Prevalence and molecular typing of rotavirus in children with acute diarrhoea in Northeastern Colombia

Digital

Autores:
Martínez Gutiérrez, Marlen
Arcila Quiceno, Victor
Trejos Suárez, Juanita
Ruiz Saenz, Julian
Tipo de recurso:
Article of journal
Fecha de publicación:
2019
Institución:
Universidad de Santander
Repositorio:
Repositorio Universidad de Santander
Idioma:
eng
OAI Identifier:
oai:repositorio.udes.edu.co:001/5659
Acceso en línea:
https://repositorio.udes.edu.co/handle/001/5659
Palabra clave:
Acute diarrhoea
Colombia
Molecular characterization
Post-vaccination
Rotavirus
Rights
openAccess
License
The Editor(s) and the Author(s), 2019
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oai_identifier_str oai:repositorio.udes.edu.co:001/5659
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network_name_str Repositorio Universidad de Santander
repository_id_str
dc.title.spa.fl_str_mv Prevalence and molecular typing of rotavirus in children with acute diarrhoea in Northeastern Colombia
title Prevalence and molecular typing of rotavirus in children with acute diarrhoea in Northeastern Colombia
spellingShingle Prevalence and molecular typing of rotavirus in children with acute diarrhoea in Northeastern Colombia
Acute diarrhoea
Colombia
Molecular characterization
Post-vaccination
Rotavirus
title_short Prevalence and molecular typing of rotavirus in children with acute diarrhoea in Northeastern Colombia
title_full Prevalence and molecular typing of rotavirus in children with acute diarrhoea in Northeastern Colombia
title_fullStr Prevalence and molecular typing of rotavirus in children with acute diarrhoea in Northeastern Colombia
title_full_unstemmed Prevalence and molecular typing of rotavirus in children with acute diarrhoea in Northeastern Colombia
title_sort Prevalence and molecular typing of rotavirus in children with acute diarrhoea in Northeastern Colombia
dc.creator.fl_str_mv Martínez Gutiérrez, Marlen
Arcila Quiceno, Victor
Trejos Suárez, Juanita
Ruiz Saenz, Julian
dc.contributor.author.none.fl_str_mv Martínez Gutiérrez, Marlen
Arcila Quiceno, Victor
Trejos Suárez, Juanita
Ruiz Saenz, Julian
dc.contributor.researchgroup.spa.fl_str_mv CLINIUDES
dc.subject.proposal.eng.fl_str_mv Acute diarrhoea
Colombia
Molecular characterization
Post-vaccination
Rotavirus
topic Acute diarrhoea
Colombia
Molecular characterization
Post-vaccination
Rotavirus
description Digital
publishDate 2019
dc.date.issued.none.fl_str_mv 2019-06-01
dc.date.accessioned.none.fl_str_mv 2021-10-05T21:21:20Z
dc.date.available.none.fl_str_mv 2021-10-05T21:21:20Z
dc.type.spa.fl_str_mv Artículo de revista
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dc.identifier.doi.none.fl_str_mv 10.1590/S1678-9946201961034.
dc.identifier.uri.none.fl_str_mv https://repositorio.udes.edu.co/handle/001/5659
identifier_str_mv 10.1590/S1678-9946201961034.
url https://repositorio.udes.edu.co/handle/001/5659
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.citationendpage.spa.fl_str_mv 10
dc.relation.citationissue.spa.fl_str_mv 34, julio 2019.
dc.relation.citationstartpage.spa.fl_str_mv 1
dc.relation.citationvolume.spa.fl_str_mv 61
dc.relation.cites.none.fl_str_mv Martinez-Gutierrez M, Arcila-Quiceno V, Trejos-Suarez J, Ruiz-Saenz J. Prevalence and molecular typing of rotavirus in children with acute diarrhoea in Northeastern Colombia. Rev Inst Med Trop Sao Paulo. 2019 Jul 1;61:e34. doi: 10.1590/S1678-9946201961034. PMID: 31269110; PMCID: PMC6609135.
dc.relation.indexed.spa.fl_str_mv Rev Inst Med Trop Sao Paulo . 2019 Jul 1;61:e34. doi: 10.1590/S1678-9946201961034.
dc.relation.ispartofjournal.spa.fl_str_mv Revista do Instituto de Medicina Tropical de Sao Paulo
dc.rights.spa.fl_str_mv The Editor(s) and the Author(s), 2019
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
dc.rights.accessrights.spa.fl_str_mv info:eu-repo/semantics/openAccess
dc.rights.creativecommons.spa.fl_str_mv Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)
dc.rights.uri.spa.fl_str_mv https://creativecommons.org/licenses/by-nc/4.0/
rights_invalid_str_mv The Editor(s) and the Author(s), 2019
Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)
https://creativecommons.org/licenses/by-nc/4.0/
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eu_rights_str_mv openAccess
dc.format.extent.spa.fl_str_mv 1 p
dc.format.mimetype.spa.fl_str_mv application/pdf
dc.publisher.spa.fl_str_mv Revista do Instituto de Medicina Tropical de Sao Paulo
dc.publisher.place.spa.fl_str_mv Sao Paulo, Brasil
dc.source.spa.fl_str_mv https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609135/pdf/1678-9946-rimtsp-61-S1678-9946201961034.pdf
institution Universidad de Santander
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spelling Martínez Gutiérrez, Marlen92bafe7d-5768-4f16-a861-1d5a7486c5bc-1Arcila Quiceno, Victor3515643b-bc36-4b76-bec8-7439dd2d4b77-1Trejos Suárez, Juanitad1ff80c8-4661-4ad3-8cc1-ac4b0fe1abe3-1Ruiz Saenz, Julian827f4fa2-52e4-40a5-b081-9e1d95950338-1CLINIUDES2021-10-05T21:21:20Z2021-10-05T21:21:20Z2019-06-01DigitalAfter the introduction of the rotavirus vaccine, the number of rotavirus-associated deaths and the predicted annual rotavirus detection rate had slightly declined worldwide. Taking in account that in Colombia, Rotarix vaccine was introduced in 2009, the purpose of this study was to evaluate the presence of rotavirus A in children under five years who were treated for acute diarrhoea in Bucaramanga, Colombia and, moreover, to determine the genotypes of rotavirus present in those children. We performed an analytical cross-sectional study of rotavirus A in faecal samples from children up to five years of age. Stool samples were screened for rotavirus A using a lateral-flow immunochromatographic assay and confirmed using a VP6 sandwich ELISA. Genotyping of rotavirus A-positive samples was performed by PCR and sequencing of VP7 and VP4 genes. The overall prevalence of rotavirus was 30.53% (95% confidence interval [CI] 21.2 - 39.7). Most of the children with rotavirus (86.2%) had received two doses of the rotavirus vaccine. G3 strains accounted for the vast majority of cases (82.8%), followed by G12 strains (13.8%) and G3/G9 coinfections (3.4%). Among the P genotypes, P[8] was the most prevalent (69%), followed by P[9] (31%). The most common G[P] genotype combination was G3P[8], followed by G3P[9]. The main finding in this study was that rotavirus, in a Colombian region, is still an important pathogen in children under five years old, previously vaccinated. The results showed that different factors, such as kindergarten attendance, could explain the epidemiology and transmission of rotavirus in Bucaramanga.Ciencias básicas biomédicas, epidemiología, salud pública, enfermedades infecciosas, enfermedades no transmisibles epidemiología, salud y desarrollo, discapacidad1 papplication/pdf10.1590/S1678-9946201961034.https://repositorio.udes.edu.co/handle/001/5659engRevista do Instituto de Medicina Tropical de Sao PauloSao Paulo, Brasil1034, julio 2019.161Martinez-Gutierrez M, Arcila-Quiceno V, Trejos-Suarez J, Ruiz-Saenz J. Prevalence and molecular typing of rotavirus in children with acute diarrhoea in Northeastern Colombia. Rev Inst Med Trop Sao Paulo. 2019 Jul 1;61:e34. doi: 10.1590/S1678-9946201961034. PMID: 31269110; PMCID: PMC6609135.Rev Inst Med Trop Sao Paulo . 2019 Jul 1;61:e34. doi: 10.1590/S1678-9946201961034.Revista do Instituto de Medicina Tropical de Sao PauloThe Editor(s) and the Author(s), 2019info:eu-repo/semantics/openAccessAtribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)https://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6609135/pdf/1678-9946-rimtsp-61-S1678-9946201961034.pdfAcute diarrhoeaColombiaMolecular characterizationPost-vaccinationRotavirusPrevalence and molecular typing of rotavirus in children with acute diarrhoea in Northeastern ColombiaArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85Todas las AudienciasPublicationORIGINALPrevalence and molecular typing of rotavirus in children with acute diarrhoea in Northeastern Colombia.pdfPrevalence and molecular typing of rotavirus in children with acute diarrhoea in Northeastern Colombia.pdfapplication/pdf179954https://repositorio.udes.edu.co/bitstreams/aac30516-840c-44bd-b381-18033ee1a832/downloadaa23235679295ddc73a2306087669cc9MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-859https://repositorio.udes.edu.co/bitstreams/f1ca88cd-e111-4e84-b219-9c4d2acf54a3/download38d94cf55aa1bf2dac1a736ac45c881cMD52TEXTPrevalence and molecular typing of rotavirus in children with acute diarrhoea in Northeastern Colombia.pdf.txtPrevalence and molecular typing of rotavirus in children with acute diarrhoea in Northeastern Colombia.pdf.txtExtracted texttext/plain5https://repositorio.udes.edu.co/bitstreams/5bac231c-6803-4123-af04-8414f8915e0e/download5dbe86c1111d64f45ba435df98fdc825MD53THUMBNAILPrevalence and molecular typing of rotavirus in children with acute diarrhoea in Northeastern Colombia.pdf.jpgPrevalence and molecular typing of rotavirus in children with acute diarrhoea in Northeastern Colombia.pdf.jpgGenerated Thumbnailimage/jpeg12277https://repositorio.udes.edu.co/bitstreams/8d9983dd-b7a2-4705-ac8b-be317aee0bbc/downloadf15625492262fd7be7c13824fa8c3ae4MD54001/5659oai:repositorio.udes.edu.co:001/56592023-10-10 09:42:34.702https://creativecommons.org/licenses/by-nc/4.0/The Editor(s) and the Author(s), 2019https://repositorio.udes.edu.coRepositorio Universidad de Santandersoporte@metabiblioteca.comTGljZW5jaWEgZGUgUHVibGljYWNpw7NuIFVERVMKRGlyZWN0cmljZXMgZGUgVVNPIHkgQUNDRVNPCgo=