Obesity and Preeclampsia. Common Pathophysiological Mechanisms
Digital
- Autores:
-
Lopez-Jaramillo, Patricio
Barajas, Juan
Rueda-Quijano, Sandra M.
Lopez-Lopez, Cristina
Felix, Camilo
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2018
- Institución:
- Universidad de Santander
- Repositorio:
- Repositorio Universidad de Santander
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.udes.edu.co:001/6094
- Acceso en línea:
- https://repositorio.udes.edu.co/handle/001/6094
- Palabra clave:
- Preeclampsia
Obesity
Endothelial dysfunction
Nitric oxide
Cardiovascular risk
- Rights
- openAccess
- License
- © 2018 Lopez-Jaramillo, Barajas, Rueda-Quijano, Lopez-Lopez and Felix.
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Obesity and Preeclampsia. Common Pathophysiological Mechanisms |
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Obesity and Preeclampsia. Common Pathophysiological Mechanisms |
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Obesity and Preeclampsia. Common Pathophysiological Mechanisms Preeclampsia Obesity Endothelial dysfunction Nitric oxide Cardiovascular risk |
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Obesity and Preeclampsia. Common Pathophysiological Mechanisms |
| title_full |
Obesity and Preeclampsia. Common Pathophysiological Mechanisms |
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Obesity and Preeclampsia. Common Pathophysiological Mechanisms |
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Obesity and Preeclampsia. Common Pathophysiological Mechanisms |
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Obesity and Preeclampsia. Common Pathophysiological Mechanisms |
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Lopez-Jaramillo, Patricio Barajas, Juan Rueda-Quijano, Sandra M. Lopez-Lopez, Cristina Felix, Camilo |
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Lopez-Jaramillo, Patricio Barajas, Juan Rueda-Quijano, Sandra M. Lopez-Lopez, Cristina Felix, Camilo |
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Masira |
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Preeclampsia Obesity Endothelial dysfunction Nitric oxide Cardiovascular risk |
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Preeclampsia Obesity Endothelial dysfunction Nitric oxide Cardiovascular risk |
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Digital |
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2018 |
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2018-12-19 |
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Lopez-Jaramillo P, Barajas J, Rueda-Quijano SM, Lopez-Lopez C and Felix C (2018) Obesity and Preeclampsia: Common Pathophysiological Mechanisms. Front. Physiol. 9:1838. doi: 10.3389/fphys.2018.01838 |
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Scopus |
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Frontiers in Physiology |
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© 2018 Lopez-Jaramillo, Barajas, Rueda-Quijano, Lopez-Lopez and Felix. |
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© 2018 Lopez-Jaramillo, Barajas, Rueda-Quijano, Lopez-Lopez and Felix. Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0) https://creativecommons.org/licenses/by-nc/4.0/ http://purl.org/coar/access_right/c_abf2 |
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10 p |
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Frontiers in Physiology |
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Lopez-Jaramillo, Patricio9a71267b-dcb0-4d31-b37d-2d30be58d4d2-1Barajas, Juan012cb90d-c8a6-4459-8861-4b887a80f17a-1Rueda-Quijano, Sandra M.3e648484-f757-44d1-aca5-beb667dcf67f-1Lopez-Lopez, Cristina73e4a5e7-826e-4256-8f9e-7328ea498a7e-1Felix, Camilo8f963374-f605-4ca6-8884-7cdaa10d0c3e-1Masira2022-02-22T13:26:03Z2022-02-22T13:26:03Z2018-12-19DigitalPreeclampsia is a disorder specific of the human being that appears after 20 weeks of pregnancy, characterized by new onset of hypertension and proteinuria. Abnormal placentation and reduced placental perfusion associated to impaired trophoblast invasion and alteration in the compliance of uterine spiral arteries are the early pathological findings that are present before the clinical manifestations of preeclampsia. Later on, the endothelial and vascular dysfunction responsible of the characteristic vasoconstriction of preeclampsia appear. Different nutritional risk factors such as a maternal deficit in the intake of calcium, protein, vitamins and essential fatty acids, have been shown to play a role in the genesis of preeclampsia, but also an excess of weight gain during pregnancy or a pre-pregnancy state of obesity and overweight, which are associated to hyperinsulinism, insulin resistance and maternal systemic inflammation, are proposed as one of the mechanism that conduce to endothelial dysfunction, hypertension, proteinuria, thrombotic responses, multi-organ damage, and high maternal mortality and morbidity. Moreover, it has been demonstrated that pregnant women that suffer preeclampsia will have an increased risk of future cardiovascular disease and related mortality in their later life. In this article we will discuss the results of studies performed in different populations that have shown an interrelationship between obesity and overweight with the presence of preeclampsia. Moreover, we will review some of the common mechanisms that explain this interrelationship, particularly the alterations in the L-arginine/nitric oxide pathway as a crucial mechanism that is common to obesity, preeclampsia and cardiovascular diseases.Ciencias Médicas y de la Salud10 papplication/pdf10.3389/fphys.2018.01838https://repositorio.udes.edu.co/handle/001/6094engFrontiers in PhysiologyUSA1019Lopez-Jaramillo P, Barajas J, Rueda-Quijano SM, Lopez-Lopez C and Felix C (2018) Obesity and Preeclampsia: Common Pathophysiological Mechanisms. Front. Physiol. 9:1838. doi: 10.3389/fphys.2018.01838ScopusFrontiers in Physiology© 2018 Lopez-Jaramillo, Barajas, Rueda-Quijano, Lopez-Lopez and Felix.info:eu-repo/semantics/openAccessAtribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)https://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2https://www.frontiersin.org/articles/10.3389/fphys.2018.01838/fullPreeclampsiaObesityEndothelial dysfunctionNitric oxideCardiovascular riskObesity and Preeclampsia. Common Pathophysiological MechanismsArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85Todas las AudienciasPublicationORIGINALObesity and Preeclampsia. Common Pathophysiological Mechanisms.pdfObesity and Preeclampsia. Common Pathophysiological Mechanisms.pdfapplication/pdf226183https://repositorio.udes.edu.co/bitstreams/07b12d82-3233-4cd1-943b-3feb5327919d/download65d6ee1d6a48a7e2ab864e57146573c1MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-859https://repositorio.udes.edu.co/bitstreams/dad30eb7-44cf-46a2-85f0-fa0d537ca46b/download38d94cf55aa1bf2dac1a736ac45c881cMD52TEXTObesity and Preeclampsia. Common Pathophysiological Mechanisms.pdf.txtObesity and Preeclampsia. Common Pathophysiological Mechanisms.pdf.txtExtracted texttext/plain5https://repositorio.udes.edu.co/bitstreams/94579ff9-cec8-4366-967d-095f5e50b34e/download5dbe86c1111d64f45ba435df98fdc825MD53THUMBNAILObesity and Preeclampsia. Common Pathophysiological Mechanisms.pdf.jpgObesity and Preeclampsia. Common Pathophysiological Mechanisms.pdf.jpgGenerated Thumbnailimage/jpeg10837https://repositorio.udes.edu.co/bitstreams/ca3c9f6d-4f4b-48a5-9c11-4cc17f76b83f/download2355a53cd088183ac6a1e168d016a543MD54001/6094oai:repositorio.udes.edu.co:001/60942023-10-09 18:07:01.288https://creativecommons.org/licenses/by-nc/4.0/© 2018 Lopez-Jaramillo, Barajas, Rueda-Quijano, Lopez-Lopez and Felix.https://repositorio.udes.edu.coRepositorio Universidad de Santandersoporte@metabiblioteca.comTGljZW5jaWEgZGUgUHVibGljYWNpw7NuIFVERVMKRGlyZWN0cmljZXMgZGUgVVNPIHkgQUNDRVNPCgo= |