Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients

12 páginas

Autores:: Pasquale, Marta Francesca Di
Sotgiu, Giovanni
Gramegna, Andrea
Radovanovic, Dejan
Terraneo, Silvia
Reyes, Luis F.
Rupp, Jan
González del Castillo, Juan
Blasi, Francesco
Aliberti, Stefano

Tipo de recurso:

Fecha de publicación:: 2018

Institución:: Universidad de la Sabana

Repositorio:: Repositorio Universidad de la Sabana

Idioma:: eng

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dc.title.es_CO.fl_str_mv	Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients
title	Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients
spellingShingle	Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients Pneumonia Multidrug-resistant pathogens Microbiology
title_short	Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients
title_full	Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients
title_fullStr	Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients
title_full_unstemmed	Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients
title_sort	Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients
dc.creator.fl_str_mv	Pasquale, Marta Francesca Di Sotgiu, Giovanni Gramegna, Andrea Radovanovic, Dejan Terraneo, Silvia Reyes, Luis F. Rupp, Jan González del Castillo, Juan Blasi, Francesco Aliberti, Stefano
dc.contributor.author.none.fl_str_mv	Pasquale, Marta Francesca Di Sotgiu, Giovanni Gramegna, Andrea Radovanovic, Dejan Terraneo, Silvia Reyes, Luis F. Rupp, Jan González del Castillo, Juan Blasi, Francesco Aliberti, Stefano
dc.subject.other.en.fl_str_mv	Pneumonia Multidrug-resistant pathogens Microbiology
topic	Pneumonia Multidrug-resistant pathogens Microbiology
description	12 páginas
publishDate	2018
dc.date.accessioned.none.fl_str_mv	11/10/2020 10:28
dc.date.issued.none.fl_str_mv	2018-08-23
dc.date.available.none.fl_str_mv	2020-11-10T15:28:05Z
dc.type.en.fl_str_mv	article
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dc.identifier.citation.es_CO.fl_str_mv	Marta Francesca Di Pasquale, Giovanni Sotgiu, Andrea Gramegna, Dejan Radovanovic, Silvia Terraneo, Luis F Reyes, Jan Rupp, Juan González del Castillo, Francesco Blasi, Stefano Aliberti, Marcos I Restrepo, Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients, Clinical Infectious Diseases, Volume 68, Issue 9, 1 May 2019, Pages 1482–1493, https://doi.org/10.1093/cid/ciy723
dc.identifier.issn.none.fl_str_mv	1537-6591
dc.identifier.other.none.fl_str_mv	https://academic.oup.com/cid/article/68/9/1482/5078600
dc.identifier.uri.none.fl_str_mv	http://hdl.handle.net/10818/44035
dc.identifier.doi.none.fl_str_mv	10.1093/cid/ciy723
identifier_str_mv	Marta Francesca Di Pasquale, Giovanni Sotgiu, Andrea Gramegna, Dejan Radovanovic, Silvia Terraneo, Luis F Reyes, Jan Rupp, Juan González del Castillo, Francesco Blasi, Stefano Aliberti, Marcos I Restrepo, Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients, Clinical Infectious Diseases, Volume 68, Issue 9, 1 May 2019, Pages 1482–1493, https://doi.org/10.1093/cid/ciy723 1537-6591 10.1093/cid/ciy723
url	https://academic.oup.com/cid/article/68/9/1482/5078600 http://hdl.handle.net/10818/44035
dc.language.iso.es_CO.fl_str_mv	eng
language	eng
dc.relation.ispartofseries.none.fl_str_mv	Clinical Infectious Diseases, Volume 68, Issue 9, 1 May 2019, Pages 1482–1493
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dc.publisher.es_CO.fl_str_mv	Clinical Infectious Diseases
dc.source.es_CO.fl_str_mv	Universidad de La Sabana Intellectum Repositorio Universidad de La Sabana
institution	Universidad de la Sabana
bitstream.url.fl_str_mv	https://intellectum.unisabana.edu.co/bitstream/10818/44035/2/license_rdf https://intellectum.unisabana.edu.co/bitstream/10818/44035/3/license.txt
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spelling	Pasquale, Marta Francesca DiSotgiu, GiovanniGramegna, AndreaRadovanovic, DejanTerraneo, SilviaReyes, Luis F.Rupp, JanGonzález del Castillo, JuanBlasi, FrancescoAliberti, Stefano11/10/2020 10:282020-11-10T15:28:05Z2018-08-23Marta Francesca Di Pasquale, Giovanni Sotgiu, Andrea Gramegna, Dejan Radovanovic, Silvia Terraneo, Luis F Reyes, Jan Rupp, Juan González del Castillo, Francesco Blasi, Stefano Aliberti, Marcos I Restrepo, Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients, Clinical Infectious Diseases, Volume 68, Issue 9, 1 May 2019, Pages 1482–1493, https://doi.org/10.1093/cid/ciy7231537-6591https://academic.oup.com/cid/article/68/9/1482/5078600http://hdl.handle.net/10818/4403510.1093/cid/ciy72312 páginasBackground. The correct management of immunocompromised patients with pneumonia is debated. We evaluated the prevalence, risk factors, and characteristics of immunocompromised patients coming from the community with pneumonia. Methods. We conducted a secondary analysis of an international, multicenter study enrolling adult patients coming from the community with pneumonia and hospitalized in 222 hospitals in 54 countries worldwide. Risk factors for immunocompromise included AIDS, aplastic anemia, asplenia, hematological cancer, chemotherapy, neutropenia, biological drug use, lung transplantation, chronic steroid use, and solid tumor. Results. At least 1 risk factor for immunocompromise was recorded in 18% of the 3702 patients enrolled. The prevalences of risk factors significantly differed across continents and countries, with chronic steroid use (45%), hematological cancer (25%), and chemotherapy (22%) the most common. Among immunocompromised patients, community-acquired pneumonia (CAP) pathogens were the most frequently identified, and prevalences did not differ from those in immunocompetent patients. Risk factors for immunocompromise were independently associated with neither Pseudomonas aeruginosa nor non–community-acquired bacteria. Specific risk factors were independently associated with fungal infections (odds ratio for AIDS and hematological cancer, 15.10 and 4.65, respectively; both P = .001), mycobacterial infections (AIDS; P = .006), and viral infections other than influenza (hematological cancer, 5.49; P < .001). Conclusions. Our findings could be considered by clinicians in prescribing empiric antibiotic therapy for CAP in immunocompromised patients. Patients with AIDS and hematological cancer admitted with CAP may have higher prevalences of fungi, mycobacteria, and noninfluenza viruses.application/pdfengClinical Infectious DiseasesClinical Infectious Diseases, Volume 68, Issue 9, 1 May 2019, Pages 1482–1493Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/http://purl.org/coar/access_right/c_abf2Universidad de La SabanaIntellectum Repositorio Universidad de La SabanaPneumoniaMultidrug-resistant pathogensMicrobiologyPrevalence and Etiology of Community-acquired Pneumonia in Immunocompromised PatientsarticlepublishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8805https://intellectum.unisabana.edu.co/bitstream/10818/44035/2/license_rdf4460e5956bc1d1639be9ae6146a50347MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-8498https://intellectum.unisabana.edu.co/bitstream/10818/44035/3/license.txtf52a2cfd4df262e08e9b300d62c85cabMD5310818/44035oai:intellectum.unisabana.edu.co:10818/440352022-05-10 05:20:58.845Intellectum Universidad de la Sabanacontactointellectum@unisabana.edu.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

Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients

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