Limitación de responsabilidad.
A MENOS QUE LO EXIJA EXPRESAMENTE LA LEY APLICABLE, EL LICENCIANTE NO SERÁ RESPONSABLE ANTE USTED POR DAÑO ALGUNO, SEA POR RESPONSABILIDAD EXTRACONTRACTUAL, PRECONTRACTUAL O CONTRACTUAL, OBJETIVA O SUBJETIVA, SE TRATE DE DAÑOS MORALES O PATRIMONIALES, DIRECTOS O INDIRECTOS, PREVISTOS O IMPREVISTOS PRODUCIDOS POR EL USO DE ESTA LICENCIA O DE LA OBRA, AUN CUANDO EL LICENCIANTE HAYA SIDO ADVERTIDO DE LA POSIBILIDAD DE DICHOS DAÑOS. ALGUNAS LEYES NO PERMITEN LA EXCLUSIÓN DE CIERTA RESPONSABILIDAD, EN CUYO CASO ESTA EXCLUSIÓN PUEDE NO APLICARSE A USTED.

7. Término.

a.	Esta Licencia y los derechos otorgados en virtud de ella terminarán automáticamente si Usted infringe alguna condición establecida en ella. Sin embargo, los individuos o entidades que han recibido Obras Derivadas o Colectivas de Usted de conformidad con esta Licencia, no verán terminadas sus licencias, siempre que estos individuos o entidades sigan cumpliendo íntegramente las condiciones de estas licencias. Las Secciones 1, 2, 5, 6, 7, y 8 subsistirán a cualquier terminación de esta Licencia.

b.	Sujeta a las condiciones y términos anteriores, la licencia otorgada aquí es perpetua (durante el período de vigencia de los derechos de autor de la obra). No obstante lo anterior, el Licenciante se reserva el derecho a publicar y/o estrenar la Obra bajo condiciones de licencia diferentes o a dejar de distribuirla en los términos de esta Licencia en cualquier momento; en el entendido, sin embargo, que esa elección no servirá para revocar esta licencia o que deba ser otorgada , bajo los términos de esta licencia), y esta licencia continuará en pleno vigor y efecto a menos que sea terminada como se expresa atrás. La Licencia revocada continuará siendo plenamente vigente y efectiva si no se le da término en las condiciones indicadas anteriormente.

8. Varios.

a.	Cada vez que Usted distribuya o ponga a disposición pública la Obra o una Obra Colectiva, el Licenciante ofrecerá al destinatario una licencia en los mismos términos y condiciones que la licencia otorgada a Usted bajo esta Licencia.

b.	Si alguna disposición de esta Licencia resulta invalidada o no exigible, según la legislación vigente, esto no afectará ni la validez ni la aplicabilidad del resto de condiciones de esta Licencia y, sin acción adicional por parte de los sujetos de este acuerdo, aquélla se entenderá reformada lo mínimo necesario para hacer que dicha disposición sea válida y exigible.

c.	Ningún término o disposición de esta Licencia se estimará renunciada y ninguna violación de ella será consentida a menos que esa renuncia o consentimiento sea otorgado por escrito y firmado por la parte que renuncie o consienta.

d.	Esta Licencia refleja el acuerdo pleno entre las partes respecto a la Obra aquí licenciada. No hay arreglos, acuerdos o declaraciones respecto a la Obra que no estén especificados en este documento. El Licenciante no se verá limitado por ninguna disposición adicional que pueda surgir en alguna comunicación emanada de Usted. Esta Licencia no puede ser modificada sin el consentimiento mutuo por escrito del Licenciante y Usted.
 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