Health-related quality of life and mortality in heart failure. The global congestive heart failure study of 23000 patients from 40 countries
Digital
- Autores:
-
Johansson, Isabelle
Joseph, Philip
Balasubramanian, Kumar
McMurray, John J.V.
Lund, Lars H.
Ezekowitz, Justin A.
Kamath, Deepak
Alhabib, Khalid
Bayes-Genis, Antoni
Budaj, Andrzej
Dans, Antonio
Dzudie, Anastase
Probstfield, Jefferey L.
Fox, Keith A.
Karaye, Kamilu M.
Makubi, Abel
Fukakusa, Bianca
Teo, Koon
Temizhan, Ahmet
Wittlinger, Thomas
Maggioni, Aldo P.
Lanas, Fernando
Lopez-Jaramillo, Patricio
Silva-Cardoso, José
Sliwa, Karen
Dokainish, Hisham
Grinvalds, Alex
McCready, Tara
Yusuf, Salim
G-CHF Investigators
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2021
- Institución:
- Universidad de Santander
- Repositorio:
- Repositorio Universidad de Santander
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.udes.edu.co:001/6046
- Acceso en línea:
- https://doi.org/10.1161/CIRCULATIONAHA.120.050850
https://repositorio.udes.edu.co/handle/001/6046
- Palabra clave:
- Rights
- openAccess
- License
- © 2021 American Heart Association, Inc.
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Health-related quality of life and mortality in heart failure. The global congestive heart failure study of 23000 patients from 40 countries |
| title |
Health-related quality of life and mortality in heart failure. The global congestive heart failure study of 23000 patients from 40 countries |
| spellingShingle |
Health-related quality of life and mortality in heart failure. The global congestive heart failure study of 23000 patients from 40 countries |
| title_short |
Health-related quality of life and mortality in heart failure. The global congestive heart failure study of 23000 patients from 40 countries |
| title_full |
Health-related quality of life and mortality in heart failure. The global congestive heart failure study of 23000 patients from 40 countries |
| title_fullStr |
Health-related quality of life and mortality in heart failure. The global congestive heart failure study of 23000 patients from 40 countries |
| title_full_unstemmed |
Health-related quality of life and mortality in heart failure. The global congestive heart failure study of 23000 patients from 40 countries |
| title_sort |
Health-related quality of life and mortality in heart failure. The global congestive heart failure study of 23000 patients from 40 countries |
| dc.creator.fl_str_mv |
Johansson, Isabelle Joseph, Philip Balasubramanian, Kumar McMurray, John J.V. Lund, Lars H. Ezekowitz, Justin A. Kamath, Deepak Alhabib, Khalid Bayes-Genis, Antoni Budaj, Andrzej Dans, Antonio Dzudie, Anastase Probstfield, Jefferey L. Fox, Keith A. Karaye, Kamilu M. Makubi, Abel Fukakusa, Bianca Teo, Koon Temizhan, Ahmet Wittlinger, Thomas Maggioni, Aldo P. Lanas, Fernando Lopez-Jaramillo, Patricio Silva-Cardoso, José Sliwa, Karen Dokainish, Hisham Grinvalds, Alex McCready, Tara Yusuf, Salim G-CHF Investigators |
| dc.contributor.author.none.fl_str_mv |
Johansson, Isabelle Joseph, Philip Balasubramanian, Kumar McMurray, John J.V. Lund, Lars H. Ezekowitz, Justin A. Kamath, Deepak Alhabib, Khalid Bayes-Genis, Antoni Budaj, Andrzej Dans, Antonio Dzudie, Anastase Probstfield, Jefferey L. Fox, Keith A. Karaye, Kamilu M. Makubi, Abel Fukakusa, Bianca Teo, Koon Temizhan, Ahmet Wittlinger, Thomas Maggioni, Aldo P. Lanas, Fernando Lopez-Jaramillo, Patricio Silva-Cardoso, José Sliwa, Karen Dokainish, Hisham Grinvalds, Alex McCready, Tara Yusuf, Salim G-CHF Investigators |
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Masira |
| description |
Digital |
| publishDate |
2021 |
| dc.date.issued.none.fl_str_mv |
2021-04-28 |
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2022-02-18T14:34:04Z |
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2022-02-18T14:34:04Z |
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Artículo de revista |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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http://purl.org/coar/resource_type/c_6501 |
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Text |
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https://doi.org/10.1161/CIRCULATIONAHA.120.050850 |
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https://repositorio.udes.edu.co/handle/001/6046 |
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https://doi.org/10.1161/CIRCULATIONAHA.120.050850 https://repositorio.udes.edu.co/handle/001/6046 |
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eng |
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eng |
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1242 |
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22 |
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2129 |
| dc.relation.citationvolume.spa.fl_str_mv |
143 |
| dc.relation.indexed.spa.fl_str_mv |
Scopus |
| dc.relation.ispartofjournal.spa.fl_str_mv |
Circulation |
| dc.rights.spa.fl_str_mv |
© 2021 American Heart Association, Inc. |
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http://purl.org/coar/access_right/c_abf2 |
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info:eu-repo/semantics/openAccess |
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Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0) |
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https://creativecommons.org/licenses/by-nc/4.0/ |
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© 2021 American Heart Association, Inc. Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0) https://creativecommons.org/licenses/by-nc/4.0/ http://purl.org/coar/access_right/c_abf2 |
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openAccess |
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14 p |
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application/pdf |
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American Heart Association, Inc. |
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USA |
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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.120.050850 |
| institution |
Universidad de Santander |
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Johansson, Isabelle84ebb364-bde7-4472-8232-e826f0e0ea1e-1Joseph, Philip35ddb523-bb0e-4c55-9a59-b24968824fbf-1Balasubramanian, Kumar0a03c747-a4c9-4824-9135-7afdf7a9b352-1McMurray, John J.V.d556aafb-250f-46db-b406-53b2195fa530-1Lund, Lars H.26478ad9-5eae-4db8-81ea-44cced6e3c22-1Ezekowitz, Justin A.ded7a635-e4c5-453c-8e99-72d27c92fb4b-1Kamath, Deepak39760db6-d6e5-4092-ab02-1ed73a2cb674-1Alhabib, Khaliddd6c418b-47a5-4e51-be4a-e75b5d9cd1dc-1Bayes-Genis, Antoni85326e26-1094-46f7-9764-08882d4b6ec4-1Budaj, Andrzejf433dc34-6849-4a14-8435-bf8f741e805f-1Dans, Antoniof365ef5a-7610-4022-8485-31d6d3879cd6-1Dzudie, Anastaseb3ba3ad4-e358-4a30-86f9-ff20851fec3a-1Probstfield, Jefferey L.0db6304b-3bdf-4328-aa62-02591dc0017f-1Fox, Keith A.346a05ff-d114-4673-bafe-56302d12a6c3-1Karaye, Kamilu M.f0df167d-4e88-4030-af72-88ececf0321b-1Makubi, Abelba589793-b7ac-4c01-8edc-5383298ae048-1Fukakusa, Bianca768ff8a3-c47a-4af9-9928-28a6538f4836-1Teo, Koon60475883-56ab-4acc-833d-b027ad828534-1Temizhan, Ahmet626c731f-6484-4126-b211-2d9f81423b38-1Wittlinger, Thomas68f3af13-e7ce-4705-820d-5a45b49f840f-1Maggioni, Aldo P.cffeb2b7-a22b-437a-9feb-8971ddf92836-1Lanas, Fernandod22b7fe4-9f1f-4028-a22b-be782ef03d3c-1Lopez-Jaramillo, Patricio9a71267b-dcb0-4d31-b37d-2d30be58d4d2-1Silva-Cardoso, José3076f9fa-3b99-4b47-bd29-1bf616f16363-1Sliwa, Karen7ff2b80f-9412-4d65-99cd-7d01d5578687-1Dokainish, Hisham18ada750-a3b5-424f-a7c2-ec2ddfcbdcbe-1Grinvalds, Alex38100a2b-7f5f-45a0-a613-3482e10ab354-1McCready, Tara2e01aadd-bde9-4281-96ec-00e0c64a8a5d-1Yusuf, Salim06a836b5-f5e3-41d9-a516-9cc46e5d7948-1G-CHF Investigatorsc346abf5-f3b6-4f6e-a3a8-cb17d64adc64-1Masira2022-02-18T14:34:04Z2022-02-18T14:34:04Z2021-04-28DigitalBackground: Poor health-related quality of life (HRQL) is common in heart failure (HF), but there are few data on HRQL in HF and the association between HRQL and mortality outside Western countries. Methods: We used the Kansas City Cardiomyopathy Questionnaire–12 (KCCQ-12) to record HRQL in 23 291 patients with HF from 40 countries in 8 different world regions in the G-CHF study (Global Congestive Heart Failure). We compared standardized KCCQ-12 summary scores (adjusted for age, sex, and markers of HF severity) among regions (scores range from 0 to 100, with higher score indicating better HRQL). We used multivariable Cox regression with adjustment for 15 variables to assess the association between KCCQ-12 summary scores and the composite of all-cause death, HF hospitalization, and each component over a median follow-up of 1.6 years. Results: The mean age of participants was 65 years; 61% were men; 40% had New York Heart Association class III or IV symptoms; and 46% had left ventricular ejection fraction ≥40%. Average HRQL differed between regions (lowest in Africa [mean± SE, 39.5±0.3], highest in Western Europe [62.5±0.4]). There were 4460 (19%) deaths, 3885 (17%) HF hospitalizations, and 6949 (30%) instances of either event. Lower KCCQ-12 summary score was associated with higher risk of all outcomes; the adjusted hazard ratio (HR) for each 10-unit KCCQ-12 summary score decrement was 1.18 (95% CI, 1.17–1.20) for death. Although this association was observed in all regions, it was less marked in South Asia, South America, and Africa (weakest association in South Asia: HR, 1.08 [95% CI, 1.03–1.14]; strongest association in Eastern Europe: HR, 1.31 [95% CI, 1.21–1.42]; interaction P<0.0001). Lower HRQL predicted death in patients with New York Heart Association class I or II and III or IV symptoms (HR, 1.17 [95% CI, 1.14–1.19] and HR, 1.14 [95% CI, 1.12–1.17]; interaction P=0.13) and was a stronger predictor for the composite outcome in New York Heart Association class I or II versus class III or IV (HR 1.15 [95% CI, 1.13–1.17] versus 1.09 [95% CI, [1.07–1.11]; interaction P<0.0001). HR for death was greater in ejection fraction ≥40 versus <40% (HR, 1.23 [95% CI, 1.20–1.26] and HR, 1.15 [95% CI, 1.13–1.17]; interaction P<0.0001). Conclusion: HRQL is a strong and independent predictor of all-cause death and HF hospitalization across all geographic regions, in mildly and severe symptomatic HF, and among patients with preserved and reduced ejection fraction.Ciencias Medicas y de la Salud14 papplication/pdfhttps://doi.org/10.1161/CIRCULATIONAHA.120.050850https://repositorio.udes.edu.co/handle/001/6046engAmerican Heart Association, Inc.USA1242222129143ScopusCirculation© 2021 American Heart Association, Inc.info:eu-repo/semantics/openAccessAtribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)https://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.120.050850Health-related quality of life and mortality in heart failure. The global congestive heart failure study of 23000 patients from 40 countriesArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85Todas las AudienciasPublicationORIGINALHealth-related quality of life and mortality in heart failure. The global congestive heart failure study of 23000 patients from 40 countries.pdfHealth-related quality of life and mortality in heart failure. The global congestive heart failure study of 23000 patients from 40 countries.pdfapplication/pdf241617https://repositorio.udes.edu.co/bitstreams/a61ba420-a0e1-4438-a034-77ec80ea3237/downloadb9a8a08bd3b7f846c8cf4ecab569ab8aMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-859https://repositorio.udes.edu.co/bitstreams/34ee1432-e698-4e82-836d-4af2d062b779/download38d94cf55aa1bf2dac1a736ac45c881cMD52TEXTHealth-related quality of life and mortality in heart failure. The global congestive heart failure study of 23000 patients from 40 countries.pdf.txtHealth-related quality of life and mortality in heart failure. The global congestive heart failure study of 23000 patients from 40 countries.pdf.txtExtracted texttext/plain5https://repositorio.udes.edu.co/bitstreams/32968c3d-2cce-4057-a56a-c00293ce103e/download5dbe86c1111d64f45ba435df98fdc825MD53THUMBNAILHealth-related quality of life and mortality in heart failure. 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