Association of urinary sodium excretion with blood pressure and cardiovascular clinical events in 17,033 Latin americans
10 p.
- Autores:
-
Lamelas, Pablo M.
Mente, Andrew
Diaz, Rafael
Orlandini, Andres
Avezum, Alvaro
Oliveira, Gustavo
Lanas, Fernando
Seron, Pamela
Lopez-Jaramillo, Patricio
Camacho López, Paul Anthony
O’Donnell, Martin J.
Rangarajan, Sumathy
Teo, Koon
Yusuf, Salim
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2016
- Institución:
- Universidad de Santander
- Repositorio:
- Repositorio Universidad de Santander
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.udes.edu.co:001/3244
- Acceso en línea:
- https://repositorio.udes.edu.co/handle/001/3244
- Palabra clave:
- Sodium intake
Blood pressure
Cardiovascular disease
Hypertension
Mortality
- Rights
- openAccess
- License
- Derechos Reservados - American Journal of Hypertension, Ltd, 2016
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Association of urinary sodium excretion with blood pressure and cardiovascular clinical events in 17,033 Latin americans |
| title |
Association of urinary sodium excretion with blood pressure and cardiovascular clinical events in 17,033 Latin americans |
| spellingShingle |
Association of urinary sodium excretion with blood pressure and cardiovascular clinical events in 17,033 Latin americans Sodium intake Blood pressure Cardiovascular disease Hypertension Mortality |
| title_short |
Association of urinary sodium excretion with blood pressure and cardiovascular clinical events in 17,033 Latin americans |
| title_full |
Association of urinary sodium excretion with blood pressure and cardiovascular clinical events in 17,033 Latin americans |
| title_fullStr |
Association of urinary sodium excretion with blood pressure and cardiovascular clinical events in 17,033 Latin americans |
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Association of urinary sodium excretion with blood pressure and cardiovascular clinical events in 17,033 Latin americans |
| title_sort |
Association of urinary sodium excretion with blood pressure and cardiovascular clinical events in 17,033 Latin americans |
| dc.creator.fl_str_mv |
Lamelas, Pablo M. Mente, Andrew Diaz, Rafael Orlandini, Andres Avezum, Alvaro Oliveira, Gustavo Lanas, Fernando Seron, Pamela Lopez-Jaramillo, Patricio Camacho López, Paul Anthony O’Donnell, Martin J. Rangarajan, Sumathy Teo, Koon Yusuf, Salim |
| dc.contributor.author.spa.fl_str_mv |
Lamelas, Pablo M. Mente, Andrew Diaz, Rafael Orlandini, Andres Avezum, Alvaro Oliveira, Gustavo Lanas, Fernando Seron, Pamela Lopez-Jaramillo, Patricio Camacho López, Paul Anthony O’Donnell, Martin J. Rangarajan, Sumathy Teo, Koon Yusuf, Salim |
| dc.subject.proposal.eng.fl_str_mv |
Sodium intake Blood pressure Cardiovascular disease Hypertension Mortality |
| topic |
Sodium intake Blood pressure Cardiovascular disease Hypertension Mortality |
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10 p. |
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2016 |
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2016-07 |
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2019-07-02T14:10:11Z |
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2019-07-02T14:10:11Z |
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10.1093/ajh/hpv195 1941-7225 0895-7061 |
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https://repositorio.udes.edu.co/handle/001/3244 |
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10.1093/ajh/hpv195 1941-7225 0895-7061 |
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eng |
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eng |
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American Journal of Hypertension |
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Derechos Reservados - American Journal of Hypertension, Ltd, 2016 |
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Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0) |
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Derechos Reservados - American Journal of Hypertension, Ltd, 2016 Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0) https://creativecommons.org/licenses/by-nc/4.0/ http://purl.org/coar/access_right/c_abf2 |
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Lamelas, Pablo M.1225bf77-98c8-4037-8320-6df2320ce51f-1Mente, Andrew9a80b664-b49e-4fce-961e-b7dd6e07a3ab-1Diaz, Rafaelf2be4a74-501a-4e63-8bbd-965cbcf8c57b-1Orlandini, Andrescbafea09-3a82-4064-a22f-d34a0e7583d4-1Avezum, Alvaro8b920360-abb2-4ec8-b5ee-4e3f4e0b11eb-1Oliveira, Gustavoa15f3ebc-753b-4b0a-9923-997eeb9ad7ba-1Lanas, Fernandod22b7fe4-9f1f-4028-a22b-be782ef03d3c-1Seron, Pamela95c6e76c-9891-4782-a399-b592acec2294-1Lopez-Jaramillo, Patricio9a71267b-dcb0-4d31-b37d-2d30be58d4d2-1Camacho López, Paul Anthony594e3832-d941-4df3-b3cc-a2c088dca74c-1O’Donnell, Martin J.87baff49-ae1d-46bd-ad8a-0cbd6aecbacd-1Rangarajan, Sumathy5466c363-e515-4bd2-8537-eb839320f385-1Teo, Koon60475883-56ab-4acc-833d-b027ad828534-1Yusuf, Salim06a836b5-f5e3-41d9-a516-9cc46e5d7948-12019-07-02T14:10:11Z2019-07-02T14:10:11Z2016-0710 p.BACKGROUND: Information on actual sodium intake and its relationships with blood pressure (BP) and clinical events in South America is limited. The aim of this cohort study was to assess the relationship of sodium intake with BP, cardiovascular (CV) events, and mortality in South America. METHODS: We studied 17,033 individuals, aged 35–70 years, from 4 South American countries (Argentina, Brazil, Chile, and Colombia). Measures of sodium excretion, estimated from morning fasting urine, were used as a surrogate for daily sodium intake. We measured BP and monitored the composite outcome of death and major CV events. RESULTS: Overall mean sodium excretion was 4.70±1.43g/day. A positive, nonuniform association between sodium and BP was detected, with a significant steeper slope for the relationship at higher sodium excretion levels ( P < 0.001 for interaction). With a median follow-up of 4.7 years, the primary composite outcome (all-cause death, myocardial infarction, stroke, or heart failure) occurred in 568 participants (3.4%). Compared with sodium excretion of 5–6g/day (reference group), participants who excreted >7g/day had increased risks of the primary outcome (odds ratio (OR) 1.73; 95% confidence interval (CI) 1.24 to 2.40; P < 0.001), as well as death from any cause (OR 1.87; 95% CI 1.23 to 2.83; P = 0.003) and major CV disease (OR 1.77; 95% CI 1.12 to 2.81; P = 0.014). Sodium excretion of <3g/day was associated with a statistically nonsignificant increased risk of the primary outcome (OR 1.20; 95% CI 0.86 to 1.65; P = 0.26) and death from any cause (OR 1.25; 95% CI 0.81 to 1.93; P = 0.29), and a significant increased risk of major CV disease (OR 1.50; 95% CI 1.01 to 2.24; P = 0.048), as compared to the reference group. CONCLUSIONS: Our results support a positive, nonuniform association between estimated urinary sodium excretion and BP, and a possible J-shaped pattern of association between sodium excretion over the entire range and clinical outcomes.application/pdf10.1093/ajh/hpv1951941-72250895-7061https://repositorio.udes.edu.co/handle/001/3244engAmerican Journal of HypertensionDerechos Reservados - American Journal of Hypertension, Ltd, 2016info:eu-repo/semantics/openAccessAtribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)https://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2https://watermark.silverchair.com/hpv195.pdf?token=AQECAHi208BE49Ooan9kkhW_Ercy7Dm3ZL_9Cf3qfKAc485ysgAAAjcwggIzBgkqhkiG9w0BBwagggIkMIICIAIBADCCAhkGCSqGSIb3DQEHATAeBglghkgBZQMEAS4wEQQMapN2YPJ48mkzfgCJAgEQgIIB6jJzjkzriPNzKmnWWs41qg5WEVyGhNeaZyK-p_29najY8ezksKC4gEqfbQavJsb2AWpbC2m7VkpEyVB-_0hgz9U3ZfHfhkgEIicoEjxpCV4GEsONyJW1NxsCPEJjztBRWVIrQE_ZVdoW0LyPYhLfGJW5IMEHoIr03uhMj2jG2gWbWTiM_SMLAgVmW26Fffh15a7WU_-VMwTO6TXu5kCA1VkGVMZExrik2xx34RBIlcqf-PuWjuccLoppKNxvd1pl3OLf65XZvCPH0HThjEOtfGarcU5UCxnCyo_ptP5J6klDoj2aQNbPKIrJJX2uAafvmn6qUtaKSzo-HdQ4unr2DWoGtmLsXol2qn7sO_58Y-NfdsknP_toAcHHlPNG0iK-rBsAtwWx-d-iaA0ItGtFkfYWdw4s8xB_10eKq5Y-aJTWjIbPSehw24-Fw4sl37COJ_ihwEOuKKStrUZ0nam-3h2EEmnC19AlPg1herPUOEuufBvXafM6u8TwLh3enBFiCGAt8S6yYdJYgTiIDYJO09l-B_EVnJuWdmyGOwu68nNXWvhtF2omRwr8l73ZAUrwrClzcVqzIB8ez3wHdeSETMvZ-KUAKNAggRH-xK1jKJjKn4LzHJFRcP63UlXJEmdslWC7OR2jpMVtt9sSodium intakeBlood pressureCardiovascular diseaseHypertensionMortalityAssociation of urinary sodium excretion with blood pressure and cardiovascular clinical events in 17,033 Latin americansArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85PublicationTHUMBNAILAssociation of urinary sodium excretion with blood pressure and cardiovascular clinical events in 17,033 Latin americans.pdf.jpgAssociation of urinary sodium excretion with blood pressure and cardiovascular clinical events in 17,033 Latin americans.pdf.jpgGenerated Thumbnailimage/jpeg1857https://repositorio.udes.edu.co/bitstreams/e836ef56-9a2d-4ece-b897-71119faa4e3c/download7d74f27fd5dfa9bae929591fb7c27f86MD54LICENSElicense.txtlicense.txttext/plain; charset=utf-859https://repositorio.udes.edu.co/bitstreams/6e5ea97f-a551-4968-a1da-480a24f680e9/download38d94cf55aa1bf2dac1a736ac45c881cMD52ORIGINALAssociation of urinary sodium excretion with blood pressure and cardiovascular clinical events in 17,033 Latin americans.pdfArtículo Principalapplication/pdf1118729https://repositorio.udes.edu.co/bitstreams/1d422eef-a876-45a9-9208-8b407a5872cf/download083cc2499c83f162ea9013f09b8c51b4MD55TEXTAssociation of urinary sodium excretion with blood pressure and cardiovascular clinical events in 17,033 Latin americans.pdf.txtAssociation of urinary sodium excretion with blood pressure and cardiovascular clinical events in 17,033 Latin americans.pdf.txtExtracted texttext/plain46549https://repositorio.udes.edu.co/bitstreams/880d28b2-c7b6-484c-8b7f-d5596c8e51d1/download5651fef313ac5195f299a8b3e8cf86bbMD53001/3244oai:repositorio.udes.edu.co:001/32442023-10-10 08:56:11.512https://creativecommons.org/licenses/by-nc/4.0/Derechos Reservados - American Journal of Hypertension, Ltd, 2016https://repositorio.udes.edu.coRepositorio Universidad de Santandersoporte@metabiblioteca.comTGljZW5jaWEgZGUgUHVibGljYWNpw7NuIFVERVMKRGlyZWN0cmljZXMgZGUgVVNPIHkgQUNDRVNPCgo= |