Differential anti-proliferative effect on K562 leukemia cells of Lippia alba (Verbenaceae) essential oils produced under diverse growing, collection and extraction conditions
9 p.
- Autores:
-
García Sánchez, Liliana Torcoroma
Leal, Andrés Felipe
Moreno Moreno, Erika Marcela
Stashenko, Elena E.
Arteaga, H. José
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2017
- Institución:
- Universidad de Santander
- Repositorio:
- Repositorio Universidad de Santander
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.udes.edu.co:001/3428
- Acceso en línea:
- https://repositorio.udes.edu.co/handle/001/3428
- Palabra clave:
- Lippia alba
Essential oils
Citral
Carvone
Caryophyllene oxide
K562 cells
- Rights
- openAccess
- License
- Derechos Reservados - Universidad de Santander, 2017
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Differential anti-proliferative effect on K562 leukemia cells of Lippia alba (Verbenaceae) essential oils produced under diverse growing, collection and extraction conditions |
| title |
Differential anti-proliferative effect on K562 leukemia cells of Lippia alba (Verbenaceae) essential oils produced under diverse growing, collection and extraction conditions |
| spellingShingle |
Differential anti-proliferative effect on K562 leukemia cells of Lippia alba (Verbenaceae) essential oils produced under diverse growing, collection and extraction conditions Lippia alba Essential oils Citral Carvone Caryophyllene oxide K562 cells |
| title_short |
Differential anti-proliferative effect on K562 leukemia cells of Lippia alba (Verbenaceae) essential oils produced under diverse growing, collection and extraction conditions |
| title_full |
Differential anti-proliferative effect on K562 leukemia cells of Lippia alba (Verbenaceae) essential oils produced under diverse growing, collection and extraction conditions |
| title_fullStr |
Differential anti-proliferative effect on K562 leukemia cells of Lippia alba (Verbenaceae) essential oils produced under diverse growing, collection and extraction conditions |
| title_full_unstemmed |
Differential anti-proliferative effect on K562 leukemia cells of Lippia alba (Verbenaceae) essential oils produced under diverse growing, collection and extraction conditions |
| title_sort |
Differential anti-proliferative effect on K562 leukemia cells of Lippia alba (Verbenaceae) essential oils produced under diverse growing, collection and extraction conditions |
| dc.creator.fl_str_mv |
García Sánchez, Liliana Torcoroma Leal, Andrés Felipe Moreno Moreno, Erika Marcela Stashenko, Elena E. Arteaga, H. José |
| dc.contributor.author.spa.fl_str_mv |
García Sánchez, Liliana Torcoroma Leal, Andrés Felipe Moreno Moreno, Erika Marcela Stashenko, Elena E. Arteaga, H. José |
| dc.subject.proposal.eng.fl_str_mv |
Lippia alba Essential oils Citral Carvone Caryophyllene oxide K562 cells |
| topic |
Lippia alba Essential oils Citral Carvone Caryophyllene oxide K562 cells |
| description |
9 p. |
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2017 |
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2017-02 |
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2019-07-18T19:28:20Z |
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2019-07-18T19:28:20Z |
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10.1016/j.indcrop.2016.11.057 |
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0926-6690 |
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https://repositorio.udes.edu.co/handle/001/3428 |
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10.1016/j.indcrop.2016.11.057 0926-6690 |
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eng |
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eng |
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Industrial Crops and Products |
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Derechos Reservados - Universidad de Santander, 2017 |
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Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0) |
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application/pdf |
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García Sánchez, Liliana Torcoroma5b6d6a1a-21c5-4db6-8dc3-3f5c61c9190f-1Leal, Andrés Felipeef7a77fd-706d-4bed-a590-fd2ba50df9f0-1Moreno Moreno, Erika Marcela43351170-bbb9-4abc-adc1-0e9ffa35532c-1Stashenko, Elena E.9bce8ceb-c05b-4ad6-9b18-c456b7d82339-1Arteaga, H. Joséc6d8eb1c-09dc-4bc3-8040-32caadeb3239-12019-07-18T19:28:20Z2019-07-18T19:28:20Z2017-029 p.Lippia alba (Verbenaceae Family) is an aromatic shrub native to Latin America, with recognized medicinal properties and a well-known high phenotypical plasticity in response to environmental factors. In order to identify the parameters that potentiate its in vitro anti-proliferative effect on human leukemia cells (K562), a matrix was designed for the production of 76 essential oils (EOs) with variations in plant growing season, harvested part from the plant, and preservation and distillation material conditions. The results show that EOs obtained from the same L. alba chemotype (Citral or Carvone), but acquired under different environmental or extraction conditions, presented significant differences in their primary components, oil yield, and cytotoxic activity on K562 cells. Citral EOs produced under diverse conditions displayed a cytotoxic effect on tumour cells ranging from 54 to 95% (IS 1.8–8.6) and IC50 from 13 to 38.8 μg/mL. The differences in antiproliferative activity were significantly correlated with variations in the β-caryophyllene oxide concentration. These results show the value of using standardized production conditions for the commercial utilization of L. alba EOs.application/pdf10.1016/j.indcrop.2016.11.0570926-6690https://repositorio.udes.edu.co/handle/001/3428engIndustrial Crops and ProductsDerechos Reservados - Universidad de Santander, 2017info:eu-repo/semantics/openAccessAtribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)https://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2https://www.sciencedirect.com/science/article/pii/S0926669016308202?via%3DihubLippia albaEssential oilsCitralCarvoneCaryophyllene oxideK562 cellsDifferential anti-proliferative effect on K562 leukemia cells of Lippia alba (Verbenaceae) essential oils produced under diverse growing, collection and extraction conditionsArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85PublicationBRANDED_PREVIEWDifferential anti-proliferative effect on K562 leukemia cells of Lippia alba (Verbenaceae) essential oils produced under diverse growing, collection and extraction conditions..PNG.preview.jpgDifferential anti-proliferative effect on K562 leukemia cells of Lippia alba (Verbenaceae) essential oils produced under diverse growing, collection and extraction conditions..PNG.preview.jpgGenerated Branded Previewimage/jpeg6200https://repositorio.udes.edu.co/bitstreams/e618f951-503d-4dff-8cea-d877e6daaf20/download7843492c174d77e4e7d25481074f5c38MD54THUMBNAILDifferential anti-proliferative effect on K562 leukemia cells of Lippia alba (Verbenaceae) essential oils produced under diverse growing, collection and extraction conditions..PNG.jpgDifferential anti-proliferative effect on K562 leukemia cells of Lippia alba (Verbenaceae) essential oils produced under diverse growing, collection and extraction conditions..PNG.jpgUDESimage/jpeg1697https://repositorio.udes.edu.co/bitstreams/2ea6e652-8f9d-47c3-9f0a-eecf7b5614fa/download6381f005bac5f4a0c5491e7c7197d55bMD53Differential anti-proliferative effect on K562 leukemia cells of Lippia alba (Verbenaceae) essential oils produced under diverse growing, collection and extraction conditions.pdf.jpgDifferential anti-proliferative effect on K562 leukemia cells of Lippia alba (Verbenaceae) essential oils produced under diverse growing, collection and extraction conditions.pdf.jpgGenerated Thumbnailimage/jpeg6011https://repositorio.udes.edu.co/bitstreams/bdf08f77-2ae9-4e59-ae82-9764bf18314b/download3f9ff89a09eb6a0c2d270118c3113bd9MD57LICENSElicense.txtlicense.txttext/plain; charset=utf-859https://repositorio.udes.edu.co/bitstreams/77fa528b-e19e-4991-b598-b8fb15e42f3b/download38d94cf55aa1bf2dac1a736ac45c881cMD52ORIGINALDifferential anti-proliferative effect on K562 leukemia cells of Lippia alba (Verbenaceae) essential oils produced under diverse growing, collection and extraction conditions.pdfDifferential anti-proliferative effect on K562 leukemia cells of Lippia alba (Verbenaceae) essential oils produced under diverse growing, collection and extraction conditions.pdfapplication/pdf254613https://repositorio.udes.edu.co/bitstreams/973b0448-4c88-4e67-ae84-8e52ed95d453/download2673747db760173bb1e51b7c805fc958MD55TEXTDifferential anti-proliferative effect on K562 leukemia cells of Lippia alba (Verbenaceae) essential oils produced under diverse growing, collection and extraction conditions.pdf.txtDifferential anti-proliferative effect on K562 leukemia cells of Lippia alba (Verbenaceae) essential oils produced under diverse growing, collection and extraction conditions.pdf.txtExtracted texttext/plain5https://repositorio.udes.edu.co/bitstreams/f8e3bd18-8188-41af-b73f-72e8a624aa92/download5dbe86c1111d64f45ba435df98fdc825MD56001/3428oai:repositorio.udes.edu.co:001/34282023-10-11 11:04:24.799https://creativecommons.org/licenses/by-nc/4.0/Derechos Reservados - Universidad de Santander, 2017https://repositorio.udes.edu.coRepositorio Universidad de Santandersoporte@metabiblioteca.comTGljZW5jaWEgZGUgUHVibGljYWNpw7NuIFVERVMKRGlyZWN0cmljZXMgZGUgVVNPIHkgQUNDRVNPCgo= |