Enkephalins and ACTH in the mammalian nervous system
Digital
- Autores:
-
Duque-Diaz, Ewing Rafael
Alvarez-Ojeda, Olga
Coveñas, Rafael
- Tipo de recurso:
- Part of book
- Fecha de publicación:
- 2019
- Institución:
- Universidad de Santander
- Repositorio:
- Repositorio Universidad de Santander
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.udes.edu.co:001/6749
- Acceso en línea:
- https://doi.org/10.1016/bs.vh.2019.05.001
https://repositorio.udes.edu.co/handle/001/6749
- Palabra clave:
- Adrenocorticotropin hormone
Leucine-enkephalin
Methionine-enkephalin
Opioid
Pro-enkephalin
- Rights
- closedAccess
- License
- Copyright © 2019 Elsevier Inc. All rights reserved.
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Enkephalins and ACTH in the mammalian nervous system |
| title |
Enkephalins and ACTH in the mammalian nervous system |
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Enkephalins and ACTH in the mammalian nervous system Adrenocorticotropin hormone Leucine-enkephalin Methionine-enkephalin Opioid Pro-enkephalin |
| title_short |
Enkephalins and ACTH in the mammalian nervous system |
| title_full |
Enkephalins and ACTH in the mammalian nervous system |
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Enkephalins and ACTH in the mammalian nervous system |
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Enkephalins and ACTH in the mammalian nervous system |
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Enkephalins and ACTH in the mammalian nervous system |
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Duque-Diaz, Ewing Rafael Alvarez-Ojeda, Olga Coveñas, Rafael |
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Duque-Diaz, Ewing Rafael Alvarez-Ojeda, Olga Coveñas, Rafael |
| dc.subject.proposal.eng.fl_str_mv |
Adrenocorticotropin hormone Leucine-enkephalin Methionine-enkephalin Opioid Pro-enkephalin |
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Adrenocorticotropin hormone Leucine-enkephalin Methionine-enkephalin Opioid Pro-enkephalin |
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Digital |
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2019 |
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10: 0128188588 |
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9780128188583 |
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193 |
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Ewing Duque-Díaz, Olga Alvarez-Ojeda, Rafael Coveñas, Chapter Seven - Enkephalins and ACTH in the mammalian nervous system, Editor(s): Gerald Litwack, Vitamins and Hormones, Academic Press, Volume 111, 2019, Pages 147-193, ISSN 0083-6729, ISBN 9780128188583, https://doi.org/10.1016/bs.vh.2019.05.001. |
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Vitamins and Hormones |
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Copyright © 2019 Elsevier Inc. All rights reserved. |
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47 p |
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Duque-Diaz, Ewing Rafael53eb6a81-b5ad-43d8-964f-ca7c60e2c128-1Alvarez-Ojeda, Olgad9fb3e96-e240-4eaf-9b5d-24d2b6bb11f5-1Coveñas, Rafael99a3e7ad-fa30-43b1-893a-9c3d6164eed3-12022-05-09T23:11:07Z2022-05-09T23:11:07Z2019-08-13DigitalThe pentapeptides methionine-enkephalin and leucine-enkephalin belong to the opioid family of peptides, and the non-opiate peptide adrenocorticotropin hormone (ACTH) to the melanocortin peptide family. Enkephalins/ACTH are derived from pro-enkephalin, pro-dynorphin or pro-opiomelanocortin precursors and, via opioid and melanocortin receptors, are responsible for many biological activities. Enkephalins exhibit the highest affinity for the δ receptor, followed by the μ and κ receptors, whereas ACTH binds to the five subtypes of melanocortin receptor, and is the only member of the melanocortin family of peptides that binds to the melanocortin-receptor 2 (ACTH receptor). Enkephalins/ACTH and their receptors exhibit a widespread anatomical distribution. Enkephalins are involved in analgesia, angiogenesis, blood pressure, embryonic development, emotional behavior, feeding, hypoxia, limbic system modulation, neuroprotection, peristalsis, and wound repair; as well as in hepatoprotective, motor, neuroendocrine and respiratory mechanisms. ACTH plays a role in acetylcholine release, aggressive behavior, blood pressure, bone maintenance, hyperalgesia, feeding, fever, grooming, learning, lipolysis, memory, nerve injury repair, neuroprotection, sexual behavior, sleep, social behavior, tissue growth and stimulates the synthesis and secretion of glucocorticoids. Enkephalins/ACTH are also involved in many pathologies. Enkephalins are implicated in alcoholism, cancer, colitis, depression, heart failure, Huntington's disease, influenza A virus infection, ischemia, multiple sclerosis, and stress. ACTH plays a role in Addison's disease, alcoholism, cancer, Cushing's disease, dermatitis, encephalitis, epilepsy, Graves' disease, Guillain-Barré syndrome, multiple sclerosis, podocytopathies, and stress. In this review, we provide an updated description of the enkephalinergic and ACTH systems.47 papplication/pdfhttps://doi.org/10.1016/bs.vh.2019.05.00110: 01281885889780128188583https://repositorio.udes.edu.co/handle/001/6749engUSA193147Ewing Duque-Díaz, Olga Alvarez-Ojeda, Rafael Coveñas, Chapter Seven - Enkephalins and ACTH in the mammalian nervous system, Editor(s): Gerald Litwack, Vitamins and Hormones, Academic Press, Volume 111, 2019, Pages 147-193, ISSN 0083-6729, ISBN 9780128188583, https://doi.org/10.1016/bs.vh.2019.05.001.Vitamins and HormonesCopyright © 2019 Elsevier Inc. All rights reserved.info:eu-repo/semantics/closedAccessAtribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)https://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_14cbhttps://www.sciencedirect.com/science/article/abs/pii/S0083672919300378Adrenocorticotropin hormoneLeucine-enkephalinMethionine-enkephalinOpioidPro-enkephalinEnkephalins and ACTH in the mammalian nervous systemCapítulo - Parte de Librohttp://purl.org/coar/resource_type/c_3248Textinfo:eu-repo/semantics/bookParthttps://purl.org/redcol/resource_type/CAP_LIBinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85Todas las AudienciasPublicationORIGINALEnkephalins and ACTH in the mammalian nervous system.pdfEnkephalins and ACTH in the mammalian nervous system.pdfapplication/pdf216986https://repositorio.udes.edu.co/bitstreams/109b8fa5-6352-444c-b623-18a8323fedf4/download278fc312130c2213c29f08e40bff0ea6MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-859https://repositorio.udes.edu.co/bitstreams/9d3fc6b2-b464-4512-99a3-08f0b8d711c6/download38d94cf55aa1bf2dac1a736ac45c881cMD52TEXTEnkephalins and ACTH in the mammalian nervous system.pdf.txtEnkephalins and ACTH in the mammalian nervous system.pdf.txtExtracted texttext/plain5https://repositorio.udes.edu.co/bitstreams/40fa5775-3c07-48cf-ba02-f44917de3a12/download5dbe86c1111d64f45ba435df98fdc825MD53THUMBNAILEnkephalins and ACTH in the mammalian nervous system.pdf.jpgEnkephalins and ACTH in the mammalian nervous system.pdf.jpgGenerated Thumbnailimage/jpeg10113https://repositorio.udes.edu.co/bitstreams/a98426cb-6ba2-4953-a998-28f627915674/downloaddca699f2730e2660c390a40182ee9c9eMD54001/6749oai:repositorio.udes.edu.co:001/67492023-10-10 12:57:01.664https://creativecommons.org/licenses/by-nc/4.0/Copyright © 2019 Elsevier Inc. All rights reserved.https://repositorio.udes.edu.coRepositorio Universidad de Santandersoporte@metabiblioteca.comTGljZW5jaWEgZGUgUHVibGljYWNpw7NuIFVERVMKRGlyZWN0cmljZXMgZGUgVVNPIHkgQUNDRVNPCgo= |