Simulation of inference test performance for minimum inhibitory concentration censored data

Digital

Autores:
Torres-Mantilla, Hugo A.
Cuesta-Herrera, L.
Andrades-Grassi, J.E.
Bianchi, G.
Tipo de recurso:
Documento de conferencia en no proceso
Fecha de publicación:
2022
Institución:
Universidad de Santander
Repositorio:
Repositorio Universidad de Santander
Idioma:
eng
OAI Identifier:
oai:repositorio.udes.edu.co:001/7355
Acceso en línea:
https://doi.org/10.1088/1742-6596/2153/1/012013
https://repositorio.udes.edu.co/handle/001/7355
Palabra clave:
Rights
openAccess
License
© Copyright 2022 The Authors, IOP Publishing
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spelling Torres-Mantilla, Hugo A.bf6ea94d-20ce-46c4-93c4-7b44aa632167-1Cuesta-Herrera, L.6e9f37e3-23b1-4bdf-82a0-2ae06cc165a0-1Andrades-Grassi, J.E.d17e33ae-4ba6-4c3d-9038-c8cfe34abf7d-1Bianchi, G.c6775cf3-5f93-45b0-a37a-130826bf243e-12022-08-08T15:01:48Z2022-08-08T15:01:48Z2022-02-05DigitalThe estimation of the minimum inhibitory concentration is usually performed by a method of serial dilutions by a factor of 2, introducing the overestimation of antimicrobial efficacy, quantified by a simulation model that shows that the variability of the bias is higher for the standard deviation, being dependent on the metric distance to the values of the concentrations used. We use a methodological approach through modeling and simulation for the measurement error of physical variables with censored information, proposing a new inference method based on the calculation of the exact probability for the set of possible samples from nmeasurements that allows quantifying the p-value in one or two independent sample tests for the comparison of censored data means. Tests based on exact probability methods offer a reasonable solution for small sample sizes, with statistical power varying according to the hypothesis evaluated, providing insight into the limitations of censored data analysis and providing a tool for decision making in the diagnosis of antimicrobial efficacy.7 papplication/pdfhttps://doi.org/10.1088/1742-6596/2153/1/012013https://repositorio.udes.edu.co/handle/001/7355engReino UnidoH A Torres-Mantilla et al 2022 J. Phys.: Conf. Ser. 2153 01201313-15 October 2021San José de Cúcuta, ColombiaFirst International Seminar on Physical Infrastructure (1st ISPI)© Copyright 2022 The Authors, IOP Publishinginfo:eu-repo/semantics/openAccessAtribución 4.0 Internacional (CC BY 4.0)https://creativecommons.org/licenses/by/4.0/http://purl.org/coar/access_right/c_abf2https://iopscience.iop.org/article/10.1088/1742-6596/2153/1/012013/pdfSimulation of inference test performance for minimum inhibitory concentration censored dataDocumento de Conferenciahttp://purl.org/coar/resource_type/c_18cphttp://purl.org/coar/resource_type/c_c94fTextinfo:eu-repo/semantics/conferenceObjecthttp://purl.org/redcol/resource_type/ARTOTRinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85Todas las AudienciasPublicationORIGINALSimulation of inference test performance for minimum inhibitory concentration censored data.pdfSimulation of inference test performance for minimum inhibitory concentration censored data.pdfapplication/pdf222818https://repositorio.udes.edu.co/bitstreams/ed459a8d-a794-4916-9ac1-1048fcf8b6c5/download879661629bff48fce220c2e5f3a8ca3dMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-859https://repositorio.udes.edu.co/bitstreams/6a740255-f073-48a8-b6a1-c45777bcfb36/download38d94cf55aa1bf2dac1a736ac45c881cMD52TEXTSimulation of inference test performance for minimum inhibitory concentration censored data.pdf.txtSimulation of inference test performance for minimum inhibitory concentration censored data.pdf.txtExtracted texttext/plain5https://repositorio.udes.edu.co/bitstreams/597f8929-666b-43ea-93ed-9b85a8427be1/download5dbe86c1111d64f45ba435df98fdc825MD53THUMBNAILSimulation of inference test performance for minimum inhibitory concentration censored data.pdf.jpgSimulation of inference test performance for minimum inhibitory concentration censored data.pdf.jpgGenerated Thumbnailimage/jpeg11752https://repositorio.udes.edu.co/bitstreams/dba9d2d3-0c1e-4a20-8c5d-91f02a7b313a/download1930f9aa34bdc3be1712336f38e77198MD54001/7355oai:repositorio.udes.edu.co:001/73552023-10-12 16:19:24.839https://creativecommons.org/licenses/by/4.0/© Copyright 2022 The Authors, IOP Publishinghttps://repositorio.udes.edu.coRepositorio Universidad de Santandersoporte@metabiblioteca.comTGljZW5jaWEgZGUgUHVibGljYWNpw7NuIFVERVMKRGlyZWN0cmljZXMgZGUgVVNPIHkgQUNDRVNPCgo=
dc.title.spa.fl_str_mv Simulation of inference test performance for minimum inhibitory concentration censored data
title Simulation of inference test performance for minimum inhibitory concentration censored data
spellingShingle Simulation of inference test performance for minimum inhibitory concentration censored data
title_short Simulation of inference test performance for minimum inhibitory concentration censored data
title_full Simulation of inference test performance for minimum inhibitory concentration censored data
title_fullStr Simulation of inference test performance for minimum inhibitory concentration censored data
title_full_unstemmed Simulation of inference test performance for minimum inhibitory concentration censored data
title_sort Simulation of inference test performance for minimum inhibitory concentration censored data
dc.creator.fl_str_mv Torres-Mantilla, Hugo A.
Cuesta-Herrera, L.
Andrades-Grassi, J.E.
Bianchi, G.
dc.contributor.author.none.fl_str_mv Torres-Mantilla, Hugo A.
Cuesta-Herrera, L.
Andrades-Grassi, J.E.
Bianchi, G.
description Digital
publishDate 2022
dc.date.accessioned.none.fl_str_mv 2022-08-08T15:01:48Z
dc.date.available.none.fl_str_mv 2022-08-08T15:01:48Z
dc.date.issued.none.fl_str_mv 2022-02-05
dc.type.spa.fl_str_mv Documento de Conferencia
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https://repositorio.udes.edu.co/handle/001/7355
dc.language.iso.spa.fl_str_mv eng
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dc.relation.cites.none.fl_str_mv H A Torres-Mantilla et al 2022 J. Phys.: Conf. Ser. 2153 012013
dc.relation.conferencedate.spa.fl_str_mv 13-15 October 2021
dc.relation.conferenceplace.spa.fl_str_mv San José de Cúcuta, Colombia
dc.relation.ispartofconference.spa.fl_str_mv First International Seminar on Physical Infrastructure (1st ISPI)
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Atribución 4.0 Internacional (CC BY 4.0)
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