Phosphine-free Suzuki cross-coupling reaction using an efficient and reusable Pd catalyst in an aqueous medium under microwave irradia
We report here an improved, highly efficient, and general method for the ligand-free Suzuki cross-coupling reaction to the synthesis of biaryls, bipyridyls, thienylpyridine, and allylphenols. Microwave irradiation of (het)aryl halides and (hetaryl, allyl)arylboronic acid N-methyl-iminodiacetic acid...
- Autores:
-
Da Silva, Joaquim F. M.
De Almeida, Natália P.
Yepes Pérez, Andres Felipe
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2015
- Institución:
- Universidad de Santander
- Repositorio:
- Repositorio Universidad de Santander
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.udes.edu.co:001/3503
- Acceso en línea:
- https://repositorio.udes.edu.co/handle/001/3503
- Palabra clave:
- Microwave irradiation
Pd EnCat30
Phosphine-free reactions
Organoboronic acid MIDA ester
Suzuki coupling
- Rights
- openAccess
- License
- Derechos Reservados - Taylor & Francis, 2015
| Summary: | We report here an improved, highly efficient, and general method for the ligand-free Suzuki cross-coupling reaction to the synthesis of biaryls, bipyridyls, thienylpyridine, and allylphenols. Microwave irradiation of (het)aryl halides and (hetaryl, allyl)arylboronic acid N-methyl-iminodiacetic acid (MIDA) ester, using polyurea microencapsulated palladium catalyst (Pd EnCat 30), gave the coupling adducts 1a–x in excellent yields in just 10–18 min. |
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