Seroprevalencia de Toxoplasma gondii en Gatos y Factores de Riesgo en Clínicas Veterinarias de Bucaramanga y su Área Metropolitana

Digital

Autores:: Coronel-Rueda, Juan José
Sandoval-Basto, Nathalia Valentina

Tipo de recurso:: Trabajo de grado de pregrado

Fecha de publicación:: 2023

Institución:: Universidad de Santander

Repositorio:: Repositorio Universidad de Santander

Idioma:: spa

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dc.title.none.fl_str_mv	Seroprevalencia de Toxoplasma gondii en Gatos y Factores de Riesgo en Clínicas Veterinarias de Bucaramanga y su Área Metropolitana
dc.title.translated.none.fl_str_mv	Seroprevalence and Risk Factors of Toxoplasma gondii in Cats From Clinics in the Metropolitan Area of Bucaramanga
title	Seroprevalencia de Toxoplasma gondii en Gatos y Factores de Riesgo en Clínicas Veterinarias de Bucaramanga y su Área Metropolitana
spellingShingle	Seroprevalencia de Toxoplasma gondii en Gatos y Factores de Riesgo en Clínicas Veterinarias de Bucaramanga y su Área Metropolitana Epidemiología ELISA Factores de Riesgo Toxoplasma gondii Gatos Cats Epidemiology ELISA Risk Factors Toxoplasma gondii
title_short	Seroprevalencia de Toxoplasma gondii en Gatos y Factores de Riesgo en Clínicas Veterinarias de Bucaramanga y su Área Metropolitana
title_full	Seroprevalencia de Toxoplasma gondii en Gatos y Factores de Riesgo en Clínicas Veterinarias de Bucaramanga y su Área Metropolitana
title_fullStr	Seroprevalencia de Toxoplasma gondii en Gatos y Factores de Riesgo en Clínicas Veterinarias de Bucaramanga y su Área Metropolitana
title_full_unstemmed	Seroprevalencia de Toxoplasma gondii en Gatos y Factores de Riesgo en Clínicas Veterinarias de Bucaramanga y su Área Metropolitana
title_sort	Seroprevalencia de Toxoplasma gondii en Gatos y Factores de Riesgo en Clínicas Veterinarias de Bucaramanga y su Área Metropolitana
dc.creator.fl_str_mv	Coronel-Rueda, Juan José Sandoval-Basto, Nathalia Valentina
dc.contributor.advisor.none.fl_str_mv	Goyeneche-Patiño, Diego Andrés
dc.contributor.author.none.fl_str_mv	Coronel-Rueda, Juan José Sandoval-Basto, Nathalia Valentina
dc.contributor.jury.none.fl_str_mv	Barrera-Rivera, Jennifer Andrea Espinel-Mesa, Denerieth Ximena
dc.contributor.researchgroup.none.fl_str_mv	INMUNO-INFECTO
dc.subject.proposal.spa.fl_str_mv	Epidemiología ELISA Factores de Riesgo Toxoplasma gondii Gatos
topic	Epidemiología ELISA Factores de Riesgo Toxoplasma gondii Gatos Cats Epidemiology ELISA Risk Factors Toxoplasma gondii
dc.subject.proposal.eng.fl_str_mv	Cats Epidemiology ELISA Risk Factors Toxoplasma gondii
description	Digital
publishDate	2023
dc.date.issued.none.fl_str_mv	2023-11-27
dc.date.accessioned.none.fl_str_mv	2024-03-01T21:14:03Z
dc.date.available.none.fl_str_mv	2024-03-01T21:14:03Z
dc.type.none.fl_str_mv	Trabajo de grado - Pregrado
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dc.relation.references.none.fl_str_mv	Al-Kappany, Y. M., Abbas, I. E., Devleesschauwer, B., Dorny, P., Jennes, M., & Cox, E. (2018). Seroprevalence of anti-Toxoplasma gondii Antibodies in Egyptian Sheep and Goats. BMC Veterinary Research, 14(1), 120. https://doi.org/10.1186/s12917-018-1440-1 Angel-Müller, E., Hougton, M. P., Eslava, C., Riaño, J., Rey, G. E., & Gómez-Marín, J. E. (2014). Gestational and Congenital Toxoplasmosis in two Hospitals in Bogota, Colombia. Revista de La Facultad de Medicina, 62(2), 179-185. https://doi.org/10.15446/revfacmed.v62n2.45430 Barbosa da Silva, J., Nunes de Santana Castro, G., Nunes dos Santos, P., Henrique da Fonseca, A., Henrique da Silva Lima, D., dos Anjos Bomjardim, H., dos Santos Belo Reis, A., de Oliveira Soares, S., & Diomedes Barbosa, J. (2015). Detection of a High Prevalence of Antibodies Against Toxoplasma Gondii in Cattle in Northern and Midwestern Brazil. Revista de Salud Animal, 37, 52-56. Boughattas, S., Behnke, J., Sharma, A., & Abu-Madi, M. (2017). Seroprevalence of Toxoplasma gondii Infection in Feral Cats in Qatar. BMC Veterinary Research, 13(1), 26. https://doi.org/10.1186/s12917-017-0952-4 Calero-Bernal, R., & Gennari, S. M. (2019). Clinical Toxoplasmosis in Dogs and Cats: An Update. Frontiers in Veterinary Science, 6, 54. https://doi.org/10.3389/fvets.2019.00054 Cañón-Franco, W. A., López-Orozco, N., Gómez-Marín, J. E., & Dubey, J. P. (2014). An Overview of Seventy Years of Research (1944 – 2014) on Toxoplasmosis in Colombia, South America. Parasites & Vectors, 7(1), 427. https://doi.org/10.1186/1756-3305-7-427 Carlos Betancur & Juan Jaramillo. (2011). Seroprevalencia de Toxoplasmosis en Donantes de Sangre de la Clínica Cardiovascular Santa María, Medellín, Colombia, 2009-2010 \| Elsevier Enhanced Reader. https://doi.org/10.1016/S0123-9392(11)70071-6 Castillo-Morales, V. J., Acosta Viana, K. Y., Guzmán-Marín, E. D. S., Jiménez-Coello, M., Segura-Correa, J. C., Aguilar-Caballero, A. J., & Ortega-Pacheco, A. (2012). Prevalence and Risk Factors of Toxoplasma gondii Infection in Domestic Cats From the Tropics of Mexico Using Serological and Molecular Tests. Interdisciplinary Perspectives on Infectious Diseases, 2012, 1-6. https://doi.org/10.1155/2012/529108 Castro, A. T., Góngora, A., & González, M. E. (2008). Seroprevalencia de Anticuerpos a Toxoplasma Gondii en Mujeres Embarazadas de Villavicencio, Colombia. Orinoquia, 12(1), 91-100. Cavalcante, G. T., Aguiar, D. M., Chiebao, D., Dubey, J. P., Ruiz, V. L. A., Dias, R. A., Camargo, L. M. A., Labruna, M. B., & Gennari, S. M. (2006). Seroprevalence of Toxoplasma gondii Antibodies in Cats and Pigs From Rural Western Amazon, Brazil. The Journal of Parasitology, 92(4), 863-864. https://doi.org/10.1645/GE-830R.1 Cruz, M. D. A., Ullmann, L. S., Montaño, P. Y., Hoffmann, J. L., Langoni, H., & Biondo, A. W. (2011). Seroprevalence of Toxoplasma gondii Infection in Cats From Curitiba, Paraná, Brazil. Revista Brasileira de Parasitologia Veterinária, 20(3), 256-258. https://doi.org/10.1590/S1984-29612011000300016 Dubey, J. P., Su, C., Cortés, J. A., Sundar, N., Gomez-Marin, J. E., Polo, L. J., Zambrano, L., Mora, L. E., Lora, F., Jimenez, J., Kwok, O. C. H., Shen, S. K., Zhang, X., Nieto, A., & Thulliez, P. (2006). Prevalence of Toxoplasma gondii in Cats From Colombia, South America and Genetic Characterization of T. gondii Isolates. Veterinary Parasitology, 141(1-2), 42-47. https://doi.org/10.1016/j.vetpar.2006.04.037 Elmore, S. A., Jones, J. L., Conrad, P. A., Patton, S., Lindsay, D. S., & Dubey, J. P. (2010). Toxoplasma gondii: Epidemiology, Feline Clinical Aspects, and Prevention. Trends in Parasitology, 26(4), 190-196. https://doi.org/10.1016/j.pt.2010.01.009 Espinosa, Torres, & Alzate. (2011). Prevalencia de Toxoplasma gondii en Gatos Domésticos del Casco Urbano del Municipio de Florencia-Caquéta. Franco-Hernandez, E. N., Acosta, A., Cortés-Vecino, J., & Gómez-Marín, J. E. (2016). Survey for Toxoplasma gondii by PCR Detection in Meat for Human Consumption in Colombia. Parasitology Research, 115(2), 691-695. https://doi.org/10.1007/s00436-015-4790-7 Greene. (2022). Infectious Diseases of the Dog and Cat 5th Edition. Hammond-Aryee, K., Esser, M., van Helden, L., & van Helden, P. (2015). A high Seroprevalence of Toxoplasma Gondii Antibodies in a Population of Feral Cats in the Western Cape province of South Africa. Southern African Journal of Infectious Diseases, 30(4), 141-144. https://doi.org/10.1080/23120053.2015.1107295 Hill, D., & Dubey, J. P. (2002). Toxoplasma gondii: Transmission, Diagnosis and Prevention. Clinical Microbiology and Infection, 8(10), 634-640. https://doi.org/10.1046/j.1469- 0691.2002.00485.x Jones, J., Lopez, A., & Wilson, M. (2003). Congenital Toxoplasmosis. American Family Physician, 67(10), 2131-2138. Kim, Y. H., Lee, J. hoo, Ahn, S. kyu, Kim, T.-S., Hong, S.-J., Chong, C.-K., Ahn, H.-J., & Nam, H.-W. (2017). Seroprevalence of Toxoplasmosis With ELISA and Rapid Diagnostic Test Among Residents in Gyodong-do, Inchon city, Korea: A Four-Year Follow-up. The Korean Journal of Parasitology, 55(3), 247-254. https://doi.org/10.3347/kjp.2017.55.3.247 Liu, Q., Wang, Z.-D., Huang, S.-Y., & Zhu, X.-Q. (2015). Diagnosis of Toxoplasmosis and Typing of Toxoplasma gondii. Parasites & Vectors, 8. https://doi.org/10.1186/s13071- 015-0902-6 Must, K., Lassen, B., & Jokelainen, P. (2015). Seroprevalence of and Risk Factors for Toxoplasma gondii Infection in Cats in Estonia. Vector-Borne and Zoonotic Diseases, 15(10), 597-601. https://doi.org/10.1089/vbz.2015.1809 Opsteegh, M., Haveman, R., Swart, A. N., Mensink-Beerepoot, M. E., Hofhuis, A., Langelaar, M. F. M., & van der Giessen, J. W. B. (2012). Seroprevalence and Risk Factors for Toxoplasma gondii Infection in Domestic cats in The Netherlands. Preventive Veterinary Medicine, 104(3), 317-326. https://doi.org/10.1016/j.prevetmed.2012.01.003 Petersen, E., & Dubey, J. P. (2001). Biology of toxoplasmosis. En D. H. M. Joynson & T. G. Wreghitt (Eds.), Toxoplasmosis (1.a ed., pp. 1-42). Cambridge University Press. https://doi.org/10.1017/CBO9780511527005.003 Rosso, F., Les, J. T., Agudelo, A., Villalobos, C., Chaves, J. A., Tunubala, G. A., Messa, A., Remington, J. S., & Montoya, J. G. (2008). Prevalence of Infection With Toxoplasma gondii among pregnant women in Cali, Colombia, South America. The American Journal of Tropical Medicine and Hygiene, 78(3), 504-508. Sharifdini, M., Mohebali, M., Keshavarz, H., Hosseininejad, M., Hajjaran, H., Akhoundi, B., Rahimi Foroushani, A., & Zarei, Z. (2016a). Seroprevalence of Toxoplasma gondii Infection in Domestic dogs in an Area From northwest of Iran: A Cross-Sectional Study Using Immunodominant Surface Antigen 1 (SAG1). Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology, 40(4), 1278-1282. https://doi.org/10.1007/s12639-015-0667-z Sharifdini, M., Mohebali, M., Keshavarz, H., Hosseininejad, M., Hajjaran, H., Akhoundi, B., Rahimi Foroushani, A., & Zarei, Z. (2016b). Seroprevalence of Toxoplasma gondii Infection in Domestic Dogs in an area From Northwest of Iran: A Cross-Sectional Study Using Immunodominant Surface Antigen 1 (SAG1). Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology, 40(4), 1278-1282. https://doi.org/10.1007/s12639-015-0667-z Sroka, J., Karamon, J., Dutkiewicz, J., Wójcik Fatla, A., Zając, V., & Cencek, T. (2018). Prevalence of Toxoplasma gondii Infection in Cats in Southwestern Poland. Annals of Agricultural and Environmental Medicine: AAEM, 25(3), 576-580. https://doi.org/10.26444/aaem/94675 Switzer, A. D., McMillan-Cole, A. C., Kasten, R. W., Stuckey, M. J., Kass, P. H., & Chomel, B. B. (2013). Bartonella and Toxoplasma Infections in Stray Cats from Iraq. The American Journal of Tropical Medicine and Hygiene, 89(6), 1219-1224. https://doi.org/10.4269/ajtmh.13-0353 Tiao, N., Darrington, C., Molla, B., Saville, W. J. A., Tilahun, G., Kwok, O. C. H., Gebreyes, W. A., Lappin, M. R., Jones, J. L., & Dubey, J. P. (2013). An Investigation Into the Seroprevalence of Toxoplasma gondii, Bartonella spp., Feline Immunodeficiency Virus (FIV), and Feline Leukaemia Virus (FeLV) in Cats in Addis Ababa, Ethiopia. Epidemiology and Infection, 141(5), 1029-1033. https://doi.org/10.1017/S0950268812001707 Wilking, H., Thamm, M., Stark, K., Aebischer, T., & Seeber, F. (2016). Prevalence, Incidence Estimations and Risk Factors of Toxoplasma gondii Infection in Germany: A Representative, Cross-Sectional, Serological study. Scientific Reports, 6(1), 22551. https://doi.org/10.1038/srep22551 Zhou, P., Chen, Z., Li, H.-L., Zheng, H., He, S., Lin, R.-Q., & Zhu, X.-Q. (2011). Toxoplasma gondii Infection in Humans in China. Parasites & Vectors, 4(1), 165. https://doi.org/10.1186/1756-3305-4-165 Zhou, S., Sang, Z., Wang, L., & Zhang, T. (2022). Seroprevalence of Toxoplasma gondii in Cats in Mainland China 2016–2020: A Meta-Analysis. Journal of Veterinary Science, 23(1), e13. https://doi.org/10.4142/jvs.21209
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dc.publisher.none.fl_str_mv	Universidad de Santander
dc.publisher.branch.none.fl_str_mv	Bucaramanga
dc.publisher.faculty.none.fl_str_mv	Facultad de Ciencias Agrícolas y Veterinarias
dc.publisher.place.none.fl_str_mv	Bucaramanga, Colombia
dc.publisher.program.none.fl_str_mv	Medicina Veterinaria
publisher.none.fl_str_mv	Universidad de Santander
institution	Universidad de Santander
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spelling	Goyeneche-Patiño, Diego Andrésa8bf4ff9-b599-4e6f-bf50-6e4876780359-1Coronel-Rueda, Juan José083ff5ac-000a-4c71-8ebc-1d9cc29157f3-1Sandoval-Basto, Nathalia Valentina2c20d4c0-1624-4989-8448-4c58dcedfca3-1Barrera-Rivera, Jennifer Andreaae7cf9ea-eed2-4c52-92db-5590b9f2009a-1Espinel-Mesa, Denerieth Ximena3cd09d17-3f8c-4727-b7a0-36a51dcd2745600INMUNO-INFECTO2024-03-01T21:14:03Z2024-03-01T21:14:03Z2023-11-27DigitalAntecedentes: La toxoplasmosis se transmite por contacto directo del humano con la materia fecal de gatos, fómites o alimentos contaminados. Se recopilaron datos sobre seroprevalencia de T. gondii en gatos domésticos y felinos salvajes a nivel mundial donde la seroprevalencia general fue 35% y la prevalencia en Suramérica fue del 37% en gatos domésticos y 66% en felinos salvajes. Un estudio del eje cafetero colombiano obtuvo una prevalencia de 52.7% en humanos y se informa que los FR asociados son la interacción de gatos domésticos con callejeros, el consumo de dieta con carne cruda y la caza. Objetivo: Determinar la seroprevalencia y FR asociados a la presentación de T. gondii en gatos de clínicas del área metropolitana de Bucaramanga. Metodología: Se realizó un estudio descriptivo de corte transversal, se tomó sangre a 334 gatos de clínicas de Piedecuesta, Floridablanca, Bucaramanga y Girón. Los sueros se analizaron mediante ELISA indirecto del kit ID Screen Toxoplasmosis Indirect Multi species. Mediante una encuesta se obtuvieron datos poblacionales y de manejo para identificar posibles FR. Los resultados se analizaron con prueba de chi cuadrado. Resultados: La prevalencia general de T. gondii fue 14,97%, el resultado por ciudad fue 10,04% Piedecuesta, 10,05% Floridablanca, 15,27% Bucaramanga y 38,70% Girón. Hubo asociaciones estadísticamente significativas entre la seropositividad y variables con resultados OR como albergue 11,67, gatos callejeros 24,95, consumo de comida no comercial 3,52, gatos cazadores 3,82, gatos que defecan en la calle 16,22, limpieza del arenero una vez por semana 5,65 y gatos enteros 5,82. Conclusiones: La seroprevalencia general de T. gondii fue del 14,97% en el área metropolitana de Bucaramanga, y Girón es el municipio con el resultado más alto. Se evidenció las variables asociadas a la presentación y predisposición a infectarse con T. gondii.Background: Toxoplasmosis is transmitted by direct human contact with cat fecal matter, fomites or contaminated food. Data on seroprevalence of T. gondii in domestic cats and wild felids were collected worldwide where the overall seroprevalence was 35% and the prevalence in South America was 37% in domestic cats and 66% in wild felids. A study in the Colombian coffee region obtained a prevalence of 52.7% in humans and it is reported that the associated RFs are the interaction of domestic cats with strays, the consumption of a diet with raw meat and hunting. Objective: Determine the seroprevalence and RF associated with the presentation of T. gondii in cats from clinics in the metropolitan area of Bucaramanga. Methodology: A descriptive cross-sectional study was carried out, blood was taken from 334 cats from clinics in Piedecuesta, Floridablanca, Bucaramanga and Girón. The sera were analyzed by indirect ELISA of the ID Screen Toxoplasmosis Indirect Multi species kit. Through a survey, population and management data were obtained to identify possible RFs. The results were analyzed with the chi square test. Results: The general prevalence of T. gondii was 14.97%, the result by city was 10.04% Piedecuesta, 10.05% Floridablanca, 15.27% Bucaramanga and 38.70% Girón. There were statistically significant associations between seropositivity and variables with OR results such as shelter 11.67, stray cats 24.95, consumption of non-commercial food 3.52, hunting cats 3.82, cats that defecate in the street 16.22, cleanliness from the litter box once a week 5.65 and whole cats 5.82. Conclusions: The general seroprevalence of T. gondii was 14.97% in the metropolitan area of Bucaramanga, and Girón is the municipality with the highest result. The variables associated with the presentation and predisposition to be infected with T. gondii were evident.PregradoMédico VeterinarioEstudio Descriptivo de Corte TransversalIntroducción 19 Planteamiento del Problema 23 Pregunta de Investigación 27 Justificación 28 Objetivos 34 Objetivo General 34 Objetivos Específicos 34 Marco Teórico 35 Ciclo de Vida 35 Hallazgos Clínicos en la Toxoplasmosis Felina 37 Epidemiología y Factores de Riegos 38 Toxoplasmosis en Humanos 39 Diagnostico Serológico de Toxoplasma gondii 39 Tratamiento de la Toxoplasmosis en Gatos 40 Materiales y Métodos 41 Diseño y Población de Estudio 41 Recolección de la Muestra 41 Recolección de la Información Epidemiológica 41 ELISA para la Determinación de Anticuerpos Anti-T. gondii 42 Análisis Estadístico 42 Consideraciones Éticas 43 Resultados 44 Descripción de la Población 44 Seroprevalencia de Toxoplasma gondii 44 Determinación de Factores de Riesgo 46 Discusión 50 Conclusiones 54 Referencias Bibliográficas 57 Apéndices 6369 papplication/pdfapplication/mswordapplication/vnd.ms-powerpointUniversidad de SantanderT 35.23 C676sRepositorio Digital Institucional Universidad de Santanderhttps://repositorio.udes.edu.cohttps://repositorio.udes.edu.co/handle/001/10054spaUniversidad de SantanderBucaramangaFacultad de Ciencias Agrícolas y VeterinariasBucaramanga, ColombiaMedicina VeterinariaAl-Kappany, Y. 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Al consultar y hacer uso de este recurso, está aceptando las condiciones de uso establecidas por los autores.https://repositorio.udes.edu.coRepositorio Universidad de 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

Seroprevalencia de Toxoplasma gondii en Gatos y Factores de Riesgo en Clínicas Veterinarias de Bucaramanga y su Área Metropolitana

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