Enkephalins and ACTH in the mammalian nervous system

7 p.

Autores:
Duque Díaz, Ewing Rafael
Alvarez Ojeda, Olga
Coveñas, Rafael
Tipo de recurso:
Part of book
Fecha de publicación:
2019
Institución:
Universidad de Santander
Repositorio:
Repositorio Universidad de Santander
Idioma:
eng
OAI Identifier:
oai:repositorio.udes.edu.co:001/3744
Acceso en línea:
https://repositorio.udes.edu.co/handle/001/3744
Palabra clave:
Adrenocorticotropin hormone
Leucine-enkephalin
Methionine-enkephalin
Opioid
Pro-enkephalin
Rights
openAccess
License
Derechos Reservados - Universidad de Santander, 2019
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oai_identifier_str oai:repositorio.udes.edu.co:001/3744
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network_name_str Repositorio Universidad de Santander
repository_id_str
dc.title.eng.fl_str_mv Enkephalins and ACTH in the mammalian nervous system
title Enkephalins and ACTH in the mammalian nervous system
spellingShingle Enkephalins and ACTH in the mammalian nervous system
Adrenocorticotropin hormone
Leucine-enkephalin
Methionine-enkephalin
Opioid
Pro-enkephalin
title_short Enkephalins and ACTH in the mammalian nervous system
title_full Enkephalins and ACTH in the mammalian nervous system
title_fullStr Enkephalins and ACTH in the mammalian nervous system
title_full_unstemmed Enkephalins and ACTH in the mammalian nervous system
title_sort Enkephalins and ACTH in the mammalian nervous system
dc.creator.fl_str_mv Duque Díaz, Ewing Rafael
Alvarez Ojeda, Olga
Coveñas, Rafael
dc.contributor.author.spa.fl_str_mv Duque Díaz, Ewing Rafael
Alvarez Ojeda, Olga
Coveñas, Rafael
dc.subject.proposal.eng.fl_str_mv Adrenocorticotropin hormone
Leucine-enkephalin
Methionine-enkephalin
Opioid
Pro-enkephalin
topic Adrenocorticotropin hormone
Leucine-enkephalin
Methionine-enkephalin
Opioid
Pro-enkephalin
description 7 p.
publishDate 2019
dc.date.accessioned.spa.fl_str_mv 2019-09-19T15:49:39Z
dc.date.available.spa.fl_str_mv 2019-09-19T15:49:39Z
dc.date.issued.spa.fl_str_mv 2019-06-14
dc.type.spa.fl_str_mv Capítulo - Parte de Libro
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dc.identifier.doi.spa.fl_str_mv 10.1016/bs.vh.2019.05.001
dc.identifier.isbn.spa.fl_str_mv 9780128188583
dc.identifier.uri.spa.fl_str_mv https://repositorio.udes.edu.co/handle/001/3744
identifier_str_mv 10.1016/bs.vh.2019.05.001
9780128188583
url https://repositorio.udes.edu.co/handle/001/3744
dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.ispartof.eng.fl_str_mv Opioid Hormones
dc.relation.ispartofseries.eng.fl_str_mv Vitamins and Hormones;Volume 111, 2019, Chapter 7. Pages 147-193
dc.rights.spa.fl_str_mv Derechos Reservados - Universidad de Santander, 2019
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rights_invalid_str_mv Derechos Reservados - Universidad de Santander, 2019
Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)
https://creativecommons.org/licenses/by-nc/4.0/
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eu_rights_str_mv openAccess
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spelling Duque Díaz, Ewing Rafael6745e3c4-626c-457a-b5a2-cad03f7c25d1-1Alvarez Ojeda, Olga11a9b057-2387-4cd3-ac68-2b8a764759f1-1Coveñas, Rafael99a3e7ad-fa30-43b1-893a-9c3d6164eed3-12019-09-19T15:49:39Z2019-09-19T15:49:39Z2019-06-147 p.The pentapeptides methionine-enkephalin and leucine-enkephalin belong to the opioid family of peptides, and the non-opiate peptide adrenocorticotropin hormone (ACTH) to the melanocortin peptide family. Enkephalins/ACTH are derived from pro-enkephalin, pro-dynorphin or pro-opiomelanocortin precursors and, via opioid and melanocortin receptors, are responsible for many biological activities. Enkephalins exhibit the highest affinity for the δ receptor, followed by the μ and κ receptors, whereas ACTH binds to the five subtypes of melanocortin receptor, and is the only member of the melanocortin family of peptides that binds to the melanocortin-receptor 2 (ACTH receptor). Enkephalins/ACTH and their receptors exhibit a widespread anatomical distribution. Enkephalins are involved in analgesia, angiogenesis, blood pressure, embryonic development, emotional behavior, feeding, hypoxia, limbic system modulation, neuroprotection, peristalsis, and wound repair; as well as in hepatoprotective, motor, neuroendocrine and respiratory mechanisms. ACTH plays a role in acetylcholine release, aggressive behavior, blood pressure, bone maintenance, hyperalgesia, feeding, fever, grooming, learning, lipolysis, memory, nerve injury repair, neuroprotection, sexual behavior, sleep, social behavior, tissue growth and stimulates the synthesis and secretion of glucocorticoids. Enkephalins/ACTH are also involved in many pathologies. Enkephalins are implicated in alcoholism, cancer, colitis, depression, heart failure, Huntington's disease, influenza A virus infection, ischemia, multiple sclerosis, and stress. ACTH plays a role in Addison's disease, alcoholism, cancer, Cushing's disease, dermatitis, encephalitis, epilepsy, Graves' disease, Guillain-Barré syndrome, multiple sclerosis, podocytopathies, and stress. In this review, we provide an updated description of the enkephalinergic and ACTH systems.application/pdf10.1016/bs.vh.2019.05.0019780128188583https://repositorio.udes.edu.co/handle/001/3744engOpioid HormonesVitamins and Hormones;Volume 111, 2019, Chapter 7. Pages 147-193Derechos Reservados - Universidad de Santander, 2019info:eu-repo/semantics/openAccessAtribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)https://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2https://www.sciencedirect.com/science/article/pii/S0083672919300378Adrenocorticotropin hormoneLeucine-enkephalinMethionine-enkephalinOpioidPro-enkephalinEnkephalins and ACTH in the mammalian nervous systemCapítulo - Parte de Librohttp://purl.org/coar/resource_type/c_3248Textinfo:eu-repo/semantics/bookParthttps://purl.org/redcol/resource_type/CAP_LIBinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85PublicationORIGINALEnkephalins and ACTH in the mammalian nervous system.pdfEnkephalins and ACTH in the mammalian nervous system.pdfapplication/pdf245068https://repositorio.udes.edu.co/bitstreams/30fe1772-75d0-4919-8065-f5a51879d0cc/download99ccde7da4fd14fb973f760364bfb6faMD54THUMBNAILEnkephalins and ACTH in the mammalian nervous system.PNG.jpgEnkephalins and ACTH in the mammalian nervous system.PNG.jpgGenerated Thumbnailimage/jpeg1316https://repositorio.udes.edu.co/bitstreams/ce3886ef-d549-4d4e-be00-3a8757193d2e/downloadf9c47931544053ca7bb8651121b365f3MD53Enkephalins and ACTH in the mammalian nervous system.pdf.jpgEnkephalins and ACTH in the mammalian nervous system.pdf.jpgGenerated Thumbnailimage/jpeg11121https://repositorio.udes.edu.co/bitstreams/bae5fcd9-cd08-4414-8a9f-cb49cf41d37f/downloadfd509658efcaa049b436b3b717d3513cMD56LICENSElicense.txtlicense.txttext/plain; charset=utf-859https://repositorio.udes.edu.co/bitstreams/5ea1168e-ee58-4f01-9321-53372f431304/download38d94cf55aa1bf2dac1a736ac45c881cMD52TEXTEnkephalins and ACTH in the mammalian nervous system.pdf.txtEnkephalins and ACTH in the mammalian nervous system.pdf.txtExtracted texttext/plain5https://repositorio.udes.edu.co/bitstreams/168e6a90-2160-4c50-bd65-b96b66bad70b/download5dbe86c1111d64f45ba435df98fdc825MD55001/3744oai:repositorio.udes.edu.co:001/37442023-10-10 12:57:19.273https://creativecommons.org/licenses/by-nc/4.0/Derechos Reservados - Universidad de Santander, 2019https://repositorio.udes.edu.coRepositorio Universidad de Santandersoporte@metabiblioteca.comTGljZW5jaWEgZGUgUHVibGljYWNpw7NuIFVERVMKRGlyZWN0cmljZXMgZGUgVVNPIHkgQUNDRVNPCgo=