Case-Control Pilot Study on Acute Diarrheal Disease in a Geographically Defined Pediatric Population in a Middle Income Country
1 p.
- Autores:
-
Farfán García, Ana Elvira
Zhang, Chengxian
Imdad, Aamer
Arias Guerrero, Monica Y.
Sánchez Álvarez, Nayibe T.
Shah, Rikhil
Iqbal, Junaid
Tamborski, Maria E.
Gómez-Duarte, Oscar G.
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2017
- Institución:
- Universidad de Santander
- Repositorio:
- Repositorio Universidad de Santander
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.udes.edu.co:001/4694
- Acceso en línea:
- https://doi.org/10.1155/2017/6357597
https://repositorio.udes.edu.co/handle/001/4694
- Palabra clave:
- Acute Diarrheal Disease
Pediatric Population
- Rights
- restrictedAccess
- License
- Derechos Reservados - Ana E. Farfán-García et al., 2017.
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Case-Control Pilot Study on Acute Diarrheal Disease in a Geographically Defined Pediatric Population in a Middle Income Country |
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Case-Control Pilot Study on Acute Diarrheal Disease in a Geographically Defined Pediatric Population in a Middle Income Country |
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Case-Control Pilot Study on Acute Diarrheal Disease in a Geographically Defined Pediatric Population in a Middle Income Country Acute Diarrheal Disease Pediatric Population |
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Case-Control Pilot Study on Acute Diarrheal Disease in a Geographically Defined Pediatric Population in a Middle Income Country |
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Case-Control Pilot Study on Acute Diarrheal Disease in a Geographically Defined Pediatric Population in a Middle Income Country |
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Case-Control Pilot Study on Acute Diarrheal Disease in a Geographically Defined Pediatric Population in a Middle Income Country |
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Case-Control Pilot Study on Acute Diarrheal Disease in a Geographically Defined Pediatric Population in a Middle Income Country |
| dc.creator.fl_str_mv |
Farfán García, Ana Elvira Zhang, Chengxian Imdad, Aamer Arias Guerrero, Monica Y. Sánchez Álvarez, Nayibe T. Shah, Rikhil Iqbal, Junaid Tamborski, Maria E. Gómez-Duarte, Oscar G. |
| dc.contributor.author.spa.fl_str_mv |
Farfán García, Ana Elvira Zhang, Chengxian Imdad, Aamer Arias Guerrero, Monica Y. Sánchez Álvarez, Nayibe T. Shah, Rikhil Iqbal, Junaid Tamborski, Maria E. Gómez-Duarte, Oscar G. |
| dc.contributor.corporatename.spa.fl_str_mv |
Universidad de Santander |
| dc.contributor.subjectmatterexpert.eng.fl_str_mv |
Hans Juergen Laws |
| dc.subject.proposal.eng.fl_str_mv |
Acute Diarrheal Disease Pediatric Population |
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Acute Diarrheal Disease Pediatric Population |
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1 p. |
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2017 |
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2017-08-10 |
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2020-08-20T15:03:08Z |
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eng |
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eng |
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International Journal of Pediatrics |
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International Journal of Pediatrics;Volume 2017 |
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Derechos Reservados - Ana E. Farfán-García et al., 2017. |
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New York : Hindawi, 2017 |
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Farfán García, Ana Elvira74472815-bd1a-4bf4-932b-0264dd209268-1Zhang, Chengxiana524736f-1323-48cb-bc34-f0769a860493-1Imdad, Aamer46e95bf9-25a0-4af3-b643-50f85632a518-1Arias Guerrero, Monica Y.fbe9fbec-6d65-4d41-ab10-b70116adf78f-1Sánchez Álvarez, Nayibe T.4473292c-3c6c-44ba-80f5-25f619f2910f-1Shah, Rikhil4d01322c-6532-4fe6-8a30-97a3f557f0d8-1Iqbal, Junaidc7776124-d30d-4152-ac43-a935d08d9770-1Tamborski, Maria E.4cfd2b2d-4c6e-433f-b3b7-bfeaabbbb373-1Gómez-Duarte, Oscar G.a2dbbaaf-ccc7-43db-96d4-f7d083ad619e-1Universidad de SantanderHans Juergen Laws2020-08-20T15:03:08Z2020-08-20T15:03:08Z2017-08-101 p.La enfermedad diarreica aguda (EDA) es una causa común de morbilidad y mortalidad en los niños menores de 5 años. En la mayoría de los países de ingresos bajos y medios no se comprende la etiología del TDA porque los laboratorios de referencia detectan un número limitado de patógenos . El objetivo de este estudio fue determinar la viabilidad de realizar un estudio integral de casos y controles para examinar los patógenos diarreicos entre los niños con y sin TDA de moderado a grave. Materiales y métodos. Se utilizaron técnicas microbiológicas y moleculares para detectar enteropatógenos virales, bacterianos y parasitarios. El estudio se realizó en Bucaramanga, Colombia, luego de obtener la aprobación del Comité de Revisión Institucional. Resultados.Se reclutaron noventa niños menores de 5 años después de obtener un consentimiento informado por escrito de los padres o tutores. Cuarenta y cinco sujetos sirvieron como casos con ADD y 45 como controles. Treinta y seis sujetos de 90 (40,0%) fueron positivos para al menos un enteropatógeno, es decir, 20 (44,4%) casos y 16 (35,5%) controles. Conclusiones. Los tres patógenos entéricos más comunes fueron E. coli enteroagregativa (10.0%), Norovirus (6.7%) y Salmonella spp. (5,6%). Los patógenos de E. coli fueron el 18,8% de todas las infecciones, lo que los convierte en los patógenos más frecuentes. La mitad de los casos de TDA fueron negativos para cualquier patógeno.Acute diarrheal disease (ADD) is a common cause of morbidity and mortality in children under 5 years of age. Understanding of the etiology of ADD is lacking in most low and middle income countries because reference laboratories detect limited number of pathogens. The objective of this study was to determine the feasibility to conduct a comprehensive casecontrol study to survey diarrheal pathogens among children with and without moderate-to-severe ADD. Materials and Methods. Microbiology and molecular-based techniques were used to detect viral, bacterial, and parasitic enteropathogens. The study was conducted in Bucaramanga, Colombia, after Institutional Review Board approval was obtained. Results. Ninety children less than 5 years of age were recruited after a written informed consent was obtained from parents or guardians. Forty-five subjects served as cases with ADD and 45 as controls. Thirty-six subjects out of 90 (40.0%) were positive for at least one enteropathogen, that is, 20 (44.4%) cases and 16 (35.5%) controls. Conclusions. The three most common enteric pathogens were enteroaggregative E. coli (10.0%), Norovirus (6.7%), and Salmonella spp. (5.6%). The E. coli pathogens were 18.8% of all infections making them the most frequent pathogens. Half of ADD cases were negative for any pathogens.Ej. 1application/pdfhttps://doi.org/10.1155/2017/6357597https://repositorio.udes.edu.co/handle/001/4694engNew York : Hindawi, 2017International Journal of PediatricsInternational Journal of Pediatrics;Volume 2017Derechos Reservados - Ana E. Farfán-García et al., 2017.info:eu-repo/semantics/restrictedAccessAtribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)https://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_16echttps://www.hindawi.com/journals/ijpedi/2017/6357597/Acute Diarrheal DiseasePediatric PopulationCase-Control Pilot Study on Acute Diarrheal Disease in a Geographically Defined Pediatric Population in a Middle Income CountryArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85PublicationORIGINALCase-Control Pilot Study on Acute Diarrheal Disease in a Geographically Defined Pediatric Population in a Middle Income Country.pdfCase-Control Pilot Study on Acute Diarrheal Disease in a Geographically Defined Pediatric Population in a Middle Income Country.pdfapplication/pdf275129https://repositorio.udes.edu.co/bitstreams/dc54feb4-b874-4600-9c65-e31fe704839d/downloadea46b0c13d23bbc996c9d67488ded25cMD51LICENSElicense.txtlicense.txttext/plain; charset=utf-859https://repositorio.udes.edu.co/bitstreams/a66af6fe-cc1a-4669-938e-78bf2071e49a/download38d94cf55aa1bf2dac1a736ac45c881cMD52TEXTCase-Control Pilot Study on Acute Diarrheal Disease in a Geographically Defined Pediatric Population in a Middle Income Country.pdf.txtCase-Control Pilot Study on Acute Diarrheal Disease in a Geographically Defined Pediatric Population in a Middle Income Country.pdf.txtExtracted texttext/plain5https://repositorio.udes.edu.co/bitstreams/5e4c62b2-2fa9-43d5-b2ca-1e1a0754a8e9/download5dbe86c1111d64f45ba435df98fdc825MD53THUMBNAILCase-Control Pilot Study on Acute Diarrheal Disease in a Geographically Defined Pediatric Population in a Middle Income Country.pdf.jpgCase-Control Pilot Study on Acute Diarrheal Disease in a Geographically Defined Pediatric Population in a Middle Income Country.pdf.jpgGenerated Thumbnailimage/jpeg11298https://repositorio.udes.edu.co/bitstreams/6bec7a65-17fb-4b78-b9bb-9c7a10f5c05e/download2b3f9560cd0d27b79a73118293e12f23MD54001/4694oai:repositorio.udes.edu.co:001/46942023-10-10 09:38:43.303https://creativecommons.org/licenses/by-nc/4.0/Derechos Reservados - Ana E. 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