Secondary CV Prevention in South America in a Community Setting : The PURE Study
9 p.
- Autores:
-
Avezum, Alvaro
Oliveira, Gustavo
Lanas, Fernando
Lopez-Jaramillo, Patricio
Diaz, Rafael
Miranda, J. Jaime
Seron, Pamela
Camacho López, Paul Anthony
Orlandini, Andres
Ortiz, Antonio Bernabe
Mattos, Antônio Cordeiro
Islam, Shofiqul
Rangarajan, Sumathy
Teo, Koon
Yusuf, Salim
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2017
- Institución:
- Universidad de Santander
- Repositorio:
- Repositorio Universidad de Santander
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.udes.edu.co:001/3415
- Acceso en línea:
- https://repositorio.udes.edu.co/handle/001/3415
- Palabra clave:
- Secondary CV Prevention
South America
- Rights
- openAccess
- License
- Derechos Reservados - Global Heart, 2017
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Secondary CV Prevention in South America in a Community Setting : The PURE Study |
| title |
Secondary CV Prevention in South America in a Community Setting : The PURE Study |
| spellingShingle |
Secondary CV Prevention in South America in a Community Setting : The PURE Study Secondary CV Prevention South America |
| title_short |
Secondary CV Prevention in South America in a Community Setting : The PURE Study |
| title_full |
Secondary CV Prevention in South America in a Community Setting : The PURE Study |
| title_fullStr |
Secondary CV Prevention in South America in a Community Setting : The PURE Study |
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Secondary CV Prevention in South America in a Community Setting : The PURE Study |
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Secondary CV Prevention in South America in a Community Setting : The PURE Study |
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Avezum, Alvaro Oliveira, Gustavo Lanas, Fernando Lopez-Jaramillo, Patricio Diaz, Rafael Miranda, J. Jaime Seron, Pamela Camacho López, Paul Anthony Orlandini, Andres Ortiz, Antonio Bernabe Mattos, Antônio Cordeiro Islam, Shofiqul Rangarajan, Sumathy Teo, Koon Yusuf, Salim |
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Avezum, Alvaro Oliveira, Gustavo Lanas, Fernando Lopez-Jaramillo, Patricio Diaz, Rafael Miranda, J. Jaime Seron, Pamela Camacho López, Paul Anthony Orlandini, Andres Ortiz, Antonio Bernabe Mattos, Antônio Cordeiro Islam, Shofiqul Rangarajan, Sumathy Teo, Koon Yusuf, Salim |
| dc.subject.proposal.eng.fl_str_mv |
Secondary CV Prevention South America |
| topic |
Secondary CV Prevention South America |
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9 p. |
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2017 |
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2017-12 |
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2019-07-17T19:16:12Z |
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10.1016/j.gheart.2016.06.001 |
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2211-8160 |
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https://repositorio.udes.edu.co/handle/001/3415 |
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10.1016/j.gheart.2016.06.001 2211-8160 |
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eng |
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eng |
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Global Heart |
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Derechos Reservados - Global Heart, 2017 |
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Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0) |
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application/pdf |
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https://www.sciencedirect.com/science/article/pii/S2211816016307001?via%3Dihub |
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Avezum, Alvaro8b920360-abb2-4ec8-b5ee-4e3f4e0b11eb-1Oliveira, Gustavoa15f3ebc-753b-4b0a-9923-997eeb9ad7ba-1Lanas, Fernandod22b7fe4-9f1f-4028-a22b-be782ef03d3c-1Lopez-Jaramillo, Patricio9a71267b-dcb0-4d31-b37d-2d30be58d4d2-1Diaz, Rafaelf2be4a74-501a-4e63-8bbd-965cbcf8c57b-1Miranda, J. Jaime58401de2-0444-4620-ab95-0248923d21d6-1Seron, Pamela95c6e76c-9891-4782-a399-b592acec2294-1Camacho López, Paul Anthony594e3832-d941-4df3-b3cc-a2c088dca74c-1Orlandini, Andrescbafea09-3a82-4064-a22f-d34a0e7583d4-1Ortiz, Antonio Bernabe59542b81-91d1-4a79-a187-7c3438e753b0-1Mattos, Antônio Cordeirob80e4808-d46d-4bcb-9cdc-dcc7919fe790-1Islam, Shofiqule02df6ce-a317-49c4-8ebd-72d82c266011-1Rangarajan, Sumathy5466c363-e515-4bd2-8537-eb839320f385-1Teo, Koon60475883-56ab-4acc-833d-b027ad828534-1Yusuf, Salim06a836b5-f5e3-41d9-a516-9cc46e5d7948-12019-07-17T19:16:12Z2019-07-17T19:16:12Z2017-129 p.Background Despite the availability of evidence-based therapies, there is no information on the use of medications for the secondary prevention of cardiovascular disease in urban and rural community settings in South America. Objectives This study sought to assess the use, and its predictors, of effective secondary prevention therapies in individuals with a history of coronary heart disease (CHD) or stroke. Methods In the PURE (Prospective Urban Rural Epidemiological) study, we enrolled 24,713 individuals from South America ages 35 to 70 years from 97 rural and urban communities in Argentina, Brazil, Chile, and Colombia. We assessed the use of proven therapies with standardized questionnaires. We report estimates of drug use at national, community, and individual levels and the independent predictors of their utilization through a multivariable analysis model. Results Of 24,713 individuals, 910 had a self-reported CHD event (at a median of 5 years earlier) and 407 had stroke (6 years earlier). The proportions of individuals with CHD who received antiplatelet medications (30.1%), beta-blockers (34.2%), angiotensin-converting enzyme inhibitors, or angiotensin-receptor blockers (36.0%), or statins (18.0%) were low; with even lower proportions among stroke patients (antiplatelets 24.3%, angiotensin-converting enzyme inhibitors/angiotensin-receptor blockers 37.6%, statins 9.8%). A substantial proportion of patients did not receive any proven therapy (CHD 31%, stroke 54%). A minority of patients received either all 4 (4.1%) or 3 proven therapies (3.3%). Male sex, age >60 years, better education, more wealth, urban location, diabetes, and obesity were associated with higher rates of medication use. In a multivariable model, markers of wealth had the largest impact in secondary prevention. Conclusions There are large gaps in the use of proven medications for secondary prevention of cardiovascular disease in South America. Strategies to improve the sustained use of these medications will likely reduce cardiovascular disease burden substantially.application/pdf10.1016/j.gheart.2016.06.0012211-8160https://repositorio.udes.edu.co/handle/001/3415engGlobal HeartDerechos Reservados - Global Heart, 2017info:eu-repo/semantics/openAccessAtribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)https://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2https://www.sciencedirect.com/science/article/pii/S2211816016307001?via%3DihubSecondary CV PreventionSouth AmericaSecondary CV Prevention in South America in a Community Setting : The PURE StudyArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85PublicationTEXTSecondary CV Prevention in South America in a Community Setting. 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