Tuberculosis in the colombian-venezuelan border: geospatial distribution
The geospatial distribution of pulmonary and extrapulmonary tuberculosis (TB) morbidity in the municipality of Cucuta in 2019 and 2020 was described by the Kulldorff method using the geographic location and reporting date of incident TB cases. The unit of analysis was the event reported to the Natio...
- Autores:
-
Ruiz Roa, Silvia Liliana
Martinez Rojas, Sandra Milena
Serna Galeano, Ivan Andres
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2022
- Institución:
- Universidad Francisco de Paula Santander
- Repositorio:
- Repositorio Digital UFPS
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.ufps.edu.co:ufps/6992
- Acceso en línea:
- https://repositorio.ufps.edu.co/handle/ufps/6992
- Palabra clave:
- Geographic Information Systems
Spatial Analysis
Cluster Analysis
Geographic mapping
Tuberculosis
Morbidity
- Rights
- openAccess
- License
- This work is licensed under a Creative Commons Attribution 4.0 International License.
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Tuberculosis in the colombian-venezuelan border: geospatial distribution |
| title |
Tuberculosis in the colombian-venezuelan border: geospatial distribution |
| spellingShingle |
Tuberculosis in the colombian-venezuelan border: geospatial distribution Geographic Information Systems Spatial Analysis Cluster Analysis Geographic mapping Tuberculosis Morbidity |
| title_short |
Tuberculosis in the colombian-venezuelan border: geospatial distribution |
| title_full |
Tuberculosis in the colombian-venezuelan border: geospatial distribution |
| title_fullStr |
Tuberculosis in the colombian-venezuelan border: geospatial distribution |
| title_full_unstemmed |
Tuberculosis in the colombian-venezuelan border: geospatial distribution |
| title_sort |
Tuberculosis in the colombian-venezuelan border: geospatial distribution |
| dc.creator.fl_str_mv |
Ruiz Roa, Silvia Liliana Martinez Rojas, Sandra Milena Serna Galeano, Ivan Andres |
| dc.contributor.author.none.fl_str_mv |
Ruiz Roa, Silvia Liliana Martinez Rojas, Sandra Milena Serna Galeano, Ivan Andres |
| dc.subject.proposal.eng.fl_str_mv |
Geographic Information Systems Spatial Analysis Cluster Analysis Geographic mapping Tuberculosis Morbidity |
| topic |
Geographic Information Systems Spatial Analysis Cluster Analysis Geographic mapping Tuberculosis Morbidity |
| description |
The geospatial distribution of pulmonary and extrapulmonary tuberculosis (TB) morbidity in the municipality of Cucuta in 2019 and 2020 was described by the Kulldorff method using the geographic location and reporting date of incident TB cases. The unit of analysis was the event reported to the National Epidemiological Surveillance System (SIVIGILA). A total of 607 cases were identified in 392 neighborhoods distributed in ten communes. Most cases of pulmonary TB were reported in the northern commune, with the El Salado neighborhood being the most affected repeatedly. Incident cases of extrapulmonary TB did not show patterns of repetition in the distribution between spatial and temporal units. Strategies to mitigate and control the spread of pulmonary infection should prioritize the western region. |
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2022 |
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2022-09-30 |
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2024-04-22T14:35:46Z |
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2024-04-22T14:35:46Z |
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10.17843/rpmesp.2022.393.11249 |
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eng |
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Rev Peru Med Exp Salud Publica, vol. 39, no. 3, pp. 362–7, Sep. 2022, doi: 10.17843/rpmesp.2022.393.11249. |
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Vol.39 No.3 (2022) |
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3 (2022) |
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S. L. Ruíz-Roa, S. M. Martínez Rojas, and I. A. F. Serna Galeano, “Tuberculosis in the colombian-venezuelan border: geospatial distribution”, Rev Peru Med Exp Salud Publica, vol. 39, no. 3, pp. 362–7, Sep. 2022, doi: 10.17843/rpmesp.2022.393.11249. |
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This work is licensed under a Creative Commons Attribution 4.0 International License. |
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Atribución 4.0 Internacional (CC BY 4.0) |
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Revista Peruana de Medicina Experimental y Salud Publica |
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Perú |
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Ruiz Roa, Silvia Liliana38fb46b80826f9790354abc0b1fd8d7e600Martinez Rojas, Sandra Milenadb7ee203e921ff6f42a87d13098e96f2600Serna Galeano, Ivan Andresdcf5ea296606bf5eb116f7ef7bb393d26002024-04-22T14:35:46Z2024-04-22T14:35:46Z2022-09-30https://repositorio.ufps.edu.co/handle/ufps/699210.17843/rpmesp.2022.393.11249The geospatial distribution of pulmonary and extrapulmonary tuberculosis (TB) morbidity in the municipality of Cucuta in 2019 and 2020 was described by the Kulldorff method using the geographic location and reporting date of incident TB cases. The unit of analysis was the event reported to the National Epidemiological Surveillance System (SIVIGILA). A total of 607 cases were identified in 392 neighborhoods distributed in ten communes. Most cases of pulmonary TB were reported in the northern commune, with the El Salado neighborhood being the most affected repeatedly. Incident cases of extrapulmonary TB did not show patterns of repetition in the distribution between spatial and temporal units. Strategies to mitigate and control the spread of pulmonary infection should prioritize the western region.6 Páginasapplication/pdfengRevista Peruana de Medicina Experimental y Salud PublicaPerúRev Peru Med Exp Salud Publica, vol. 39, no. 3, pp. 362–7, Sep. 2022, doi: 10.17843/rpmesp.2022.393.11249.Vol.39 No.3 (2022)3673 (2022)36239S. L. Ruíz-Roa, S. M. Martínez Rojas, and I. A. F. Serna Galeano, “Tuberculosis in the colombian-venezuelan border: geospatial distribution”, Rev Peru Med Exp Salud Publica, vol. 39, no. 3, pp. 362–7, Sep. 2022, doi: 10.17843/rpmesp.2022.393.11249.This work is licensed under a Creative Commons Attribution 4.0 International License.https://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessAtribución 4.0 Internacional (CC BY 4.0)http://purl.org/coar/access_right/c_abf2https://rpmesp.ins.gob.pe/index.php/rpmesp/article/view/11249Tuberculosis in the colombian-venezuelan border: geospatial distributionArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85Geographic Information SystemsSpatial AnalysisCluster AnalysisGeographic mappingTuberculosisMorbidityWorld Health Organization [Internet]. 2021. Tuberculosis. Key facts. [citado el 27 de marzo del 2021]. Disponible en: https://www.who.int/news-room/fact-sheets/detail/tuberculosis.Osorio C, Aguilar CD, Gómez F. Mortalidad relacionada con tuberculosis en mayores de 50 años en el departamento de Caldas (Colombia) 2010 a 2017. Arch Med (Manizales). 2022;22(1). doi: 10.30554/archmed.22.1.4146.2022.Instituto Nacional de Salud. Tuberculosis Colombia, 2018. [Internet]. Proceso vigilancia y análisis del riesgo en salud pública. [citado el 27 de marzo 2022]. Disponible: https://www.ins.gov.co/buscador-eventos/Informesdeevento/TUBERCULOSIS_2018.pdf#search=tuberculosis%202018.Santos M. Por uma geografia das redes. In: Santos M. A natureza do espaço: técnica e tempo; razão e emoção [internet]. São Paulo: Hucitec; 1997 [citado el 28 de marzo 2022]. Disponoble: https://books.google.com.cu/books?id=JRvh0ebaIXoC&printsec=frontcover#v=onepage&q&f=false.Silva APSC, Souza WV, Albuquerque MFPM. Factores asociados a la ocurrencia de tuberculosis y su distribución espacial en una ciudad brasileña, 1991-2010. Salud Colectiva. 2018; 14(1):77-91. doi: 10.18294/sc.2018.1195.Valbuena-García AM, Rodríguez-Villamizar LA. Análisis espacial en epidemiología: revisión de métodos. Rev Uni Ind Santander Salud. 2018; 50(4): 358-65. doi: 10.18273/revsal.v50n4-2018009.Kulldorff M, Nagarwalla N. Spatial disease clusters: detection and inference. Statistics in medicine. 1995; 14(8): 799–10. doi: 10.1002/sim.4780140809.Shaweno D, Karmakar M, Alene KA , Ragonnet R, Clements A, Trauer JM, et al. Methods used in the spatial analysis of tuberculosis epidemiology: a systematic review. BMC medicine. 2018; 16(1): 93. doi: 10.1186/s12916-018-1178-4.Secretaría de salud de San José de Cúcuta [internet]. Análisis de situación de salud con el modelo de los determinantes sociales en salud, Municipio de San José de Cúcuta. 2017 [cited on 2022 Sep 6]. Available from: https://cucutanortedesantander.micolombiadigital.gov.co/sites/cucutanortedesantander/content/files/000107/5334_asis-municipal2017cucuta.pdfMinisterio de salud y protección social de Colombia. Resolución número 3518 de 2006. [citado el 6 de septiembre del 2022]. Disponible en: https://www.minsalud.gov.co/sites/rid/Lists/BibliotecaDigital/RIDE/DE/DIJ/Decreto-3518-de-2006.pdf.Ministerio de salud y protección social de Colombia. Resolución número 8430 de 1993. [citado el 27 de marzo del 2021]. Disponible en: https://www.minsalud.gov.co/sites/rid/Lists/BibliotecaDigital/RIDE/DE/DIJ/RESOLUCION-8430-DE-1993.PDF.Gehlen M, Nicola MRC, Costa ERD, Cabral VK, de Quadros ELL, Chaves C, et al. Geospatial intelligence and health analitycs: Its application and utility in a city with high tuberculosis incidence in Brazil. Journal of Infection and Public Health. 2019; 12 (5): 681-89. doi: 10.1016/j.jiph.2019.03.012.Addressing poverty in TB control: options for national TB control programmes [internet]. Switzerland: Geneva; 2005 [citado el 28 de marzo 2022]. Disponible en: https://www.cabdirect.org/cabdirect/abstract/20063133335.Shargie EB, Lindtjørn B. Determinants of treatment adherence among smear-positive pulmonary tuberculosis patients in Southern Ethiopia. PLoS medicine.2007; 4(2): e37. doi: 10.1371/journal.pmed.0040037.Kolifarhood G, Khorasani-Zavareh D, Salarilak S, Shoghli A, Khosravi N. Spatial and non-spatial determinants of successful tuberculosis treatment outcomes: An implication of Geographical Information Systems in health policy-making in a developing country. Journal of Epidemiology and Global Health. 2015; 5(3): 221-30. doi: 10.1016/j.jegh.2014.11.001.Paz-Montes LS, Chacon GN, Solano-Becerra E. Realidad socioeconómica de la población migratoria venezolana en Cúcuta. Aibi revista investig. adm. ing.2020; 8(3):138-44. doi: 10.15649/2346030X.695.Navarro-Quintero C, Rueda-Rincón JL, Mendoza-Ojeda JL. Factores asociados al abandono del tratamiento antituberculoso en pacientes con TB Rev cienc. cuidad. 2015; 10(1): 19-7. doi: 10.22463/17949831.275.Organización Mundial de la Salud, Organización Panamericana de salud, 2015 [Internet]. Washington. 67ª Sesión del comité regional de la OMS para las Américas, Plan de acción para la prevención y el control de la tuberculosis. [citado el 04 de abril del 2022]. Disponible en: https://www.paho.org/hq/dmdocuments/2015/CD54-11-s.pdf.Ministerio de Salud y Protección Social y la Organización Panamericana de la Salud. Plan estratégico “hacia el fin de la tuberculosis”. [Internet]: Colombia 2016-2025 [citado el 04 de abril del 2022]. Disponible en: https://www.minsalud.gov.co/sites/rid/Lists/BibliotecaDigital/RIDE/INEC/INTOR/Plan-estrategico-fin-tuberculosis-colombia-2016-2025.pdf.Fusco APB, Arcêncio RA, Yamamura M, Palha PF, Reis AA dos, Alecrim TF de A, et al. Spatial distribution of tuberculosis in a municipality in the interior of São Paulo, 2008-2013. Rev Lat Am Enfermagem. 2017; 25:e2888. doi: 10.1590/1518-8345.1064.2888.Oliveira LB, Costar CRB, Queiroz AFLN, Araújo ME, Sousa KAA, Reis RK. Epidemiological analysis of tuberculosis/hiv coinfection. Cogitare Enferm. 2018; 23(1): e51016. doi: 10.5380/ce.v23i1.51016.Pinto PFPS, Neto FC, Almeida Ribeiro MCS. Tuberculosis among South American immigrants in São Paulo municipality: an analysis in space and time. 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 incorporada en las Obras Colectivas.

b.	Distribuir copias o fonogramas de las Obras, exhibirlas públicamente, ejecutarlas públicamente y/o ponerlas a disposición pública, incluyéndolas como incorporadas en Obras Colectivas, según corresponda.

c.	Distribuir copias de las Obras Derivadas que se generen, exhibirlas públicamente, ejecutarlas públicamente y/o ponerlas a disposición pública.
Los derechos mencionados anteriormente pueden ser ejercidos en todos los medios y formatos, actualmente conocidos o que se inventen en el futuro. Los derechos antes mencionados incluyen el derecho a realizar dichas modificaciones en la medida que sean técnicamente necesarias para ejercer los derechos en otro medio o formatos, pero de otra manera usted no está autorizado para realizar obras derivadas. Todos los derechos no otorgados expresamente por el Licenciante quedan por este medio reservados, incluyendo pero sin limitarse a aquellos que se mencionan en las secciones 4(d) y 4(e).

4. Restricciones.
La licencia otorgada en la anterior Sección 3 está expresamente sujeta y limitada por las siguientes restricciones:

a.	Usted puede distribuir, exhibir públicamente, ejecutar públicamente, o poner a disposición pública la Obra sólo bajo las condiciones de esta Licencia, y Usted debe incluir una copia de esta licencia o del Identificador Universal de Recursos de la misma con cada copia de la Obra que distribuya, exhiba públicamente, ejecute públicamente o ponga a disposición pública. No es posible ofrecer o imponer ninguna condición sobre la Obra que altere o limite las condiciones de esta Licencia o el ejercicio de los derechos de los destinatarios otorgados en este documento. No es posible sublicenciar la Obra. Usted debe mantener intactos todos los avisos que hagan referencia a esta Licencia y a la cláusula de limitación de garantías. Usted no puede distribuir, exhibir públicamente, ejecutar públicamente, o poner a disposición pública la Obra con alguna medida tecnológica que controle el acceso o la utilización de ella de una forma que sea inconsistente con las condiciones de esta Licencia. Lo anterior se aplica a la Obra incorporada a una Obra Colectiva, pero esto no exige que la Obra Colectiva aparte de la obra misma quede sujeta a las condiciones de esta Licencia. Si Usted crea una Obra Colectiva, previo aviso de cualquier Licenciante debe, en la medida de lo posible, eliminar de la Obra Colectiva cualquier referencia a dicho Licenciante o al Autor Original, según lo solicitado por el Licenciante y conforme lo exige la cláusula 4(c).

b.	Usted no puede ejercer ninguno de los derechos que le han sido otorgados en la Sección 3 precedente de modo que estén principalmente destinados o directamente dirigidos a conseguir un provecho comercial o una compensación monetaria privada. El intercambio de la Obra por otras obras protegidas por derechos de autor, ya sea a través de un sistema para compartir archivos digitales (digital file-sharing) o de cualquier otra manera no será considerado como estar destinado principalmente o dirigido directamente a conseguir un provecho comercial o una compensación monetaria privada, siempre que no se realice un pago mediante una compensación monetaria en relación con el intercambio de obras protegidas por el derecho de autor.

c.	Si usted distribuye, exhibe públicamente, ejecuta públicamente o ejecuta públicamente en forma digital la Obra o cualquier Obra Derivada u Obra Colectiva, Usted debe mantener intacta toda la información de derecho de autor de la Obra y proporcionar, de forma razonable según el medio o manera que Usted esté utilizando: (i) el nombre del Autor Original si está provisto (o seudónimo, si fuere aplicable), y/o (ii) el nombre de la parte o las partes que el Autor Original y/o el Licenciante hubieren designado para la atribución (v.g., un instituto patrocinador, editorial, publicación) en la información de los derechos de autor del Licenciante, términos de servicios o de otras formas razonables; el título de la Obra si está provisto; en la medida de lo razonablemente factible y, si está provisto, el Identificador Uniforme de Recursos (Uniform Resource Identifier) que el Licenciante especifica para ser asociado con la Obra, salvo que tal URI no se refiera a la nota sobre los derechos de autor o a la información sobre el licenciamiento de la Obra; y en el caso de una Obra Derivada, atribuir el crédito identificando el uso de la Obra en la Obra Derivada (v.g., "Traducción Francesa de la Obra del Autor Original," o "Guión Cinematográfico basado en la Obra original del Autor Original"). Tal crédito puede ser implementado de cualquier forma razonable; en el caso, sin embargo, de Obras Derivadas u Obras Colectivas, tal crédito aparecerá, como mínimo, donde aparece el crédito de cualquier otro autor comparable y de una manera, al menos, tan destacada como el crédito de otro autor comparable.

d.	Para evitar toda confusión, el Licenciante aclara que, cuando la obra es una composición musical:

i.	Regalías por interpretación y ejecución bajo licencias generales. El Licenciante se reserva el derecho exclusivo de autorizar la ejecución pública o la ejecución pública digital de la obra y de recolectar, sea individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, SAYCO), las regalías por la ejecución pública o por la ejecución pública digital de la obra (por ejemplo Webcast) licenciada bajo licencias generales, si la interpretación o ejecución de la obra está primordialmente orientada por o dirigida a la obtención de una ventaja comercial o una compensación monetaria privada.

ii.	Regalías por Fonogramas. El Licenciante se reserva el derecho exclusivo de recolectar, individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, los consagrados por la SAYCO), una agencia de derechos musicales o algún agente designado, las regalías por cualquier fonograma que Usted cree a partir de la obra (“versión cover”) y distribuya, en los términos del régimen de derechos de autor, si la creación o distribución de esa versión cover está primordialmente destinada o dirigida a obtener una ventaja comercial o una compensación monetaria privada.

e.	Gestión de Derechos de Autor sobre Interpretaciones y Ejecuciones Digitales (WebCasting). Para evitar toda confusión, el Licenciante aclara que, cuando la obra sea un fonograma, el Licenciante se reserva el derecho exclusivo de autorizar la ejecución pública digital de la obra (por ejemplo, webcast) y de recolectar, individualmente o a través de una sociedad de gestión colectiva de derechos de autor y derechos conexos (por ejemplo, ACINPRO), las regalías por la ejecución pública digital de la obra (por ejemplo, webcast), sujeta a las disposiciones aplicables del régimen de Derecho de Autor, si esta ejecución pública digital está primordialmente dirigida a obtener una ventaja comercial o una compensación monetaria privada.

5. Representaciones, Garantías y Limitaciones de Responsabilidad.
A MENOS QUE LAS PARTES LO ACORDARAN DE OTRA FORMA POR ESCRITO, EL LICENCIANTE OFRECE LA OBRA (EN EL ESTADO EN EL QUE SE ENCUENTRA) “TAL CUAL”, SIN BRINDAR GARANTÍAS DE CLASE ALGUNA RESPECTO DE LA OBRA, YA SEA EXPRESA, IMPLÍCITA, LEGAL O CUALQUIERA OTRA, INCLUYENDO, SIN LIMITARSE A ELLAS, GARANTÍAS DE TITULARIDAD, COMERCIABILIDAD, ADAPTABILIDAD O ADECUACIÓN A PROPÓSITO DETERMINADO, AUSENCIA DE INFRACCIÓN, DE AUSENCIA DE DEFECTOS LATENTES O DE OTRO TIPO, O LA PRESENCIA O AUSENCIA DE ERRORES, SEAN O NO DESCUBRIBLES (PUEDAN O NO SER ESTOS DESCUBIERTOS). ALGUNAS JURISDICCIONES NO PERMITEN LA EXCLUSIÓN DE GARANTÍAS IMPLÍCITAS, EN CUYO CASO ESTA EXCLUSIÓN PUEDE NO APLICARSE A USTED.

6. Limitación de responsabilidad.
A MENOS QUE LO EXIJA EXPRESAMENTE LA LEY APLICABLE, EL LICENCIANTE NO SERÁ RESPONSABLE ANTE USTED POR DAÑO ALGUNO, SEA POR RESPONSABILIDAD EXTRACONTRACTUAL, PRECONTRACTUAL O CONTRACTUAL, OBJETIVA O SUBJETIVA, SE TRATE DE DAÑOS MORALES O PATRIMONIALES, DIRECTOS O INDIRECTOS, PREVISTOS O IMPREVISTOS PRODUCIDOS POR EL USO DE ESTA LICENCIA O DE LA OBRA, AUN CUANDO EL LICENCIANTE HAYA SIDO ADVERTIDO DE LA POSIBILIDAD DE DICHOS DAÑOS. ALGUNAS LEYES NO PERMITEN LA EXCLUSIÓN DE CIERTA RESPONSABILIDAD, EN CUYO CASO ESTA EXCLUSIÓN PUEDE NO APLICARSE A USTED.

7. Término.

a.	Esta Licencia y los derechos otorgados en virtud de ella terminarán automáticamente si Usted infringe alguna condición establecida en ella. Sin embargo, los individuos o entidades que han recibido Obras Derivadas o Colectivas de Usted de conformidad con esta Licencia, no verán terminadas sus licencias, siempre que estos individuos o entidades sigan cumpliendo íntegramente las condiciones de estas licencias. Las Secciones 1, 2, 5, 6, 7, y 8 subsistirán a cualquier terminación de esta Licencia.

b.	Sujeta a las condiciones y términos anteriores, la licencia otorgada aquí es perpetua (durante el período de vigencia de los derechos de autor de la obra). No obstante lo anterior, el Licenciante se reserva el derecho a publicar y/o estrenar la Obra bajo condiciones de licencia diferentes o a dejar de distribuirla en los términos de esta Licencia en cualquier momento; en el entendido, sin embargo, que esa elección no servirá para revocar esta licencia o que deba ser otorgada , bajo los términos de esta licencia), y esta licencia continuará en pleno vigor y efecto a menos que sea terminada como se expresa atrás. La Licencia revocada continuará siendo plenamente vigente y efectiva si no se le da término en las condiciones indicadas anteriormente.

8. Varios.

a.	Cada vez que Usted distribuya o ponga a disposición pública la Obra o una Obra Colectiva, el Licenciante ofrecerá al destinatario una licencia en los mismos términos y condiciones que la licencia otorgada a Usted bajo esta Licencia.

b.	Si alguna disposición de esta Licencia resulta invalidada o no exigible, según la legislación vigente, esto no afectará ni la validez ni la aplicabilidad del resto de condiciones de esta Licencia y, sin acción adicional por parte de los sujetos de este acuerdo, aquélla se entenderá reformada lo mínimo necesario para hacer que dicha disposición sea válida y exigible.

c.	Ningún término o disposición de esta Licencia se estimará renunciada y ninguna violación de ella será consentida a menos que esa renuncia o consentimiento sea otorgado por escrito y firmado por la parte que renuncie o consienta.

d.	Esta Licencia refleja el acuerdo pleno entre las partes respecto a la Obra aquí licenciada. No hay arreglos, acuerdos o declaraciones respecto a la Obra que no estén especificados en este documento. El Licenciante no se verá limitado por ninguna disposición adicional que pueda surgir en alguna comunicación emanada de Usted. Esta Licencia no puede ser modificada sin el consentimiento mutuo por escrito del Licenciante y Usted.
0000-0002-4649-094438fb46b80826f9790354abc0b1fd8d7e6000000-0003-1447-6862db7ee203e921ff6f42a87d13098e96f26000000-0002-4414-8475dcf5ea296606bf5eb116f7ef7bb393d2600 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