The presence of abdominal obesity is associated with changes in vascular function independently of other cardiovascular risk factors
10 p.
- Autores:
-
Rueda Clausen, Christian F.
Lahera, Vicente
Calderón, Jaime
Bolivar, Isabel Cristina
Castillo, Victor R.
Gutiérrez, Melquisedec
Carreño, Marisol
Oubiña, Maria del Pilar
Cachofeiro, Victoria
Lopez-Jaramillo, Patricio
- Tipo de recurso:
- Article of journal
- Fecha de publicación:
- 2010
- Institución:
- Universidad de Santander
- Repositorio:
- Repositorio Universidad de Santander
- Idioma:
- eng
- OAI Identifier:
- oai:repositorio.udes.edu.co:001/3677
- Acceso en línea:
- https://repositorio.udes.edu.co/handle/001/3677
- Palabra clave:
- Abdominal obesity
Leptin
Adiponectin
Vascular reactivity
Inflammation
Coronary artery bypass graft
Internal mammary artery
- Rights
- openAccess
- License
- Derechos Reservados - International Journal of Cardiology, 2010
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| dc.title.eng.fl_str_mv |
The presence of abdominal obesity is associated with changes in vascular function independently of other cardiovascular risk factors |
| title |
The presence of abdominal obesity is associated with changes in vascular function independently of other cardiovascular risk factors |
| spellingShingle |
The presence of abdominal obesity is associated with changes in vascular function independently of other cardiovascular risk factors Abdominal obesity Leptin Adiponectin Vascular reactivity Inflammation Coronary artery bypass graft Internal mammary artery |
| title_short |
The presence of abdominal obesity is associated with changes in vascular function independently of other cardiovascular risk factors |
| title_full |
The presence of abdominal obesity is associated with changes in vascular function independently of other cardiovascular risk factors |
| title_fullStr |
The presence of abdominal obesity is associated with changes in vascular function independently of other cardiovascular risk factors |
| title_full_unstemmed |
The presence of abdominal obesity is associated with changes in vascular function independently of other cardiovascular risk factors |
| title_sort |
The presence of abdominal obesity is associated with changes in vascular function independently of other cardiovascular risk factors |
| dc.creator.fl_str_mv |
Rueda Clausen, Christian F. Lahera, Vicente Calderón, Jaime Bolivar, Isabel Cristina Castillo, Victor R. Gutiérrez, Melquisedec Carreño, Marisol Oubiña, Maria del Pilar Cachofeiro, Victoria Lopez-Jaramillo, Patricio |
| dc.contributor.author.spa.fl_str_mv |
Rueda Clausen, Christian F. Lahera, Vicente Calderón, Jaime Bolivar, Isabel Cristina Castillo, Victor R. Gutiérrez, Melquisedec Carreño, Marisol Oubiña, Maria del Pilar Cachofeiro, Victoria Lopez-Jaramillo, Patricio |
| dc.subject.proposal.eng.fl_str_mv |
Abdominal obesity Leptin Adiponectin Vascular reactivity Inflammation Coronary artery bypass graft Internal mammary artery |
| topic |
Abdominal obesity Leptin Adiponectin Vascular reactivity Inflammation Coronary artery bypass graft Internal mammary artery |
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10 p. |
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2010 |
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2010 |
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2019-08-29T12:01:09Z |
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2019-08-29T12:01:09Z |
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10.1016/j.ijcard.2008.09.005 |
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1874-1754 0167-5273 |
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https://repositorio.udes.edu.co/handle/001/3677 |
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10.1016/j.ijcard.2008.09.005 1874-1754 0167-5273 |
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https://repositorio.udes.edu.co/handle/001/3677 |
| dc.language.iso.spa.fl_str_mv |
eng |
| language |
eng |
| dc.relation.ispartof.eng.fl_str_mv |
International Journal of Cardiology |
| dc.relation.ispartofseries.eng.fl_str_mv |
International Journal of Cardiology;Vol.139 (1), pp. 32-41. 2010 |
| dc.rights.spa.fl_str_mv |
Derechos Reservados - International Journal of Cardiology, 2010 |
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Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0) |
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https://creativecommons.org/licenses/by-nc/4.0/ |
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Derechos Reservados - International Journal of Cardiology, 2010 Atribución-NoComercial 4.0 Internacional (CC BY-NC 4.0) https://creativecommons.org/licenses/by-nc/4.0/ http://purl.org/coar/access_right/c_abf2 |
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openAccess |
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application/pdf |
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https://www.sciencedirect.com/science/article/pii/S0167527308010127?via%3Dihub |
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Rueda Clausen, Christian F.bb29e148-b8c5-43f2-9fc0-4eeebb36706b-1Lahera, Vicente06613d10-690d-4af8-8766-1d1474e0d045-1Calderón, Jaimecddf2376-22ef-4d39-aa39-1c2b8690b4e8-1Bolivar, Isabel Cristina6200e8cc-7a64-4c86-ade1-1193c24f2c19-1Castillo, Victor R.30d3cfed-8088-4e39-b7ae-cb55b5b6ff25-1Gutiérrez, Melquisedecd97a9dfe-6e71-49b9-b885-c2924309141c-1Carreño, Marisol9f700f32-427f-4914-a58a-7104fa077ba4-1Oubiña, Maria del Pilar07b4168b-0104-40d3-96f5-efdd00a1ea2f-1Cachofeiro, Victoria1bcd3a40-1c0e-48d3-b630-66ff4e981d6f-1Lopez-Jaramillo, Patricio9a71267b-dcb0-4d31-b37d-2d30be58d4d2-12019-08-29T12:01:09Z2019-08-29T12:01:09Z201010 p.Background: Because of the strong association between abdominal obesity (AO) and other cardiovascular risk factors, it has been difficult to determine which changes in vascular function are directly related to this condition. Our objective was to evaluate the changes in ex-vivo vascular reactivity, circulating levels of adipokines and inflammatory markers associated with the presence of AO in subjects who underwent coronary artery bypass graft (CABG) controlling by the presence of other cardiovascular risk factors. Methods: Subjects scheduled for a CABG with (n=17) and without (n=17) AO (defined as a waist circumference ≥90 cm for male or ≥80 cm for female) whom were matched by several cardiovascular risk factors, were included in the study. Lipid profile and plasma levels of glucose, insulin, leptin, adiponectin and inflammatory markers were measured. Internal mammary artery segments were used for ex-vivo vascular reactivity experiments and morphometry. Results: Leptin concentrations were higher and adiponectin concentrations were lower in subjects with AO. No differences were observed in other biochemical or clinical parameters between the groups. No correlation between waist circumference, HOMA index and inflammatory markers were observed. Endothelium-dependent relaxation to acetylcholine was lower, and contractile responses to angiotensin-II were higher in subjects with AO. These changes were not related to differences in vascular morphometry. Conclusion: In subjects with severe coronary disease, the presence of AO was associated with leptin/adiponectin imbalance, decreased endothelium-dependent relaxation and an enhanced response to angiotensin-II. These changes occurred independently of other cardiovascular risk factors including insulin resistance and levels of inflammatory markers.application/pdf10.1016/j.ijcard.2008.09.0051874-17540167-5273https://repositorio.udes.edu.co/handle/001/3677engInternational Journal of CardiologyInternational Journal of Cardiology;Vol.139 (1), pp. 32-41. 2010Derechos Reservados - International Journal of Cardiology, 2010info:eu-repo/semantics/openAccessAtribución-NoComercial 4.0 Internacional (CC BY-NC 4.0)https://creativecommons.org/licenses/by-nc/4.0/http://purl.org/coar/access_right/c_abf2https://www.sciencedirect.com/science/article/pii/S0167527308010127?via%3DihubAbdominal obesityLeptinAdiponectinVascular reactivityInflammationCoronary artery bypass graftInternal mammary arteryThe presence of abdominal obesity is associated with changes in vascular function independently of other cardiovascular risk factorsArtículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Textinfo:eu-repo/semantics/articlehttp://purl.org/redcol/resource_type/ARTinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85PublicationORIGINALThe presence of abdominal obesity is associated with changes in vascular function independently of other cardiovascular risk factors.pdfThe presence of abdominal obesity is associated with changes in vascular function independently of other cardiovascular risk factors.pdfapplication/pdf253449https://repositorio.udes.edu.co/bitstreams/cc6fd280-ed6b-423a-a914-314016b6fbe7/downloadbd4386abd2a0d1fd60e575e0162d2e3eMD54LICENSElicense.txtlicense.txttext/plain; charset=utf-859https://repositorio.udes.edu.co/bitstreams/988f60b2-8c4f-472e-918d-d41437e6e9dd/download38d94cf55aa1bf2dac1a736ac45c881cMD52THUMBNAILThe presence of abdominal obesity is associated with changes in vascular function independently of other cardiovascular risk factors..PNG.jpgThe presence of abdominal obesity is associated with changes in vascular function independently of other cardiovascular risk factors..PNG.jpgGenerated Thumbnailimage/jpeg1389https://repositorio.udes.edu.co/bitstreams/05f8f9ae-4181-4298-88f0-af200711fa7a/download3958583f62db2cd4f8a5c357bd6538a2MD53The presence of abdominal obesity is associated with changes in vascular function independently of other cardiovascular risk factors.pdf.jpgThe presence of abdominal obesity is associated with changes in vascular function independently of other cardiovascular risk factors.pdf.jpgGenerated Thumbnailimage/jpeg1434https://repositorio.udes.edu.co/bitstreams/59b8b448-1b6a-4e4f-b2cf-d1efd3563fc3/downloadc584f30faf7bb70f2557634b274b0e10MD56TEXTThe presence of abdominal obesity is associated with changes in vascular function independently of other cardiovascular risk factors.pdf.txtThe presence of abdominal obesity is associated with changes in vascular function independently of other cardiovascular risk factors.pdf.txtExtracted texttext/plain2https://repositorio.udes.edu.co/bitstreams/1c87c833-ce01-469f-bb07-d62a536d9013/downloadd784fa8b6d98d27699781bd9a7cf19f0MD55001/3677oai:repositorio.udes.edu.co:001/36772023-10-10 08:47:28.542https://creativecommons.org/licenses/by-nc/4.0/Derechos Reservados - International Journal of Cardiology, 2010https://repositorio.udes.edu.coRepositorio Universidad de Santandersoporte@metabiblioteca.comTGljZW5jaWEgZGUgUHVibGljYWNpw7NuIFVERVMKRGlyZWN0cmljZXMgZGUgVVNPIHkgQUNDRVNPCgo= |