Perfil de prolactina y estradiol en una cohorte de mujeres colombianas con lupus eritematoso sistémico

60 Páginas.

Autores:
Aulestia Baldeón, Elcie Carolina
Tipo de recurso:
Fecha de publicación:
2013
Institución:
Universidad de la Sabana
Repositorio:
Repositorio Universidad de la Sabana
Idioma:
spa
OAI Identifier:
oai:intellectum.unisabana.edu.co:10818/9372
Acceso en línea:
http://hdl.handle.net/10818/9372
Palabra clave:
Prolatina -- Investigaciones
Estradiol
Lupus eritematoso cutáneo -- Piel -- Enfermedades
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License
http://purl.org/coar/access_right/c_abf2
id REPOUSABA2_92289c5dc144b467be7d24fb768e906c
oai_identifier_str oai:intellectum.unisabana.edu.co:10818/9372
network_acronym_str REPOUSABA2
network_name_str Repositorio Universidad de la Sabana
repository_id_str
dc.title.es_CO.fl_str_mv Perfil de prolactina y estradiol en una cohorte de mujeres colombianas con lupus eritematoso sistémico
title Perfil de prolactina y estradiol en una cohorte de mujeres colombianas con lupus eritematoso sistémico
spellingShingle Perfil de prolactina y estradiol en una cohorte de mujeres colombianas con lupus eritematoso sistémico
Prolatina -- Investigaciones
Estradiol
Lupus eritematoso cutáneo -- Piel -- Enfermedades
title_short Perfil de prolactina y estradiol en una cohorte de mujeres colombianas con lupus eritematoso sistémico
title_full Perfil de prolactina y estradiol en una cohorte de mujeres colombianas con lupus eritematoso sistémico
title_fullStr Perfil de prolactina y estradiol en una cohorte de mujeres colombianas con lupus eritematoso sistémico
title_full_unstemmed Perfil de prolactina y estradiol en una cohorte de mujeres colombianas con lupus eritematoso sistémico
title_sort Perfil de prolactina y estradiol en una cohorte de mujeres colombianas con lupus eritematoso sistémico
dc.creator.fl_str_mv Aulestia Baldeón, Elcie Carolina
dc.contributor.advisor.none.fl_str_mv Granados, Carlos Eduardo
Zubiría, Alberto de
dc.contributor.author.none.fl_str_mv Aulestia Baldeón, Elcie Carolina
dc.subject.none.fl_str_mv Prolatina -- Investigaciones
Estradiol
Lupus eritematoso cutáneo -- Piel -- Enfermedades
topic Prolatina -- Investigaciones
Estradiol
Lupus eritematoso cutáneo -- Piel -- Enfermedades
description 60 Páginas.
publishDate 2013
dc.date.accessioned.none.fl_str_mv 2013-12-16T17:54:36Z
dc.date.available.none.fl_str_mv 2013-12-16T17:54:36Z
dc.date.created.none.fl_str_mv 2013
dc.date.issued.none.fl_str_mv 2013-12-16
dc.type.none.fl_str_mv bachelorThesis
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_7a1f
dc.type.local.none.fl_str_mv Tesis de especialización
dc.type.hasVersion.none.fl_str_mv publishedVersion
dc.identifier.citation.none.fl_str_mv Clowse MEB. Lupus activity in pregnancy. Rheum. Dis. Clin. North Am. 2007 May;33(2):237–252, v.
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dc.identifier.uri.none.fl_str_mv http://hdl.handle.net/10818/9372
dc.identifier.local.none.fl_str_mv 256511
TE06227
identifier_str_mv Clowse MEB. Lupus activity in pregnancy. Rheum. Dis. Clin. North Am. 2007 May;33(2):237–252, v.
Kotzin BL. Systemic lupus erythematosus. Cell. 1996 May;85(3):303–6.
Szyper-Kravitz M, Zandman-Goddard G, Lahita RG, Shoenfeld Y. The neuroendocrine-immune interactions in systemic lupus erythematosus: a basis for understanding disease pathogenesis and complexity. Rheum. Dis. Clin. North Am. 2005 Feb;31(1):161–175, x
Nikpour M, Urowitz MB, Ibañez D, Gladman DD. Frequency and determinants of flare and persistently active disease in systemic lupus erythematosus. Arthritis Rheum. 2009;61(9):1152–8.
Petri M. Sex hormones and systemic lupus erythematosus. Lupus. 2008 May;17(5):412–5
Crow MK. Developments in the clinical understanding of lupus. Arthritis Res. Ther. 2009;11(5):245.
Cabrera JMA, D CAC, S RC, V PAC. Autoinmunidad y enfermedad autoinmune. Corporación para Investigaciones Biológicas; 2005. p. 557.
Lim SS, Drenkard C. Epidemiology of systemic lupus erythematosus: capturing the butterfly. Curr. Rheumatol. Rep. 2008 Aug;10(4):265–72
Pons-Estel GJ, Alarcón GS, Scofield L, Reinlib L, Cooper GS. Understanding the epidemiology and progression of systemic lupus erythematosus. Semin. Arthritis Rheum. 2010 Feb;39(4):257–68.
Tikly M, Navarra S V. Lupus in the developing world--is it any different? Best Pract. Res. Clin. Rheumatol. 2008 Aug;22(4):643–55.
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spelling Granados, Carlos EduardoZubiría, Alberto deAulestia Baldeón, Elcie CarolinaEspecialista en Medicina Interna2013-12-16T17:54:36Z2013-12-16T17:54:36Z20132013-12-16Clowse MEB. Lupus activity in pregnancy. Rheum. Dis. Clin. North Am. 2007 May;33(2):237–252, v.Kotzin BL. Systemic lupus erythematosus. Cell. 1996 May;85(3):303–6.Szyper-Kravitz M, Zandman-Goddard G, Lahita RG, Shoenfeld Y. The neuroendocrine-immune interactions in systemic lupus erythematosus: a basis for understanding disease pathogenesis and complexity. Rheum. Dis. Clin. North Am. 2005 Feb;31(1):161–175, xNikpour M, Urowitz MB, Ibañez D, Gladman DD. Frequency and determinants of flare and persistently active disease in systemic lupus erythematosus. Arthritis Rheum. 2009;61(9):1152–8.Petri M. Sex hormones and systemic lupus erythematosus. Lupus. 2008 May;17(5):412–5Crow MK. Developments in the clinical understanding of lupus. Arthritis Res. Ther. 2009;11(5):245.Cabrera JMA, D CAC, S RC, V PAC. Autoinmunidad y enfermedad autoinmune. Corporación para Investigaciones Biológicas; 2005. p. 557.Lim SS, Drenkard C. Epidemiology of systemic lupus erythematosus: capturing the butterfly. Curr. Rheumatol. Rep. 2008 Aug;10(4):265–72Pons-Estel GJ, Alarcón GS, Scofield L, Reinlib L, Cooper GS. Understanding the epidemiology and progression of systemic lupus erythematosus. Semin. Arthritis Rheum. 2010 Feb;39(4):257–68.Tikly M, Navarra S V. Lupus in the developing world--is it any different? Best Pract. Res. Clin. Rheumatol. 2008 Aug;22(4):643–55.Vasudevan A, Krishnamurthy AN. Changing worldwide epidemiology of systemic lupus erythematosus. Rheum. Dis. Clin. North Am. 2010 Feb;36(1):1–13, vii.Tan EM, Cohen AS, Fries JF, Masi AT, McShane DJ, Rothfield NF, et al. The 1982 revised criteria for the classification of systemic lupus erythematosus. Arthritis Rheum. 1982 Nov;25(11):1271–7.Crow MK. MD Consult: Goldman: Cecil Medicine, 23rd ed. [Internet]. 2007 [cited 2011 Jan 15]. 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Self-reported flaring varies during the menstrual cycle in systemic lupus erythematosus compared with rheumatoid arthritis and fibromyalgia. Rheumatology (Oxford). 2011 Apr;50(4):703–8http://hdl.handle.net/10818/9372256511TE0622760 Páginas.El Lupus Eritematoso Sistémico (LES) es un una enfermedad autoinmune con afectación multisistémica de gran variabilidad en su presentación y curso. Su diagnóstico se basa en características clínicas y de laboratorio en ausencia de otra enfermedad autoinmune que pueda explicar dichos hallazgos. Aunque el LES puede desarrollarse a cualquier edad, las mujeres en edad fértil son las principalmente afectadas. La relación mujer/hombre entre los 15 y 50 años de edad es > 8:1, mientras que llega a ser hasta 2:1 cuando ocurre durante la niñez o después de la menopausia. Esta prevalencia observada tanto en pacientes como en modelos animales, ha llevado a plantear la intervención de hormonas en el desarrollo y actividad de la misma. La relación entre el sistema neuroendocrino y el sistema inmune ha sido ampliamente demostrada. Comparten una red de conexiones mediadas por vías nerviosas, circuitos hormonales, interacciones celulares y humorales, así como una multitud de citoquinas, neuropéotidos y quemoquinas. De una interacción recíproca y modulada entre ambos sistemas depende el mantenimiento de la homeostasis. El desarrollo de una enfermedad multisistémica como el LES es el resultado del rompimiento de la misma. El LES se caracteriza por periodos de exacerbaciones y remisiones de la actividad de la enfermedad. Varios determinantes de este comportamiento han sido estudiados, sin que se haya esclarecido uno en especial; sin embargo, derivado de estudios observacionales de estados fisiológicos relacionados con aumento de actividad (por ejemplo, el embarazo) varios autores han demostrado la asociación con algunas hormonas. Entre las principales que han demostrado tener un efecto inmuno-modulador se encuentran el estrógeno y la prolactina.spaUniversidad de La SabanaEspecialización en Medicina InternaFacultad de MedicinaUniversidad de La SabanaIntellectum Repositorio Universidad de La SabanaProlatina -- InvestigacionesEstradiolLupus eritematoso cutáneo -- Piel -- EnfermedadesPerfil de prolactina y estradiol en una cohorte de mujeres colombianas con lupus eritematoso sistémicobachelorThesisTesis de especializaciónpublishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_7a1fhttp://purl.org/coar/access_right/c_abf2LICENSElicense.txtlicense.txttext/plain; charset=utf-8498https://intellectum.unisabana.edu.co/bitstream/10818/9372/2/license.txtf52a2cfd4df262e08e9b300d62c85cabMD52Elcie Carolina Aulestia Baldeón (Carta 1).pdfElcie Carolina Aulestia Baldeón (Carta 1).pdfapplication/pdf379802https://intellectum.unisabana.edu.co/bitstream/10818/9372/5/Elcie%20Carolina%20Aulestia%20Balde%c3%b3n%20%28Carta%201%29.pdf8c7a67cd6fc21883c8de7aba8a3c39f0MD55Elcie Carolina Aulestia Baldeón (Carta 2).pdfElcie Carolina Aulestia Baldeón (Carta 2).pdfapplication/pdf159622https://intellectum.unisabana.edu.co/bitstream/10818/9372/6/Elcie%20Carolina%20Aulestia%20Balde%c3%b3n%20%28Carta%202%29.pdf5d106558e1607a577e96767539702247MD56ORIGINALElcie Carolina Aulestia Baldeón FINAL.pdfElcie Carolina Aulestia Baldeón FINAL.pdfVer documento en PDFapplication/pdf1664375https://intellectum.unisabana.edu.co/bitstream/10818/9372/3/Elcie%20Carolina%20Aulestia%20Balde%c3%b3n%20FINAL.pdf818da8cdd6d65332dcb9ff9bf061f758MD53TEXTElcie Carolina Aulestia Baldeón FINAL.pdf.txtElcie Carolina Aulestia Baldeón FINAL.pdf.txtExtracted Texttext/plain61https://intellectum.unisabana.edu.co/bitstream/10818/9372/4/Elcie%20Carolina%20Aulestia%20Balde%c3%b3n%20FINAL.pdf.txt173796950fb380beab4a5451d5eb6a18MD5410818/9372oai:intellectum.unisabana.edu.co:10818/93722019-08-13 15:36:17.997Intellectum Universidad de la Sabanacontactointellectum@unisabana.edu.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