Repetitive transcranial magnetic stimulation for phantom limb pain in land mine victims : A double-blinded, randomized, sham-controlled trial

8 p.

Autores:
Malavera Angarita, Mayra Alejandra
Silva Sieger, Federico Arturo
Fregni, Felipe
Carrillo Villa, Sandra
García, Ronald G.
Tipo de recurso:
Article of journal
Fecha de publicación:
2016
Institución:
Universidad de Santander
Repositorio:
Repositorio Universidad de Santander
Idioma:
eng
OAI Identifier:
oai:repositorio.udes.edu.co:001/3496
Acceso en línea:
https://repositorio.udes.edu.co/handle/001/3496
Palabra clave:
Phantom limb pain
land mine victims
rTMS
Neuropathic pain
Noninvasive brain stimulation
Rights
openAccess
License
Derechos Reservados - Universidad de Santander, 2016
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dc.title.eng.fl_str_mv Repetitive transcranial magnetic stimulation for phantom limb pain in land mine victims : A double-blinded, randomized, sham-controlled trial
title Repetitive transcranial magnetic stimulation for phantom limb pain in land mine victims : A double-blinded, randomized, sham-controlled trial
spellingShingle Repetitive transcranial magnetic stimulation for phantom limb pain in land mine victims : A double-blinded, randomized, sham-controlled trial
Phantom limb pain
land mine victims
rTMS
Neuropathic pain
Noninvasive brain stimulation
title_short Repetitive transcranial magnetic stimulation for phantom limb pain in land mine victims : A double-blinded, randomized, sham-controlled trial
title_full Repetitive transcranial magnetic stimulation for phantom limb pain in land mine victims : A double-blinded, randomized, sham-controlled trial
title_fullStr Repetitive transcranial magnetic stimulation for phantom limb pain in land mine victims : A double-blinded, randomized, sham-controlled trial
title_full_unstemmed Repetitive transcranial magnetic stimulation for phantom limb pain in land mine victims : A double-blinded, randomized, sham-controlled trial
title_sort Repetitive transcranial magnetic stimulation for phantom limb pain in land mine victims : A double-blinded, randomized, sham-controlled trial
dc.creator.fl_str_mv Malavera Angarita, Mayra Alejandra
Silva Sieger, Federico Arturo
Fregni, Felipe
Carrillo Villa, Sandra
García, Ronald G.
dc.contributor.author.spa.fl_str_mv Malavera Angarita, Mayra Alejandra
Silva Sieger, Federico Arturo
Fregni, Felipe
Carrillo Villa, Sandra
García, Ronald G.
dc.subject.proposal.eng.fl_str_mv Phantom limb pain
land mine victims
rTMS
Neuropathic pain
Noninvasive brain stimulation
topic Phantom limb pain
land mine victims
rTMS
Neuropathic pain
Noninvasive brain stimulation
description 8 p.
publishDate 2016
dc.date.issued.spa.fl_str_mv 2016-08
dc.date.accessioned.spa.fl_str_mv 2019-07-30T17:43:11Z
dc.date.available.spa.fl_str_mv 2019-07-30T17:43:11Z
dc.type.spa.fl_str_mv Artículo de revista
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dc.identifier.doi.spa.fl_str_mv 10.1016/j.jpain.2016.05.003
dc.identifier.issn.spa.fl_str_mv 1526-5900
dc.identifier.uri.spa.fl_str_mv https://repositorio.udes.edu.co/handle/001/3496
identifier_str_mv 10.1016/j.jpain.2016.05.003
1526-5900
url https://repositorio.udes.edu.co/handle/001/3496
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.ispartof.eng.fl_str_mv The Journal of Pain
dc.rights.spa.fl_str_mv Derechos Reservados - Universidad de Santander, 2016
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Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)
https://creativecommons.org/licenses/by-nc/4.0/
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spelling Malavera Angarita, Mayra Alejandraf1b3ece8-d4b2-498e-b353-86c295a068cf-1Silva Sieger, Federico Arturo9cced475-6773-4f4f-b4e7-bbebe82a3e16-1Fregni, Felipe66ff4cb7-4b17-4987-b4ba-82bb9c8953a0-1Carrillo Villa, Sandra7a85f470-8d90-41e2-8139-e279fde7fced-1García, Ronald G.41c4b822-ac96-4ffc-ac48-9d3227b75257-12019-07-30T17:43:11Z2019-07-30T17:43:11Z2016-088 p.We evaluated the effects of repetitive transcranial magnetic stimulation (rTMS) in the treatment of phantom limb pain (PLP) in land mine victims. Fifty-four patients with PLP were enrolled in a randomized, double-blinded, placebo-controlled, parallel group single-center trial. The intervention consisted of real or sham rTMS of M1 contralateral to the amputated leg. rTMS was given in series of 20 trains of 6-second duration (54-second intertrain, intensity 90% of motor threshold) at a stimulation rate of 10 Hz (1,200 pulses), 20 minutes per day, during 10 days. For the control group, a sham coil was used. The administration of active rTMS induced a significantly greater reduction in pain intensity (visual analogue scale scores) 15 days after treatment compared with sham stimulation (−53.38 ± 53.12% vs −22.93 ± 57.16%; mean between-group difference = 30.44%, 95% confidence interval, .30–60.58; P = .03). This effect was not significant 30 days after treatment. In addition, 19 subjects (70.3%) attained a clinically significant pain reduction (>30%) in the active group compared with 11 in the sham group (40.7%) 15 days after treatment (P = .03). The administration of 10 Hz rTMS on the contralateral primary motor cortex for 2 weeks in traumatic amputees with PLP induced significant clinical improvement in pain. Perspective High-frequency rTMS on the contralateral primary motor cortex of traumatic amputees induced a clinically significant pain reduction up to 15 days after treatment without any major secondary effect. These results indicate that rTMS is a safe and effective therapy in patients with PLP caused by land mine explosions.application/pdf10.1016/j.jpain.2016.05.0031526-5900https://repositorio.udes.edu.co/handle/001/3496engThe Journal of PainDerechos Reservados - Universidad de Santander, 2016info:eu-repo/semantics/openAccessAtribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)https://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2https://www.sciencedirect.com/science/article/abs/pii/S1526590016300645?via%3DihubPhantom limb painland mine victimsrTMSNeuropathic painNoninvasive brain stimulationRepetitive transcranial magnetic stimulation for phantom limb pain in land mine victims : A double-blinded, randomized, sham-controlled trialArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85PublicationBRANDED_PREVIEWRepetitive Transcranial Magnetic Stimulation for Phantom Limb Pain in Land Mine Victims. 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