Co-circulation and simultaneous co-infection of dengue, chikungunya, and zika viruses in patients with febrile syndrome at the Colombian-Venezuelan border
12 p.
- Autores:
-
Carrillo Hernández, Marlen Yelitza
Gómez Rangel, Sergio-Yebrail
Ruiz Saenz, Julian
Jaimes Villamizar, Lucy
Martínez Gutiérrez, Marlen
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2018
- Institución:
- Universidad de Santander
- Repositorio:
- Repositorio Universidad de Santander
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.udes.edu.co:001/3184
- Acceso en línea:
- https://repositorio.udes.edu.co/handle/001/3184
- Palabra clave:
- Dengue virus
Chikungunya virus
Zika virus
Co-infection
Co-circulation
- Rights
- openAccess
- License
- Derechos Reservados - Universidad de Santander, 2018
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Co-circulation and simultaneous co-infection of dengue, chikungunya, and zika viruses in patients with febrile syndrome at the Colombian-Venezuelan border |
| title |
Co-circulation and simultaneous co-infection of dengue, chikungunya, and zika viruses in patients with febrile syndrome at the Colombian-Venezuelan border |
| spellingShingle |
Co-circulation and simultaneous co-infection of dengue, chikungunya, and zika viruses in patients with febrile syndrome at the Colombian-Venezuelan border Dengue virus Chikungunya virus Zika virus Co-infection Co-circulation |
| title_short |
Co-circulation and simultaneous co-infection of dengue, chikungunya, and zika viruses in patients with febrile syndrome at the Colombian-Venezuelan border |
| title_full |
Co-circulation and simultaneous co-infection of dengue, chikungunya, and zika viruses in patients with febrile syndrome at the Colombian-Venezuelan border |
| title_fullStr |
Co-circulation and simultaneous co-infection of dengue, chikungunya, and zika viruses in patients with febrile syndrome at the Colombian-Venezuelan border |
| title_full_unstemmed |
Co-circulation and simultaneous co-infection of dengue, chikungunya, and zika viruses in patients with febrile syndrome at the Colombian-Venezuelan border |
| title_sort |
Co-circulation and simultaneous co-infection of dengue, chikungunya, and zika viruses in patients with febrile syndrome at the Colombian-Venezuelan border |
| dc.creator.fl_str_mv |
Carrillo Hernández, Marlen Yelitza Gómez Rangel, Sergio-Yebrail Ruiz Saenz, Julian Jaimes Villamizar, Lucy Martínez Gutiérrez, Marlen |
| dc.contributor.author.spa.fl_str_mv |
Carrillo Hernández, Marlen Yelitza Gómez Rangel, Sergio-Yebrail Ruiz Saenz, Julian Jaimes Villamizar, Lucy Martínez Gutiérrez, Marlen |
| dc.subject.proposal.spa.fl_str_mv |
Dengue virus Chikungunya virus Zika virus Co-infection Co-circulation |
| topic |
Dengue virus Chikungunya virus Zika virus Co-infection Co-circulation |
| description |
12 p. |
| publishDate |
2018 |
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2018-01-30 |
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2019-06-21T14:20:08Z |
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2019-06-21T14:20:08Z |
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Artículo de revista |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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10.1186/s12879-018-2976-1 |
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https://repositorio.udes.edu.co/handle/001/3184 |
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10.1186/s12879-018-2976-1 |
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https://repositorio.udes.edu.co/handle/001/3184 |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
| dc.relation.ispartof.spa.fl_str_mv |
BMC Infectious Diseases |
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Derechos Reservados - Universidad de Santander, 2018 |
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Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0) |
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https://creativecommons.org/licenses/by-nc/4.0/ |
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openAccess |
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application/pdf |
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Carrillo Hernández, Marlen Yelitzac6f08bd1-298b-4ad3-bf12-a33947ddf3e2-1Gómez Rangel, Sergio-Yebrail0347d3d7-298c-4b8a-a82b-e34275e1ea44-1Ruiz Saenz, Julian827f4fa2-52e4-40a5-b081-9e1d95950338-1Jaimes Villamizar, Lucy42cdc375-a833-45b9-ab35-585cb23ca6a1-1Martínez Gutiérrez, Marlen92bafe7d-5768-4f16-a861-1d5a7486c5bc-12019-06-21T14:20:08Z2019-06-21T14:20:08Z2018-01-3012 p.Background: In Colombia, the dengue virus (DENV) has been endemic for decades, and with the recent entry of the chikungunya virus (CHIKV) (2014) and the Zika virus (ZIKV) (2015), health systems are overloaded because the diagnosis of these three diseases is based on clinical symptoms, and the three diseases share a symptomatology of febrile syndrome. Thus, the objective of this study was to use molecular methods to identify their co-circulation as well as the prevalence of co-infections, in a cohort of patients at the Colombian-Venezuelan border. Methods: A total of 157 serum samples from patients with febrile syndrome consistent with DENV were collected after informed consent and processed for the identification of DENV (conventional PCR and real-time PCR), CHIKV (conventional PCR), and ZIKV (real-time PCR). DENV-positive samples were serotyped, and some of those positive for DENV and CHIKV were sequenced. Results: Eighty-two patients were positive for one or more viruses: 33 (21.02%) for DENV, 47 (29.94%) for CHIKV, and 29 (18.47%) for ZIKV. The mean age range of the infected population was statistically higher in the patients infected with ZIKV (29.72 years) than in those infected with DENV or CHIKV (21.09 years). Both co-circulation and coinfection of these three viruses was found. The prevalence of DENV/CHIKV, DENV/ZIKV, and CHIKV/ZIKV co-infection was 7.64%, 6.37%, and 5.10%, with attack rates of 14.90, 12.42, and 9.93 cases per 100,000 inhabitants, respectively. Furthermore, three patients were found to be co-infected with all three viruses (prevalence of 1.91%), with an attack rate of 4.96 cases per 100,000 inhabitants. Conclusion: Our results demonstrate the simultaneous co-circulation of DENV, CHIKV, ZIKV and their co-infections at the Colombian-Venezuelan border. Moreover, it is necessary to improve the differential diagnosis in patients with acute febrile syndrome and to study the possible consequences of this epidemiological overview of the clinical outcomes of these diseases in endemic regions.application/pdf10.1186/s12879-018-2976-1https://repositorio.udes.edu.co/handle/001/3184engBMC Infectious DiseasesDerechos Reservados - Universidad de Santander, 2018info:eu-repo/semantics/openAccessAtribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)https://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2https://bmcinfectdis.biomedcentral.com/track/pdf/10.1186/s12879-018-2976-1Dengue virusChikungunya virusZika virusCo-infectionCo-circulationCo-circulation and simultaneous co-infection of dengue, chikungunya, and zika viruses in patients with febrile syndrome at the Colombian-Venezuelan borderArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85PublicationTHUMBNAILCo-circulation and simultaneous co-infection of dengue, chikungunya, and zika viruses in patients with febrile syndrome at the Colombian-Venezuelan border.pdf.jpgCo-circulation and simultaneous co-infection of dengue, chikungunya, and zika viruses in patients with febrile syndrome at the Colombian-Venezuelan border.pdf.jpgGenerated Thumbnailimage/jpeg1631https://repositorio.udes.edu.co/bitstreams/b5496b11-d1a7-41b4-b9bd-c06f3def299e/download0219ff6045dfe137d37b14649387b0a5MD54TEXTCo-circulation and simultaneous co-infection of dengue, chikungunya, and zika viruses in patients with febrile syndrome at the Colombian-Venezuelan border.pdf.txtCo-circulation and simultaneous co-infection of dengue, chikungunya, and zika viruses in patients with febrile syndrome at the Colombian-Venezuelan border.pdf.txtExtracted texttext/plain62647https://repositorio.udes.edu.co/bitstreams/b7569c5c-2964-4a20-bfe7-e141e9def9e3/download2bab8b42460f04167042f1057c2e60c5MD53LICENSElicense.txtlicense.txttext/plain; charset=utf-859https://repositorio.udes.edu.co/bitstreams/894138be-4f42-48cf-b1ad-5b2572502ec1/download38d94cf55aa1bf2dac1a736ac45c881cMD52ORIGINALCo-circulation and simultaneous co-infection of dengue, chikungunya, and zika viruses in patients with febrile syndrome at the Colombian-Venezuelan border.pdfCo-circulation and simultaneous co-infection of dengue, chikungunya, and zika viruses in patients with febrile syndrome at the Colombian-Venezuelan border.pdfDocumento Principalapplication/pdf632504https://repositorio.udes.edu.co/bitstreams/d7ffbcf1-b612-455e-b603-45cc2801e248/download92a24eacb1aab1367ae79ccee98bfdf2MD51001/3184oai:repositorio.udes.edu.co:001/31842023-10-10 09:48:34.176https://creativecommons.org/licenses/by-nc/4.0/Derechos Reservados - Universidad de Santander, 2018https://repositorio.udes.edu.coRepositorio Universidad de Santandersoporte@metabiblioteca.comTGljZW5jaWEgZGUgUHVibGljYWNpw7NuIFVERVMKRGlyZWN0cmljZXMgZGUgVVNPIHkgQUNDRVNPCgo= |