Pure neuritic leprosy in patients from a high endemic region of Colombia

10 páginas

Autores:: Rodriguez, Gerzain
Pinto, Rafael
Gómez Parrado, Yenny Milena

Tipo de recurso:

Fecha de publicación:: 2013

Institución:: Universidad de la Sabana

Repositorio:: Repositorio Universidad de la Sabana

Idioma:: eng

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spelling	Rodriguez, GerzainPinto, RafaelGómez Parrado, Yenny Milena11/19/2020 10:212020-11-19T15:21:14Z2013-02-040305-7518https://www.researchgate.net/publication/237068233_Pure_neuritic_leprosy_in_patients_from_a_high_endemic_region_of_Colombiahttp://hdl.handle.net/10818/4465510 páginasAgua de Dios was a leprosarium for leprosy patients' obligatory isolation (1872-1961). Its leprosy incidence is the highest in Colombia (1.5-7/10000). Relapses are common. Government grant of US$ 200 per month subsidy is available to patients with disabilities. Spontaneous consultation with neural symptoms is frequent and simulation to get the subsidy has to be considered. We studied 36 subjects (2007-2009), with ages from 29-78, 19 of them men, with neural symptoms of 6 months to 20 years evolution. All had clinical examination, bacteriological examination, skin and nerve biopsies, electromyography (EMG), PCR for M. leprae, IgM anti-PGL1, and lepromin A. All but two are household contacts of leprosy patients. Symptoms were hypoesthesia of the hands and feet, and difficulty using hands with loss of muscular strength. None had skin lesions. Three had thickening of ulnar nerve. Lepromin was positive in all; bacteriology and biopsies were negative in all. The speed and amplitude of neural conduction were altered in 34 patients; two women had normal EMG and were considered to be feigning the disease; 21 were diagnosed as PNL by clinical, epidemiological and EMG findings; five of them had a positive PCR and one, high titers for IgM anti PGL1. Nine other subjects had diabetes and six carpal tunnel syndrome (CTS). Slow progression of disease, the lack of neural enlargement and the neural biopsies without inflammation suggest that most of these patients could have spontaneously cured PNL, as happens with other cases of paucibacillary leprosy. Diabetes and CTS are important differential diagnoses of PNL. Patients were treated with MDT and received the state subsidy.application/pdfengLeprosy reviewLeprosy review 84(1):41-50;Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/http://purl.org/coar/access_right/c_abf2Universidad de La SabanaIntellectum Repositorio Universidad de La SabanaLeprosyPatientsPure neuritic leprosy in patients from a high endemic region of ColombiaarticlepublishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8805https://intellectum.unisabana.edu.co/bitstream/10818/44655/2/license_rdf4460e5956bc1d1639be9ae6146a50347MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-8498https://intellectum.unisabana.edu.co/bitstream/10818/44655/3/license.txtf52a2cfd4df262e08e9b300d62c85cabMD5310818/44655oai:intellectum.unisabana.edu.co:10818/446552022-05-10 05:22:20.686Intellectum Universidad de la Sabanacontactointellectum@unisabana.edu.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
dc.title.es_CO.fl_str_mv	Pure neuritic leprosy in patients from a high endemic region of Colombia
title	Pure neuritic leprosy in patients from a high endemic region of Colombia
spellingShingle	Pure neuritic leprosy in patients from a high endemic region of Colombia Leprosy Patients
title_short	Pure neuritic leprosy in patients from a high endemic region of Colombia
title_full	Pure neuritic leprosy in patients from a high endemic region of Colombia
title_fullStr	Pure neuritic leprosy in patients from a high endemic region of Colombia
title_full_unstemmed	Pure neuritic leprosy in patients from a high endemic region of Colombia
title_sort	Pure neuritic leprosy in patients from a high endemic region of Colombia
dc.creator.fl_str_mv	Rodriguez, Gerzain Pinto, Rafael Gómez Parrado, Yenny Milena
dc.contributor.author.none.fl_str_mv	Rodriguez, Gerzain Pinto, Rafael Gómez Parrado, Yenny Milena
dc.subject.es_CO.fl_str_mv	Leprosy Patients
topic	Leprosy Patients
description	10 páginas
publishDate	2013
dc.date.accessioned.none.fl_str_mv	11/19/2020 10:21
dc.date.issued.none.fl_str_mv	2013-02-04
dc.date.available.none.fl_str_mv	2020-11-19T15:21:14Z
dc.type.en.fl_str_mv	article
dc.type.coarversion.fl_str_mv	http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv	http://purl.org/coar/resource_type/c_6501
dc.type.hasVersion.es_CO.fl_str_mv	publishedVersion
dc.identifier.issn.none.fl_str_mv	0305-7518
dc.identifier.other.none.fl_str_mv	https://www.researchgate.net/publication/237068233_Pure_neuritic_leprosy_in_patients_from_a_high_endemic_region_of_Colombia
dc.identifier.uri.none.fl_str_mv	http://hdl.handle.net/10818/44655
identifier_str_mv	0305-7518
url	https://www.researchgate.net/publication/237068233_Pure_neuritic_leprosy_in_patients_from_a_high_endemic_region_of_Colombia http://hdl.handle.net/10818/44655
dc.language.iso.es_CO.fl_str_mv	eng
language	eng
dc.relation.ispartofseries.none.fl_str_mv	Leprosy review 84(1):41-50;
dc.rights.*.fl_str_mv	Attribution-NonCommercial-NoDerivatives 4.0 International
dc.rights.coar.fl_str_mv	http://purl.org/coar/access_right/c_abf2
dc.rights.uri.*.fl_str_mv	http://creativecommons.org/licenses/by-nc-nd/4.0/
rights_invalid_str_mv	Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ http://purl.org/coar/access_right/c_abf2
dc.format.es_CO.fl_str_mv	application/pdf
dc.publisher.es_CO.fl_str_mv	Leprosy review
dc.source.es_CO.fl_str_mv	Universidad de La Sabana Intellectum Repositorio Universidad de La Sabana
institution	Universidad de la Sabana
bitstream.url.fl_str_mv	https://intellectum.unisabana.edu.co/bitstream/10818/44655/2/license_rdf https://intellectum.unisabana.edu.co/bitstream/10818/44655/3/license.txt
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Pure neuritic leprosy in patients from a high endemic region of Colombia

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