Cross-tolerance between nitric oxide synthase inhibition and atypical antipsychotics modify nicotinamide-adenine-dinucleotide phosphate-diaphorase activity in mouse lateral striatum
12 p.
- Autores:
-
Prieto, Sonia G.
Silva, João C.S.
De Lima, Mairon O.
Almeida, Maria C.
Echeverry, Marcela B.
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2019
- Institución:
- Universidad de Santander
- Repositorio:
- Repositorio Universidad de Santander
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.udes.edu.co:001/3109
- Acceso en línea:
- https://repositorio.udes.edu.co/handle/001/3109
- Palabra clave:
- Clozapine
Dorsal lateral striatum
FosB
Haloperidol
Neuronal nitric oxide synthase
NG-nitro-L-arginine
Oanzapine
Rat
Ventral lateral striatum
- Rights
- openAccess
- License
- Rights - Wolters Kluwer Health, Inc., 2019
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| dc.title.eng.fl_str_mv |
Cross-tolerance between nitric oxide synthase inhibition and atypical antipsychotics modify nicotinamide-adenine-dinucleotide phosphate-diaphorase activity in mouse lateral striatum |
| title |
Cross-tolerance between nitric oxide synthase inhibition and atypical antipsychotics modify nicotinamide-adenine-dinucleotide phosphate-diaphorase activity in mouse lateral striatum |
| spellingShingle |
Cross-tolerance between nitric oxide synthase inhibition and atypical antipsychotics modify nicotinamide-adenine-dinucleotide phosphate-diaphorase activity in mouse lateral striatum Clozapine Dorsal lateral striatum FosB Haloperidol Neuronal nitric oxide synthase NG-nitro-L-arginine Oanzapine Rat Ventral lateral striatum |
| title_short |
Cross-tolerance between nitric oxide synthase inhibition and atypical antipsychotics modify nicotinamide-adenine-dinucleotide phosphate-diaphorase activity in mouse lateral striatum |
| title_full |
Cross-tolerance between nitric oxide synthase inhibition and atypical antipsychotics modify nicotinamide-adenine-dinucleotide phosphate-diaphorase activity in mouse lateral striatum |
| title_fullStr |
Cross-tolerance between nitric oxide synthase inhibition and atypical antipsychotics modify nicotinamide-adenine-dinucleotide phosphate-diaphorase activity in mouse lateral striatum |
| title_full_unstemmed |
Cross-tolerance between nitric oxide synthase inhibition and atypical antipsychotics modify nicotinamide-adenine-dinucleotide phosphate-diaphorase activity in mouse lateral striatum |
| title_sort |
Cross-tolerance between nitric oxide synthase inhibition and atypical antipsychotics modify nicotinamide-adenine-dinucleotide phosphate-diaphorase activity in mouse lateral striatum |
| dc.creator.fl_str_mv |
Prieto, Sonia G. Silva, João C.S. De Lima, Mairon O. Almeida, Maria C. Echeverry, Marcela B. |
| dc.contributor.author.spa.fl_str_mv |
Prieto, Sonia G. Silva, João C.S. De Lima, Mairon O. Almeida, Maria C. Echeverry, Marcela B. |
| dc.subject.proposal.eng.fl_str_mv |
Clozapine Dorsal lateral striatum FosB Haloperidol Neuronal nitric oxide synthase NG-nitro-L-arginine Oanzapine Rat Ventral lateral striatum |
| topic |
Clozapine Dorsal lateral striatum FosB Haloperidol Neuronal nitric oxide synthase NG-nitro-L-arginine Oanzapine Rat Ventral lateral striatum |
| description |
12 p. |
| publishDate |
2019 |
| dc.date.accessioned.spa.fl_str_mv |
2019-06-18T16:21:12Z |
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2019-06-18T16:21:12Z |
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2019-01 |
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Artículo de revista |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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10.1097/FBP.0000000000000406 |
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https://repositorio.udes.edu.co/handle/001/3109 |
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10.1097/FBP.0000000000000406 |
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| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
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Behavioural Pharmacology |
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Rights - Wolters Kluwer Health, Inc., 2019 |
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Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0) |
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https://creativecommons.org/licenses/by-nc/4.0/ |
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openAccess |
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application/pdf |
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https://journals.lww.com/behaviouralpharm/fulltext/2019/02000/Cross_tolerance_between_nitric_oxide_synthase.7.aspx |
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Universidad de Santander |
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Prieto, Sonia G.77473aca-6112-4483-91d2-b55eb60d8c0d-1Silva, João C.S.4954948a-24e0-4b68-8473-11515ca9402c-1De Lima, Mairon O.dbb964a3-ac8a-4981-bb57-08a249441184-1Almeida, Maria C.753af98c-64da-4686-a07d-b6259052a748-1Echeverry, Marcela B.86fd7611-dcd8-41e5-9635-7c1c6eb1a56e-12019-06-18T16:21:12Z2019-06-18T16:21:12Z2019-0112 p.Previous research indicates that the subchronic administration of NG-nitro-L-arginine (L-NOARG) produces tolerance to haloperidol-induced catalepsy in Swiss mice. The present study aimed to further investigate whether intermittent subchronic systemic administration of L-NOARG induces tolerance to the cataleptic effects of haloperidol as well as olanzapine or clozapine (Clz) in C57Bl mice after subchronic administration for 5 consecutive days. Striatal FosB protein expression was measured in an attempt to gain further insights into striatal mechanisms in antipsychotic-induced extrapyramidal symptoms side effects. An nicotinamide-adeninedinucleotide phosphate-diaphorase histochemical reaction was also used to investigate whether tolerance could neurons. Subchronic administration of all antipsychotics produced catalepsy, but cross-tolerance was observed only between L-NOARG (15 mg/kg, intraperitoneally) and Clz (20 mg/kg, intraperitoneally). This cross-tolerance effect was accompanied by decreased FosB protein expression in the dorsal striatum and the nucleus accumbens shell region, and reduced icotinamideadenine-dinucleotide phosphate-diaphorase activity in the dorsal and ventral lateral striatum. Overall, these results suggest that interference with the formation of nitric oxide, mainly in the dorsal and ventral lateral-striatal regions, appears to improve the cataleptic effects induced by antipsychotics acting as antagonists of low-affinity dopamine D2 receptor, such as Clz.application/pdf10.1097/FBP.0000000000000406https://repositorio.udes.edu.co/handle/001/3109engBehavioural PharmacologyRights - Wolters Kluwer Health, Inc., 2019info:eu-repo/semantics/openAccessAtribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)https://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2https://journals.lww.com/behaviouralpharm/fulltext/2019/02000/Cross_tolerance_between_nitric_oxide_synthase.7.aspxClozapineDorsal lateral striatumFosBHaloperidolNeuronal nitric oxide synthaseNG-nitro-L-arginineOanzapineRatVentral lateral striatumCross-tolerance between nitric oxide synthase inhibition and atypical antipsychotics modify nicotinamide-adenine-dinucleotide phosphate-diaphorase activity in mouse lateral striatumArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85PublicationTHUMBNAILCross-tolerance between nitric oxide synthase inhibition and atypical antipsychotics modify nicotinamide-adenine-dinucleotide phosphate-diaphorase activity in mouse lateral striatum.pdf.jpgCross-tolerance between nitric oxide synthase inhibition and atypical antipsychotics modify nicotinamide-adenine-dinucleotide phosphate-diaphorase activity in mouse lateral striatum.pdf.jpgGenerated Thumbnailimage/jpeg2047https://repositorio.udes.edu.co/bitstreams/5fb895c2-1f9b-480f-a45c-aa0df7625bd8/download10e4d1e964f51b3b7e547aec5ab978ceMD54TEXTCross-tolerance between nitric oxide synthase inhibition and atypical antipsychotics modify nicotinamide-adenine-dinucleotide phosphate-diaphorase activity in mouse lateral striatum.pdf.txtCross-tolerance between nitric oxide synthase inhibition and atypical antipsychotics modify nicotinamide-adenine-dinucleotide phosphate-diaphorase activity in mouse lateral striatum.pdf.txtExtracted texttext/plain63323https://repositorio.udes.edu.co/bitstreams/9b624949-0a5a-4f2c-acf4-b84d348dce34/download8c80d3ed8a70919abaf3aae30cecb5ebMD53LICENSElicense.txtlicense.txttext/plain; charset=utf-859https://repositorio.udes.edu.co/bitstreams/057bb4ce-d7f7-492c-b3a7-5588c79d11d7/download38d94cf55aa1bf2dac1a736ac45c881cMD52ORIGINALCross-tolerance between nitric oxide synthase inhibition and atypical antipsychotics modify nicotinamide-adenine-dinucleotide phosphate-diaphorase activity in mouse lateral striatum.pdfCross-tolerance between nitric oxide synthase inhibition and atypical antipsychotics modify nicotinamide-adenine-dinucleotide phosphate-diaphorase activity in mouse lateral striatum.pdfapplication/pdf323949https://repositorio.udes.edu.co/bitstreams/909ae268-9bfb-41a0-9b11-812e2a7899b8/download146053a695c0951f36511cf183822be7MD56001/3109oai:repositorio.udes.edu.co:001/31092023-10-10 13:25:03.663https://creativecommons.org/licenses/by-nc/4.0/Rights - Wolters Kluwer Health, Inc., 2019https://repositorio.udes.edu.coRepositorio Universidad de Santandersoporte@metabiblioteca.comTGljZW5jaWEgZGUgUHVibGljYWNpw7NuIFVERVMKRGlyZWN0cmljZXMgZGUgVVNPIHkgQUNDRVNPCgo= |