Uso de Levosimendán en el postoperatorio de cirugía cardiaca.

48 Páginas.

Autores:: Hernández Parra, Ángela

Tipo de recurso:

Fecha de publicación:: 2010

Institución:: Universidad de la Sabana

Repositorio:: Repositorio Universidad de la Sabana

Idioma:: spa

id	REPOUSABA2_ea1db72cf74745b21d562ac26d11fb9f
oai_identifier_str	oai:intellectum.unisabana.edu.co:10818/7516
network_acronym_str	REPOUSABA2
network_name_str	Repositorio Universidad de la Sabana
repository_id_str
dc.title.es_CO.fl_str_mv	Uso de Levosimendán en el postoperatorio de cirugía cardiaca.
title	Uso de Levosimendán en el postoperatorio de cirugía cardiaca.
spellingShingle	Uso de Levosimendán en el postoperatorio de cirugía cardiaca. Corazón Medicamentos
title_short	Uso de Levosimendán en el postoperatorio de cirugía cardiaca.
title_full	Uso de Levosimendán en el postoperatorio de cirugía cardiaca.
title_fullStr	Uso de Levosimendán en el postoperatorio de cirugía cardiaca.
title_full_unstemmed	Uso de Levosimendán en el postoperatorio de cirugía cardiaca.
title_sort	Uso de Levosimendán en el postoperatorio de cirugía cardiaca.
dc.creator.fl_str_mv	Hernández Parra, Ángela
dc.contributor.advisor.none.fl_str_mv	Buitrago Bernal, Ricardo Antonio
dc.contributor.author.none.fl_str_mv	Hernández Parra, Ángela
dc.subject.es_CO.fl_str_mv	Corazón Medicamentos
topic	Corazón Medicamentos
description	48 Páginas.
publishDate	2010
dc.date.created.none.fl_str_mv	2010
dc.date.issued.none.fl_str_mv	2010
dc.date.accessioned.none.fl_str_mv	2013-05-23T20:13:53Z
dc.date.available.none.fl_str_mv	2013-05-23T20:13:53Z
dc.type.none.fl_str_mv	bachelorThesis
dc.type.coarversion.fl_str_mv	http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv	http://purl.org/coar/resource_type/c_7a1f
dc.type.local.none.fl_str_mv	Tesis de especialización
dc.type.hasVersion.none.fl_str_mv	publishedVersion
dc.identifier.citation.none.fl_str_mv	. Gillies M., Bellomo R, et al. Bench-to-bedside review: Inotropic drug therapy after adult cardiac surgery – a systematic literature review. Crit Care. 2005 Jun;9(3):266- 79 Papp Z., Csapó K., et al. Pharmacological mechanisms contributing to the clinical efficacy of levosimendan. Cardiovasc Drug Rev. 2005 Spring; 23(1):71-98. Nieminen MS, Böhm M, et al. Executive summary of the guidelines on the diagnosis and treatment of acute heart failure: the Task Force on Acute Herat Failure of the Eur Heart J. 2008; 29: 2388 - 442 Raja S., Rayen B. Levosimendan in Cardiac Surgery: Current Best: Available Evidence. Ann Thorac Surg. 2006 Apr; 81(4):1536-46. Salmenperä M, Eriksson H., et al. Levosimendan in perioperative and critical care patients. Curr Opin Anaesthesiol. 2009 Aug; 22(4):496-501. Opie L. Braunwald Heart Disease Cardiovascular. 8a Edición, 2007. Capítulo 21: Mecanismos de la contracción y la relajación cardiaca Cardiovascular Physiology. Lange. 5a Edición, 2005. Capítulo 2: Características de las células musculares cardiacas Butler J, Giamouzis G, et al. A struggle to SURVIVE: to abandon or not to abandon levosimendan? Cardiovasc Drugs Ther 2007 Oct;21(5):401-2. Archan S, Toller W, et al. Levosimendan: current status and future prospects. Curr Opin Anaesthesiol 2008 Feb;21(1):78-84. Delaney A, Bradford C, et al. Levosimendan for the treatment of acute severe heart failure: A meta-analysis of randomised controlled trials. Int J Cardiol. 2010 Feb 4;138(3):281-9 Rehberg S, Ertmer C, et al. Role of Levosimendan in intensive care treatment of myocardial insufficiency. Anaesthesist 2007 Jan;56(1):30-43. Toller WG, Stranz C. Levosimendan, a new inotropic and vasodilator agent. Anesthesiology 2006 Mar;104(3):556-69. Yildiz O. Vasodilating mechanisms of levosimendan: involvement of K+ channels. J Pharmacol Sci 2007 May;104(1):1-5. Soedeing P. Inoprotection: the perioperative role of levosimendan. Anesth Intensive Care. 2007 Dec; 35(6):845-62. Álvarez J., Taboada M., et al. Efectos hemodinámicos del levosimendan en el postoperatorio de pacientes sometidos a cirugía cardiaca. Rev Esp Anestesiol Reanim. 2005; 52: 389-94 Duygu H, Ozerkan F, et al. Effect of levosimendan on right ventricular systolic and diastolic functions in patients with ischaemic heart failure. Int J Clin Pract 2008 Feb;62(2):228-33. Delle Karth G, Buberl A, et al. Hemodynamic effects of a continuous infusion of levosimendan in critically ill patients with cardiogenic shock requiring catecholamines. Acta Anaesthesiol Scand 2003 Nov;47(10):1251-6. Russ MA, Prondzinsky R, et al. Hemodynamic improvement following levosimendan treatment in patients with acute myocardial infarction and cardiogenic shock. Crit Care Med 2007 Dec;35(12):2732-9. Pinto, B., Rehberg S., et al. Role of levosimendan in sepsis and septic shock. Curr Opin Anesthesiol 2008 Apr;21(2):168-77. Tritapepe L, De Santis V, et al. Preconditioning effects of levosimendan in coronary artery bypass grafting--a pilot study. Br J Anaesth 2006 Jun;96(6):694-700 De Hert SG, Lorsomradee S, et al. The effects of levosimendan in cardiac surgery patients with poor left ventricular function. Anesth Analg 2007 Apr;104(4):766-73. Tasouli A, Papadopoulos K, et al. Efficacy and safety of perioperative infusion of levosimendan in patients with compromised cardiac function undergoing open-heart surgery: importance of early use. Eur J Cardiothorac Surg 2007 Oct;32(4):629-33. Levin R., Degrange M. The Calcium Sensitizer Levosimendan Gives Superior Results to Dobutamine in Postoperative Low Cardiac Output Syndrome. Rev Esp Cardiol 2008 May;61(5):471-9. Kerbaul F, Rondelet B, et al. Effects of levosimendan versus dobutamine on pressure load-induced right ventricular failure. Crit Care Med 2006 Nov;34(11):2814-9. Follath F, Cleland JG., et al. Efficacy and safety of intravenous levosimendan compared with dobutamine in severe low-output heart f Lancet 2002, Jul; 360(9328):196-202. Moiseyev VS, Poder P., et al. Safety and efficacy of a novel calcium sensitizer, levosimendan, in patients with left ventricular failure due to an acute myocardial infarction. A randomized, placebo-controlled, double-blind study (RUSSLAN). Eur Heart J 2002 Sep;23(18):1422-32. Johansson S, et al. Effect of levosimendan treatment on length of hospital and intensive care stay in the REVIVE I study. Crit Care 2004; 8 Sup 1: 88. Landoni G. et al. Reducing mortality in cardiac surgery with Levosimendan: A Meta-analysis of Randomized Controlled Trials. J Cardiothorac Vasc Anesth. 2010 Feb;24(1):51-7. Aksun N, Karahan M. et al. Timing of levosimendan in cardiac surgery. Anadolu Kardiyol Derg. 2009 Jun;9(3):223-30. De Santis V., Vitale D. et al. Levosimendan and cardiac surgery. Cardiothorac Vasc Anesth. 2010 Feb;24(1):210. Nieminen MS, Pollesello P, et al. Effects of levosimendan on the energy balance: preclinical and clinical evidence. J Cardiovasc Pharmacol. 2009 Apr; 53(4):302-10.
dc.identifier.uri.none.fl_str_mv	http://hdl.handle.net/10818/7516
dc.identifier.local.none.fl_str_mv	129265 TE01309
identifier_str_mv	. Gillies M., Bellomo R, et al. Bench-to-bedside review: Inotropic drug therapy after adult cardiac surgery – a systematic literature review. Crit Care. 2005 Jun;9(3):266- 79 Papp Z., Csapó K., et al. Pharmacological mechanisms contributing to the clinical efficacy of levosimendan. Cardiovasc Drug Rev. 2005 Spring; 23(1):71-98. Nieminen MS, Böhm M, et al. Executive summary of the guidelines on the diagnosis and treatment of acute heart failure: the Task Force on Acute Herat Failure of the Eur Heart J. 2008; 29: 2388 - 442 Raja S., Rayen B. Levosimendan in Cardiac Surgery: Current Best: Available Evidence. Ann Thorac Surg. 2006 Apr; 81(4):1536-46. Salmenperä M, Eriksson H., et al. Levosimendan in perioperative and critical care patients. Curr Opin Anaesthesiol. 2009 Aug; 22(4):496-501. Opie L. Braunwald Heart Disease Cardiovascular. 8a Edición, 2007. Capítulo 21: Mecanismos de la contracción y la relajación cardiaca Cardiovascular Physiology. Lange. 5a Edición, 2005. Capítulo 2: Características de las células musculares cardiacas Butler J, Giamouzis G, et al. A struggle to SURVIVE: to abandon or not to abandon levosimendan? Cardiovasc Drugs Ther 2007 Oct;21(5):401-2. Archan S, Toller W, et al. Levosimendan: current status and future prospects. Curr Opin Anaesthesiol 2008 Feb;21(1):78-84. Delaney A, Bradford C, et al. Levosimendan for the treatment of acute severe heart failure: A meta-analysis of randomised controlled trials. Int J Cardiol. 2010 Feb 4;138(3):281-9 Rehberg S, Ertmer C, et al. Role of Levosimendan in intensive care treatment of myocardial insufficiency. Anaesthesist 2007 Jan;56(1):30-43. Toller WG, Stranz C. Levosimendan, a new inotropic and vasodilator agent. Anesthesiology 2006 Mar;104(3):556-69. Yildiz O. Vasodilating mechanisms of levosimendan: involvement of K+ channels. J Pharmacol Sci 2007 May;104(1):1-5. Soedeing P. Inoprotection: the perioperative role of levosimendan. Anesth Intensive Care. 2007 Dec; 35(6):845-62. Álvarez J., Taboada M., et al. Efectos hemodinámicos del levosimendan en el postoperatorio de pacientes sometidos a cirugía cardiaca. Rev Esp Anestesiol Reanim. 2005; 52: 389-94 Duygu H, Ozerkan F, et al. Effect of levosimendan on right ventricular systolic and diastolic functions in patients with ischaemic heart failure. Int J Clin Pract 2008 Feb;62(2):228-33. Delle Karth G, Buberl A, et al. Hemodynamic effects of a continuous infusion of levosimendan in critically ill patients with cardiogenic shock requiring catecholamines. Acta Anaesthesiol Scand 2003 Nov;47(10):1251-6. Russ MA, Prondzinsky R, et al. Hemodynamic improvement following levosimendan treatment in patients with acute myocardial infarction and cardiogenic shock. Crit Care Med 2007 Dec;35(12):2732-9. Pinto, B., Rehberg S., et al. Role of levosimendan in sepsis and septic shock. Curr Opin Anesthesiol 2008 Apr;21(2):168-77. Tritapepe L, De Santis V, et al. Preconditioning effects of levosimendan in coronary artery bypass grafting--a pilot study. Br J Anaesth 2006 Jun;96(6):694-700 De Hert SG, Lorsomradee S, et al. The effects of levosimendan in cardiac surgery patients with poor left ventricular function. Anesth Analg 2007 Apr;104(4):766-73. Tasouli A, Papadopoulos K, et al. Efficacy and safety of perioperative infusion of levosimendan in patients with compromised cardiac function undergoing open-heart surgery: importance of early use. Eur J Cardiothorac Surg 2007 Oct;32(4):629-33. Levin R., Degrange M. The Calcium Sensitizer Levosimendan Gives Superior Results to Dobutamine in Postoperative Low Cardiac Output Syndrome. Rev Esp Cardiol 2008 May;61(5):471-9. Kerbaul F, Rondelet B, et al. Effects of levosimendan versus dobutamine on pressure load-induced right ventricular failure. Crit Care Med 2006 Nov;34(11):2814-9. Follath F, Cleland JG., et al. Efficacy and safety of intravenous levosimendan compared with dobutamine in severe low-output heart f Lancet 2002, Jul; 360(9328):196-202. Moiseyev VS, Poder P., et al. Safety and efficacy of a novel calcium sensitizer, levosimendan, in patients with left ventricular failure due to an acute myocardial infarction. A randomized, placebo-controlled, double-blind study (RUSSLAN). Eur Heart J 2002 Sep;23(18):1422-32. Johansson S, et al. Effect of levosimendan treatment on length of hospital and intensive care stay in the REVIVE I study. Crit Care 2004; 8 Sup 1: 88. Landoni G. et al. Reducing mortality in cardiac surgery with Levosimendan: A Meta-analysis of Randomized Controlled Trials. J Cardiothorac Vasc Anesth. 2010 Feb;24(1):51-7. Aksun N, Karahan M. et al. Timing of levosimendan in cardiac surgery. Anadolu Kardiyol Derg. 2009 Jun;9(3):223-30. De Santis V., Vitale D. et al. Levosimendan and cardiac surgery. Cardiothorac Vasc Anesth. 2010 Feb;24(1):210. Nieminen MS, Pollesello P, et al. Effects of levosimendan on the energy balance: preclinical and clinical evidence. J Cardiovasc Pharmacol. 2009 Apr; 53(4):302-10. 129265 TE01309
url	http://hdl.handle.net/10818/7516
dc.language.iso.es_CO.fl_str_mv	spa
language	spa
dc.rights.coar.fl_str_mv	http://purl.org/coar/access_right/c_abf2
rights_invalid_str_mv	http://purl.org/coar/access_right/c_abf2
dc.publisher.none.fl_str_mv	Universidad de La Sabana
dc.publisher.program.none.fl_str_mv	Especialización en Medicina Crítica y Cuidado Intensivo
dc.publisher.department.none.fl_str_mv	Facultad de Medicina
publisher.none.fl_str_mv	Universidad de La Sabana
dc.source.none.fl_str_mv	Universidad de La Sabana Intellectum Repositorio Universidad de La Sabana
institution	Universidad de la Sabana
bitstream.url.fl_str_mv	https://intellectum.unisabana.edu.co/bitstream/10818/7516/1/124028.pdf https://intellectum.unisabana.edu.co/bitstream/10818/7516/2/license.txt https://intellectum.unisabana.edu.co/bitstream/10818/7516/3/124028.pdf.txt
bitstream.checksum.fl_str_mv	931f16008fd313fb24e9ac08460d6c68 f52a2cfd4df262e08e9b300d62c85cab 06908b78dacf7ba63e94a71b693eb83c
bitstream.checksumAlgorithm.fl_str_mv	MD5 MD5 MD5
repository.name.fl_str_mv	Intellectum Universidad de la Sabana
repository.mail.fl_str_mv	contactointellectum@unisabana.edu.co
_version_	1811952234847535104
spelling	Buitrago Bernal, Ricardo AntonioHernández Parra, ÁngelaEspecialista en Medicina Crítica y Cuidado Intensivo2013-05-23T20:13:53Z2013-05-23T20:13:53Z20102010. Gillies M., Bellomo R, et al. Bench-to-bedside review: Inotropic drug therapy after adult cardiac surgery – a systematic literature review. Crit Care. 2005 Jun;9(3):266- 79Papp Z., Csapó K., et al. Pharmacological mechanisms contributing to the clinical efficacy of levosimendan. Cardiovasc Drug Rev. 2005 Spring; 23(1):71-98.Nieminen MS, Böhm M, et al. Executive summary of the guidelines on the diagnosis and treatment of acute heart failure: the Task Force on Acute Herat Failure of the Eur Heart J. 2008; 29: 2388 - 442Raja S., Rayen B. Levosimendan in Cardiac Surgery: Current Best: Available Evidence. Ann Thorac Surg. 2006 Apr; 81(4):1536-46.Salmenperä M, Eriksson H., et al. Levosimendan in perioperative and critical care patients. Curr Opin Anaesthesiol. 2009 Aug; 22(4):496-501.Opie L. Braunwald Heart Disease Cardiovascular. 8a Edición, 2007. Capítulo 21: Mecanismos de la contracción y la relajación cardiacaCardiovascular Physiology. Lange. 5a Edición, 2005. Capítulo 2: Características de las células musculares cardiacasButler J, Giamouzis G, et al. A struggle to SURVIVE: to abandon or not to abandon levosimendan? Cardiovasc Drugs Ther 2007 Oct;21(5):401-2.Archan S, Toller W, et al. Levosimendan: current status and future prospects. Curr Opin Anaesthesiol 2008 Feb;21(1):78-84.Delaney A, Bradford C, et al. Levosimendan for the treatment of acute severe heart failure: A meta-analysis of randomised controlled trials. Int J Cardiol. 2010 Feb 4;138(3):281-9Rehberg S, Ertmer C, et al. Role of Levosimendan in intensive care treatment of myocardial insufficiency. Anaesthesist 2007 Jan;56(1):30-43.Toller WG, Stranz C. Levosimendan, a new inotropic and vasodilator agent. Anesthesiology 2006 Mar;104(3):556-69.Yildiz O. Vasodilating mechanisms of levosimendan: involvement of K+ channels. J Pharmacol Sci 2007 May;104(1):1-5.Soedeing P. Inoprotection: the perioperative role of levosimendan. Anesth Intensive Care. 2007 Dec; 35(6):845-62.Álvarez J., Taboada M., et al. Efectos hemodinámicos del levosimendan en el postoperatorio de pacientes sometidos a cirugía cardiaca. Rev Esp Anestesiol Reanim. 2005; 52: 389-94Duygu H, Ozerkan F, et al. Effect of levosimendan on right ventricular systolic and diastolic functions in patients with ischaemic heart failure. Int J Clin Pract 2008 Feb;62(2):228-33.Delle Karth G, Buberl A, et al. Hemodynamic effects of a continuous infusion of levosimendan in critically ill patients with cardiogenic shock requiring catecholamines. Acta Anaesthesiol Scand 2003 Nov;47(10):1251-6.Russ MA, Prondzinsky R, et al. Hemodynamic improvement following levosimendan treatment in patients with acute myocardial infarction and cardiogenic shock. Crit Care Med 2007 Dec;35(12):2732-9.Pinto, B., Rehberg S., et al. Role of levosimendan in sepsis and septic shock. Curr Opin Anesthesiol 2008 Apr;21(2):168-77.Tritapepe L, De Santis V, et al. Preconditioning effects of levosimendan in coronary artery bypass grafting--a pilot study. Br J Anaesth 2006 Jun;96(6):694-700De Hert SG, Lorsomradee S, et al. The effects of levosimendan in cardiac surgery patients with poor left ventricular function. Anesth Analg 2007 Apr;104(4):766-73.Tasouli A, Papadopoulos K, et al. Efficacy and safety of perioperative infusion of levosimendan in patients with compromised cardiac function undergoing open-heart surgery: importance of early use. Eur J Cardiothorac Surg 2007 Oct;32(4):629-33.Levin R., Degrange M. The Calcium Sensitizer Levosimendan Gives Superior Results to Dobutamine in Postoperative Low Cardiac Output Syndrome. Rev Esp Cardiol 2008 May;61(5):471-9.Kerbaul F, Rondelet B, et al. Effects of levosimendan versus dobutamine on pressure load-induced right ventricular failure. Crit Care Med 2006 Nov;34(11):2814-9.Follath F, Cleland JG., et al. Efficacy and safety of intravenous levosimendan compared with dobutamine in severe low-output heart f Lancet 2002, Jul; 360(9328):196-202.Moiseyev VS, Poder P., et al. Safety and efficacy of a novel calcium sensitizer, levosimendan, in patients with left ventricular failure due to an acute myocardial infarction. A randomized, placebo-controlled, double-blind study (RUSSLAN). Eur Heart J 2002 Sep;23(18):1422-32.Johansson S, et al. Effect of levosimendan treatment on length of hospital and intensive care stay in the REVIVE I study. Crit Care 2004; 8 Sup 1: 88.Landoni G. et al. Reducing mortality in cardiac surgery with Levosimendan: A Meta-analysis of Randomized Controlled Trials. J Cardiothorac Vasc Anesth. 2010 Feb;24(1):51-7.Aksun N, Karahan M. et al. Timing of levosimendan in cardiac surgery. Anadolu Kardiyol Derg. 2009 Jun;9(3):223-30.De Santis V., Vitale D. et al. Levosimendan and cardiac surgery. Cardiothorac Vasc Anesth. 2010 Feb;24(1):210.Nieminen MS, Pollesello P, et al. Effects of levosimendan on the energy balance: preclinical and clinical evidence. J Cardiovasc Pharmacol. 2009 Apr; 53(4):302-10.http://hdl.handle.net/10818/7516129265TE0130948 Páginas.Levosimendán es inotrópico y vasodilatador, con mecanismo de acción diferente, utilizado en falla cardiaca. En cirugía cardiaca la literatura es limitada, sin concluir efectividad e impacto en morbimortalidad. Este trabajo muestra el comportamiento hemodinámico y de perfusión tisular de pacientes con disfunción ventricular en postoperatorio, usando Levosimendán. 78 pacientes recibieron infusión de 0.1 mcg/kg/min; se recolectaron parámetros hemodinámicos y de perfusión tisular antes, durante y al finalizar la infusión para análisis descriptivo. Se observó aumento en índice cardiaco, disminución en presión capilar pulmonar; aumento en saturación venosa de oxígeno, disminución en Da-vO2, delta de CO2, tasa de extracción y base exceso. En este grupo de pacientes se observó mejoría en perfil hemodinámico y perfusión tisular, tras la infusión.spaUniversidad de La SabanaEspecialización en Medicina Crítica y Cuidado IntensivoFacultad de MedicinaUniversidad de La SabanaIntellectum Repositorio Universidad de La SabanaCorazónMedicamentosUso de Levosimendán en el postoperatorio de cirugía cardiaca.bachelorThesisTesis de especializaciónpublishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_7a1fhttp://purl.org/coar/access_right/c_abf2ORIGINAL124028.pdf124028.pdfVer documento en PDFapplication/pdf235433https://intellectum.unisabana.edu.co/bitstream/10818/7516/1/124028.pdf931f16008fd313fb24e9ac08460d6c68MD51LICENSElicense.txtlicense.txttext/plain; charset=utf-8498https://intellectum.unisabana.edu.co/bitstream/10818/7516/2/license.txtf52a2cfd4df262e08e9b300d62c85cabMD52TEXT124028.pdf.txt124028.pdf.txtExtracted Texttext/plain70485https://intellectum.unisabana.edu.co/bitstream/10818/7516/3/124028.pdf.txt06908b78dacf7ba63e94a71b693eb83cMD5310818/7516oai:intellectum.unisabana.edu.co:10818/75162021-04-25 18:25:31.347Intellectum Universidad de la Sabanacontactointellectum@unisabana.edu.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

Uso de Levosimendán en el postoperatorio de cirugía cardiaca.

Publicaciones similares