Determinación de Títulos de Anticuerpos Anti-Moquillo en Caninos de Bucaramanga y su Área Metropolitana
Digital
- Autores:
-
Cruz-Barajas, María Camila
- Tipo de recurso:
- Trabajo de grado de pregrado
- Fecha de publicación:
- 2022
- Institución:
- Universidad de Santander
- Repositorio:
- Repositorio Universidad de Santander
- Idioma:
- OAI Identifier:
- oai:repositorio.udes.edu.co:001/8267
- Acceso en línea:
- https://repositorio.udes.edu.co/handle/001/8267
- Palabra clave:
- Transmisión
Estudio epidemiológico
Anticuerpos antivirales
Prevención
Distemper
Transmition
Epidemiological study
Antiviral antibodies
Prevention
Distemper
- Rights
- openAccess
- License
- http://purl.org/coar/access_right/c_abf2
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Determinación de Títulos de Anticuerpos Anti-Moquillo en Caninos de Bucaramanga y su Área Metropolitana |
| dc.title.translated.none.fl_str_mv |
Determination of Antibodies Titers Anti-Distemper in Dogs from Bucaramanga and Metropolitan Area |
| title |
Determinación de Títulos de Anticuerpos Anti-Moquillo en Caninos de Bucaramanga y su Área Metropolitana |
| spellingShingle |
Determinación de Títulos de Anticuerpos Anti-Moquillo en Caninos de Bucaramanga y su Área Metropolitana Transmisión Estudio epidemiológico Anticuerpos antivirales Prevención Distemper Transmition Epidemiological study Antiviral antibodies Prevention Distemper |
| title_short |
Determinación de Títulos de Anticuerpos Anti-Moquillo en Caninos de Bucaramanga y su Área Metropolitana |
| title_full |
Determinación de Títulos de Anticuerpos Anti-Moquillo en Caninos de Bucaramanga y su Área Metropolitana |
| title_fullStr |
Determinación de Títulos de Anticuerpos Anti-Moquillo en Caninos de Bucaramanga y su Área Metropolitana |
| title_full_unstemmed |
Determinación de Títulos de Anticuerpos Anti-Moquillo en Caninos de Bucaramanga y su Área Metropolitana |
| title_sort |
Determinación de Títulos de Anticuerpos Anti-Moquillo en Caninos de Bucaramanga y su Área Metropolitana |
| dc.creator.fl_str_mv |
Cruz-Barajas, María Camila |
| dc.contributor.advisor.none.fl_str_mv |
Goyeneche-Patiño, Diego Andrés |
| dc.contributor.author.none.fl_str_mv |
Cruz-Barajas, María Camila |
| dc.contributor.jury.none.fl_str_mv |
Pinilla-León, Juan Carlos Barrera-Rivera, Jennifer |
| dc.subject.proposal.spa.fl_str_mv |
Transmisión Estudio epidemiológico Anticuerpos antivirales Prevención Distemper |
| topic |
Transmisión Estudio epidemiológico Anticuerpos antivirales Prevención Distemper Transmition Epidemiological study Antiviral antibodies Prevention Distemper |
| dc.subject.proposal.eng.fl_str_mv |
Transmition Epidemiological study Antiviral antibodies Prevention Distemper |
| description |
Digital |
| publishDate |
2022 |
| dc.date.issued.none.fl_str_mv |
2022-12-12 |
| dc.date.accessioned.none.fl_str_mv |
2023-03-31T16:51:12Z |
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2023-03-31T16:51:12Z |
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Trabajo de grado - Pregrado |
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http://purl.org/coar/resource_type/c_7a1f |
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https://repositorio.udes.edu.co/handle/001/8267 |
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T 35.22 C789d |
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https://repositorio.udes.edu.co/handle/001/8267 |
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Álvarez, M. M., Figueredo, E. Á., & Gómez, M. P. (2006). Seroprevalencia de anticuerpos contra Moquillo canino en perros no vacunados en dos municipios de Ciudad de la Habana. REDVET. Revista Electrónica de Veterinaria, VII(9), 1-6. Ayala, R. M. (2018). DISTEMPER CANINO: ESTUDIO RETROSPECTIVO DE PREVALENCIA (2015–2017) EN PACIENTES ATENDIDOS EN EL HOSPITAL VETERINARIO DE PEQUEÑAS ESPECIES DEL IICV-UABC. https://repositorioinstitucional.uabc.mx/bitstream/20.500.12930/2565/1/VET008240.pdf Bergmann, M., Freisl, M., Zablotski, Y., Khan, M. A. A., Speck, S., Truyen, U., & Hartmann, K. (2021). Prevalence of Neutralizing Antibodies to Canine Distemper Virus and Response to Vaccination in Client-Owned Adult Healthy Dogs. Viruses, 13(5), 945. https://doi.org/10.3390/v13050945 Canales K’ana, D. H. (2020). Virus del distemper canino: Revisión actualizada del agente y la patogenia de la enfermedad [Universidad Nacional Mayor de San Marcos]. PDF. https://cybertesis.unmsm.edu.pe/bitstream/handle/20.500.12672/12267/Canales_kd.pdf?s equence=1&isAllowed=y Céspedes, P., Navarro, C., & Alvial, N. (2010). distemper canino: ¿reemergencia o negligencia? 6. Day, M. J., Carey, S., Clercx, C., Kohn, B., MarsilIo, F., Thiry, E., Freyburger, L., Schulz, B., & Walker, D. J. (2020). Aetiology of Canine Infectious Respiratory Disease Complex and Prevalence of its Pathogens in Europe. Journal of Comparative Pathology, 176, 86-108. https://doi.org/10.1016/j.jcpa.2020.02.005 Day, M. J., Crawford, C., Marcondes, M., & Squires, R. A. (s. f.). Recommendations on vaccination for Latin American small animal practitioners: A report of the WSAVA Vaccination Guidelines Group. 2020, 35. Del Puerto, H. L., Vasconcelos, A. C., Moro, L., Alves, F., Braz, G. F., & Martins, A. S. (2010). Canine distemper virus detection in asymptomatic and non vaccinated dogs. Pesquisa Veterinária Brasileira, 30(2), 139-144. https://doi.org/10.1590/S0100- 736X2010000200007 Dorji, T., Tenzin, T., Tenzin, K., Tshering, D., Rinzin, K., Phimpraphai, W., & de Garine- Wichatitsky, M. (2020). Seroprevalence and risk factors of canine distemper virus in the pet and stray dogs in Haa, western Bhutan. BMC Veterinary Research, 16(1), 135. https://doi.org/10.1186/s12917-020-02355-x Duque-Valencia, J., Diaz, F. J., & Ruiz-Saenz, J. (2019). Phylogenomic Analysis of Two Co- Circulating Canine Distemper Virus Lineages in Colombia. Pathogens, 9(1), 26. https://doi.org/10.3390/pathogens9010026 Espinal, M. A., Díaz, F. J., & Ruiz-Saenz, J. (2014). Phylogenetic evidence of a new canine distemper virus lineage among domestic dogs in Colombia, South America. Veterinary Microbiology, 172(1-2), 168-176. https://doi.org/10.1016/j.vetmic.2014.05.019 Feijóo, G., Yamasaki, K., Delucchi, L., & Verdes, J. M. (2021). Central nervous system lesions caused by canine distemper virus in 4 vaccinated dogs. Journal of Veterinary Diagnostic Investigation, 33(4), 640-647. https://doi.org/10.1177/10406387211009210 Fighera, R. A., Souza, T. M., Silva, M. C., Brum, J. S., Graça, D. L., Kommers, G. D., Irigoyen, L. F., & Barros, C. S. L. (2008). Causas de morte e razões para eutanásia de cães da Mesorregião do Centro Ocidental Rio-Grandense (1965-2004). Pesquisa Veterinária Brasileira, 28(4), 223-230. https://doi.org/10.1590/S0100-736X2008000400005 Greene, C. E. (Ed.). (2012). Infectious diseases of the dog and cat (4th ed). Elsevier/Saunders Kapil, S., & Yeary, T. J. (2011). Canine Distemper Spillover in Domestic Dogs from Urban Wildlife. Veterinary Clinics of North America: Small Animal Practice, 41(6), 1069-1086. https://doi.org/10.1016/j.cvsm.2011.08.005 Lechner, E. S., Crawford, P. C., Levy, J. K., Edinboro, C. H., Dubovi, E. J., & Caligiuri, R. (2010). Prevalence of protective antibody titers for canine distemper virus and canine parvovirus in dogs entering a Florida animal shelter. Journal of the American Veterinary Medical Association, 236(12), 1317-1321. https://doi.org/10.2460/javma.236.12.1317 Linares-Villalba, S. E., Correa-Salgado, A. M., & Velásquez-Garzón, L. H. (2010). Diagnóstico de moquillo canino con la prueba Dot-ELISA. Junio 20, 2010, 8. Litster, A., Nichols, J., & Volpe, A. (2012). Prevalence of positive antibody test results for canine parvovirus (CPV) and canine distemper virus (CDV) and response to modified live vaccination against CPV and CDV in dogs entering animal shelters. Veterinary Microbiology, 157(1-2), 86-90. https://doi.org/10.1016/j.vetmic.2011.12.030 Maclachlan, N. J., Dubovi, E. J., Barthold, S. W., Swayne, D. E., & Winton, J. R. (Eds.). (2017). Fenner’s veterinary virology (Fifth edition). Elsevier/AP, Academic Press is an imprint of Elsevier. Mahon, J. L., Rozanski, E. A., & Paul, A. L. (2017). Prevalence of serum antibody titers against canine distemper virus and canine parvovirus in dogs hospitalized in an intensive care unit. Journal of the American Veterinary Medical Association, 250(12), 1413-1418. https://doi.org/10.2460/javma.250.12.1413 Martella, V., Elia, G., & Buonavoglia, C. (2008). Canine Distemper Virus. Veterinary Clinics of North America: Small Animal Practice, 38(4), 787-797. https://doi.org/10.1016/j.cvsm.2008.02.007 Martinez-Gutierrez, M., & Ruiz-Saenz, J. (2016). Diversity of susceptible hosts in canine distemper virus infection: A systematic review and data synthesis. BMC Veterinary Research, 12(1), 78. https://doi.org/10.1186/s12917-016-0702-z McCaw, D. L., Thompson, M., Tate, D., Bonderer, A., & Chen, Y. J. (1998). Serum distemper virus and parvovirus antibody titers among dogs brought to a veterinary hospital for revaccination. Journal of the American Veterinary Medical Association, 213(1), 72-75. Pinotti, M. A. (2011). DISTEMPER CANINO: EVALUACIÓN DE DOS ALTERNATIVAS TERAPÉUTICAS Y CARACTERIZACIÓN DE ASPECTOS CLÍNICOEPIDEMIOLÓGICOS EN LA CIUDAD DE SANTA FE, DURANTE LOS AÑOS 1998— 2009. [Facultad de Ciencias Veterinarias Universidad Nacional del Litoral]. https://bibliotecavirtual.unl.edu.ar:8443/bitstream/handle/11185/323/Tesis%20Distemper %20canino%20evaluaci%c3%b3n%20de%20....pdf?sequence=1&isAllowed=y Rendon-Marin, S., da Fontoura Budaszewski, R., Canal, C. W., & Ruiz-Saenz, J. (2019). Tropism and molecular pathogenesis of canine distemper virus. Virology Journal, 16(1), 30. https://doi.org/10.1186/s12985-019-1136-6 Riascos Gómez, A. F. R. (2019). Prevalencia del virus del Distemper Canino en perros (Canis lupus familiaris) de Risaralda, Colombia. - Buscar con Google. https://www.google.com/search?q=Riascos+G%C3%B3mez%2C+A.+F.+(2019).+Preval encia+del+virus+del+Distemper+Canino+en+perros+(Canis+lupus+familiaris)+de+Risar alda%2C+Colombia.&sourceid=chrome&ie=UTF-8 Taguchi, M., Namikawa, K., Maruo, T., Orito, K., Lynch, J., & Sahara, H. (2011). Antibody titers for canine parvovirus type-2, canine distemper virus, and canine adenovirus type-1 in adult household dogs. The Canadian Veterinary Journal = La Revue Veterinaire Canadienne, 52(9), 983-986. Vila Nova, B., Cunha, E., Sepúlveda, N., Oliveira, M., São Braz, B., Tavares, L., Almeida, V., & Gil, S. (2018). Evaluation of the humoral immune response induced by vaccination for canine distemper and parvovirus: A pilot study. BMC Veterinary Research, 14(1), 348. https://doi.org/10.1186/s12917-018-1673-z Waner, T., Mazar, S., & Keren-Kornblatt, E. (2006). Application of a Dot Enzyme-Linked Immunosorbent Assay for Evaluation of the Immune Status to Canine Parvovirus and Distemper Virus in Adult Dogs before Revaccination. Journal of Veterinary Diagnostic Investigation, 18(3), 267-270. https://doi.org/10.1177/104063870601800306 |
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Universidad de Santander |
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Bucaramanga |
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Facultad de Ciencias Exactas, Naturales y Agropecuarias |
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Bucaramanga, Colombia |
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Medicina Veterinaria |
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Universidad de Santander |
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Universidad de Santander |
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Goyeneche-Patiño, Diego Andrésa8bf4ff9-b599-4e6f-bf50-6e4876780359-1Cruz-Barajas, María Camila1a05a4d1-7046-4b41-9598-f23c4faa3747-1Pinilla-León, Juan Carlosa326a662-2472-455a-9fc3-a9fdb240fa5e-1Barrera-Rivera, Jenniferfe672c30-7e02-4d2d-813d-96c94593f3de-12023-03-31T16:51:12Z2023-03-31T16:51:12Z2022-12-12DigitalEl distemper canino, es una enfermedad viral altamente contagiosa y patogénica debido a sus altas tasas de morbilidad y mortalidad. El virus es del género Morbillivirus y hace parte de la familia Paramyxoviridae. La prevención es realizada por medio de la vacunación, al ser la respuesta inmune individual y especifica no todos los caninos desarrollan títulos de anticuerpos IgM e IgG protectivos, debido a esto, se presentan caninos vacunados con títulos de anticuerpos bajos por una estimulación pobre de la actividad celular, encontrándose expuestos a contraer la enfermedad. La falla vacunal se debe a una respuesta inmune insuficiente, el estatus sanitario del animal y a un mal manejo vacunal. Debido a esto el objetivo principal de este trabajo es determinar los títulos de anticuerpos anti-moquillo en caninos de Bucaramanga y su área metropolitana. Se tomaron muestras de sangre de 92 caninos mayores a 6 meses de edad con antecedentes de vacunación contra moquillo. Y posteriormente mediante la técnica de inmunoensayo enzimático indirecto (ELISA), se determinaron los títulos de anticuerpos IgG e IgM contra al virus en suero. Adicionalmente se realizó una encuesta epidemiológica a los propietarios, con el fin de caracterizar variables poblacionales y su posible relación con los títulos de anticuerpos obtenidos. Se determinó que, de los 92 caninos implementados en el estudio, 28/92 presentaron títulos de anticuerpos IgG altos (31%), 55/92 presentaron títulos de anticuerpos IgG medios (60%) y 9/92 presentaron títulos de anticuerpos IgG bajos (9%) con una asociación estadística significativa con las variables poblacionales edad y refuerzo de vacunación. Los títulos de anticuerpos IgM fueron clasificados en bajos/medios y altos, con un total de 79/92 caninos con títulos de anticuerpos IgM altos (86%) y 13/92 caninos con títulos de anticuerpos IgM medios/ bajos (14%), la clasificación no tuvo asociación estadística con las variablesCanine distemper is a highly contagious and pathogenic viral disease, due to its high morbidity and mortality rates. The virus belongs to the Morbillivirus genus and Paramyxoviridae family. Prevention is based on vaccination, since the immune response is individual and specific, not all dogs develop protective IgM and IgG antibody titers, due to this, vaccinated dogs present low antibody titers explained by poor stimulation of celular immunity and are exposed to contracting the disease. Vaccine failure is the result of insufficient immune response, animal health status and poor vaccination management. Therefore, the aim of this work is to determine the titers of anti-distemper antibodies (IgG and IgM) in dogs from Bucaramanga and its metropolitan area. Blood from of 92 dogs older than 6 months of age with a history of vaccination against distemper was taken. After serum extraction samples were analyzed using indirect enzyme immunoassay (ELISA) technique. Additionally, an epidemiological survey was carried out to the owners, in order to characterize population variables and their possible relationship with the antibody titers obtained. that the results showed that, out of the 92 canines implemented in the study, 28/92 presented high IgG antibody titers (30.43%), 55/92 presented medium IgG antibody titers (59.78%) and 9/92 presented titers of low IgG antibodies (9.78%) with a significant statistical association in the population variables age and vaccination reinforcement. IgM antibody titers were classified as low/medium and high, with a total of 79/92 canines with high IgM antibody titers (85.86%) and 13/92 canines with medium/low IgM antibody titers (14, 13%) without significant statistical association.PregradoMédico VeterinarioIntroducción .................................................................................................................................. 13 Planteamiento del Problema ......................................................................................................... 20 Descripción del Problema ............................................................................................................. 20 Pregunta de Investigación ............................................................................................................. 23 Justificación .................................................................................................................................. 24 Objetivos ....................................................................................................................................... 26 Objetivo General ........................................................................................................................... 26 Objetivos Específicos.................................................................................................................... 26 Metodología .................................................................................................................................. 27 Tipo de Estudio ............................................................................................................................. 27 Población y Muestra ..................................................................................................................... 27 Determinación Títulos de Anticuerpos Anti-Moquillo IgG.......................................................... 28 Determinación Títulos de Anticuerpos Anti-Moquillo IgM ......................................................... 29 Análisis Estadístico ....................................................................................................................... 30 Análisis Para la Determinación de Títulos de Anticuerpos IgG .................................................. 30 Análisis Para la Determinación de Títulos de Anticuerpos IgM .................................................. 31 Análisis Estadístico Para la Determinación de Asociaciones ...................................................... 31 Consideraciones Éticas ................................................................................................................. 31 Resultados ..................................................................................................................................... 34 Descripción Poblacional de los Caninos Muestreados ................................................................. 34 Determinación de Anticuerpos por IgG ........................................................................................ 35 Determinación de Anticuerpos por IgM ....................................................................................... 36 Asociación de Variables Poblacionales con Títulos de Anticuerpos IgG ..................................... 37 Asociación de Variables Poblacionales con Títulos de Anticuerpos IgM .................................... 41 Discusión....................................................................................................................................... 45 Conclusiones ................................................................................................................................. 50 Referencias Bibliográficas ............................................................................................................ 51 Apéndices ...................................................................................................................................... 5665 Papplication/pdfT 35.22 C789dhttps://repositorio.udes.edu.co/handle/001/8267Universidad de SantanderBucaramangaFacultad de Ciencias Exactas, Naturales y AgropecuariasBucaramanga, ColombiaMedicina VeterinariaÁlvarez, M. M., Figueredo, E. Á., & Gómez, M. P. (2006). Seroprevalencia de anticuerpos contra Moquillo canino en perros no vacunados en dos municipios de Ciudad de la Habana. REDVET. Revista Electrónica de Veterinaria, VII(9), 1-6.Ayala, R. M. (2018). DISTEMPER CANINO: ESTUDIO RETROSPECTIVO DE PREVALENCIA (2015–2017) EN PACIENTES ATENDIDOS EN EL HOSPITAL VETERINARIO DE PEQUEÑAS ESPECIES DEL IICV-UABC. https://repositorioinstitucional.uabc.mx/bitstream/20.500.12930/2565/1/VET008240.pdfBergmann, M., Freisl, M., Zablotski, Y., Khan, M. A. A., Speck, S., Truyen, U., & Hartmann, K. (2021). Prevalence of Neutralizing Antibodies to Canine Distemper Virus and Response to Vaccination in Client-Owned Adult Healthy Dogs. Viruses, 13(5), 945. https://doi.org/10.3390/v13050945Canales K’ana, D. H. (2020). Virus del distemper canino: Revisión actualizada del agente y la patogenia de la enfermedad [Universidad Nacional Mayor de San Marcos]. PDF. https://cybertesis.unmsm.edu.pe/bitstream/handle/20.500.12672/12267/Canales_kd.pdf?s equence=1&isAllowed=yCéspedes, P., Navarro, C., & Alvial, N. (2010). distemper canino: ¿reemergencia o negligencia? 6.Day, M. J., Carey, S., Clercx, C., Kohn, B., MarsilIo, F., Thiry, E., Freyburger, L., Schulz, B., & Walker, D. J. (2020). Aetiology of Canine Infectious Respiratory Disease Complex and Prevalence of its Pathogens in Europe. Journal of Comparative Pathology, 176, 86-108. https://doi.org/10.1016/j.jcpa.2020.02.005Day, M. J., Crawford, C., Marcondes, M., & Squires, R. A. (s. f.). Recommendations on vaccination for Latin American small animal practitioners: A report of the WSAVA Vaccination Guidelines Group. 2020, 35.Del Puerto, H. L., Vasconcelos, A. C., Moro, L., Alves, F., Braz, G. F., & Martins, A. S. (2010). Canine distemper virus detection in asymptomatic and non vaccinated dogs. 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DISTEMPER CANINO: EVALUACIÓN DE DOS ALTERNATIVAS TERAPÉUTICAS Y CARACTERIZACIÓN DE ASPECTOS CLÍNICOEPIDEMIOLÓGICOS EN LA CIUDAD DE SANTA FE, DURANTE LOS AÑOS 1998— 2009. [Facultad de Ciencias Veterinarias Universidad Nacional del Litoral]. https://bibliotecavirtual.unl.edu.ar:8443/bitstream/handle/11185/323/Tesis%20Distemper %20canino%20evaluaci%c3%b3n%20de%20....pdf?sequence=1&isAllowed=yRendon-Marin, S., da Fontoura Budaszewski, R., Canal, C. W., & Ruiz-Saenz, J. (2019). Tropism and molecular pathogenesis of canine distemper virus. Virology Journal, 16(1), 30. https://doi.org/10.1186/s12985-019-1136-6Riascos Gómez, A. F. R. (2019). Prevalencia del virus del Distemper Canino en perros (Canis lupus familiaris) de Risaralda, Colombia. - Buscar con Google. https://www.google.com/search?q=Riascos+G%C3%B3mez%2C+A.+F.+(2019).+Preval encia+del+virus+del+Distemper+Canino+en+perros+(Canis+lupus+familiaris)+de+Risar alda%2C+Colombia.&sourceid=chrome&ie=UTF-8Taguchi, M., Namikawa, K., Maruo, T., Orito, K., Lynch, J., & Sahara, H. (2011). Antibody titers for canine parvovirus type-2, canine distemper virus, and canine adenovirus type-1 in adult household dogs. The Canadian Veterinary Journal = La Revue Veterinaire Canadienne, 52(9), 983-986.Vila Nova, B., Cunha, E., Sepúlveda, N., Oliveira, M., São Braz, B., Tavares, L., Almeida, V., & Gil, S. (2018). Evaluation of the humoral immune response induced by vaccination for canine distemper and parvovirus: A pilot study. BMC Veterinary Research, 14(1), 348. https://doi.org/10.1186/s12917-018-1673-zWaner, T., Mazar, S., & Keren-Kornblatt, E. (2006). Application of a Dot Enzyme-Linked Immunosorbent Assay for Evaluation of the Immune Status to Canine Parvovirus and Distemper Virus in Adult Dogs before Revaccination. Journal of Veterinary Diagnostic Investigation, 18(3), 267-270. https://doi.org/10.1177/104063870601800306Derechos Reservados - Universidad de Santander, 2022. 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