Effect of Lippia alba and Cymbopogon citratus essential oils on biofilms of Streptococcus mutans and cytotoxicity in CHO cells
6 p.
- Autores:
-
Tofiño Rivera, Adriana Patricia
Ortega Cuadros, Mailen
Galvis Pareja, D.
Jiménez Rios, Hedilka
Merini, Luciano J.
Martínez Pabón, M.C.
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2016
- Institución:
- Universidad de Santander
- Repositorio:
- Repositorio Universidad de Santander
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.udes.edu.co:001/3222
- Acceso en línea:
- https://repositorio.udes.edu.co/handle/001/3222
- Palabra clave:
- Dental caries
Biofilms
Streptococcus mutans
Cytotoxicity
Essential oils
- Rights
- openAccess
- License
- Derechos Reservados - Universidad de Santander, 2016
| id |
RUDES2_5053825a0f51a14799708b46a74e23e7 |
|---|---|
| oai_identifier_str |
oai:repositorio.udes.edu.co:001/3222 |
| network_acronym_str |
RUDES2 |
| network_name_str |
Repositorio Universidad de Santander |
| repository_id_str |
|
| dc.title.eng.fl_str_mv |
Effect of Lippia alba and Cymbopogon citratus essential oils on biofilms of Streptococcus mutans and cytotoxicity in CHO cells |
| title |
Effect of Lippia alba and Cymbopogon citratus essential oils on biofilms of Streptococcus mutans and cytotoxicity in CHO cells |
| spellingShingle |
Effect of Lippia alba and Cymbopogon citratus essential oils on biofilms of Streptococcus mutans and cytotoxicity in CHO cells Dental caries Biofilms Streptococcus mutans Cytotoxicity Essential oils |
| title_short |
Effect of Lippia alba and Cymbopogon citratus essential oils on biofilms of Streptococcus mutans and cytotoxicity in CHO cells |
| title_full |
Effect of Lippia alba and Cymbopogon citratus essential oils on biofilms of Streptococcus mutans and cytotoxicity in CHO cells |
| title_fullStr |
Effect of Lippia alba and Cymbopogon citratus essential oils on biofilms of Streptococcus mutans and cytotoxicity in CHO cells |
| title_full_unstemmed |
Effect of Lippia alba and Cymbopogon citratus essential oils on biofilms of Streptococcus mutans and cytotoxicity in CHO cells |
| title_sort |
Effect of Lippia alba and Cymbopogon citratus essential oils on biofilms of Streptococcus mutans and cytotoxicity in CHO cells |
| dc.creator.fl_str_mv |
Tofiño Rivera, Adriana Patricia Ortega Cuadros, Mailen Galvis Pareja, D. Jiménez Rios, Hedilka Merini, Luciano J. Martínez Pabón, M.C. |
| dc.contributor.author.spa.fl_str_mv |
Tofiño Rivera, Adriana Patricia Ortega Cuadros, Mailen Galvis Pareja, D. Jiménez Rios, Hedilka Merini, Luciano J. Martínez Pabón, M.C. |
| dc.subject.proposal.eng.fl_str_mv |
Dental caries Biofilms Streptococcus mutans Cytotoxicity Essential oils |
| topic |
Dental caries Biofilms Streptococcus mutans Cytotoxicity Essential oils |
| description |
6 p. |
| publishDate |
2016 |
| dc.date.issued.spa.fl_str_mv |
2016-10-17 |
| dc.date.accessioned.spa.fl_str_mv |
2019-06-28T13:53:25Z |
| dc.date.available.spa.fl_str_mv |
2019-06-28T13:53:25Z |
| dc.type.spa.fl_str_mv |
Artículo de revista |
| dc.type.coar.fl_str_mv |
http://purl.org/coar/resource_type/c_2df8fbb1 |
| dc.type.coarversion.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| dc.type.coar.spa.fl_str_mv |
http://purl.org/coar/resource_type/c_6501 |
| dc.type.content.spa.fl_str_mv |
Text |
| dc.type.driver.spa.fl_str_mv |
info:eu-repo/semantics/article |
| dc.type.redcol.spa.fl_str_mv |
http://purl.org/redcol/resource_type/ART |
| dc.type.version.spa.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
| format |
http://purl.org/coar/resource_type/c_6501 |
| status_str |
publishedVersion |
| dc.identifier.doi.spa.fl_str_mv |
10.1016/j.jep.2016.10.044 |
| dc.identifier.issn.spa.fl_str_mv |
0378-8741 |
| dc.identifier.uri.spa.fl_str_mv |
https://repositorio.udes.edu.co/handle/001/3222 |
| identifier_str_mv |
10.1016/j.jep.2016.10.044 0378-8741 |
| url |
https://repositorio.udes.edu.co/handle/001/3222 |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
| dc.relation.ispartof.eng.fl_str_mv |
Journal of Ethnopharmacology |
| dc.rights.spa.fl_str_mv |
Derechos Reservados - Universidad de Santander, 2016 |
| dc.rights.coar.fl_str_mv |
http://purl.org/coar/access_right/c_abf2 |
| dc.rights.accessrights.spa.fl_str_mv |
info:eu-repo/semantics/openAccess |
| dc.rights.creativecommons.spa.fl_str_mv |
Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0) |
| dc.rights.uri.spa.fl_str_mv |
https://creativecommons.org/licenses/by-nc/4.0/ |
| rights_invalid_str_mv |
Derechos Reservados - Universidad de Santander, 2016 Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0) https://creativecommons.org/licenses/by-nc/4.0/ http://purl.org/coar/access_right/c_abf2 |
| eu_rights_str_mv |
openAccess |
| dc.format.mimetype.spa.fl_str_mv |
application/pdf |
| dc.source.eng.fl_str_mv |
https://www.sciencedirect.com/science/article/pii/S0378874116313289 |
| institution |
Universidad de Santander |
| bitstream.url.fl_str_mv |
https://repositorio.udes.edu.co/bitstreams/e34c1d06-2eee-42f2-8482-d63b0f841cd0/download https://repositorio.udes.edu.co/bitstreams/6dc3cd56-be4d-4b32-916b-42954b785877/download https://repositorio.udes.edu.co/bitstreams/6c57c37a-3fcc-4612-b60c-0d6ecfddd94c/download https://repositorio.udes.edu.co/bitstreams/f1930ea8-92ce-4fef-ad8f-6c404f98eef2/download |
| bitstream.checksum.fl_str_mv |
5ef84375bd3f6ba9a03baf6b269853d6 38d94cf55aa1bf2dac1a736ac45c881c 80103791589326740bddb17d7b0a7209 cb8c8594ff2a7e2ba1974fda12a8d159 |
| bitstream.checksumAlgorithm.fl_str_mv |
MD5 MD5 MD5 MD5 |
| repository.name.fl_str_mv |
Repositorio Universidad de Santander |
| repository.mail.fl_str_mv |
soporte@metabiblioteca.com |
| _version_ |
1814158961302044672 |
| spelling |
Tofiño Rivera, Adriana Patricia7f04ceff-f997-4720-bed7-c14a437f75c9-1Ortega Cuadros, Mailena7466ea1-b2a9-4122-839c-90bac1ae2e65-1Galvis Pareja, D.5b32ee50-91b4-476c-a479-2e6f63f4c75d-1Jiménez Rios, Hedilka31241f68-2112-4ec6-afd6-d30e1ad12baf-1Merini, Luciano J.4bf1ea77-743a-46fd-9c04-9a8de294fd28-1Martínez Pabón, M.C.37b83c28-c50c-45bb-9b9e-be20712cf443-12019-06-28T13:53:25Z2019-06-28T13:53:25Z2016-10-176 p.Background Caries is a public health problem, given that it prevails in 60 to 90% of the school-age global population. Multiple factors interact in its etiology, among them dental plaque is necessary to have lactic acid producing microorganisms like Streptococcus from he Mutans group. Existing prevention and treatment measures are not totally effective and generate adverse effects, which is why it is necessary to search for complementary strategies for their management. Aim The study sought to evaluate the eradication capacity of Streptococcus mutans biofilms and the toxicity on eukaryotic cells of Lippia alba and Cymbopogon citratus essential oils. Methodology Essential oils were extracted from plant material through steam distillation and then its chemical composition was determined. The MBEC-high-throughput (MBEC-HTP) (Innovotech, Edmonton, Alberta, Canada) assay used to determine the eradication concentration of S. mutans ATCC 35668 strain biofilms. Cytotoxicity was evaluated on CHO cells through the MTT cell proliferation assay. Results The major components in both oils were Geraniol and Citral; in L. alba 18.9% and 15.9%, respectively, and in C. citratus 31.3% and 26.7%. The L. alba essential oils presented eradication activity against S. mutans biofilms of 95.8% in 0.01 mg/dL concentration and C. citratus essential oils showed said eradication activity of 95.4% at 0.1, 0.01 mg/dL concentrations and of 93.1% in the 0.001 mg/dL concentration; none of the concentrations of both essential oils showed toxicity on CHO cells during 24 h. Conclusion The L. alba and C. citratus essential oils showed eradication activity against S. mutans biofilms and null cytotoxicity, evidencing the need to conduct further studies that can identify their active components and in order to guide a safe use in treating and preventing dental caries. Chemical compounds studied in this article List of up to 10 names of chemical compounds studied in the article. Geranial. Neral. Myrcene. Geraniol. (E)-Caryophyllene. trans-Verbenol. Geranyl acetate. cis-Verbenol. Germacrene D. 37-Dimethyl-26-octadiene-1-olapplication/pdf10.1016/j.jep.2016.10.0440378-8741https://repositorio.udes.edu.co/handle/001/3222engJournal of EthnopharmacologyDerechos Reservados - Universidad de Santander, 2016info:eu-repo/semantics/openAccessAtribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)https://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2https://www.sciencedirect.com/science/article/pii/S0378874116313289Dental cariesBiofilmsStreptococcus mutansCytotoxicityEssential oilsEffect of Lippia alba and Cymbopogon citratus essential oils on biofilms of Streptococcus mutans and cytotoxicity in CHO cellsArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85PublicationTHUMBNAILEffect of Lippia alba and Cymbopogon citratus essential oils on biofilms of Streptococcus mutans and cytotoxicity in CHO cells.pdf.jpgEffect of Lippia alba and Cymbopogon citratus essential oils on biofilms of Streptococcus mutans and cytotoxicity in CHO cells.pdf.jpgGenerated Thumbnailimage/jpeg1690https://repositorio.udes.edu.co/bitstreams/e34c1d06-2eee-42f2-8482-d63b0f841cd0/download5ef84375bd3f6ba9a03baf6b269853d6MD54LICENSElicense.txtlicense.txttext/plain; charset=utf-859https://repositorio.udes.edu.co/bitstreams/6dc3cd56-be4d-4b32-916b-42954b785877/download38d94cf55aa1bf2dac1a736ac45c881cMD52ORIGINALEffect of Lippia alba and Cymbopogon citratus essential oils on biofilms of Streptococcus mutans and cytotoxicity in CHO cells.pdfEffect of Lippia alba and Cymbopogon citratus essential oils on biofilms of Streptococcus mutans and cytotoxicity in CHO cells.pdfapplication/pdf333559https://repositorio.udes.edu.co/bitstreams/6c57c37a-3fcc-4612-b60c-0d6ecfddd94c/download80103791589326740bddb17d7b0a7209MD55TEXTEffect of Lippia alba and Cymbopogon citratus essential oils on biofilms of Streptococcus mutans and cytotoxicity in CHO cells.pdf.txtEffect of Lippia alba and Cymbopogon citratus essential oils on biofilms of Streptococcus mutans and cytotoxicity in CHO cells.pdf.txtExtracted texttext/plain33135https://repositorio.udes.edu.co/bitstreams/f1930ea8-92ce-4fef-ad8f-6c404f98eef2/downloadcb8c8594ff2a7e2ba1974fda12a8d159MD53001/3222oai:repositorio.udes.edu.co:001/32222023-10-10 17:15:53.536https://creativecommons.org/licenses/by-nc/4.0/Derechos Reservados - Universidad de Santander, 2016https://repositorio.udes.edu.coRepositorio Universidad de Santandersoporte@metabiblioteca.comTGljZW5jaWEgZGUgUHVibGljYWNpw7NuIFVERVMKRGlyZWN0cmljZXMgZGUgVVNPIHkgQUNDRVNPCgo= |