Neuroradiology and histopathology in two cases of adult medulloblastoma
6 p.
- Autores:
-
Romero Rojas, Alfredo E.
Diaz Perez, Julio A.
Raju, Sharat
Lozano Castillo, Alfonso
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2014
- Institución:
- Universidad de Santander
- Repositorio:
- Repositorio Universidad de Santander
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.udes.edu.co:001/3564
- Acceso en línea:
- https://repositorio.udes.edu.co/handle/001/3564
- Palabra clave:
- Medulloblastoma
Adult patients
Neuroradiology
Histopathology
Immunohistochemistry
Molecular imaging
- Rights
- openAccess
- License
- Derechos Reservados - Universidad de Santander, 2014
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Romero Rojas, Alfredo E.3e465c15-1707-4dfe-ae44-dc7225c73f4e-1Diaz Perez, Julio A.c3667314-adc6-4295-bb6b-f33572645af0-1Raju, Sharat6b0ba04e-feef-4e92-9e8e-8431582ccf27-1Lozano Castillo, Alfonso4a1c9a4a-9717-40df-9848-18c3b5e8574e-12019-08-09T17:02:09Z2019-08-09T17:02:09Z20146 p.Medulloblastoma (MB) is the most common central nervous system neoplasm in children and only rarely presents in the adult population. Recent molecular biology findings have characterized MB as a heterogeneous neoplasm distinguished by well-defined tumour subsets each with specific histologic and molecular features. Available immunohistochemical stains can now be used to differentiate the distinct molecular types of MB. This report analyzed the histopathologic and neuroradiologic features of two new cases of adult MB. Imaging studies in these patients revealed the morphological appearance of high-grade, well-circumscribed heterogeneous tumours with necrosis, located laterally within the posterior cranial fossa. Histopathology of resected samples demonstrated high-grade tumours (WHO grade IV) containing sheets of undifferentiated neural cells with high mitotic activity and evidence of necrosis. The histopathologic and molecular characteristics of these cases of MB are reviewed for potential applications in new molecular methods of imaging.application/pdf10.15274/NRJ-2014-100212385-19961971-4009https://repositorio.udes.edu.co/handle/001/3564engNeuroradiology JournalDerechos Reservados - Universidad de Santander, 2014info:eu-repo/semantics/openAccessAtribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)https://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202854/pdf/NRJ-27-163.pdfMedulloblastomaAdult patientsNeuroradiologyHistopathologyImmunohistochemistryMolecular imagingNeuroradiology and histopathology in two cases of adult medulloblastomaArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85PublicationTHUMBNAILNeuroradiology and histopathology in two cases of adult medulloblastoma.pdf.jpgNeuroradiology and histopathology in two cases of adult medulloblastoma.pdf.jpgGenerated Thumbnailimage/jpeg1580https://repositorio.udes.edu.co/bitstreams/28233dae-b8c2-40ee-8a6b-2000193b6f05/downloada1b2064c8bc4fa70d09c9744aa9e5358MD54TEXTNeuroradiology and histopathology in two cases of adult medulloblastoma.pdf.txtNeuroradiology and histopathology in two cases of adult medulloblastoma.pdf.txtExtracted texttext/plain19952https://repositorio.udes.edu.co/bitstreams/db1292f4-b890-4fe2-b962-6ca453fd78ed/download76f04e13c288826aa0ccdd5aded2fd45MD53LICENSElicense.txtlicense.txttext/plain; charset=utf-859https://repositorio.udes.edu.co/bitstreams/4f913973-6abc-4916-b69f-262f83bf0783/download38d94cf55aa1bf2dac1a736ac45c881cMD52ORIGINALNeuroradiology and histopathology in two cases of adult medulloblastoma.pdfNeuroradiology and histopathology in two cases of adult medulloblastoma.pdfapplication/pdf315312https://repositorio.udes.edu.co/bitstreams/0482bbd8-438d-42b9-9995-aaafe2770fd4/download6696b96f88d21272c6b5f6241fbda756MD55001/3564oai:repositorio.udes.edu.co:001/35642023-10-10 13:12:33.807https://creativecommons.org/licenses/by-nc/4.0/Derechos Reservados - Universidad de Santander, 2014https://repositorio.udes.edu.coRepositorio Universidad de Santandersoporte@metabiblioteca.comTGljZW5jaWEgZGUgUHVibGljYWNpw7NuIFVERVMKRGlyZWN0cmljZXMgZGUgVVNPIHkgQUNDRVNPCgo= |
| dc.title.eng.fl_str_mv |
Neuroradiology and histopathology in two cases of adult medulloblastoma |
| title |
Neuroradiology and histopathology in two cases of adult medulloblastoma |
| spellingShingle |
Neuroradiology and histopathology in two cases of adult medulloblastoma Medulloblastoma Adult patients Neuroradiology Histopathology Immunohistochemistry Molecular imaging |
| title_short |
Neuroradiology and histopathology in two cases of adult medulloblastoma |
| title_full |
Neuroradiology and histopathology in two cases of adult medulloblastoma |
| title_fullStr |
Neuroradiology and histopathology in two cases of adult medulloblastoma |
| title_full_unstemmed |
Neuroradiology and histopathology in two cases of adult medulloblastoma |
| title_sort |
Neuroradiology and histopathology in two cases of adult medulloblastoma |
| dc.creator.fl_str_mv |
Romero Rojas, Alfredo E. Diaz Perez, Julio A. Raju, Sharat Lozano Castillo, Alfonso |
| dc.contributor.author.spa.fl_str_mv |
Romero Rojas, Alfredo E. Diaz Perez, Julio A. Raju, Sharat Lozano Castillo, Alfonso |
| dc.subject.proposal.eng.fl_str_mv |
Medulloblastoma Adult patients Neuroradiology Histopathology Immunohistochemistry Molecular imaging |
| topic |
Medulloblastoma Adult patients Neuroradiology Histopathology Immunohistochemistry Molecular imaging |
| description |
6 p. |
| publishDate |
2014 |
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2014 |
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2019-08-09T17:02:09Z |
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2019-08-09T17:02:09Z |
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Artículo de revista |
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http://purl.org/coar/resource_type/c_2df8fbb1 |
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10.15274/NRJ-2014-10021 |
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2385-1996 1971-4009 |
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https://repositorio.udes.edu.co/handle/001/3564 |
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eng |
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eng |
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Neuroradiology Journal |
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Derechos Reservados - Universidad de Santander, 2014 |
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info:eu-repo/semantics/openAccess |
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Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0) |
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https://creativecommons.org/licenses/by-nc/4.0/ |
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Derechos Reservados - Universidad de Santander, 2014 Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0) https://creativecommons.org/licenses/by-nc/4.0/ http://purl.org/coar/access_right/c_abf2 |
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openAccess |
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application/pdf |
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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202854/pdf/NRJ-27-163.pdf |
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