Prognostic validation of a non-laboratory and a laboratory based cardiovascular disease risk score in multiple regions of the world

7 p.

Autores:
Joseph, Philip
Yusuf, Salim
Lee, Shun Fu
Ibrahim, Quazi
Teo, Koon
Rangarajan, Sumathy
Gupta, Rajeev
Rosengren, Annika
Lear, Scott A.
Avezum, Alvaro
Lopez-Jaramillo, Patricio
Gulec, Sadi
Yusufali, Afzalhussein
Chifamba, Jephat
Lanas, Fernando
Kumar, Rajesh
Mohammadifard, Noushin
Mohan, Viswanathan
Mony, Prem
Kruger, Annamarie
Liu, Xu
Guo, Baoxia
Zhao, Wenqi
Yang, Youzhu
Pillai, Rajamohanan
Diaz, Rafael
Krishnapillai, Ambigga
Iqbal, Romaina
Yusuf, Rita
Szuba, Andrzej
Anand, Sonia S.
Tipo de recurso:
Article of journal
Fecha de publicación:
2018
Institución:
Universidad de Santander
Repositorio:
Repositorio Universidad de Santander
Idioma:
eng
OAI Identifier:
oai:repositorio.udes.edu.co:001/3315
Acceso en línea:
https://repositorio.udes.edu.co/handle/001/3315
Palabra clave:
cardiovascular disease
Risk Score
Rights
openAccess
License
Derechos Reservados - Heart, 2018
id RUDES2_b5782bcc3ce8443a8ddfc9c80974f837
oai_identifier_str oai:repositorio.udes.edu.co:001/3315
network_acronym_str RUDES2
network_name_str Repositorio Universidad de Santander
repository_id_str
dc.title.eng.fl_str_mv Prognostic validation of a non-laboratory and a laboratory based cardiovascular disease risk score in multiple regions of the world
title Prognostic validation of a non-laboratory and a laboratory based cardiovascular disease risk score in multiple regions of the world
spellingShingle Prognostic validation of a non-laboratory and a laboratory based cardiovascular disease risk score in multiple regions of the world
cardiovascular disease
Risk Score
title_short Prognostic validation of a non-laboratory and a laboratory based cardiovascular disease risk score in multiple regions of the world
title_full Prognostic validation of a non-laboratory and a laboratory based cardiovascular disease risk score in multiple regions of the world
title_fullStr Prognostic validation of a non-laboratory and a laboratory based cardiovascular disease risk score in multiple regions of the world
title_full_unstemmed Prognostic validation of a non-laboratory and a laboratory based cardiovascular disease risk score in multiple regions of the world
title_sort Prognostic validation of a non-laboratory and a laboratory based cardiovascular disease risk score in multiple regions of the world
dc.creator.fl_str_mv Joseph, Philip
Yusuf, Salim
Lee, Shun Fu
Ibrahim, Quazi
Teo, Koon
Rangarajan, Sumathy
Gupta, Rajeev
Rosengren, Annika
Lear, Scott A.
Avezum, Alvaro
Lopez-Jaramillo, Patricio
Gulec, Sadi
Yusufali, Afzalhussein
Chifamba, Jephat
Lanas, Fernando
Kumar, Rajesh
Mohammadifard, Noushin
Mohan, Viswanathan
Mony, Prem
Kruger, Annamarie
Liu, Xu
Guo, Baoxia
Zhao, Wenqi
Yang, Youzhu
Pillai, Rajamohanan
Diaz, Rafael
Krishnapillai, Ambigga
Iqbal, Romaina
Yusuf, Rita
Szuba, Andrzej
Anand, Sonia S.
dc.contributor.author.spa.fl_str_mv Joseph, Philip
Yusuf, Salim
Lee, Shun Fu
Ibrahim, Quazi
Teo, Koon
Rangarajan, Sumathy
Gupta, Rajeev
Rosengren, Annika
Lear, Scott A.
Avezum, Alvaro
Lopez-Jaramillo, Patricio
Gulec, Sadi
Yusufali, Afzalhussein
Chifamba, Jephat
Lanas, Fernando
Kumar, Rajesh
Mohammadifard, Noushin
Mohan, Viswanathan
Mony, Prem
Kruger, Annamarie
Liu, Xu
Guo, Baoxia
Zhao, Wenqi
Yang, Youzhu
Pillai, Rajamohanan
Diaz, Rafael
Krishnapillai, Ambigga
Iqbal, Romaina
Yusuf, Rita
Szuba, Andrzej
Anand, Sonia S.
dc.subject.proposal.eng.fl_str_mv cardiovascular disease
Risk Score
topic cardiovascular disease
Risk Score
description 7 p.
publishDate 2018
dc.date.issued.spa.fl_str_mv 2018
dc.date.accessioned.spa.fl_str_mv 2019-07-09T16:40:35Z
dc.date.available.spa.fl_str_mv 2019-07-09T16:40:35Z
dc.type.spa.fl_str_mv Artículo de revista
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.spa.fl_str_mv http://purl.org/coar/resource_type/c_6501
dc.type.content.spa.fl_str_mv Text
dc.type.driver.spa.fl_str_mv info:eu-repo/semantics/article
dc.type.redcol.spa.fl_str_mv http://purl.org/redcol/resource_type/ART
dc.type.version.spa.fl_str_mv info:eu-repo/semantics/publishedVersion
format http://purl.org/coar/resource_type/c_6501
status_str publishedVersion
dc.identifier.doi.eng.fl_str_mv 10.1136/heartjnl-2017-311609
dc.identifier.issn.spa.fl_str_mv 1355-6037
1468-201X
dc.identifier.uri.spa.fl_str_mv https://repositorio.udes.edu.co/handle/001/3315
identifier_str_mv 10.1136/heartjnl-2017-311609
1355-6037
1468-201X
url https://repositorio.udes.edu.co/handle/001/3315
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.ispartof.eng.fl_str_mv Heart
dc.rights.spa.fl_str_mv Derechos Reservados - Heart, 2018
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.accessrights.spa.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.creativecommons.spa.fl_str_mv Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)
dc.rights.uri.spa.fl_str_mv https://creativecommons.org/licenses/by-nc/4.0/
rights_invalid_str_mv Derechos Reservados - Heart, 2018
Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)
https://creativecommons.org/licenses/by-nc/4.0/
http://purl.org/coar/access_right/c_abf2
eu_rights_str_mv openAccess
dc.format.mimetype.spa.fl_str_mv application/pdf
dc.source.eng.fl_str_mv https://heart.bmj.com/content/heartjnl/104/7/581.full.pdf
institution Universidad de Santander
bitstream.url.fl_str_mv https://repositorio.udes.edu.co/bitstreams/84374319-7141-4505-b48b-bde414b029b1/download
https://repositorio.udes.edu.co/bitstreams/1a91b400-cae2-47e4-a20c-09effc544771/download
https://repositorio.udes.edu.co/bitstreams/fdf0df94-9dbd-41ac-a5c4-a6dca02c0193/download
https://repositorio.udes.edu.co/bitstreams/e905a122-f652-4781-af1a-43993e3e0732/download
https://repositorio.udes.edu.co/bitstreams/9675ec56-c0e8-4362-90ec-e6cad6bade3a/download
bitstream.checksum.fl_str_mv 237ab7d4c050d014bccf98e8cd71693d
61d09dc4ebe43ed07b932818a0a4588f
a461382bc685ac3a60b140966d4df4b6
38d94cf55aa1bf2dac1a736ac45c881c
5154fc3bbc6893803729974058ed0d68
bitstream.checksumAlgorithm.fl_str_mv MD5
MD5
MD5
MD5
MD5
repository.name.fl_str_mv Repositorio Universidad de Santander
repository.mail.fl_str_mv soporte@metabiblioteca.com
_version_ 1808490847130353664
spelling Joseph, Philip35ddb523-bb0e-4c55-9a59-b24968824fbf-1Yusuf, Salim06a836b5-f5e3-41d9-a516-9cc46e5d7948-1Lee, Shun Fu4581e29f-0fc3-4c3c-a05a-0d0c2133eb61-1Ibrahim, Quazif9560a36-d6c6-4042-bf0e-ac209d1e1024-1Teo, Koon60475883-56ab-4acc-833d-b027ad828534-1Rangarajan, Sumathy5466c363-e515-4bd2-8537-eb839320f385-1Gupta, Rajeevde1826df-aac8-4d9f-9b84-f21ba704686c-1Rosengren, Annika923779f9-3a92-4086-b3d9-9d78974926d9-1Lear, Scott A.dc924e5a-246b-40a8-b08f-59610fa89be1-1Avezum, Alvaro8b920360-abb2-4ec8-b5ee-4e3f4e0b11eb-1Lopez-Jaramillo, Patricio9a71267b-dcb0-4d31-b37d-2d30be58d4d2-1Gulec, Sadi877f5289-b16d-4a48-bd64-a1886f2c2a73-1Yusufali, Afzalhussein2c177fd9-b761-4f07-b754-1e05fe659a48-1Chifamba, Jephatf2496279-e934-40b8-8f61-0039a09f03f8-1Lanas, Fernandod22b7fe4-9f1f-4028-a22b-be782ef03d3c-1Kumar, Rajesh649d5d1b-c303-4964-9ed4-657eb4a715df-1Mohammadifard, Noushin24262688-da4b-4bdf-9ced-4eb264282354-1Mohan, Viswanathane7246d73-7de3-4d86-9c7b-b9ca011e618b-1Mony, Premab6dbf82-20a0-4744-abfd-8a723db46c4d-1Kruger, Annamarie1253e46a-fa0d-4d1e-9ef7-0e9daf520039-1Liu, Xuab6021e3-4c59-4776-b89a-1df2b0be3231-1Guo, Baoxiaa4e6de71-e187-45b4-9408-e13ad3d21b16-1Zhao, Wenqi4f87e5ba-c6cb-43ca-8b7d-63c54e85c461-1Yang, Youzhuee2a589c-f68a-4f4f-910d-d1c8c3fee46a-1Pillai, Rajamohananbd9f59a8-fbef-451a-94fe-a18ea74d1d49-1Diaz, Rafaelf2be4a74-501a-4e63-8bbd-965cbcf8c57b-1Krishnapillai, Ambigga20fca8c5-887f-425a-9642-e74c88e138f2-1Iqbal, Romaina015cbc16-dd01-4e26-adff-257bb8827f50-1Yusuf, Rita73629390-dae0-4d21-aca0-90da88bd2808-1Szuba, Andrzej66d9d177-80f1-4191-9e5f-ef493dc7c253-1Anand, Sonia S.76cdf575-775c-4053-960b-9820a2f9db2d-12019-07-09T16:40:35Z2019-07-09T16:40:35Z20187 p.Objective To evaluate the performance of the non-laboratory INTERHEART risk score (NL-IHRS) to predict incident cardiovascular disease (CVD) across seven major geographic regions of the world. The secondary objective was to evaluate the performance of the fasting cholesterol-based IHRS (FC-IHRS). Methods Using measures of discrimination and calibration, we tested the performance of the NL-IHRS (n=100 475) and FC-IHRS (n=107 863) for predicting incident CVD in a community-based, prospective study across seven geographic regions: South Asia, China, Southeast Asia, Middle East, Europe/North America, South America and Africa. CVD was defined as the composite of cardiovascular death, myocardial infarction, stroke, heart failure or coronary revascularisation. Results Mean age of the study population was 50.53 (SD 9.79) years and mean follow-up was 4.89 (SD 2.24) years. The NL-IHRS had moderate to good discrimination for incident CVD across geographic regions (concordance statistic (C-statistic) ranging from 0.64 to 0.74), although recalibration was necessary in all regions, which improved its performance in the overall cohort (increase in C-statistic from 0.69 to 0.72, p<0.001). Regional recalibration was also necessary for the FC-IHRS, which also improved its overall discrimination (increase in C-statistic from 0.71 to 0.74, p<0.001). In 85 078 participants with complete data for both scores, discrimination was only modestly better with the FC-IHRS compared with the NL-IHRS (0.74 vs 0.73, p<0.001). Conclusions External validations of the NL-IHRS and FC-IHRS suggest that regionally recalibrated versions of both can be useful for estimating CVD risk across a diverse range of community-based populations. CVD prediction using a non-laboratory score can provide similar accuracy to laboratory-based methods.application/pdf10.1136/heartjnl-2017-3116091355-60371468-201Xhttps://repositorio.udes.edu.co/handle/001/3315engHeartDerechos Reservados - Heart, 2018info:eu-repo/semantics/openAccessAtribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)https://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2https://heart.bmj.com/content/heartjnl/104/7/581.full.pdfcardiovascular diseaseRisk ScorePrognostic validation of a non-laboratory and a laboratory based cardiovascular disease risk score in multiple regions of the worldArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85PublicationTHUMBNAILPrognostic validation of a non-laboratory and a laboratory based cardiovascular disease risk score in multiple regions of the world.pdf.jpgPrognostic validation of a non-laboratory and a laboratory based cardiovascular disease risk score in multiple regions of the world.pdf.jpgGenerated Thumbnailimage/jpeg1566https://repositorio.udes.edu.co/bitstreams/84374319-7141-4505-b48b-bde414b029b1/download237ab7d4c050d014bccf98e8cd71693dMD57TEXTPrognostic validation of a non-laboratory and a laboratory based cardiovascular disease risk score....pdf.txtPrognostic validation of a non-laboratory and a laboratory based cardiovascular disease risk score....pdf.txtExtracted texttext/plain45012https://repositorio.udes.edu.co/bitstreams/1a91b400-cae2-47e4-a20c-09effc544771/download61d09dc4ebe43ed07b932818a0a4588fMD53Prognostic validation of a non-laboratory and a laboratory based cardiovascular disease risk score in multiple regions of the world.pdf.txtPrognostic validation of a non-laboratory and a laboratory based cardiovascular disease risk score in multiple regions of the world.pdf.txtExtracted texttext/plain48191https://repositorio.udes.edu.co/bitstreams/fdf0df94-9dbd-41ac-a5c4-a6dca02c0193/downloada461382bc685ac3a60b140966d4df4b6MD59LICENSElicense.txtlicense.txttext/plain; charset=utf-859https://repositorio.udes.edu.co/bitstreams/e905a122-f652-4781-af1a-43993e3e0732/download38d94cf55aa1bf2dac1a736ac45c881cMD52ORIGINALPrognostic validation of a non-laboratory and a laboratory based cardiovascular disease risk score in multiple regions of the world.pdfArtículo Principalapplication/pdf318852https://repositorio.udes.edu.co/bitstreams/9675ec56-c0e8-4362-90ec-e6cad6bade3a/download5154fc3bbc6893803729974058ed0d68MD58001/3315oai:repositorio.udes.edu.co:001/33152023-10-10 08:52:51.868https://creativecommons.org/licenses/by-nc/4.0/Derechos Reservados - Heart, 2018https://repositorio.udes.edu.coRepositorio Universidad de Santandersoporte@metabiblioteca.comTGljZW5jaWEgZGUgUHVibGljYWNpw7NuIFVERVMKRGlyZWN0cmljZXMgZGUgVVNPIHkgQUNDRVNPCgo=