Peroxisome proliferator-activated receptor delta-PPARδ agonist (L-165041) enhances bovine embryo survival and post vitrification viability
Digital
- Autores:
-
Sanchez-Viafara, Jesus Alfonso
Lopes de Vasconcelos, Gisvani
Maculan, Renata
Gomes Alves, Nadja
Dias-Ferreira, Marcos Brandao
Sudano, Mateus Jose
Zoccal-Mingoti, Gisele
Barros-Nunes, Giovana
Ribeiro de Lima, Renato
Martins-Drumond, Roberti
Nunes-Dos Santos, Raphael
Nogueira-Eberlin, Marcos
Negrão, Fernanda
Jasmin
Aragão-M. Donato, Mariana
Peixoto, Christina A.
Camisão de Souza, Jose
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2022
- Institución:
- Universidad de Santander
- Repositorio:
- Repositorio Universidad de Santander
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.udes.edu.co:001/7331
- Palabra clave:
- Bovine
Cryopreservation
Culture Medium
Development
Embryo Apoptosis
Embryos
Lipid
Vitrification
- Rights
- closedAccess
- License
- © 2022 The Author(s) (or their employer(s)). Published by CSIRO Publishing
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Peroxisome proliferator-activated receptor delta-PPARδ agonist (L-165041) enhances bovine embryo survival and post vitrification viability |
| title |
Peroxisome proliferator-activated receptor delta-PPARδ agonist (L-165041) enhances bovine embryo survival and post vitrification viability |
| spellingShingle |
Peroxisome proliferator-activated receptor delta-PPARδ agonist (L-165041) enhances bovine embryo survival and post vitrification viability Bovine Cryopreservation Culture Medium Development Embryo Apoptosis Embryos Lipid Vitrification |
| title_short |
Peroxisome proliferator-activated receptor delta-PPARδ agonist (L-165041) enhances bovine embryo survival and post vitrification viability |
| title_full |
Peroxisome proliferator-activated receptor delta-PPARδ agonist (L-165041) enhances bovine embryo survival and post vitrification viability |
| title_fullStr |
Peroxisome proliferator-activated receptor delta-PPARδ agonist (L-165041) enhances bovine embryo survival and post vitrification viability |
| title_full_unstemmed |
Peroxisome proliferator-activated receptor delta-PPARδ agonist (L-165041) enhances bovine embryo survival and post vitrification viability |
| title_sort |
Peroxisome proliferator-activated receptor delta-PPARδ agonist (L-165041) enhances bovine embryo survival and post vitrification viability |
| dc.creator.fl_str_mv |
Sanchez-Viafara, Jesus Alfonso Lopes de Vasconcelos, Gisvani Maculan, Renata Gomes Alves, Nadja Dias-Ferreira, Marcos Brandao Sudano, Mateus Jose Zoccal-Mingoti, Gisele Barros-Nunes, Giovana Ribeiro de Lima, Renato Martins-Drumond, Roberti Nunes-Dos Santos, Raphael Nogueira-Eberlin, Marcos Negrão, Fernanda Jasmin Aragão-M. Donato, Mariana Peixoto, Christina A. Camisão de Souza, Jose |
| dc.contributor.author.none.fl_str_mv |
Sanchez-Viafara, Jesus Alfonso Lopes de Vasconcelos, Gisvani Maculan, Renata Gomes Alves, Nadja Dias-Ferreira, Marcos Brandao Sudano, Mateus Jose Zoccal-Mingoti, Gisele Barros-Nunes, Giovana Ribeiro de Lima, Renato Martins-Drumond, Roberti Nunes-Dos Santos, Raphael Nogueira-Eberlin, Marcos Negrão, Fernanda Jasmin Aragão-M. Donato, Mariana Peixoto, Christina A. Camisão de Souza, Jose |
| dc.contributor.researchgroup.spa.fl_str_mv |
Ciencias UDES |
| dc.subject.proposal.eng.fl_str_mv |
Bovine Cryopreservation Culture Medium Development Embryo Apoptosis Embryos Lipid Vitrification |
| topic |
Bovine Cryopreservation Culture Medium Development Embryo Apoptosis Embryos Lipid Vitrification |
| description |
Digital |
| publishDate |
2022 |
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2022-08-03T15:22:18Z |
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2022-08-03T15:22:18Z |
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2022-05-22 |
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Artículo de revista |
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https://doi.org/10.1071/RD21245 |
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1448-5990 |
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1031-3613 |
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https://repositorio.udes.edu.co/handle/001/7331 |
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eng |
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eng |
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Sánchez Viafara Jesús Alfonso, de Vasconcelos Gisvani Lopes, Maculan Renata, Alves Nadja Gomes, Ferreira Marcos Brandao Dias, Sudano Mateus José, Mingoti Gisele Zoccal, Nunes Giovana Barros, de Lima Renato Ribeiro, Drumond Roberti Martins, dos Santos Raphael Nunes, Eberlin Marcos Nogueira, Negrão Fernanda, Jasmin , Donato Mariana Aragão M., Peixoto Christina A., Camisão de Souza José (2022) Peroxisome proliferator-activated receptor delta-PPARδ agonist (L-165041) enhances bovine embryo survival and post vitrification viability. Reproduction, Fertility and Development 34, 658-668. https://doi.org/10.1071/RD21245 |
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Scopus |
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Reproduction, Fertility and Development |
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© 2022 The Author(s) (or their employer(s)). Published by CSIRO Publishing |
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Sanchez-Viafara, Jesus Alfonso0ef3ade0-1d8e-4f10-b3b9-3005dab5f838-1Lopes de Vasconcelos, Gisvani44818efb-6b8f-41f2-bd65-30c185018063-1Maculan, Renataa4489753-60dd-483d-9006-2a62a594e2f4-1Gomes Alves, Nadjaf7217ddc-e3ce-4b3e-bce1-c6c54f82a9cf-1Dias-Ferreira, Marcos Brandao8a351131-697a-4d64-8e5a-0fb23dcb7338-1Sudano, Mateus Jose84e9f26a-72d2-48eb-bdcb-5246c1e5cc43-1Zoccal-Mingoti, Gisele3157b11c-d4b5-4314-88db-083444685cfc-1Barros-Nunes, Giovana14c0c896-c8e3-482f-bf88-d1a9eec647b5-1Ribeiro de Lima, Renato39880445-6f0a-4e96-82ce-d6887f9ced7f-1Martins-Drumond, Robertica5501d7-082d-46b5-b2e2-0c22c03db99e-1Nunes-Dos Santos, Raphael98ae298b-28b2-4045-8bdb-31b91e08f424-1Nogueira-Eberlin, Marcos3cc01dec-fa34-4868-b9a0-f0538be9a8b2-1Negrão, Fernandaf6d0e06e-aae9-4345-8b3a-6a02aa61f6df-1Jasminb8702a17-6f91-4d1e-9bb8-56a331ed7aab-1Aragão-M. Donato, Mariana5482b2d6-760d-4002-aac1-9bccb80ff67d-1Peixoto, Christina A.3f72187f-faea-47c3-a4ab-05d5266afcdd-1Camisão de Souza, Jose16b26f80-1795-4d7d-a6e6-b7b800c8431d-1Ciencias UDES2022-08-03T15:22:18Z2022-08-03T15:22:18Z2022-05-22DigitalThe effect of L-165041 (PPARδ-agonist) on decreasing apoptosis and intracellular lipid content was assessed in fresh and vitrified–warmed in vitro-produced bovine embryos. It was hypothesised that the addition of L-165041 to the culture medium enhances development and cryopreservation. Oocytes were allocated to one of two treatments: control-standard culture medium, or L-165041 added to the medium on day 1 with no media change. Ultrastructure, cleavage, and blastocyst rates were evaluated in fresh, and in post-vitrification cultured embryos by optical and electronic microscopy. A subset of fresh embryos were fixed for TUNEL assay and for Sudan-Black-B histochemical staining. Vitrified–warmed embryos were assessed using MALDI-MS technique. Cleavage and blastocyst rates (control 49.4 ± 5.2, L-165041 51.8 ± 4.3) were not influenced by L-165041. The proportion of inner cell mass cells (ICM) was higher in fresh embryos, and the rate of total and ICM apoptosis was lower in L-165041. In warmed-embryos, total and ICM apoptosis was lower in L-165041. The overall hatching rate was higher in L-165041 (66.62 ± 2.83% vs 53.19 ± 2.90%). There was less lipid accumulation in fresh L-165041-embryos. In conclusion, the use of L-165041 is recommended to improve the viability of in vitro-derived bovine embryos.Ciencias Agropecuariasapplication/pdfhttps://doi.org/10.1071/RD212451448-59901031-3613https://repositorio.udes.edu.co/handle/001/7331engAustralia668965834Sánchez Viafara Jesús Alfonso, de Vasconcelos Gisvani Lopes, Maculan Renata, Alves Nadja Gomes, Ferreira Marcos Brandao Dias, Sudano Mateus José, Mingoti Gisele Zoccal, Nunes Giovana Barros, de Lima Renato Ribeiro, Drumond Roberti Martins, dos Santos Raphael Nunes, Eberlin Marcos Nogueira, Negrão Fernanda, Jasmin , Donato Mariana Aragão M., Peixoto Christina A., Camisão de Souza José (2022) Peroxisome proliferator-activated receptor delta-PPARδ agonist (L-165041) enhances bovine embryo survival and post vitrification viability. Reproduction, Fertility and Development 34, 658-668. https://doi.org/10.1071/RD21245ScopusReproduction, Fertility and Development© 2022 The Author(s) (or their employer(s)). 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