Electroconvulsive Therapy in Psychiatric Disorders: A Narrative Review Exploring Neuroendocrine–Immune Therapeutic Mechanisms and Clinical Implications
Digital
- Autores:
-
Rojas, Milagros
Ariza, Daniela
Ortega, Angel
Riano-Garzon, Manuel E.
Chavez-Castillo, Mervin
Perez, Jose Luis
Cudris-Torres, Lorena
Bautista, María Judith
Medina-Ortiz, Oscar
Rojas-Quintero, Joselyn
Bermudez, Valmore
- Tipo de recurso:
- Review article
- Fecha de publicación:
- 2022
- Institución:
- Universidad de Santander
- Repositorio:
- Repositorio Universidad de Santander
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.udes.edu.co:001/7339
- Acceso en línea:
- https://doi.org/10.3390/ijms23136918
https://repositorio.udes.edu.co/handle/001/7339
- Palabra clave:
- Electroconvulsive Therapy
Mood Disorders
Neuroinflammatory Diseases
Neurogenesis
Neurotransmitter Agents
Hippocampus
Refractory Depression
Schizophrenia
- Rights
- openAccess
- License
- © 1996-2022 The Authors, MDPI (Basel, Switzerland) unless otherwise stated
| id |
RUDES2_8666122ff92d19e0fc78729d705ac133 |
|---|---|
| oai_identifier_str |
oai:repositorio.udes.edu.co:001/7339 |
| network_acronym_str |
RUDES2 |
| network_name_str |
Repositorio Universidad de Santander |
| repository_id_str |
|
| dc.title.spa.fl_str_mv |
Electroconvulsive Therapy in Psychiatric Disorders: A Narrative Review Exploring Neuroendocrine–Immune Therapeutic Mechanisms and Clinical Implications |
| title |
Electroconvulsive Therapy in Psychiatric Disorders: A Narrative Review Exploring Neuroendocrine–Immune Therapeutic Mechanisms and Clinical Implications |
| spellingShingle |
Electroconvulsive Therapy in Psychiatric Disorders: A Narrative Review Exploring Neuroendocrine–Immune Therapeutic Mechanisms and Clinical Implications Electroconvulsive Therapy Mood Disorders Neuroinflammatory Diseases Neurogenesis Neurotransmitter Agents Hippocampus Refractory Depression Schizophrenia |
| title_short |
Electroconvulsive Therapy in Psychiatric Disorders: A Narrative Review Exploring Neuroendocrine–Immune Therapeutic Mechanisms and Clinical Implications |
| title_full |
Electroconvulsive Therapy in Psychiatric Disorders: A Narrative Review Exploring Neuroendocrine–Immune Therapeutic Mechanisms and Clinical Implications |
| title_fullStr |
Electroconvulsive Therapy in Psychiatric Disorders: A Narrative Review Exploring Neuroendocrine–Immune Therapeutic Mechanisms and Clinical Implications |
| title_full_unstemmed |
Electroconvulsive Therapy in Psychiatric Disorders: A Narrative Review Exploring Neuroendocrine–Immune Therapeutic Mechanisms and Clinical Implications |
| title_sort |
Electroconvulsive Therapy in Psychiatric Disorders: A Narrative Review Exploring Neuroendocrine–Immune Therapeutic Mechanisms and Clinical Implications |
| dc.creator.fl_str_mv |
Rojas, Milagros Ariza, Daniela Ortega, Angel Riano-Garzon, Manuel E. Chavez-Castillo, Mervin Perez, Jose Luis Cudris-Torres, Lorena Bautista, María Judith Medina-Ortiz, Oscar Rojas-Quintero, Joselyn Bermudez, Valmore |
| dc.contributor.author.none.fl_str_mv |
Rojas, Milagros Ariza, Daniela Ortega, Angel Riano-Garzon, Manuel E. Chavez-Castillo, Mervin Perez, Jose Luis Cudris-Torres, Lorena Bautista, María Judith Medina-Ortiz, Oscar Rojas-Quintero, Joselyn Bermudez, Valmore |
| dc.contributor.researchgroup.spa.fl_str_mv |
Entropia |
| dc.subject.proposal.eng.fl_str_mv |
Electroconvulsive Therapy Mood Disorders Neuroinflammatory Diseases Neurogenesis Neurotransmitter Agents Hippocampus Refractory Depression |
| topic |
Electroconvulsive Therapy Mood Disorders Neuroinflammatory Diseases Neurogenesis Neurotransmitter Agents Hippocampus Refractory Depression Schizophrenia |
| dc.subject.proposal.spa.fl_str_mv |
Schizophrenia |
| description |
Digital |
| publishDate |
2022 |
| dc.date.accessioned.none.fl_str_mv |
2022-08-03T22:29:27Z |
| dc.date.available.none.fl_str_mv |
2022-08-03T22:29:27Z |
| dc.date.issued.none.fl_str_mv |
2022-06-22 |
| dc.type.spa.fl_str_mv |
Artículo de revista |
| dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
| dc.type.coarversion.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_dcae04bc |
| dc.type.content.spa.fl_str_mv |
Text |
| dc.type.driver.spa.fl_str_mv |
info:eu-repo/semantics/article |
| dc.type.redcol.spa.fl_str_mv |
http://purl.org/redcol/resource_type/ARTREV |
| dc.type.version.spa.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| format |
http://purl.org/coar/resource_type/c_dcae04bc |
| status_str |
publishedVersion |
| dc.identifier.doi.none.fl_str_mv |
https://doi.org/10.3390/ijms23136918 |
| dc.identifier.issn.spa.fl_str_mv |
1422-0067 |
| dc.identifier.uri.none.fl_str_mv |
https://repositorio.udes.edu.co/handle/001/7339 |
| url |
https://doi.org/10.3390/ijms23136918 https://repositorio.udes.edu.co/handle/001/7339 |
| identifier_str_mv |
1422-0067 |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
| dc.relation.citationendpage.spa.fl_str_mv |
26 |
| dc.relation.citationissue.spa.fl_str_mv |
13 |
| dc.relation.citationstartpage.spa.fl_str_mv |
1 |
| dc.relation.citationvolume.spa.fl_str_mv |
23 |
| dc.relation.cites.none.fl_str_mv |
Rojas, M.; Ariza, D.; Ortega, Á.; Riaño-Garzón, M.E.; Chávez-Castillo, M.; Pérez, J.L.; Cudris-Torres, L.; Bautista, M.J.; Medina-Ortiz, O.; Rojas-Quintero, J.; Bermúdez, V. Electroconvulsive Therapy in Psychiatric Disorders: A Narrative Review Exploring Neuroendocrine–Immune Therapeutic Mechanisms and Clinical Implications. Int. J. Mol. Sci. 2022, 23, 6918. https://doi.org/10.3390/ijms23136918 |
| dc.relation.indexed.spa.fl_str_mv |
Scopus |
| dc.relation.ispartofjournal.spa.fl_str_mv |
International Journal of Molecular Sciences |
| dc.rights.spa.fl_str_mv |
© 1996-2022 The Authors, MDPI (Basel, Switzerland) unless otherwise stated |
| dc.rights.coar.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
| dc.rights.accessrights.spa.fl_str_mv |
info:eu-repo/semantics/openAccess |
| dc.rights.creativecommons.spa.fl_str_mv |
Atribución 4.0 Internacional (CC BY 4.0) |
| dc.rights.uri.spa.fl_str_mv |
https://creativecommons.org/licenses/by/4.0/ |
| rights_invalid_str_mv |
© 1996-2022 The Authors, MDPI (Basel, Switzerland) unless otherwise stated Atribución 4.0 Internacional (CC BY 4.0) https://creativecommons.org/licenses/by/4.0/ http://purl.org/coar/access_right/c_abf2 |
| eu_rights_str_mv |
openAccess |
| dc.format.extent.spa.fl_str_mv |
26 p |
| dc.format.mimetype.spa.fl_str_mv |
application/pdf |
| dc.publisher.place.spa.fl_str_mv |
Suiza |
| dc.source.spa.fl_str_mv |
https://www.mdpi.com/1422-0067/23/13/6918 |
| institution |
Universidad de Santander |
| bitstream.url.fl_str_mv |
https://repositorio.udes.edu.co/bitstreams/fc124baa-2784-4979-8858-38645668eacf/download https://repositorio.udes.edu.co/bitstreams/72a03aa7-1a63-4c5d-9899-c042ae7e7c77/download https://repositorio.udes.edu.co/bitstreams/a582f4fc-4535-4b9b-b98c-ab7bd2ebc2e2/download https://repositorio.udes.edu.co/bitstreams/df7de5bd-5f48-4af0-9569-dd071689f109/download |
| bitstream.checksum.fl_str_mv |
5a636364e5a525ee7410a00ff5c27cec 38d94cf55aa1bf2dac1a736ac45c881c b8124d19071d0062087712797db2c1a7 d5b8f4cf0d5e3311ce36554e90425628 |
| bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 |
| repository.name.fl_str_mv |
Repositorio Universidad de Santander |
| repository.mail.fl_str_mv |
soporte@metabiblioteca.com |
| _version_ |
1814158550870523904 |
| spelling |
Rojas, Milagrosea9e3f51-9796-4f19-a3c8-8e9dd889c4ec-1Ariza, Daniela80425a51-dfdd-4da7-a3f3-984f08bec0de-1Ortega, Angel1ab36631-a9d0-4944-887a-f35d8f7a9860-1Riano-Garzon, Manuel E.825e35e3-2769-40f0-8b0c-b04ae1fe980b-1Chavez-Castillo, Mervin0c55fb94-d695-4061-9965-5c45c96ada9e-1Perez, Jose Luis9bd0ad49-9bfc-4895-bb6b-91b2b12dbf5a-1Cudris-Torres, Lorena98991772-8876-42f0-9d35-99ff389b3718-1Bautista, María Judith038bb61c-51c0-4d2f-8f46-dbe3cd3cbac5-1Medina-Ortiz, Oscardd64d41b-e13a-4ce9-b1d6-62245e46857a-1Rojas-Quintero, Joselyn180f5ac3-6fb0-4313-8d93-9d7e8a12b995-1Bermudez, Valmore1290aa1d-6b03-4912-aff2-b6c85a9f2378-1Entropia2022-08-03T22:29:27Z2022-08-03T22:29:27Z2022-06-22DigitalElectroconvulsive therapy (ECT) is based on conducting an electrical current through the brain to stimulate it and trigger generalized convulsion activity with therapeutic ends. Due to the efficient use of ECT during the last years, interest in the molecular bases involved in its mechanism of action has increased. Therefore, different hypotheses have emerged. In this context, the goal of this review is to describe the neurobiological, endocrine, and immune mechanisms involved in ECT and to detail its clinical efficacy in different psychiatric pathologies. This is a narrative review in which an extensive literature search was performed on the Scopus, Embase, PubMed, ISI Web of Science, and Google Scholar databases from inception to February 2022. The terms “electroconvulsive therapy”, “neurobiological effects of electroconvulsive therapy”, “molecular mechanisms in electroconvulsive therapy”, and “psychiatric disorders” were among the keywords used in the search. The mechanisms of action of ECT include neurobiological function modifications and endocrine and immune changes that take place after ECT. Among these, the decrease in neural network hyperconnectivity, neuroinflammation reduction, neurogenesis promotion, modulation of different monoaminergic systems, and hypothalamus–hypophysis–adrenal and hypothalamus–hypophysis–thyroid axes normalization have been described. The majority of these elements are physiopathological components and therapeutic targets in different mental illnesses. Likewise, the use of ECT has recently expanded, with evidence of its use for other pathologies, such as Parkinson’s disease psychosis, malignant neuroleptic syndrome, post-traumatic stress disorder, and obsessive–compulsive disorder. In conclusion, there is sufficient evidence to support the efficacy of ECT in the treatment of different psychiatric disorders, potentially through immune, endocrine, and neurobiological systemsCiencias Médicas y de la Salud26 papplication/pdfhttps://doi.org/10.3390/ijms231369181422-0067https://repositorio.udes.edu.co/handle/001/7339engSuiza2613123Rojas, M.; Ariza, D.; Ortega, Á.; Riaño-Garzón, M.E.; Chávez-Castillo, M.; Pérez, J.L.; Cudris-Torres, L.; Bautista, M.J.; Medina-Ortiz, O.; Rojas-Quintero, J.; Bermúdez, V. Electroconvulsive Therapy in Psychiatric Disorders: A Narrative Review Exploring Neuroendocrine–Immune Therapeutic Mechanisms and Clinical Implications. Int. J. Mol. Sci. 2022, 23, 6918. https://doi.org/10.3390/ijms23136918ScopusInternational Journal of Molecular Sciences© 1996-2022 The Authors, MDPI (Basel, Switzerland) unless otherwise statedinfo:eu-repo/semantics/openAccessAtribución 4.0 Internacional (CC BY 4.0)https://creativecommons.org/licenses/by/4.0/http://purl.org/coar/access_right/c_abf2https://www.mdpi.com/1422-0067/23/13/6918Electroconvulsive TherapyMood DisordersNeuroinflammatory DiseasesNeurogenesisNeurotransmitter AgentsHippocampusRefractory DepressionSchizophreniaElectroconvulsive Therapy in Psychiatric Disorders: A Narrative Review Exploring Neuroendocrine–Immune Therapeutic Mechanisms and Clinical ImplicationsArtículo de revistahttp://purl.org/coar/resource_type/c_dcae04bchttp://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTREVinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85Todas las AudienciasPublicationORIGINALElectroconvulsive Therapy in Psychiatric Disorders. A Narrative Review Exploring Neuroendocrine–Immune Therapeutic Mechanisms and Clinical Implications.pdfElectroconvulsive Therapy in Psychiatric Disorders. A Narrative Review Exploring Neuroendocrine–Immune Therapeutic Mechanisms and Clinical Implications.pdfapplication/pdf288420https://repositorio.udes.edu.co/bitstreams/fc124baa-2784-4979-8858-38645668eacf/download5a636364e5a525ee7410a00ff5c27cecMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-859https://repositorio.udes.edu.co/bitstreams/72a03aa7-1a63-4c5d-9899-c042ae7e7c77/download38d94cf55aa1bf2dac1a736ac45c881cMD52TEXTElectroconvulsive Therapy in Psychiatric Disorders. A Narrative Review Exploring Neuroendocrine–Immune Therapeutic Mechanisms and Clinical Implications.pdf.txtElectroconvulsive Therapy in Psychiatric Disorders. A Narrative Review Exploring Neuroendocrine–Immune Therapeutic Mechanisms and Clinical Implications.pdf.txtExtracted texttext/plain20https://repositorio.udes.edu.co/bitstreams/a582f4fc-4535-4b9b-b98c-ab7bd2ebc2e2/downloadb8124d19071d0062087712797db2c1a7MD53THUMBNAILElectroconvulsive Therapy in Psychiatric Disorders. A Narrative Review Exploring Neuroendocrine–Immune Therapeutic Mechanisms and Clinical Implications.pdf.jpgElectroconvulsive Therapy in Psychiatric Disorders. A Narrative Review Exploring Neuroendocrine–Immune Therapeutic Mechanisms and Clinical Implications.pdf.jpgGenerated Thumbnailimage/jpeg10841https://repositorio.udes.edu.co/bitstreams/df7de5bd-5f48-4af0-9569-dd071689f109/downloadd5b8f4cf0d5e3311ce36554e90425628MD54001/7339oai:repositorio.udes.edu.co:001/73392023-10-10 17:31:50.238https://creativecommons.org/licenses/by/4.0/© 1996-2022 The Authors, MDPI (Basel, Switzerland) unless otherwise statedhttps://repositorio.udes.edu.coRepositorio Universidad de Santandersoporte@metabiblioteca.comTGljZW5jaWEgZGUgUHVibGljYWNpw7NuIFVERVMKRGlyZWN0cmljZXMgZGUgVVNPIHkgQUNDRVNPCgo= |