Global mortality variations in patients with heart failure : Results from the International Congestive Heart Failure (INTER-CHF) prospective cohort study
8 p.
- Autores:
-
Lopez-Jaramillo, Patricio
Dokainish, Hisham
Teo, Koon
Zhu, Jun
Roy, Ambuj
AlHabib, Khalid F.
ElSayed, Ahmed
Palileo Villaneuva, Lia
Karaye, Kamilu
Yusoff, Khalid
Orlandini, Andres
Sliwa, Karen
Mondo, Charles
Lanas, Fernando
Prabhakaran, Dorairaj
Badr, Amr
Elmaghawry, Mohamed
Damasceno, Albertino
Tibazarwa, Kemi
Belley Cote, Emilie
Balasubramanian, Kumar
Islam, Shofiqul
Yacoub, Magdi H.
Huffman, Mark D.
Harkness, Karen
Grinvalds, Alex
McKelvie, Robert
Bangdiwala, Shrikant I.
Yusuf, Salim
On behalf of the INTER-CHF Investigators.
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2017
- Institución:
- Universidad de Santander
- Repositorio:
- Repositorio Universidad de Santander
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.udes.edu.co:001/3203
- Acceso en línea:
- https://repositorio.udes.edu.co/handle/001/3203
- Palabra clave:
- Global
Mortality
Heart failure
INTER-CHF
- Rights
- closedAccess
- License
- Derechos Reservados - Universidad de Santander, 2017
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Global mortality variations in patients with heart failure : Results from the International Congestive Heart Failure (INTER-CHF) prospective cohort study |
| title |
Global mortality variations in patients with heart failure : Results from the International Congestive Heart Failure (INTER-CHF) prospective cohort study |
| spellingShingle |
Global mortality variations in patients with heart failure : Results from the International Congestive Heart Failure (INTER-CHF) prospective cohort study Global Mortality Heart failure INTER-CHF |
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Global mortality variations in patients with heart failure : Results from the International Congestive Heart Failure (INTER-CHF) prospective cohort study |
| title_full |
Global mortality variations in patients with heart failure : Results from the International Congestive Heart Failure (INTER-CHF) prospective cohort study |
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Global mortality variations in patients with heart failure : Results from the International Congestive Heart Failure (INTER-CHF) prospective cohort study |
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Global mortality variations in patients with heart failure : Results from the International Congestive Heart Failure (INTER-CHF) prospective cohort study |
| title_sort |
Global mortality variations in patients with heart failure : Results from the International Congestive Heart Failure (INTER-CHF) prospective cohort study |
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Lopez-Jaramillo, Patricio Dokainish, Hisham Teo, Koon Zhu, Jun Roy, Ambuj AlHabib, Khalid F. ElSayed, Ahmed Palileo Villaneuva, Lia Karaye, Kamilu Yusoff, Khalid Orlandini, Andres Sliwa, Karen Mondo, Charles Lanas, Fernando Prabhakaran, Dorairaj Badr, Amr Elmaghawry, Mohamed Damasceno, Albertino Tibazarwa, Kemi Belley Cote, Emilie Balasubramanian, Kumar Islam, Shofiqul Yacoub, Magdi H. Huffman, Mark D. Harkness, Karen Grinvalds, Alex McKelvie, Robert Bangdiwala, Shrikant I. Yusuf, Salim On behalf of the INTER-CHF Investigators. |
| dc.contributor.author.spa.fl_str_mv |
Lopez-Jaramillo, Patricio Dokainish, Hisham Teo, Koon Zhu, Jun Roy, Ambuj AlHabib, Khalid F. ElSayed, Ahmed Palileo Villaneuva, Lia Karaye, Kamilu Yusoff, Khalid Orlandini, Andres Sliwa, Karen Mondo, Charles Lanas, Fernando Prabhakaran, Dorairaj Badr, Amr Elmaghawry, Mohamed Damasceno, Albertino Tibazarwa, Kemi Belley Cote, Emilie Balasubramanian, Kumar Islam, Shofiqul Yacoub, Magdi H. Huffman, Mark D. Harkness, Karen Grinvalds, Alex McKelvie, Robert Bangdiwala, Shrikant I. Yusuf, Salim |
| dc.contributor.author.eng.fl_str_mv |
On behalf of the INTER-CHF Investigators. |
| dc.subject.proposal.eng.fl_str_mv |
Global Mortality Heart failure INTER-CHF |
| topic |
Global Mortality Heart failure INTER-CHF |
| description |
8 p. |
| publishDate |
2017 |
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2017-07-01 |
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2019-06-25T17:08:31Z |
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2019-06-25T17:08:31Z |
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Artículo de revista |
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10.1016/S2214-109X(17)30196-1 |
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2214-109X |
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eng |
| language |
eng |
| dc.relation.ispartof.eng.fl_str_mv |
The Lancet Global Health |
| dc.rights.spa.fl_str_mv |
Derechos Reservados - Universidad de Santander, 2017 |
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Lopez-Jaramillo, Patricio9a71267b-dcb0-4d31-b37d-2d30be58d4d2-1Dokainish, Hisham18ada750-a3b5-424f-a7c2-ec2ddfcbdcbe-1Teo, Koon60475883-56ab-4acc-833d-b027ad828534-1Zhu, Jund97cdbd2-6a82-430c-abfe-c978f085997e-1Roy, Ambujc247897d-97d3-48f3-adfa-288fdb8cde6c-1AlHabib, Khalid F.49cf9a4d-2bdf-4356-b613-9ef98a77f4c3-1ElSayed, Ahmed229271f2-22a0-437e-87c2-32523a0ed27d-1Palileo Villaneuva, Lia2b573bb2-4330-4cd8-be37-86758a57f4e9-1Karaye, Kamilua9ba4559-0d88-4ca6-a615-65a2f3acea58-1Yusoff, Khalid933db13d-f5bb-4ea6-91a5-68eea1ca9ffc-1Orlandini, Andrescbafea09-3a82-4064-a22f-d34a0e7583d4-1Sliwa, Karen7ff2b80f-9412-4d65-99cd-7d01d5578687-1Mondo, Charles7aafecbd-7e11-4e0b-8dc7-ddb7ded2b812-1Lanas, Fernandod22b7fe4-9f1f-4028-a22b-be782ef03d3c-1Prabhakaran, Dorairaj360f4921-c217-4323-bd85-794b4e28a513-1Badr, Amrc201eaa8-69d1-4b23-8a29-fd296fb216a0-1Elmaghawry, Mohamedd44dc25b-d4dc-4e90-a93f-9cf669e174f4-1Damasceno, Albertino2500b2be-4fb3-45c8-ba40-645dd73600aa-1Tibazarwa, Kemi4c43052d-51d8-4883-bd70-78fbedff32bf-1Belley Cote, Emiliee1675a21-4ca8-4ef7-a46d-a1709da7c08f-1Balasubramanian, Kumar0a03c747-a4c9-4824-9135-7afdf7a9b352-1Islam, Shofiqule02df6ce-a317-49c4-8ebd-72d82c266011-1Yacoub, Magdi H.f35b6f55-f35f-411a-b877-e6f80f5f26a5-1Huffman, Mark D.cd624a24-693b-413e-b9e2-e3a729450132-1Harkness, Karen9dfa0f25-0008-46e9-991e-03ccd8503814-1Grinvalds, Alex38100a2b-7f5f-45a0-a613-3482e10ab354-1McKelvie, Robertb7cfc72e-3a56-4797-8848-d0db71a3ef50-1Bangdiwala, Shrikant I.ad2a4ed9-cbe3-4dad-a2d9-c457ce2309f2-1Yusuf, Salim06a836b5-f5e3-41d9-a516-9cc46e5d7948-1On behalf of the INTER-CHF Investigators.785622bb-52e2-4bc4-b828-729863e5d46b-12019-06-25T17:08:31Z2019-06-25T17:08:31Z2017-07-018 p.Background Most data on mortality and prognostic factors in patients with heart failure come from North America and Europe, with little information from other regions. Here, in the International Congestive Heart Failure (INTERCHF) study, we aimed to measure mortality at 1 year in patients with heart failure in Africa, China, India, the Middle East, southeast Asia and South America; we also explored demographic, clinical, and socioeconomic variables associated with mortality. Methods We enrolled consecutive patients with heart failure (3695 [66%] clinic outpatients, 2105 [34%] hospital in patients) from 108 centres in six geographical regions. We recorded baseline demographic and clinical characteristics and followed up patients at 6 months and 1 year from enrolment to record symptoms, medications, and outcomes. Time to death was studied with Cox proportional hazards models adjusted for demographic and clinical variables, medications, socioeconomic variables, and region. We used the explained risk statistic to calculate the relative contribution of each level of adjustment to the risk of death. Findings We enrolled 5823 patients within 1 year (with 98% follow-up). Overall mortality was 16·5%: highest in Africa (34%) and India (23%), intermediate in southeast Asia (15%), and lowest in China (7%), South America (9%), and the Middle East (9%). Regional differences persisted after multivariable adjustment. Independent predictors of mortality included cardiac variables (New York Heart Association Functional Class III or IV, previous admission for heart failure, and valve disease) and non-cardiac variables (body-mass index, chronic kidney disease, and chronic obstructive pulmonary disease). 46% of mortality risk was explained by multivariable modelling with these variables; however, the remainder was unexplained. Interpretation Marked regional differences in mortality in patients with heart failure persisted after multivariable adjustment for cardiac and non-cardiac factors. Therefore, variations in mortality between regions could be the result of health-care infrastructure, quality and access, or environmental and genetic factors. Further studies in large, global cohorts are needed. Funding The study was supported by Novartis.application/pdf10.1016/S2214-109X(17)30196-12214-109Xhttps://repositorio.udes.edu.co/handle/001/3203engThe Lancet Global HealthDerechos Reservados - Universidad de Santander, 2017info:eu-repo/semantics/closedAccessAtribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)https://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_14cbhttps://www.thelancet.com/action/showPdf?pii=S2214-109X%2817%2930196-1GlobalMortalityHeart failureINTER-CHFGlobal mortality variations in patients with heart failure : Results from the International Congestive Heart Failure (INTER-CHF) prospective cohort studyArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85PublicationTHUMBNAILGlobal mortality variations in patients with heart failure. results from the International Congestive Heart Failure (INTER-CHF) prospective cohort study.pdf.jpgGlobal mortality variations in patients with heart failure. results from the International Congestive Heart Failure (INTER-CHF) prospective cohort study.pdf.jpgGenerated Thumbnailimage/jpeg1947https://repositorio.udes.edu.co/bitstreams/49d9fdf2-9d86-4fb1-b478-5c8378aa67ff/download763d4f5a94ee2f8ab59bc4b09107f378MD54Global mortality variations in patients with heart failure Results from the International Congestive Heart Failure (INTER-CHF) prospective cohort study.pdf.jpgGlobal mortality variations in patients with heart failure Results from the International Congestive Heart Failure (INTER-CHF) prospective cohort study.pdf.jpgGenerated Thumbnailimage/jpeg17792https://repositorio.udes.edu.co/bitstreams/9dcabd76-8097-495e-b73f-9e41222af705/download0f31dcad589ffa75d8051b80b3789e54MD59LICENSElicense.txtlicense.txttext/plain; charset=utf-859https://repositorio.udes.edu.co/bitstreams/c40b2409-3cbe-4cbf-9e16-5e1210b31400/download38d94cf55aa1bf2dac1a736ac45c881cMD52ORIGINALGlobal mortality variations in patients with heart failure Results from the International Congestive Heart Failure (INTER-CHF) prospective cohort study.pdfArtículo Principalapplication/pdf922783https://repositorio.udes.edu.co/bitstreams/bcbb0e66-848a-45da-9f10-b4cb4ec4b143/download492d4c609d9f529358561f9d7119d718MD57TEXTGlobal mortality variations in patients with heart failure. 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