Prognostic value of grip strength : Findings from the Prospective Urban Rural Epidemiology (PURE) study
8 p.
- Autores:
-
Leong, Darryl P.
Teo, Koon
Rangarajan, Sumathy
Lopez-Jaramillo, Patricio
Avezum, Alvaro
Orlandini, Andres
Seron, Pamela
Ahmed, Suad H.
Rosengren, Annika
Kelishadi, Roya
Rahman, Omar
Swaminathan, Sumathi
Iqbal, Romaina
Gupta, Rajeev
Lear, Scott A.
Oguz, Aytekin
Yusoff, Khalid
Zatonska, Katarzyna
Chifamba, Jephat
Igumbor, Ehimario
Mohan, Viswanathan
Anjana, Ranjit Mohan
Gu, Hongqiu
Li, Wei
Yusuf, Salim
The PURE (Prospective Urban Rural Epidemiology) Study investigators
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2015
- Institución:
- Universidad de Santander
- Repositorio:
- Repositorio Universidad de Santander
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.udes.edu.co:001/3538
- Acceso en línea:
- https://repositorio.udes.edu.co/handle/001/3538
- Palabra clave:
- Grip
Strength
- Rights
- openAccess
- License
- Derechos Reservados - The Lancet, 2015
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Prognostic value of grip strength : Findings from the Prospective Urban Rural Epidemiology (PURE) study |
| title |
Prognostic value of grip strength : Findings from the Prospective Urban Rural Epidemiology (PURE) study |
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Prognostic value of grip strength : Findings from the Prospective Urban Rural Epidemiology (PURE) study Grip Strength |
| title_short |
Prognostic value of grip strength : Findings from the Prospective Urban Rural Epidemiology (PURE) study |
| title_full |
Prognostic value of grip strength : Findings from the Prospective Urban Rural Epidemiology (PURE) study |
| title_fullStr |
Prognostic value of grip strength : Findings from the Prospective Urban Rural Epidemiology (PURE) study |
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Prognostic value of grip strength : Findings from the Prospective Urban Rural Epidemiology (PURE) study |
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Prognostic value of grip strength : Findings from the Prospective Urban Rural Epidemiology (PURE) study |
| dc.creator.fl_str_mv |
Leong, Darryl P. Teo, Koon Rangarajan, Sumathy Lopez-Jaramillo, Patricio Avezum, Alvaro Orlandini, Andres Seron, Pamela Ahmed, Suad H. Rosengren, Annika Kelishadi, Roya Rahman, Omar Swaminathan, Sumathi Iqbal, Romaina Gupta, Rajeev Lear, Scott A. Oguz, Aytekin Yusoff, Khalid Zatonska, Katarzyna Chifamba, Jephat Igumbor, Ehimario Mohan, Viswanathan Anjana, Ranjit Mohan Gu, Hongqiu Li, Wei Yusuf, Salim The PURE (Prospective Urban Rural Epidemiology) Study investigators |
| dc.contributor.author.spa.fl_str_mv |
Leong, Darryl P. Teo, Koon Rangarajan, Sumathy Lopez-Jaramillo, Patricio Avezum, Alvaro Orlandini, Andres Seron, Pamela Ahmed, Suad H. Rosengren, Annika Kelishadi, Roya Rahman, Omar Swaminathan, Sumathi Iqbal, Romaina Gupta, Rajeev Lear, Scott A. Oguz, Aytekin Yusoff, Khalid Zatonska, Katarzyna Chifamba, Jephat Igumbor, Ehimario Mohan, Viswanathan Anjana, Ranjit Mohan Gu, Hongqiu Li, Wei Yusuf, Salim |
| dc.contributor.author.eng.fl_str_mv |
The PURE (Prospective Urban Rural Epidemiology) Study investigators |
| dc.subject.proposal.eng.fl_str_mv |
Grip Strength |
| topic |
Grip Strength |
| description |
8 p. |
| publishDate |
2015 |
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2015-07 |
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2019-08-06T16:28:00Z |
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2019-08-06T16:28:00Z |
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Artículo de revista |
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10.1016/S0140-6736(14)62000-6 |
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0140-6736 |
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eng |
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eng |
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The Lancet |
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Derechos Reservados - The Lancet, 2015 |
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http://purl.org/coar/access_right/c_abf2 |
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info:eu-repo/semantics/openAccess |
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Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0) |
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https://creativecommons.org/licenses/by-nc/4.0/ |
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Leong, Darryl P.707b53c2-976c-44c2-a420-3de6a35f35e8-1Teo, Koon60475883-56ab-4acc-833d-b027ad828534-1Rangarajan, Sumathy5466c363-e515-4bd2-8537-eb839320f385-1Lopez-Jaramillo, Patricio9a71267b-dcb0-4d31-b37d-2d30be58d4d2-1Avezum, Alvaro8b920360-abb2-4ec8-b5ee-4e3f4e0b11eb-1Orlandini, Andrescbafea09-3a82-4064-a22f-d34a0e7583d4-1Seron, Pamela95c6e76c-9891-4782-a399-b592acec2294-1Ahmed, Suad H.cd246be8-16b1-4fb1-8fcb-5bca3bac401c-1Rosengren, Annika923779f9-3a92-4086-b3d9-9d78974926d9-1Kelishadi, Roya4cdb25d6-6e41-4905-a399-c9d53f250b42-1Rahman, Omar2fdf224c-97c9-4fb0-b7a9-ea79427bc631-1Swaminathan, Sumathi2df52946-d5e9-441c-b38e-cd33e6fc3722-1Iqbal, Romaina015cbc16-dd01-4e26-adff-257bb8827f50-1Gupta, Rajeevde1826df-aac8-4d9f-9b84-f21ba704686c-1Lear, Scott A.19eb29a4-5987-41b9-a400-130692ec0232-1Oguz, Aytekince3e3101-01ec-4709-ad5f-2ba54357481e-1Yusoff, Khalid933db13d-f5bb-4ea6-91a5-68eea1ca9ffc-1Zatonska, Katarzyna6d84170f-b69c-462b-9d93-3f363491580a-1Chifamba, Jephatf2496279-e934-40b8-8f61-0039a09f03f8-1Igumbor, Ehimario4c06c6fc-b069-45d4-91f6-19d0aa239652-1Mohan, Viswanathane7246d73-7de3-4d86-9c7b-b9ca011e618b-1Anjana, Ranjit Mohan8173cd60-0bc4-45b8-bd51-0d86cd38b382-1Gu, Hongqiu11ab896a-6bee-4073-b81d-babf5b57d28f-1Li, Wei16f14ef2-1a33-4354-93fe-e8d6d1ae09b7-1Yusuf, Salim06a836b5-f5e3-41d9-a516-9cc46e5d7948-1The PURE (Prospective Urban Rural Epidemiology) Study investigatorsed9b9e4f-c115-4708-b1ce-d8b43d622ddc-12019-08-06T16:28:00Z2019-08-06T16:28:00Z2015-078 p.Background Reduced muscular strength, as measured by grip strength, has been associated with an increased risk of all-cause and cardiovascular mortality. Grip strength is appealing as a simple, quick, and inexpensive means of stratifying an individual's risk of cardiovascular death. However, the prognostic value of grip strength with respect to the number and range of populations and confounders is unknown. The aim of this study was to assess the independent prognostic importance of grip strength measurement in socioculturally and economically diverse countries. Methods The Prospective Urban-Rural Epidemiology (PURE) study is a large, longitudinal population study done in 17 countries of varying incomes and sociocultural settings. We enrolled an unbiased sample of households, which were eligible if at least one household member was aged 35–70 years and if household members intended to stay at that address for another 4 years. Participants were assessed for grip strength, measured using a Jamar dynamometer. During a median follow-up of 4·0 years (IQR 2·9–5·1), we assessed all-cause mortality, cardiovascular mortality, non-cardiovascular mortality, myocardial infarction, stroke, diabetes, cancer, pneumonia, hospital admission for pneumonia or chronic obstructive pulmonary disease (COPD), hospital admission for any respiratory disease (including COPD, asthma, tuberculosis, and pneumonia), injury due to fall, and fracture. Study outcomes were adjudicated using source documents by a local investigator, and a subset were adjudicated centrally. Findings Between January, 2003, and December, 2009, a total of 142 861 participants were enrolled in the PURE study, of whom 139 691 with known vital status were included in the analysis. During a median follow-up of 4·0 years (IQR 2·9–5·1), 3379 (2%) of 139 691 participants died. After adjustment, the association between grip strength and each outcome, with the exceptions of cancer and hospital admission due to respiratory illness, was similar across country-income strata. Grip strength was inversely associated with all-cause mortality (hazard ratio per 5 kg reduction in grip strength 1·16, 95% CI 1·13–1·20; p<0·0001), cardiovascular mortality (1·17, 1·11–1·24; p<0·0001), non-cardiovascular mortality (1·17, 1·12–1·21; p<0·0001), myocardial infarction (1·07, 1·02–1·11; p=0·002), and stroke (1·09, 1·05–1·15; p<0·0001). Grip strength was a stronger predictor of all-cause and cardiovascular mortality than systolic blood pressure. We found no significant association between grip strength and incident diabetes, risk of hospital admission for pneumonia or COPD, injury from fall, or fracture. In high-income countries, the risk of cancer and grip strength were positively associated (0·916, 0·880–0·953; p<0·0001), but this association was not found in middle-income and low-income countries. Interpretation This study suggests that measurement of grip strength is a simple, inexpensive risk-stratifying method for all-cause death, cardiovascular death, and cardiovascular disease. Further research is needed to identify determinants of muscular strength and to test whether improvement in strength reduces mortality and cardiovascular disease. 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