Cutaneous PEComas Express CD10: Implications for the Classification of PEComas and the Differential Diagnosis With Metastatic Renal Cell Carcinoma

8 páginas

Autores:: Ángel, Fernández Flores
Catherine M., Nguyen
Cassarino, David Samuel

Tipo de recurso:

Fecha de publicación:: 2016

Institución:: Universidad de la Sabana

Repositorio:: Repositorio Universidad de la Sabana

Idioma:: eng

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spelling	Ángel, Fernández FloresCatherine M., NguyenCassarino, David Samuel2/11/2019 9:192019-02-11T14:19:27Z2016-090193-1091https://journals.lww.com/amjdermatopathology/Fulltext/2016/09000/Cutaneous_PEComas_Express_CD10___Implications_for.1.aspxhttp://hdl.handle.net/10818/349288 páginasCutaneous perivascular epithelioid cell tumors (PEComas) are peculiar, rare mesenchymal tumors of uncertain lineage. They show a characteristic epithelioid morphology, and they are usually composed of monomorphous clear-to-granular appearing perivascular cells. One of the main differential diagnoses with PEComas is a cutaneous metastasis from renal cell carcinoma (RCC). CD10 has been emphasized to be a crucial marker in the diagnosis of metastasis from RCC. Although visceral PEComas have been studied for CD10 expression, primary cutaneous PEComas have not. Although it could be assumed a priori that cutaneous PEComas would stain as their visceral counterpart, there is increasing evidence that cutaneous PEComas could actually be unrelated to PEComas from other organs. In this report, the author's studied three primary cutaneous PEComas, and included CD10 in our immunohistochemical studies. All three PEComas expressed the marker. They conclude that a CD10+ clear-cell dermal tumor is not necessarily equivalent to a metastasis from RCC and that additional stains should be added to rule out PEComa, even if the biopsy or the panel of antibodies is limited.application/pdfengThe American Journal of DermatopathologyAm J Dermatopathol 2016;38:645–652Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/http://purl.org/coar/access_right/c_abf2Universidad de La SabanaIntellectum Repositorio Universidad de La SabanaPEComaCD10malignant PEComaCutaneous metastatic renal cell carcinomaCutaneous PEComas Express CD10: Implications for the Classification of PEComas and the Differential Diagnosis With Metastatic Renal Cell CarcinomaarticlepublishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8805https://intellectum.unisabana.edu.co/bitstream/10818/34928/2/license_rdf4460e5956bc1d1639be9ae6146a50347MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-8498https://intellectum.unisabana.edu.co/bitstream/10818/34928/3/license.txtf52a2cfd4df262e08e9b300d62c85cabMD5310818/34928oai:intellectum.unisabana.edu.co:10818/349282022-05-10 05:17:44.314Intellectum Universidad de la Sabanacontactointellectum@unisabana.edu.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
dc.title.es_CO.fl_str_mv	Cutaneous PEComas Express CD10: Implications for the Classification of PEComas and the Differential Diagnosis With Metastatic Renal Cell Carcinoma
title	Cutaneous PEComas Express CD10: Implications for the Classification of PEComas and the Differential Diagnosis With Metastatic Renal Cell Carcinoma
spellingShingle	Cutaneous PEComas Express CD10: Implications for the Classification of PEComas and the Differential Diagnosis With Metastatic Renal Cell Carcinoma PEComa CD10 malignant PEComa Cutaneous metastatic renal cell carcinoma
title_short	Cutaneous PEComas Express CD10: Implications for the Classification of PEComas and the Differential Diagnosis With Metastatic Renal Cell Carcinoma
title_full	Cutaneous PEComas Express CD10: Implications for the Classification of PEComas and the Differential Diagnosis With Metastatic Renal Cell Carcinoma
title_fullStr	Cutaneous PEComas Express CD10: Implications for the Classification of PEComas and the Differential Diagnosis With Metastatic Renal Cell Carcinoma
title_full_unstemmed	Cutaneous PEComas Express CD10: Implications for the Classification of PEComas and the Differential Diagnosis With Metastatic Renal Cell Carcinoma
title_sort	Cutaneous PEComas Express CD10: Implications for the Classification of PEComas and the Differential Diagnosis With Metastatic Renal Cell Carcinoma
dc.creator.fl_str_mv	Ángel, Fernández Flores Catherine M., Nguyen Cassarino, David Samuel
dc.contributor.author.none.fl_str_mv	Ángel, Fernández Flores Catherine M., Nguyen Cassarino, David Samuel
dc.subject.es_CO.fl_str_mv	PEComa CD10 malignant PEComa Cutaneous metastatic renal cell carcinoma
topic	PEComa CD10 malignant PEComa Cutaneous metastatic renal cell carcinoma
description	8 páginas
publishDate	2016
dc.date.accessioned.none.fl_str_mv	2/11/2019 9:19
dc.date.issued.none.fl_str_mv	2016-09
dc.date.available.none.fl_str_mv	2019-02-11T14:19:27Z
dc.type.en.fl_str_mv	article
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dc.identifier.issn.none.fl_str_mv	0193-1091
dc.identifier.other.none.fl_str_mv	https://journals.lww.com/amjdermatopathology/Fulltext/2016/09000/Cutaneous_PEComas_Express_CD10___Implications_for.1.aspx
dc.identifier.uri.none.fl_str_mv	http://hdl.handle.net/10818/34928
identifier_str_mv	0193-1091
url	https://journals.lww.com/amjdermatopathology/Fulltext/2016/09000/Cutaneous_PEComas_Express_CD10___Implications_for.1.aspx http://hdl.handle.net/10818/34928
dc.language.iso.es_CO.fl_str_mv	eng
language	eng
dc.relation.ispartofseries.none.fl_str_mv	Am J Dermatopathol 2016;38:645–652
dc.rights.*.fl_str_mv	Attribution-NonCommercial-NoDerivatives 4.0 International
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dc.format.es_CO.fl_str_mv	application/pdf
dc.publisher.es_CO.fl_str_mv	The American Journal of Dermatopathology
dc.source.es_CO.fl_str_mv	Universidad de La Sabana Intellectum Repositorio Universidad de La Sabana
institution	Universidad de la Sabana
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Cutaneous PEComas Express CD10: Implications for the Classification of PEComas and the Differential Diagnosis With Metastatic Renal Cell Carcinoma

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