Availability and affordability of medicines and cardiovascular outcomes in 21 high-income, middle-income and low-income countries

Digital

Autores:
Chow, Clara Kayei
Nguyen, Ngoc
Marschner, Simone
Diaz, Rafael
Rahman, Omar
Avezum, Alvaro
Lear, Scott A.
Teo, Koon
Yeates, Karen
Lanas, Fernando
Li, Wei
Hu, Bo
Lopez-Jaramillo, Patricio
Gupta, Rajeev
Kumar, Rajesh
Mony, Prem
Bahonar, Ahmad
Yusoff, Khalid
Khatib, Rasha
Kazmi, Khawar
Dans, Antonio
Zatonska, Katarzyna
Alhabib, Khalid F.
Kruger, Iolanthe Marike
Rosengren, Annika
Yusufali, Afzalhussein
Chifamba, Jephat
Rangarajan, Sumathy
McKee, Martin
Yusuf, Salim
Tipo de recurso:
Article of journal
Fecha de publicación:
2020
Institución:
Universidad de Santander
Repositorio:
Repositorio Universidad de Santander
Idioma:
eng
OAI Identifier:
oai:repositorio.udes.edu.co:001/6029
Acceso en línea:
http://dx.doi.org/10.1136/ bmjgh-2020-002640
https://repositorio.udes.edu.co/handle/001/6029
Palabra clave:
Rights
openAccess
License
Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)
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dc.title.spa.fl_str_mv Availability and affordability of medicines and cardiovascular outcomes in 21 high-income, middle-income and low-income countries
title Availability and affordability of medicines and cardiovascular outcomes in 21 high-income, middle-income and low-income countries
spellingShingle Availability and affordability of medicines and cardiovascular outcomes in 21 high-income, middle-income and low-income countries
title_short Availability and affordability of medicines and cardiovascular outcomes in 21 high-income, middle-income and low-income countries
title_full Availability and affordability of medicines and cardiovascular outcomes in 21 high-income, middle-income and low-income countries
title_fullStr Availability and affordability of medicines and cardiovascular outcomes in 21 high-income, middle-income and low-income countries
title_full_unstemmed Availability and affordability of medicines and cardiovascular outcomes in 21 high-income, middle-income and low-income countries
title_sort Availability and affordability of medicines and cardiovascular outcomes in 21 high-income, middle-income and low-income countries
dc.creator.fl_str_mv Chow, Clara Kayei
Nguyen, Ngoc
Marschner, Simone
Diaz, Rafael
Rahman, Omar
Avezum, Alvaro
Lear, Scott A.
Teo, Koon
Yeates, Karen
Lanas, Fernando
Li, Wei
Hu, Bo
Lopez-Jaramillo, Patricio
Gupta, Rajeev
Kumar, Rajesh
Mony, Prem
Bahonar, Ahmad
Yusoff, Khalid
Khatib, Rasha
Kazmi, Khawar
Dans, Antonio
Zatonska, Katarzyna
Alhabib, Khalid F.
Kruger, Iolanthe Marike
Rosengren, Annika
Yusufali, Afzalhussein
Chifamba, Jephat
Rangarajan, Sumathy
McKee, Martin
Yusuf, Salim
dc.contributor.author.none.fl_str_mv Chow, Clara Kayei
Nguyen, Ngoc
Marschner, Simone
Diaz, Rafael
Rahman, Omar
Avezum, Alvaro
Lear, Scott A.
Teo, Koon
Yeates, Karen
Lanas, Fernando
Li, Wei
Hu, Bo
Lopez-Jaramillo, Patricio
Gupta, Rajeev
Kumar, Rajesh
Mony, Prem
Bahonar, Ahmad
Yusoff, Khalid
Khatib, Rasha
Kazmi, Khawar
Dans, Antonio
Zatonska, Katarzyna
Alhabib, Khalid F.
Kruger, Iolanthe Marike
Rosengren, Annika
Yusufali, Afzalhussein
Chifamba, Jephat
Rangarajan, Sumathy
McKee, Martin
Yusuf, Salim
dc.contributor.researchgroup.spa.fl_str_mv Masira
description Digital
publishDate 2020
dc.date.issued.none.fl_str_mv 2020-11-05
dc.date.accessioned.none.fl_str_mv 2022-02-17T15:09:24Z
dc.date.available.none.fl_str_mv 2022-02-17T15:09:24Z
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dc.language.iso.spa.fl_str_mv eng
language eng
dc.relation.citationendpage.spa.fl_str_mv 10
dc.relation.citationissue.spa.fl_str_mv 11
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dc.relation.cites.none.fl_str_mv Chow CK, Nguyen TN, Marschner S, et al. Availability and affordability of medicines and cardiovascular outcomes in 21 high-income, middleincome and low-income countries. BMJ Global Health 2020;5:e002640. doi:10.1136/ bmjgh-2020-002640
dc.relation.indexed.spa.fl_str_mv Scopus
dc.relation.ispartofjournal.spa.fl_str_mv BMJ Global Health
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eu_rights_str_mv openAccess
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dc.publisher.place.spa.fl_str_mv Reino Unido
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spelling Chow, Clara Kayeid389d892-ccad-455f-8f6e-9b6529146f5a-1Nguyen, Ngocda765c87-0d0e-4e85-a235-458398cfd218-1Marschner, Simone2ce2f8e8-676d-454f-a297-e330740f8649-1Diaz, Rafaelf2be4a74-501a-4e63-8bbd-965cbcf8c57b-1Rahman, Omar2fdf224c-97c9-4fb0-b7a9-ea79427bc631-1Avezum, Alvaro8b920360-abb2-4ec8-b5ee-4e3f4e0b11eb-1Lear, Scott A.19eb29a4-5987-41b9-a400-130692ec0232-1Teo, Koon60475883-56ab-4acc-833d-b027ad828534-1Yeates, Karen79418492-ec06-4cc6-831a-4bf5b245b584-1Lanas, Fernandod22b7fe4-9f1f-4028-a22b-be782ef03d3c-1Li, Wei16f14ef2-1a33-4354-93fe-e8d6d1ae09b7-1Hu, Bobec2821d-8ea9-4783-b64e-5fc592117452-1Lopez-Jaramillo, Patricio9a71267b-dcb0-4d31-b37d-2d30be58d4d2-1Gupta, Rajeevde1826df-aac8-4d9f-9b84-f21ba704686c-1Kumar, Rajesh649d5d1b-c303-4964-9ed4-657eb4a715df-1Mony, Premab6dbf82-20a0-4744-abfd-8a723db46c4d-1Bahonar, Ahmad0f7df84f-12df-494e-9416-c33d4b5fedbe-1Yusoff, Khalid933db13d-f5bb-4ea6-91a5-68eea1ca9ffc-1Khatib, Rasha7beae0a6-cfd5-4272-bf8c-1b5896fed8e5-1Kazmi, Khawar69af1dac-e1e0-45dd-91e9-6add426eb64e-1Dans, Antoniof365ef5a-7610-4022-8485-31d6d3879cd6-1Zatonska, Katarzyna6d84170f-b69c-462b-9d93-3f363491580a-1Alhabib, Khalid F.84dc113a-dcf3-43f0-adec-af4dabb61538-1Kruger, Iolanthe Marike4a97c272-1f00-4818-9548-1a0909ef3aea-1Rosengren, Annika923779f9-3a92-4086-b3d9-9d78974926d9-1Yusufali, Afzalhussein2c177fd9-b761-4f07-b754-1e05fe659a48-1Chifamba, Jephatf2496279-e934-40b8-8f61-0039a09f03f8-1Rangarajan, Sumathy5466c363-e515-4bd2-8537-eb839320f385-1McKee, Martin5258b372-6b7d-4e6f-aaa6-0e81538245af-1Yusuf, Salim06a836b5-f5e3-41d9-a516-9cc46e5d7948-1Masira2022-02-17T15:09:24Z2022-02-17T15:09:24Z2020-11-05DigitalObjectives We aimed to examine the relationship between access to medicine for cardiovascular disease (CVD) and major adverse cardiovascular events (MACEs) among people at high risk of CVD in high-income countries (HICs), upper and lower middle-income countries (UMICs, LMICs) and low-income countries (LICs) participating in the Prospective Urban Rural Epidemiology (PURE) study. Methods We defined high CVD risk as the presence of any of the following: hypertension, coronary artery disease, stroke, smoker, diabetes or age >55 years. Availability and affordability of blood pressure lowering drugs, antiplatelets and statins were obtained from pharmacies. Participants were categorised: group 1—all three drug types were available and affordable, group 2—all three drugs were available but not affordable and group 3—all three drugs were not available. We used multivariable Cox proportional hazard models with nested clustering at country and community levels, adjusting for comorbidities, sociodemographic and economic factors. Results Of 163 466 participants, there were 93 200 with high CVD risk from 21 countries (mean age 54.7,49% female). Of these, 44.9% were from group 1, 29.4% from group 2 and 25.7% from group 3. Compared with participants from group 1, the risk of MACEs was higher among participants in group 2 (HR 1.19, 95% CI 1.07 to 1.31), and among participants from group 3 (HR 1.25, 95% CI 1.08 to 1.50). Conclusion Lower availability and affordability of essential CVD medicines were associated with higher risk of MACEs and mortality. Improving access to CVD medicines should be a key part of the strategy to lower CVD globally.Ciencias Médicas y de la Salud10 papplication/pdfhttp://dx.doi.org/10.1136/ bmjgh-2020-002640https://repositorio.udes.edu.co/handle/001/6029engBMJ JournalsReino Unido101115Chow CK, Nguyen TN, Marschner S, et al. Availability and affordability of medicines and cardiovascular outcomes in 21 high-income, middleincome and low-income countries. BMJ Global Health 2020;5:e002640. doi:10.1136/ bmjgh-2020-002640ScopusBMJ Global Health© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.info:eu-repo/semantics/openAccessAtribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)https://creativecommons.org/licenses/by/4.0/http://purl.org/coar/access_right/c_abf2https://gh.bmj.com/content/bmjgh/5/11/e002640.full.pdfAvailability and affordability of medicines and cardiovascular outcomes in 21 high-income, middle-income and low-income countriesArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85Todas las AudienciasPublicationORIGINALAvailability and affordability of medicines and cardiovascular outcomes in 21 high-income, middle-income and low-income countries.pdfAvailability and affordability of medicines and cardiovascular outcomes in 21 high-income, middle-income and low-income countries.pdfapplication/pdf241315https://repositorio.udes.edu.co/bitstreams/6585923a-e6be-45a3-88c1-77dc6c65c434/download6787c06211f27a4b9456b91fca6380efMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-859https://repositorio.udes.edu.co/bitstreams/d8f0566d-2b51-4ae7-a136-b12879fe4ea5/download38d94cf55aa1bf2dac1a736ac45c881cMD52TEXTAvailability and affordability of medicines and cardiovascular outcomes in 21 high-income, middle-income and low-income countries.pdf.txtAvailability and affordability of medicines and cardiovascular outcomes in 21 high-income, middle-income and low-income countries.pdf.txtExtracted texttext/plain5https://repositorio.udes.edu.co/bitstreams/33268571-e2b6-431c-b7ae-a442935d7079/download5dbe86c1111d64f45ba435df98fdc825MD53THUMBNAILAvailability and affordability of medicines and cardiovascular outcomes in 21 high-income, middle-income and low-income countries.pdf.jpgAvailability and affordability of medicines and cardiovascular outcomes in 21 high-income, middle-income and low-income countries.pdf.jpgGenerated Thumbnailimage/jpeg12285https://repositorio.udes.edu.co/bitstreams/daa0299e-b514-49a5-b464-66e4122ddd9d/download2ba07ab2c7ea6e1d268c1a26e3701e78MD54001/6029oai:repositorio.udes.edu.co:001/60292023-10-09 18:09:36.525https://creativecommons.org/licenses/by/4.0/© Author(s) (or their employer(s)) 2020. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.https://repositorio.udes.edu.coRepositorio Universidad de Santandersoporte@metabiblioteca.comTGljZW5jaWEgZGUgUHVibGljYWNpw7NuIFVERVMKRGlyZWN0cmljZXMgZGUgVVNPIHkgQUNDRVNPCgo=