First colombian multicentric newborn screening for congenital toxoplasmosis

10 p.

Autores:
Gómez Marin, Jorge Enrique
De la Torre, Alejandra
Angel Muller, Edith
Rubio, Jorge
Arenas, Jaime
Osorio, Elkin
Nuñez, Lilian
Pinzón, Lyda
Mendez Cordoba, Luis Carlos
Bustos, Agustin
De la Hoz, Isabel
Silva, Pedro Ignacio
Beltrán, Monica
Chacón, Leonor
Marrugo, Martha
Manjarres, Cristina
Baquero, Hernando
Lora, Fabiana
Torres Rivas, Elizabeth
Zuluaga, Oscar Elias
Estrada, Monica
Moscote, Lacides
Silva, Myriam Teresa
Rivera, Raul
Molina, Angie
Najera, Shirley
Sanabria, Antonio
Ramírez, Maria Luisa
Alarcon, Claudia
Restrepo, Natalia
Falla, Alejandra
Rodríguez, Tailandia
Castaño, Giovanny
Tipo de recurso:
Article of journal
Fecha de publicación:
2011
Institución:
Universidad de Santander
Repositorio:
Repositorio Universidad de Santander
Idioma:
eng
OAI Identifier:
oai:repositorio.udes.edu.co:001/3285
Acceso en línea:
https://repositorio.udes.edu.co/handle/001/3285
Palabra clave:
Congenital toxoplasmosis
Toxoplasmosis congénita
Rights
openAccess
License
Derechos Reservados - PLoS Neglected Tropical Diseases, 2011
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dc.title.eng.fl_str_mv First colombian multicentric newborn screening for congenital toxoplasmosis
title First colombian multicentric newborn screening for congenital toxoplasmosis
spellingShingle First colombian multicentric newborn screening for congenital toxoplasmosis
Congenital toxoplasmosis
Toxoplasmosis congénita
title_short First colombian multicentric newborn screening for congenital toxoplasmosis
title_full First colombian multicentric newborn screening for congenital toxoplasmosis
title_fullStr First colombian multicentric newborn screening for congenital toxoplasmosis
title_full_unstemmed First colombian multicentric newborn screening for congenital toxoplasmosis
title_sort First colombian multicentric newborn screening for congenital toxoplasmosis
dc.creator.fl_str_mv Gómez Marin, Jorge Enrique
De la Torre, Alejandra
Angel Muller, Edith
Rubio, Jorge
Arenas, Jaime
Osorio, Elkin
Nuñez, Lilian
Pinzón, Lyda
Mendez Cordoba, Luis Carlos
Bustos, Agustin
De la Hoz, Isabel
Silva, Pedro Ignacio
Beltrán, Monica
Chacón, Leonor
Marrugo, Martha
Manjarres, Cristina
Baquero, Hernando
Lora, Fabiana
Torres Rivas, Elizabeth
Zuluaga, Oscar Elias
Estrada, Monica
Moscote, Lacides
Silva, Myriam Teresa
Rivera, Raul
Molina, Angie
Najera, Shirley
Sanabria, Antonio
Ramírez, Maria Luisa
Alarcon, Claudia
Restrepo, Natalia
Falla, Alejandra
Rodríguez, Tailandia
Castaño, Giovanny
dc.contributor.author.spa.fl_str_mv Gómez Marin, Jorge Enrique
De la Torre, Alejandra
Angel Muller, Edith
Rubio, Jorge
Arenas, Jaime
Osorio, Elkin
Nuñez, Lilian
Pinzón, Lyda
Mendez Cordoba, Luis Carlos
Bustos, Agustin
De la Hoz, Isabel
Silva, Pedro Ignacio
Beltrán, Monica
Chacón, Leonor
Marrugo, Martha
Manjarres, Cristina
Baquero, Hernando
Lora, Fabiana
Torres Rivas, Elizabeth
Zuluaga, Oscar Elias
Estrada, Monica
Moscote, Lacides
Silva, Myriam Teresa
Rivera, Raul
Molina, Angie
Najera, Shirley
Sanabria, Antonio
Ramírez, Maria Luisa
Alarcon, Claudia
Restrepo, Natalia
Falla, Alejandra
Rodríguez, Tailandia
Castaño, Giovanny
dc.subject.proposal.eng.fl_str_mv Congenital toxoplasmosis
topic Congenital toxoplasmosis
Toxoplasmosis congénita
dc.subject.proposal.spa.fl_str_mv Toxoplasmosis congénita
description 10 p.
publishDate 2011
dc.date.issued.spa.fl_str_mv 2011-07-01
dc.date.accessioned.spa.fl_str_mv 2019-07-06T17:04:39Z
dc.date.available.spa.fl_str_mv 2019-07-06T17:04:39Z
dc.type.spa.fl_str_mv Artículo de revista
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dc.identifier.doi.spa.fl_str_mv 10.1371/journal.pntd.0001195
dc.identifier.issn.spa.fl_str_mv 1935-2735
1935-2727
dc.identifier.uri.spa.fl_str_mv https://repositorio.udes.edu.co/handle/001/3285
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1935-2735
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url https://repositorio.udes.edu.co/handle/001/3285
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.ispartof.eng.fl_str_mv PLoS Neglected Tropical Diseases
dc.rights.spa.fl_str_mv Derechos Reservados - PLoS Neglected Tropical Diseases, 2011
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dc.rights.creativecommons.spa.fl_str_mv Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)
dc.rights.uri.spa.fl_str_mv https://creativecommons.org/licenses/by-nc/4.0/
rights_invalid_str_mv Derechos Reservados - PLoS Neglected Tropical Diseases, 2011
Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)
https://creativecommons.org/licenses/by-nc/4.0/
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institution Universidad de Santander
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spelling Gómez Marin, Jorge Enrique7beb87e4-66f2-4ed5-b221-8123f3c2ced6-1De la Torre, Alejandrac6c30f30-5e11-4838-80b1-c78ad78431d2-1Angel Muller, Edith85f9f5b4-72c2-4824-8e94-4b56a1a3d14d-1Rubio, Jorge1ccf92f4-5fa1-49b8-80b8-49a15fb505c5-1Arenas, Jaime143fdf0d-d3bc-4174-b761-625d44187049-1Osorio, Elkinda2e2518-7b80-45f9-ac1d-023f051d22ad-1Nuñez, Lilianf9eede73-dff4-437e-836b-a771edc7dbea-1Pinzón, Lyda21271741-0dab-4a69-9d02-341f15b24022-1Mendez Cordoba, Luis Carlos28aa29de-c34e-4961-81d3-e12e72a192f5-1Bustos, Agustin159bc40a-7f02-4604-86a4-eb5b14a8748f-1De la Hoz, Isabel47590f9e-c477-47b5-b635-b0e5f5071350-1Silva, Pedro Ignaciob16826b8-632f-47bd-87fd-28a400beb6a6-1Beltrán, Monicaefdc2a89-5c2c-450c-b388-ab8113285b36-1Chacón, Leonor6249a7e5-c599-45d6-b30c-e0f74e66f57d-1Marrugo, Martha9a95612c-e16e-4b23-ac37-3d14641e7ace-1Manjarres, Cristina3be809c5-2de4-48fd-996b-5c621672207c-1Baquero, Hernando1247f4df-f0a4-4869-8fde-ea84449442ca-1Lora, Fabiana1faac9f7-f356-4f7e-9025-745ffcc12fa8-1Torres Rivas, Elizabethec2e02f7-ccc0-461b-ba49-5c1cfa894306-1Zuluaga, Oscar Elias99b1e082-7b63-4fc8-aa5e-5d7c8ebd9f02-1Estrada, Monica447e245f-2117-4d37-ac19-4272d8838d4e-1Moscote, Lacidesa4f83938-9bde-4c62-b44c-23812523e1b3-1Silva, Myriam Teresafdd2125c-1b2a-4957-b6d6-27404f4e433d-1Rivera, Raul6eac7f3e-977a-475d-ada5-ffcb52f07333-1Molina, Angie0d3f788a-d3d0-4eb7-9a9c-9dee074f10b6-1Najera, Shirleyb9c36e3c-053c-4fd1-8cf7-13b721ecad69-1Sanabria, Antonioc072adf8-0a0d-4d81-bdf1-16591d065a5d-1Ramírez, Maria Luisaae771737-709c-4d51-86bf-450f2c682110-1Alarcon, Claudia1024f308-8751-452d-adc0-b395227e56af-1Restrepo, Nataliaf7637432-60d0-4303-ad19-0013ee1f055b-1Falla, Alejandra10e4d6a6-ffde-4c15-a966-c8fdab56b013-1Rodríguez, Tailandia688182f0-51ca-482a-a9ba-327a926af82c-1Castaño, Giovanny5b665ec1-f7bb-4bed-8c9c-99222c9f8f4e-12019-07-06T17:04:39Z2019-07-06T17:04:39Z2011-07-0110 p.Aims: To determine the incidence of congenital toxoplasmosis in Colombian newborns from 19 hospital or maternal child health services from seven different cities of five natural geographic regions (Caribbean, Central, Andean, Amazonia and Eastern). Materials and Methods: We collected 15,333 samples from umbilical cord blood between the period of March 2009 to May 2010 in 19 different hospitals and maternal-child health services from seven different cities. We applied an IgM ELISA assay (Vircell, Spain) to determine the frequency of IgM anti Toxoplasma. The results in blood cord samples were confirmed either by western blot and repeated ELISA IgM assay. In a sub-sample of 1,613 children that were negative by the anti-Toxoplasma IgM assay, the frequency of specific anti-Toxoplasma IgA by the ISAGA assay was determined. All children with positive samples by IgM, IgA, clinical diagnosis or treatment during pregnancy were recalled for confirmatory tests after day 10 of life. Results: 61 positive samples for specific IgM (0.39%) and 9 positives for IgA (0.5%) were found. 143 questionnaires were positive for a clinical diagnosis or treatment for toxoplasmosis during pregnancy. 109 out of the 218 children that had some of the criteria for postnatal confirmatory tests were followed. Congenital toxoplasmosis infection was confirmed in 15 children: 7 were symptomatic, and three of them died before the first month of life (20% of lethality). A significant correlation was found between a high incidence of markers for congenital toxoplasmosis and higher mean annual rainfall for the city. Conclusions: Incidence for congenital toxoplasmosis is significantly different between hospitals or maternal child health services from different cities in Colombia. Mean annual rainfall was correlated with incidence of congenital toxoplasmosis.application/pdf10.1371/journal.pntd.00011951935-27351935-2727https://repositorio.udes.edu.co/handle/001/3285engPLoS Neglected Tropical DiseasesDerechos Reservados - PLoS Neglected Tropical Diseases, 2011info:eu-repo/semantics/openAccessAtribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)https://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2https://journals.plos.org/plosntds/article/file?id=10.1371/journal.pntd.0001195&type=printableCongenital toxoplasmosisToxoplasmosis congénitaFirst colombian multicentric newborn screening for congenital toxoplasmosisArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85PublicationTHUMBNAILFirst colombian multicentric newborn screening for congenital toxoplasmosis.pdf.jpgFirst colombian multicentric newborn screening for congenital toxoplasmosis.pdf.jpgGenerated Thumbnailimage/jpeg1951https://repositorio.udes.edu.co/bitstreams/e1dde08b-b8fa-493b-bf43-0b4df7463042/downloadcb6b584ad1f296fef18c3eb2611099f9MD54LICENSElicense.txtlicense.txttext/plain; charset=utf-859https://repositorio.udes.edu.co/bitstreams/79e3fdf0-64ba-41b0-ae52-fac70074d466/download38d94cf55aa1bf2dac1a736ac45c881cMD52ORIGINALFirst colombian multicentric newborn screening for congenital toxoplasmosis.pdfArtículo Principalapplication/pdf522722https://repositorio.udes.edu.co/bitstreams/b4121e77-5f83-46e3-a6cd-efbb6898b2dd/downloada3459fc6ea31290c10b090144c43ad36MD55TEXTFirst colombian multicentric newborn screening for congenital toxoplasmosis.pdf.txtFirst colombian multicentric newborn screening for congenital toxoplasmosis.pdf.txtExtracted texttext/plain52534https://repositorio.udes.edu.co/bitstreams/984a2219-3b62-4117-ab4a-e376d8c7a4fe/download32aea095980762f5b937ac0e9bdd581dMD53001/3285oai:repositorio.udes.edu.co:001/32852023-10-10 08:54:41.66https://creativecommons.org/licenses/by-nc/4.0/Derechos Reservados - PLoS Neglected Tropical Diseases, 2011https://repositorio.udes.edu.coRepositorio Universidad de Santandersoporte@metabiblioteca.comTGljZW5jaWEgZGUgUHVibGljYWNpw7NuIFVERVMKRGlyZWN0cmljZXMgZGUgVVNPIHkgQUNDRVNPCgo=