Sensory aspects in myasthenia gravis : A translational approach
10 p.
- Autores:
-
Leon-Sarmiento, Fidias E.
Leon-Ariza, Juan S.
Prada, Diddier G.
Leon-Ariza, Daniel S.
Rizzo Sierra, Carlos V.
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2016
- Institución:
- Universidad de Santander
- Repositorio:
- Repositorio Universidad de Santander
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.udes.edu.co:001/3450
- Acceso en línea:
- https://repositorio.udes.edu.co/handle/001/3450
- Palabra clave:
- Myasthenia gravis
Muscle weakness
Pain
Synapses
Acetylcholine
- Rights
- openAccess
- License
- Derechos Reservados - Journal of the Neurological Sciences, 2016
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Sensory aspects in myasthenia gravis : A translational approach |
| title |
Sensory aspects in myasthenia gravis : A translational approach |
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Sensory aspects in myasthenia gravis : A translational approach Myasthenia gravis Muscle weakness Pain Synapses Acetylcholine |
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Sensory aspects in myasthenia gravis : A translational approach |
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Sensory aspects in myasthenia gravis : A translational approach |
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Sensory aspects in myasthenia gravis : A translational approach |
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Sensory aspects in myasthenia gravis : A translational approach |
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Sensory aspects in myasthenia gravis : A translational approach |
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Leon-Sarmiento, Fidias E. Leon-Ariza, Juan S. Prada, Diddier G. Leon-Ariza, Daniel S. Rizzo Sierra, Carlos V. |
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Leon-Sarmiento, Fidias E. Leon-Ariza, Juan S. Prada, Diddier G. Leon-Ariza, Daniel S. Rizzo Sierra, Carlos V. |
| dc.subject.proposal.eng.fl_str_mv |
Myasthenia gravis Muscle weakness Pain Synapses Acetylcholine |
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Myasthenia gravis Muscle weakness Pain Synapses Acetylcholine |
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10 p. |
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2016 |
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2016-09-15 |
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2019-07-23T15:43:09Z |
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0022-510X |
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eng |
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eng |
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Journal of the Neurological Sciences |
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Leon-Sarmiento, Fidias E.46042405-eca5-442f-84ba-2f81d90d50b5-1Leon-Ariza, Juan S.1d9c7815-4d9d-4d10-b3ab-1adaffa2c3d8-1Prada, Diddier G.f2037094-7867-457f-b663-ca1f1f20108c-1Leon-Ariza, Daniel S.376c7434-3d7f-451a-ac99-8b1be55d3bde-1Rizzo Sierra, Carlos V.f9ca4843-019b-4761-8a7c-21720356d44d-12019-07-23T15:43:09Z2019-07-23T15:43:09Z2016-09-1510 p.Myasthenia gravis is a paradigmatic muscle disorder characterized by abnormal fatigue and muscle weakness that worsens with activities and improves with rest. Clinical and research studies done on nicotinic acetylcholine receptors have advanced our knowledge of the muscle involvement in myasthenia. Current views still state that sensory deficits are not “features of myasthenia gravis”. This article discusses the gap that exists on sensory neural transmission in myasthenia that has remained after > 300 years of research in this neurological disorder. We outline the neurobiological characteristics of sensory and motor synapses, reinterpret the nanocholinergic commonalities that exist in both sensory and motor pathways, discuss the clinical findings on altered sensory pathways in myasthenia, and propose a novel way to score anomalies resulting from multineuronal inability associated sensory troubles due to eugenic nanocholinergic instability and autoimmunity. This medicine-based evidence could serve as a template to further identify novel targets for studying new medications that may offer a better therapeutic benefit in both sensory and motor dysfunction for patients. Importantly, this review may help to re-orient current practices in myasthenia.application/pdf10.1016/j.jns.2016.07.0140022-510Xhttps://repositorio.udes.edu.co/handle/001/3450engJournal of the Neurological SciencesDerechos Reservados - Journal of the Neurological Sciences, 2016info:eu-repo/semantics/openAccessAtribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)https://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2https://www.sciencedirect.com/science/article/pii/S0022510X16304269?via%3DihubMyasthenia gravisMuscle weaknessPainSynapsesAcetylcholineSensory aspects in myasthenia gravis : A translational approachArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85PublicationTEXTSensory aspects in myasthenia gravis. A translational approach.pdf.txtSensory aspects in myasthenia gravis. A translational approach.pdf.txtExtracted texttext/plain2https://repositorio.udes.edu.co/bitstreams/5258b202-9436-4213-a24f-0a193b1013d0/downloadd784fa8b6d98d27699781bd9a7cf19f0MD56BRANDED_PREVIEWSensory aspects in myasthenia gravis. A translational approach.PNG.preview.jpgSensory aspects in myasthenia gravis. A translational approach.PNG.preview.jpgGenerated Branded Previewimage/jpeg5687https://repositorio.udes.edu.co/bitstreams/6b0e7498-5c98-4026-8bae-3191537fe0ef/downloadda6b3d94cf2a486f7e0d20f9097ebff9MD54THUMBNAILSensory aspects in myasthenia gravis. A translational approach.PNG.jpgSensory aspects in myasthenia gravis. A translational approach.PNG.jpgUDESimage/jpeg1383https://repositorio.udes.edu.co/bitstreams/ebb92423-f666-41f6-9173-178df9de16b4/downloadfa999b8f8d4044e3c11ece8261dc638eMD53Sensory aspects in myasthenia gravis. A translational approach.pdf.jpgSensory aspects in myasthenia gravis. A translational approach.pdf.jpgGenerated Thumbnailimage/jpeg1550https://repositorio.udes.edu.co/bitstreams/a9165064-0357-4422-850b-4aa14be3f846/downloade796b346d9cc09a4b027768d12624628MD57LICENSElicense.txtlicense.txttext/plain; charset=utf-859https://repositorio.udes.edu.co/bitstreams/b3de6e14-f076-4df7-a07d-690bec7d8962/download38d94cf55aa1bf2dac1a736ac45c881cMD52ORIGINALSensory aspects in myasthenia gravis. A translational approach.pdfSensory aspects in myasthenia gravis. A translational approach.pdfapplication/pdf266580https://repositorio.udes.edu.co/bitstreams/b124e51e-784c-4cf5-bff1-c42eb6dbb8fb/downloadb19548f363b0c7f09c5dea641149fb50MD55001/3450oai:repositorio.udes.edu.co:001/34502023-10-10 09:20:20.231https://creativecommons.org/licenses/by-nc/4.0/Derechos Reservados - Journal of the Neurological Sciences, 2016https://repositorio.udes.edu.coRepositorio Universidad de Santandersoporte@metabiblioteca.comTGljZW5jaWEgZGUgUHVibGljYWNpw7NuIFVERVMKRGlyZWN0cmljZXMgZGUgVVNPIHkgQUNDRVNPCgo= |