Análisis de ADN mitocondrial en restos óseos humanos prehispánicos: Filiales intra e inter poblacionales en Colombia

The genetic analysis of 33 ancient Native American samples from three locations in Colombia revealed high genetic diversity and the presence of founding haplogroups for four American populations. The study identified distinct haplotypes associated with different regions and populations. Haplogroup A...

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Autores:
Uricoechea Patiño, Daniel Alfredo
Tipo de recurso:
Doctoral thesis
Fecha de publicación:
2024
Institución:
Universidad de la Sabana
Repositorio:
Repositorio Universidad de la Sabana
Idioma:
spa
OAI Identifier:
oai:intellectum.unisabana.edu.co:10818/62990
Acceso en línea:
https://hdl.handle.net/10818/62990
Palabra clave:
Análisis genético
Diversidad genética
ADN mitocondrial
Restos humanos (Arqueología)
Rights
openAccess
License
Attribution-NonCommercial-NoDerivatives 4.0 Internacional
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dc.title.es_CO.fl_str_mv Análisis de ADN mitocondrial en restos óseos humanos prehispánicos: Filiales intra e inter poblacionales en Colombia
title Análisis de ADN mitocondrial en restos óseos humanos prehispánicos: Filiales intra e inter poblacionales en Colombia
spellingShingle Análisis de ADN mitocondrial en restos óseos humanos prehispánicos: Filiales intra e inter poblacionales en Colombia
Análisis genético
Diversidad genética
ADN mitocondrial
Restos humanos (Arqueología)
title_short Análisis de ADN mitocondrial en restos óseos humanos prehispánicos: Filiales intra e inter poblacionales en Colombia
title_full Análisis de ADN mitocondrial en restos óseos humanos prehispánicos: Filiales intra e inter poblacionales en Colombia
title_fullStr Análisis de ADN mitocondrial en restos óseos humanos prehispánicos: Filiales intra e inter poblacionales en Colombia
title_full_unstemmed Análisis de ADN mitocondrial en restos óseos humanos prehispánicos: Filiales intra e inter poblacionales en Colombia
title_sort Análisis de ADN mitocondrial en restos óseos humanos prehispánicos: Filiales intra e inter poblacionales en Colombia
dc.creator.fl_str_mv Uricoechea Patiño, Daniel Alfredo
dc.contributor.advisor.none.fl_str_mv Briceño Balcázar, Ignacio
dc.contributor.author.none.fl_str_mv Uricoechea Patiño, Daniel Alfredo
dc.subject.other.none.fl_str_mv Análisis genético
Diversidad genética
ADN mitocondrial
Restos humanos (Arqueología)
topic Análisis genético
Diversidad genética
ADN mitocondrial
Restos humanos (Arqueología)
description The genetic analysis of 33 ancient Native American samples from three locations in Colombia revealed high genetic diversity and the presence of founding haplogroups for four American populations. The study identified distinct haplotypes associated with different regions and populations. Haplogroup A5 included exclusive haplotypes found in current Central American populations, while haplogroup A2ah consisted of haplotypes from Bolivia, and haplogroup A2i contained haplotypes from the central United States. Additionally, haplogroups A2ad2 and A2af1b1 were identified, with the latter encompassing haplotypes from scattered Native American populations across Central America. Within haplogroup B, subhaplogroups B2 and B2a were linked to Native American communities along the northwest coast of the United States and Canada, while subhaplogroup B2g1 was associated with present-day inhabitants of San Diego and Mexico. The B4 subhaplogroup exhibited three distinct haplotypes: B4j, which was unique and not found elsewhere in the world; B4a1c3, which showed connections to East Asia, Central, and South America; and B4c1a1a, previously reported in East Asia.
publishDate 2024
dc.date.accessioned.none.fl_str_mv 2024-11-28T14:38:49Z
dc.date.available.none.fl_str_mv 2024-11-28T14:38:49Z
dc.date.issued.none.fl_str_mv 2024-10-24
dc.type.none.fl_str_mv Tesis/Trabajo de grado - Doctorado
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dc.language.iso.es_CO.fl_str_mv spa
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dc.publisher.es_CO.fl_str_mv Universidad de La Sabana
dc.publisher.program.none.fl_str_mv Doctorado en Biociencias
dc.publisher.faculty.none.fl_str_mv Facultad de Ingeniería
institution Universidad de la Sabana
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spelling Briceño Balcázar, IgnacioUricoechea Patiño, Daniel Alfredo2024-11-28T14:38:49Z2024-11-28T14:38:49Z2024-10-24https://hdl.handle.net/10818/62990The genetic analysis of 33 ancient Native American samples from three locations in Colombia revealed high genetic diversity and the presence of founding haplogroups for four American populations. The study identified distinct haplotypes associated with different regions and populations. Haplogroup A5 included exclusive haplotypes found in current Central American populations, while haplogroup A2ah consisted of haplotypes from Bolivia, and haplogroup A2i contained haplotypes from the central United States. Additionally, haplogroups A2ad2 and A2af1b1 were identified, with the latter encompassing haplotypes from scattered Native American populations across Central America. Within haplogroup B, subhaplogroups B2 and B2a were linked to Native American communities along the northwest coast of the United States and Canada, while subhaplogroup B2g1 was associated with present-day inhabitants of San Diego and Mexico. The B4 subhaplogroup exhibited three distinct haplotypes: B4j, which was unique and not found elsewhere in the world; B4a1c3, which showed connections to East Asia, Central, and South America; and B4c1a1a, previously reported in East Asia.El análisis genético de 33 muestras de nativos americanos antiguos de tres localidades en Colombia reveló una alta diversidad genética y la presencia de haplogrupos fundadores en cuatro poblaciones americanas. El estudio identificó haplotipos distintos asociados con diferentes regiones y poblaciones. El haplogrupo A5 incluía haplotipos exclusivos presentes en las poblaciones actuales de América Central, mientras que el haplogrupo A2ah consistía en haplotipos de Bolivia, y el haplogrupo A2i contenía haplotipos del centro de Estados Unidos. Además, se identificaron los haplogrupos A2ad2 y A2af1b1, siendo este último el que englobaba haplotipos de poblaciones nativas americanas dispersas por América Central. Dentro del haplogrupo B, los subhaplogrupos B2 y B2a se asociaron con comunidades nativas americanas a lo largo de la costa noroeste de Estados Unidos y Canadá, mientras que el subhaplogrupo B2g1 se relacionó con los habitantes actuales de San Diego y México. El subhaplogrupo B4 presentó tres haplotipos distintos: B4j, que era único y no se encontraba en ninguna otra parte del mundo; B4a1c3, que mostraba conexiones con Asia oriental, América Central y del Sur; y B4c1a1a, que se ha reportado previamente en Asia oriental.Doctor en BiocienciasDoctorado114 páginasapplication/pdfspaUniversidad de La SabanaDoctorado en BiocienciasFacultad de IngenieríaAttribution-NonCommercial-NoDerivatives 4.0 InternacionalAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/http://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Análisis genéticoDiversidad genéticaADN mitocondrialRestos humanos (Arqueología)Análisis de ADN mitocondrial en restos óseos humanos prehispánicos: Filiales intra e inter poblacionales en ColombiaTesis/Trabajo de grado - Doctoradohttp://purl.org/coar/resource_type/c_db06http://purl.org/coar/version/c_970fb48d4fbd8a85info:eu-repo/semantics/doctoralThesishttp://purl.org/redcol/resource_type/TDPublicationORIGINALTesis Daniel Uricoechea biblioteca-3-114.pdfTesis Daniel Uricoechea biblioteca-3-114.pdfVer documento en PDFapplication/pdf1145254https://intellectum.unisabana.edu.co/bitstreams/b241718b-7286-4b7a-9f78-4ae3d32bf002/download95938993c219329cbb67d327adca7e8cMD52trueAnonymousREADLICENSETesis Daniel Uricoechea biblioteca-1-2.pdfTesis Daniel Uricoechea biblioteca-1-2.pdfCartaapplication/pdf814041https://intellectum.unisabana.edu.co/bitstreams/9c9183ab-edd6-4de4-88c8-b9c730af095d/download7bc218e16dbb2686ab023957ce0a1508MD51falseAdministratorREADTEXTTesis Daniel Uricoechea biblioteca-3-114.pdf.txtTesis Daniel Uricoechea biblioteca-3-114.pdf.txtExtracted texttext/plain191597https://intellectum.unisabana.edu.co/bitstreams/0b27fd9f-6f9f-430a-9870-f6705d45719b/download16a0db60f3546869d3cc5f83b9f4b7b8MD53falseAnonymousREADTHUMBNAILTesis Daniel Uricoechea biblioteca-3-114.pdf.jpgTesis Daniel Uricoechea biblioteca-3-114.pdf.jpgGenerated Thumbnailimage/jpeg5920https://intellectum.unisabana.edu.co/bitstreams/2f34cbdc-a761-4ce8-bc9c-cc4198e7769c/download8afb5312632d3cf300d27b9d1ee153b9MD54falseAnonymousREAD10818/62990oai:intellectum.unisabana.edu.co:10818/629902026-02-11 11:53:13.127http://creativecommons.org/licenses/by-nc-nd/4.0/Attribution-NonCommercial-NoDerivatives 4.0 Internacionalopen.accesshttps://intellectum.unisabana.edu.coIntellectum Repositorio Universidad de La Sabanacontactointellectum@unisabana.edu.co

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