Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients

12 páginas

Autores:
Pasquale, Marta Francesca Di
Sotgiu, Giovanni
Gramegna, Andrea
Radovanovic, Dejan
Terraneo, Silvia
Reyes, Luis F.
Rupp, Jan
González del Castillo, Juan
Blasi, Francesco
Aliberti, Stefano
Tipo de recurso:
Fecha de publicación:
2018
Institución:
Universidad de la Sabana
Repositorio:
Repositorio Universidad de la Sabana
Idioma:
eng
OAI Identifier:
oai:intellectum.unisabana.edu.co:10818/44035
Acceso en línea:
https://academic.oup.com/cid/article/68/9/1482/5078600
http://hdl.handle.net/10818/44035
Palabra clave:
Pneumonia
Multidrug-resistant pathogens
Microbiology
Rights
License
Attribution-NonCommercial-NoDerivatives 4.0 International
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network_name_str Repositorio Universidad de la Sabana
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dc.title.es_CO.fl_str_mv Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients
title Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients
spellingShingle Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients
Pneumonia
Multidrug-resistant pathogens
Microbiology
title_short Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients
title_full Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients
title_fullStr Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients
title_full_unstemmed Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients
title_sort Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients
dc.creator.fl_str_mv Pasquale, Marta Francesca Di
Sotgiu, Giovanni
Gramegna, Andrea
Radovanovic, Dejan
Terraneo, Silvia
Reyes, Luis F.
Rupp, Jan
González del Castillo, Juan
Blasi, Francesco
Aliberti, Stefano
dc.contributor.author.none.fl_str_mv Pasquale, Marta Francesca Di
Sotgiu, Giovanni
Gramegna, Andrea
Radovanovic, Dejan
Terraneo, Silvia
Reyes, Luis F.
Rupp, Jan
González del Castillo, Juan
Blasi, Francesco
Aliberti, Stefano
dc.subject.other.en.fl_str_mv Pneumonia
Multidrug-resistant pathogens
Microbiology
topic Pneumonia
Multidrug-resistant pathogens
Microbiology
description 12 páginas
publishDate 2018
dc.date.accessioned.none.fl_str_mv 11/10/2020 10:28
dc.date.issued.none.fl_str_mv 2018-08-23
dc.date.available.none.fl_str_mv 2020-11-10T15:28:05Z
dc.type.en.fl_str_mv article
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dc.identifier.citation.es_CO.fl_str_mv Marta Francesca Di Pasquale, Giovanni Sotgiu, Andrea Gramegna, Dejan Radovanovic, Silvia Terraneo, Luis F Reyes, Jan Rupp, Juan González del Castillo, Francesco Blasi, Stefano Aliberti, Marcos I Restrepo, Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients, Clinical Infectious Diseases, Volume 68, Issue 9, 1 May 2019, Pages 1482–1493, https://doi.org/10.1093/cid/ciy723
dc.identifier.issn.none.fl_str_mv 1537-6591
dc.identifier.other.none.fl_str_mv https://academic.oup.com/cid/article/68/9/1482/5078600
dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10818/44035
dc.identifier.doi.none.fl_str_mv 10.1093/cid/ciy723
identifier_str_mv Marta Francesca Di Pasquale, Giovanni Sotgiu, Andrea Gramegna, Dejan Radovanovic, Silvia Terraneo, Luis F Reyes, Jan Rupp, Juan González del Castillo, Francesco Blasi, Stefano Aliberti, Marcos I Restrepo, Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients, Clinical Infectious Diseases, Volume 68, Issue 9, 1 May 2019, Pages 1482–1493, https://doi.org/10.1093/cid/ciy723
1537-6591
10.1093/cid/ciy723
url https://academic.oup.com/cid/article/68/9/1482/5078600
http://hdl.handle.net/10818/44035
dc.language.iso.es_CO.fl_str_mv eng
language eng
dc.relation.ispartofseries.none.fl_str_mv Clinical Infectious Diseases, Volume 68, Issue 9, 1 May 2019, Pages 1482–1493
dc.rights.*.fl_str_mv Attribution-NonCommercial-NoDerivatives 4.0 International
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dc.rights.uri.*.fl_str_mv http://creativecommons.org/licenses/by-nc-nd/4.0/
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http://creativecommons.org/licenses/by-nc-nd/4.0/
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dc.format.es_CO.fl_str_mv application/pdf
dc.publisher.es_CO.fl_str_mv Clinical Infectious Diseases
dc.source.es_CO.fl_str_mv Universidad de La Sabana
Intellectum Repositorio Universidad de La Sabana
institution Universidad de la Sabana
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spelling Pasquale, Marta Francesca DiSotgiu, GiovanniGramegna, AndreaRadovanovic, DejanTerraneo, SilviaReyes, Luis F.Rupp, JanGonzález del Castillo, JuanBlasi, FrancescoAliberti, Stefano11/10/2020 10:282020-11-10T15:28:05Z2018-08-23Marta Francesca Di Pasquale, Giovanni Sotgiu, Andrea Gramegna, Dejan Radovanovic, Silvia Terraneo, Luis F Reyes, Jan Rupp, Juan González del Castillo, Francesco Blasi, Stefano Aliberti, Marcos I Restrepo, Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients, Clinical Infectious Diseases, Volume 68, Issue 9, 1 May 2019, Pages 1482–1493, https://doi.org/10.1093/cid/ciy7231537-6591https://academic.oup.com/cid/article/68/9/1482/5078600http://hdl.handle.net/10818/4403510.1093/cid/ciy72312 páginasBackground. The correct management of immunocompromised patients with pneumonia is debated. We evaluated the prevalence, risk factors, and characteristics of immunocompromised patients coming from the community with pneumonia. Methods. We conducted a secondary analysis of an international, multicenter study enrolling adult patients coming from the community with pneumonia and hospitalized in 222 hospitals in 54 countries worldwide. Risk factors for immunocompromise included AIDS, aplastic anemia, asplenia, hematological cancer, chemotherapy, neutropenia, biological drug use, lung transplantation, chronic steroid use, and solid tumor. Results. At least 1 risk factor for immunocompromise was recorded in 18% of the 3702 patients enrolled. The prevalences of risk factors significantly differed across continents and countries, with chronic steroid use (45%), hematological cancer (25%), and chemotherapy (22%) the most common. Among immunocompromised patients, community-acquired pneumonia (CAP) pathogens were the most frequently identified, and prevalences did not differ from those in immunocompetent patients. Risk factors for immunocompromise were independently associated with neither Pseudomonas aeruginosa nor non–community-acquired bacteria. Specific risk factors were independently associated with fungal infections (odds ratio for AIDS and hematological cancer, 15.10 and 4.65, respectively; both P = .001), mycobacterial infections (AIDS; P = .006), and viral infections other than influenza (hematological cancer, 5.49; P < .001). Conclusions. Our findings could be considered by clinicians in prescribing empiric antibiotic therapy for CAP in immunocompromised patients. Patients with AIDS and hematological cancer admitted with CAP may have higher prevalences of fungi, mycobacteria, and noninfluenza viruses.application/pdfengClinical Infectious DiseasesClinical Infectious Diseases, Volume 68, Issue 9, 1 May 2019, Pages 1482–1493Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/http://purl.org/coar/access_right/c_abf2Universidad de La SabanaIntellectum Repositorio Universidad de La SabanaPneumoniaMultidrug-resistant pathogensMicrobiologyPrevalence and Etiology of Community-acquired Pneumonia in Immunocompromised PatientsarticlepublishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8805https://intellectum.unisabana.edu.co/bitstream/10818/44035/2/license_rdf4460e5956bc1d1639be9ae6146a50347MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-8498https://intellectum.unisabana.edu.co/bitstream/10818/44035/3/license.txtf52a2cfd4df262e08e9b300d62c85cabMD5310818/44035oai:intellectum.unisabana.edu.co:10818/440352022-05-10 05:20:58.845Intellectum Universidad de la Sabanacontactointellectum@unisabana.edu.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