Smell status in functional movement disorders : New clues for diagnosis and underlying mechanisms
5 p.
- Autores:
-
Leon Sarmiento, Fidias E.
Bayona Prieto, Jaime
Leon Ariza, Juan S.
Leon Ariza, Daniel S.
Jacob, Alexandra E.
LaFaver, Kathrin
Doty, Richard L.
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2019
- Institución:
- Universidad de Santander
- Repositorio:
- Repositorio Universidad de Santander
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.udes.edu.co:001/3108
- Acceso en línea:
- https://repositorio.udes.edu.co/handle/001/3108
- Palabra clave:
- Functional movement disorders
Psychogenic disorders
Smell
Parkinson’s disease
Acetylcholine
- Rights
- openAccess
- License
- Rights - Elsevier B.V., 2019
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Smell status in functional movement disorders : New clues for diagnosis and underlying mechanisms |
| title |
Smell status in functional movement disorders : New clues for diagnosis and underlying mechanisms |
| spellingShingle |
Smell status in functional movement disorders : New clues for diagnosis and underlying mechanisms Functional movement disorders Psychogenic disorders Smell Parkinson’s disease Acetylcholine |
| title_short |
Smell status in functional movement disorders : New clues for diagnosis and underlying mechanisms |
| title_full |
Smell status in functional movement disorders : New clues for diagnosis and underlying mechanisms |
| title_fullStr |
Smell status in functional movement disorders : New clues for diagnosis and underlying mechanisms |
| title_full_unstemmed |
Smell status in functional movement disorders : New clues for diagnosis and underlying mechanisms |
| title_sort |
Smell status in functional movement disorders : New clues for diagnosis and underlying mechanisms |
| dc.creator.fl_str_mv |
Leon Sarmiento, Fidias E. Bayona Prieto, Jaime Leon Ariza, Juan S. Leon Ariza, Daniel S. Jacob, Alexandra E. LaFaver, Kathrin Doty, Richard L. |
| dc.contributor.author.spa.fl_str_mv |
Leon Sarmiento, Fidias E. Bayona Prieto, Jaime Leon Ariza, Juan S. Leon Ariza, Daniel S. Jacob, Alexandra E. LaFaver, Kathrin Doty, Richard L. |
| dc.subject.proposal.eng.fl_str_mv |
Functional movement disorders Psychogenic disorders Smell Parkinson’s disease Acetylcholine |
| topic |
Functional movement disorders Psychogenic disorders Smell Parkinson’s disease Acetylcholine |
| description |
5 p. |
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2019 |
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2019-06-18T16:04:10Z |
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2019 |
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10.1016/j.clineuro.2018.12.017 |
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0303-8467 1872-6968 |
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https://repositorio.udes.edu.co/handle/001/3108 |
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10.1016/j.clineuro.2018.12.017 0303-8467 1872-6968 |
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eng |
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eng |
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Clinical Neurology and Neurosurgery |
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Rights - Elsevier B.V., 2019 |
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openAccess |
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application/pdf |
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https://www.sciencedirect.com/science/article/pii/S1440244018304389?via%3Dihub |
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Leon Sarmiento, Fidias E.46042405-eca5-442f-84ba-2f81d90d50b5-1Bayona Prieto, Jaime518d69f2-dc09-4a29-b58a-380f4c829d7e-1Leon Ariza, Juan S.1d9c7815-4d9d-4d10-b3ab-1adaffa2c3d8-1Leon Ariza, Daniel S.376c7434-3d7f-451a-ac99-8b1be55d3bde-1Jacob, Alexandra E.e5e253b3-f8a1-4715-899c-e2615e4a20f2-1LaFaver, Kathrin94488752-e33f-4c2a-87fa-5058ba65a7d7-1Doty, Richard L.bde89071-8192-4e6a-80e7-35b395629a1e-12019-06-18T16:04:10Z2019-06-18T16:04:10Z20195 p.Objective: Functional movement disorders (FMDs) mimic a range of movements, neuropsychiatric and neurodegenerative disorders known to have smell dysfunction, which has been neglected in terms of its application to FMD. We aim to determine the smell status in FMD patients tested by a non-invasive, reliable and validated olfactory test. Patients and methods: We quantitatively assessed in thirty-five FMD patients their smell status and compared it to that of healthy age- and sex-matched controls, and of patients with Parkinson’s disease (PD). All participants were administered the Brief Smell Identification Test (B-SIT), a standardized short version of the University of Pennsylvania Smell Identification Test (UPSIT). The Picture Identification Test (PIT), a visual test analogous in content and form to the UPSIT designed to control for non-olfactory cognitive confounds, was also administered. Results: The B-SIT scores of the FMD patients were higher than those from PD patients [respective means (standard deviations: SDs) = FMD, 9.54 (1.57); PD, 4.64 (1.05), p < 0.01)] but similar to the smell scores from healthy controls [9.97 (1.77), p=0.35]. Gender, age, time of disease onset, smoking status, and phenotypic expression did not influence the test scores. Fourteen FMD patients who mentioned having olfactory dysfunction before smell testing have their test results within normal range. PIT scores from patients and healthy controls were within normal range. Conclusions: These findings indicate that FMD patients have normal olfactory function. Olfactory testing may be helpful in identifying and differentiating FMD from other movement, neurodegenerative and neuropsychiatric diseases for which smell function is altered.application/pdf10.1016/j.clineuro.2018.12.0170303-84671872-6968https://repositorio.udes.edu.co/handle/001/3108engClinical Neurology and NeurosurgeryRights - Elsevier B.V., 2019info:eu-repo/semantics/openAccessAtribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)https://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2https://www.sciencedirect.com/science/article/pii/S1440244018304389?via%3DihubFunctional movement disordersPsychogenic disordersSmellParkinson’s diseaseAcetylcholineSmell status in functional movement disorders : New clues for diagnosis and underlying mechanismsArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85PublicationBRANDED_PREVIEWSmell status in functional movement disorders. 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