Frequency of hemorrhagic complications in plasmapheresis without extracorporeal circuit anticoagulation, in children

5 páginas

Autores:: Fernández Sarmiento, Jaime
Varela, María A.
Pinzón Flórez, Carlos Eduardo

Tipo de recurso:

Fecha de publicación:: 2016

Institución:: Universidad de la Sabana

Repositorio:: Repositorio Universidad de la Sabana

Idioma:: eng

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spelling	Fernández Sarmiento, JaimeVarela, María A.Pinzón Flórez, Carlos Eduardo8/26/2019 9:262019-08-26T14:26:50Z2016https://www.sciencedirect.com/science/article/pii/S1473050216300210?via%3Dihubhttp://hdl.handle.net/10818/3683810.1016/j.transci.2016.05.0025 páginasBackground The current practice of plasmapheresis at most centers employs anticoagulation of the extracorporeal circuit, which has been associated with complications. There are few studies evaluating the efficacy and safety of using plasmapheresis without any anticoagulation. We report our experience using this strategy in children (1 month to 18 years old) over a period of 5 years. Results Two hundred forty-three plasmapheresis sessions without anticoagulation of the extracorporeal circuit, in 27 pediatric patients, were analyzed. Of these, 81.4% were female and the predominant age range was 12–18 years (70.3%). One hundred percent of the patients had PRISM III scale low mortality risk, and the main indication of therapy was acute rejection after renal transplantation (25.9%), followed by recurrence of focal segmental sclerosis in the transplanted kidney (17.2%). Filtration lasted more than 3 hours in 86.8% of cases, with bleeding complications in 2.9% of patients requiring early termination due to associated complications in 3.2% of cases. Other complications were paresthesias (0.41%), vomiting (5%), hypertension during (67.4%) and after therapy (64.6%), and hyperchloremia (46.5%). Conclusions In our experience, plasmapheresis without circuit anticoagulation in children is safe and effective, with a low frequency of bleeding and hydroelectrolytic complications, allowing the achievement of therapeutic goals without altering therapy duration and efficiency. Prospective studies are needed to corroborate these findings.application/pdfengTransfusion and Apheresis ScienceTransfusion and Apheresis Science Volume 55, Issue 1, August 2016, Pages 136-140Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/http://purl.org/coar/access_right/c_abf2Universidad de La SabanaIntellectum Repositorio Universidad de La SabanaPlasmapheresisApheresisTherapeutic plasma exchangeAnticoagulationFrequency of hemorrhagic complications in plasmapheresis without extracorporeal circuit anticoagulation, in childrenarticlepublishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8805https://intellectum.unisabana.edu.co/bitstream/10818/36838/2/license_rdf4460e5956bc1d1639be9ae6146a50347MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-8498https://intellectum.unisabana.edu.co/bitstream/10818/36838/3/license.txtf52a2cfd4df262e08e9b300d62c85cabMD5310818/36838oai:intellectum.unisabana.edu.co:10818/368382022-05-10 05:18:44.215Intellectum Universidad de la Sabanacontactointellectum@unisabana.edu.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
dc.title.es_CO.fl_str_mv	Frequency of hemorrhagic complications in plasmapheresis without extracorporeal circuit anticoagulation, in children
title	Frequency of hemorrhagic complications in plasmapheresis without extracorporeal circuit anticoagulation, in children
spellingShingle	Frequency of hemorrhagic complications in plasmapheresis without extracorporeal circuit anticoagulation, in children Plasmapheresis Apheresis Therapeutic plasma exchange Anticoagulation
title_short	Frequency of hemorrhagic complications in plasmapheresis without extracorporeal circuit anticoagulation, in children
title_full	Frequency of hemorrhagic complications in plasmapheresis without extracorporeal circuit anticoagulation, in children
title_fullStr	Frequency of hemorrhagic complications in plasmapheresis without extracorporeal circuit anticoagulation, in children
title_full_unstemmed	Frequency of hemorrhagic complications in plasmapheresis without extracorporeal circuit anticoagulation, in children
title_sort	Frequency of hemorrhagic complications in plasmapheresis without extracorporeal circuit anticoagulation, in children
dc.creator.fl_str_mv	Fernández Sarmiento, Jaime Varela, María A. Pinzón Flórez, Carlos Eduardo
dc.contributor.author.none.fl_str_mv	Fernández Sarmiento, Jaime Varela, María A. Pinzón Flórez, Carlos Eduardo
dc.subject.es_CO.fl_str_mv	Plasmapheresis Apheresis Therapeutic plasma exchange Anticoagulation
topic	Plasmapheresis Apheresis Therapeutic plasma exchange Anticoagulation
description	5 páginas
publishDate	2016
dc.date.issued.none.fl_str_mv	2016
dc.date.available.none.fl_str_mv	2019-08-26T14:26:50Z
dc.date.accessioned.none.fl_str_mv	8/26/2019 9:26
dc.type.en.fl_str_mv	article
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dc.identifier.other.none.fl_str_mv	https://www.sciencedirect.com/science/article/pii/S1473050216300210?via%3Dihub
dc.identifier.uri.none.fl_str_mv	http://hdl.handle.net/10818/36838
dc.identifier.doi.none.fl_str_mv	10.1016/j.transci.2016.05.002
url	https://www.sciencedirect.com/science/article/pii/S1473050216300210?via%3Dihub http://hdl.handle.net/10818/36838
identifier_str_mv	10.1016/j.transci.2016.05.002
dc.language.iso.es_CO.fl_str_mv	eng
language	eng
dc.relation.ispartofseries.none.fl_str_mv	Transfusion and Apheresis Science Volume 55, Issue 1, August 2016, Pages 136-140
dc.rights.*.fl_str_mv	Attribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.coar.fl_str_mv	http://purl.org/coar/access_right/c_abf2
dc.rights.uri.*.fl_str_mv	http://creativecommons.org/licenses/by-nc-nd/4.0/
rights_invalid_str_mv	Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ http://purl.org/coar/access_right/c_abf2
dc.format.es_CO.fl_str_mv	application/pdf
dc.publisher.es_CO.fl_str_mv	Transfusion and Apheresis Science
dc.source.es_CO.fl_str_mv	Universidad de La Sabana Intellectum Repositorio Universidad de La Sabana
institution	Universidad de la Sabana
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Frequency of hemorrhagic complications in plasmapheresis without extracorporeal circuit anticoagulation, in children

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