Rationale and design of a cluster randomized trial of a multifaceted intervention in people with hypertension : The Heart Outcomes Prevention and Evaluation 4 (HOPE-4) Study
10 p.
- Autores:
-
Lopez-Jaramillo, Patricio
Reid Schwalm, Jon-David
McCready, Tara
Lamelas, Pablo M.
Musa, Hadi
Yusoff, Khalid
McKee, Martin
Camacho López, Paul Anthony
López López, Jose
Majid, Fadhlina A.
Thabane, Lehana
Islam, Shofiqul
Yusuf, Salim
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2018
- Institución:
- Universidad de Santander
- Repositorio:
- Repositorio Universidad de Santander
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.udes.edu.co:001/3165
- Acceso en línea:
- https://repositorio.udes.edu.co/handle/001/3165
- Palabra clave:
- Hypertension
Heart
Outcomes
Prevention
Evaluation
- Rights
- openAccess
- License
- Derechos Reservados - Universidad de Santander, 2018
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Rationale and design of a cluster randomized trial of a multifaceted intervention in people with hypertension : The Heart Outcomes Prevention and Evaluation 4 (HOPE-4) Study |
| title |
Rationale and design of a cluster randomized trial of a multifaceted intervention in people with hypertension : The Heart Outcomes Prevention and Evaluation 4 (HOPE-4) Study |
| spellingShingle |
Rationale and design of a cluster randomized trial of a multifaceted intervention in people with hypertension : The Heart Outcomes Prevention and Evaluation 4 (HOPE-4) Study Hypertension Heart Outcomes Prevention Evaluation |
| title_short |
Rationale and design of a cluster randomized trial of a multifaceted intervention in people with hypertension : The Heart Outcomes Prevention and Evaluation 4 (HOPE-4) Study |
| title_full |
Rationale and design of a cluster randomized trial of a multifaceted intervention in people with hypertension : The Heart Outcomes Prevention and Evaluation 4 (HOPE-4) Study |
| title_fullStr |
Rationale and design of a cluster randomized trial of a multifaceted intervention in people with hypertension : The Heart Outcomes Prevention and Evaluation 4 (HOPE-4) Study |
| title_full_unstemmed |
Rationale and design of a cluster randomized trial of a multifaceted intervention in people with hypertension : The Heart Outcomes Prevention and Evaluation 4 (HOPE-4) Study |
| title_sort |
Rationale and design of a cluster randomized trial of a multifaceted intervention in people with hypertension : The Heart Outcomes Prevention and Evaluation 4 (HOPE-4) Study |
| dc.creator.fl_str_mv |
Lopez-Jaramillo, Patricio Reid Schwalm, Jon-David McCready, Tara Lamelas, Pablo M. Musa, Hadi Yusoff, Khalid McKee, Martin Camacho López, Paul Anthony López López, Jose Majid, Fadhlina A. Thabane, Lehana Islam, Shofiqul Yusuf, Salim |
| dc.contributor.author.spa.fl_str_mv |
Lopez-Jaramillo, Patricio Reid Schwalm, Jon-David McCready, Tara Lamelas, Pablo M. Musa, Hadi Yusoff, Khalid McKee, Martin Camacho López, Paul Anthony López López, Jose Majid, Fadhlina A. Thabane, Lehana Islam, Shofiqul Yusuf, Salim |
| dc.subject.proposal.eng.fl_str_mv |
Hypertension Heart Outcomes Prevention Evaluation |
| topic |
Hypertension Heart Outcomes Prevention Evaluation |
| description |
10 p. |
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2018 |
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2018-09 |
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2019-06-19T22:42:08Z |
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2019-06-19T22:42:08Z |
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10.1016/j.ahj.2018.06.004 1097-6744 0002-8703 |
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https://repositorio.udes.edu.co/handle/001/3165 |
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10.1016/j.ahj.2018.06.004 1097-6744 0002-8703 |
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eng |
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eng |
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American Heart Journal |
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Derechos Reservados - Universidad de Santander, 2018 |
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Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0) |
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https://creativecommons.org/licenses/by-nc/4.0/ |
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Lopez-Jaramillo, Patricio9a71267b-dcb0-4d31-b37d-2d30be58d4d2-1Reid Schwalm, Jon-David5ee029bb-0fcc-4ad5-99f2-16e807c04dc3-1McCready, Tara2e01aadd-bde9-4281-96ec-00e0c64a8a5d-1Lamelas, Pablo M.1225bf77-98c8-4037-8320-6df2320ce51f-1Musa, Hadic87bd7e0-ec2c-49e4-8c89-0e29c2a79ec2-1Yusoff, Khalid933db13d-f5bb-4ea6-91a5-68eea1ca9ffc-1McKee, Martin5258b372-6b7d-4e6f-aaa6-0e81538245af-1Camacho López, Paul Anthony594e3832-d941-4df3-b3cc-a2c088dca74c-1López López, Josedec089a0-85cc-492d-8073-340b085c5e5d-1Majid, Fadhlina A.d5f852f3-3cb7-4ffd-81d5-831b5f5bda3a-1Thabane, Lehana42609cea-4e33-41d3-9586-fe88631d8473-1Islam, Shofiqule02df6ce-a317-49c4-8ebd-72d82c266011-1Yusuf, Salim06a836b5-f5e3-41d9-a516-9cc46e5d7948-12019-06-19T22:42:08Z2019-06-19T22:42:08Z2018-0910 p.Background: Cardiovascular disease is the leading cause of death throughout the world, with the majority of deaths occurring in low- and middle-income countries. Despite clear evidence for the benefits of blood pressure reduction and availability of safe and low-cost medications, most individuals are either unaware of their condition or not adequately treated. Objective: The primary objective of this study is to evaluatewhether a community-based, multifaceted intervention package primarily provided by nonphysician health workers can improve long-term cardiovascular risk in people with hypertension by addressing identified barriers at the patient, health care provider, and health system levels. Methods/design: HOPE-4 is a community-based, parallel-group, cluster randomized controlled trial involving 30 communities (1,376 participants) in Colombia and Malaysia. Participants ≥50 years old and with newly diagnosed or poorly controlled hypertension were included. Communities were randomized to usual care or to amultifaceted intervention package that entails (1) detection, treatment, and control of cardiovascular risk factors by nonphysician health workers in the community, who use tablet-based simplified management algorithms, decision support, and counseling programs; (2) free dispensation of combination antihypertensive and cholesterol-loweringmedications, supervised by local physicians; and (3) support from a participant-nominated treatment supporter (either a friend or family member). The primary outcome is the change in Framingham Risk Score after 12 months between the intervention and control communities. Secondary outcomes including change in blood pressure, lipid levels, and Interheart Risk Score will be evaluated. Significance: If successful, the study could serve as a model to develop low-cost, effective, and scalable strategies to reduce cardiovascular risk in people with hypertension.application/pdf10.1016/j.ahj.2018.06.0041097-67440002-8703https://repositorio.udes.edu.co/handle/001/3165engAmerican Heart JournalDerechos Reservados - Universidad de Santander, 2018info:eu-repo/semantics/openAccessAtribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)https://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2https://www.sciencedirect.com/science/article/pii/S0002870318301807?via%3DihubHypertensionHeartOutcomesPreventionEvaluationRationale and design of a cluster randomized trial of a multifaceted intervention in people with hypertension : The Heart Outcomes Prevention and Evaluation 4 (HOPE-4) StudyArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85PublicationTHUMBNAILRationale and design of a cluster randomized trial of a multifaceted intervention in people with hypertension. 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