Prevalencia de apnea compleja en pacientes remitidos a titulación de C-Pap en una ciudad a 2640 metros sobre el nivel del mar

55 Páginas.

Autores:
Martínez Guzmán, William
Bazurto Zapata, María Angélica
Herrera Nieto, Karen Lorena
González García, Mauricio
Tipo de recurso:
Fecha de publicación:
2012
Institución:
Universidad de la Sabana
Repositorio:
Repositorio Universidad de la Sabana
Idioma:
spa
OAI Identifier:
oai:intellectum.unisabana.edu.co:10818/8197
Acceso en línea:
http://hdl.handle.net/10818/8197
Palabra clave:
Apnea del sueño obstructiva
Apnea del sueño obstructiva-Investigaciones-Bogotá (Colombia)
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License
http://purl.org/coar/access_right/c_abf2
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network_name_str Repositorio Universidad de la Sabana
repository_id_str
dc.title.es_CO.fl_str_mv Prevalencia de apnea compleja en pacientes remitidos a titulación de C-Pap en una ciudad a 2640 metros sobre el nivel del mar
title Prevalencia de apnea compleja en pacientes remitidos a titulación de C-Pap en una ciudad a 2640 metros sobre el nivel del mar
spellingShingle Prevalencia de apnea compleja en pacientes remitidos a titulación de C-Pap en una ciudad a 2640 metros sobre el nivel del mar
Apnea del sueño obstructiva
Apnea del sueño obstructiva-Investigaciones-Bogotá (Colombia)
title_short Prevalencia de apnea compleja en pacientes remitidos a titulación de C-Pap en una ciudad a 2640 metros sobre el nivel del mar
title_full Prevalencia de apnea compleja en pacientes remitidos a titulación de C-Pap en una ciudad a 2640 metros sobre el nivel del mar
title_fullStr Prevalencia de apnea compleja en pacientes remitidos a titulación de C-Pap en una ciudad a 2640 metros sobre el nivel del mar
title_full_unstemmed Prevalencia de apnea compleja en pacientes remitidos a titulación de C-Pap en una ciudad a 2640 metros sobre el nivel del mar
title_sort Prevalencia de apnea compleja en pacientes remitidos a titulación de C-Pap en una ciudad a 2640 metros sobre el nivel del mar
dc.creator.fl_str_mv Martínez Guzmán, William
Bazurto Zapata, María Angélica
Herrera Nieto, Karen Lorena
González García, Mauricio
dc.contributor.author.none.fl_str_mv Martínez Guzmán, William
Bazurto Zapata, María Angélica
Herrera Nieto, Karen Lorena
González García, Mauricio
dc.subject.es_CO.fl_str_mv Apnea del sueño obstructiva
Apnea del sueño obstructiva-Investigaciones-Bogotá (Colombia)
topic Apnea del sueño obstructiva
Apnea del sueño obstructiva-Investigaciones-Bogotá (Colombia)
description 55 Páginas.
publishDate 2012
dc.date.created.none.fl_str_mv 2012
dc.date.accessioned.none.fl_str_mv 2013-07-31T21:31:53Z
dc.date.available.none.fl_str_mv 2013-07-31T21:31:53Z
dc.date.issued.none.fl_str_mv 2013-07-31
dc.type.none.fl_str_mv bachelorThesis
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_7a1f
dc.type.local.none.fl_str_mv Tesis de especialización
dc.type.hasVersion.none.fl_str_mv publishedVersion
dc.identifier.citation.none.fl_str_mv Torres C, Maldonado DG. Fundamentos de medicina. Neumología. CIB. Trastornos respiratorios durante el sueño y síndromes de hipo ventilación alveolar. Capítulo 15°. 6a ed. 2007.
Arzt M, Bradley D. Treatment of Sleep Apnea in Heart Failure. Am J RespirCrit Care Med. 2006. Vol 173. pp 1300–1308.
Gilmartin GS. Recognition and management of complex sleep-disordered breathing. Current Opinion in Pulmonary Medicine.2005. 11:485—493.
Gay PC. Complex Sleep Apnea: It Really Is a Disease. Journal of Clinical Sleep Medicine.2008. Vol. 4, No. 5
Morgenthaler T, KagramanovV, HanakV, et al. Complex sleep apnea syndrome: is it a unique clinical syndrome? Sleep 2006. 29:1203-8.
Khan A et. al. Complex sleep apnea. PCCU. American College of Chest Physicians.2008
Pagel, KwiatkowskiC. The Effects of Altitude Associated Central Apnea on the Diagnosis and Treatment of Obstructive Sleep Apnea: Comparative Data from Three Different Altitude Locations in the Mountain West. Journal of Clinical Sleep Medicine. 2011. Vol. 7, No. 6.
White DP. Pathogenesis of Obstructive and Central Sleep Apnea. Am J RespirCrit Care Med 2005. Vol 172. pp 1363–1370.
Atlas de Trastornos respiratorios del Sueño. Conceptos básicos. Capitulo 6° Síndrome de Apnea Obstructiva del Sueño. pp 71 – 93.
Eckert DJ. Central Sleep Apnea. Pathophysiology and Treatment. CHEST 2007; 131:595–607.
Javaheri S. The Prevalence and Natural History of Complex Sleep Apnea J Clin Sleep Med 2009; 5(3):205-211.
Joanne Shirine, A. Efficacy of Adaptive Servo ventilation in Treatment of Complex and Central Sleep Apnea Syndromes CHEST 2007; 132:1839–1846.
Pusalavidyasagar SS, OlsonEJ, Gay PC, et al. Treatment of complex sleep apnea syndrome: a retrospective comparative review. Sleep Med 2006; 7:474-479.
Malhotra A. Complex Sleep Apnea: It Isn’t Really a Disease. Journal of sleep medicine. 2008. Vol. 4, No. 5.
A Technologist’s Handbook for Understanding and Implementing. The AASM Manual for the Scoring of Sleep and Associated Events. Rules, Terminology and Technical Specifications. Westchester, Illinois: American Academy of Sleep Medicin, 2009.
Mcnicholas WT. Diagnosis of Obstructive Sleep Apnea in Adults. Proc Am ThoracSoc 2008. Vol 5. pp 154–160.
Nguyen ATD, Baltzan M, Small D. et al. Clinical reproducibility of the epworth sleepiness scale. J Clin Sleep Med2006;2(2):170-174.
Gottlieb DJ, Yao Q, Redline S, Ali T, MahowaldMW. Does snoring predict sleepiness independently of apnea and hypopnea frequency? Am J RespirCrit Care Med 2000;162:1512–1517.
Szalai VS, HoffsteinV. Are history and physical examination a good screening test for sleep apnea? AnnInternMed 1991;115:356–359.
Flemons WW, McnicholasWT. Clinical prediction of the sleep apnea syndrome. Sleep Med Rev 1997;1:19–32.
Lemeshow S, HosmerD, KLAR J, LwaagaS. Adecuacy of Sample Size in Health Studies. John Wiley & Sons. New York. Tomasz J. 1990.
Lehman S, Anic N, Thompson C, et al. Central sleep apnea on commencement of continuous positive airway pressure in patient with primary diagnosis of obstructive sleep apnea-hyperpnoea. J Clin Sleep Med 2007;3:462-6.
Endo Y, Suzuki M, Yuichi I. et al. Prevalence of complex Sleep Apnea Among Japanese Patient with Sleep Apnea Syndrome. Tohoku J. Exp. Med., 2008, 215 (4), 349-354.
Westhoff M, Arzt M,Litterst P. Prevalence and treatment of central sleep apnoea emerging after initiation of continuous positive airway pressure in patients with obstructive sleep apnoea without evidence of heart failure. Sleep Breath;feb 2012,vol 16 Issue 1,p71.
Nakayama H, Smith CA, Rodman JR, SkatrudJB, Dempsey JA. Effect of ventilatory drive on carbon dioxide sensitivity below eupnoea during sleep. Am J RespirCrit Care Med 2002;165:1251-9.
Dernaika T, TawkM, NazirS, et al. The significance and outcome of continuous positive airway pressure-related central sleep apnea during split-night sleep studies. Chest 2007;132:81-8.
Sanders MH. Positive Pressure Therapy A Perspective on Evidence-based Outcomes and Methods of Application. Proc Am Thorac Soc. 2008. Vol 5.pp 161–172.
Benjamin JA. Sleep-disordered breathing and cardiovascular disease.Postgrad. Med. J. 2008;84;15-22.
Kuzniar. Natural course of complex sleep apnea—a retrospective. Study Sleep Breath. 2008. 12:135–139J.F.
Mcnichols W, Carter J, Rutherford R, et al. Beneficial effect of oxygen in primary alveolar hypoventilation with central sleep apnea. Am Rev Respir Dis.1982. 125:773- 5.
White DP. Central sleep apnea. Med Clin North Am1985;69:1205-19
Mees K, Chaux R. Polygraphy of sleep at altitudes between 5300 m and 7500 m during an expedition to Mt. Everest. Wilderness Environ Med 2009;20:161-5
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identifier_str_mv Torres C, Maldonado DG. Fundamentos de medicina. Neumología. CIB. Trastornos respiratorios durante el sueño y síndromes de hipo ventilación alveolar. Capítulo 15°. 6a ed. 2007.
Arzt M, Bradley D. Treatment of Sleep Apnea in Heart Failure. Am J RespirCrit Care Med. 2006. Vol 173. pp 1300–1308.
Gilmartin GS. Recognition and management of complex sleep-disordered breathing. Current Opinion in Pulmonary Medicine.2005. 11:485—493.
Gay PC. Complex Sleep Apnea: It Really Is a Disease. Journal of Clinical Sleep Medicine.2008. Vol. 4, No. 5
Morgenthaler T, KagramanovV, HanakV, et al. Complex sleep apnea syndrome: is it a unique clinical syndrome? Sleep 2006. 29:1203-8.
Khan A et. al. Complex sleep apnea. PCCU. American College of Chest Physicians.2008
Pagel, KwiatkowskiC. The Effects of Altitude Associated Central Apnea on the Diagnosis and Treatment of Obstructive Sleep Apnea: Comparative Data from Three Different Altitude Locations in the Mountain West. Journal of Clinical Sleep Medicine. 2011. Vol. 7, No. 6.
White DP. Pathogenesis of Obstructive and Central Sleep Apnea. Am J RespirCrit Care Med 2005. Vol 172. pp 1363–1370.
Atlas de Trastornos respiratorios del Sueño. Conceptos básicos. Capitulo 6° Síndrome de Apnea Obstructiva del Sueño. pp 71 – 93.
Eckert DJ. Central Sleep Apnea. Pathophysiology and Treatment. CHEST 2007; 131:595–607.
Javaheri S. The Prevalence and Natural History of Complex Sleep Apnea J Clin Sleep Med 2009; 5(3):205-211.
Joanne Shirine, A. Efficacy of Adaptive Servo ventilation in Treatment of Complex and Central Sleep Apnea Syndromes CHEST 2007; 132:1839–1846.
Pusalavidyasagar SS, OlsonEJ, Gay PC, et al. Treatment of complex sleep apnea syndrome: a retrospective comparative review. Sleep Med 2006; 7:474-479.
Malhotra A. Complex Sleep Apnea: It Isn’t Really a Disease. Journal of sleep medicine. 2008. Vol. 4, No. 5.
A Technologist’s Handbook for Understanding and Implementing. The AASM Manual for the Scoring of Sleep and Associated Events. Rules, Terminology and Technical Specifications. Westchester, Illinois: American Academy of Sleep Medicin, 2009.
Mcnicholas WT. Diagnosis of Obstructive Sleep Apnea in Adults. Proc Am ThoracSoc 2008. Vol 5. pp 154–160.
Nguyen ATD, Baltzan M, Small D. et al. Clinical reproducibility of the epworth sleepiness scale. J Clin Sleep Med2006;2(2):170-174.
Gottlieb DJ, Yao Q, Redline S, Ali T, MahowaldMW. Does snoring predict sleepiness independently of apnea and hypopnea frequency? Am J RespirCrit Care Med 2000;162:1512–1517.
Szalai VS, HoffsteinV. Are history and physical examination a good screening test for sleep apnea? AnnInternMed 1991;115:356–359.
Flemons WW, McnicholasWT. Clinical prediction of the sleep apnea syndrome. Sleep Med Rev 1997;1:19–32.
Lemeshow S, HosmerD, KLAR J, LwaagaS. Adecuacy of Sample Size in Health Studies. John Wiley & Sons. New York. Tomasz J. 1990.
Lehman S, Anic N, Thompson C, et al. Central sleep apnea on commencement of continuous positive airway pressure in patient with primary diagnosis of obstructive sleep apnea-hyperpnoea. J Clin Sleep Med 2007;3:462-6.
Endo Y, Suzuki M, Yuichi I. et al. Prevalence of complex Sleep Apnea Among Japanese Patient with Sleep Apnea Syndrome. Tohoku J. Exp. Med., 2008, 215 (4), 349-354.
Westhoff M, Arzt M,Litterst P. Prevalence and treatment of central sleep apnoea emerging after initiation of continuous positive airway pressure in patients with obstructive sleep apnoea without evidence of heart failure. Sleep Breath;feb 2012,vol 16 Issue 1,p71.
Nakayama H, Smith CA, Rodman JR, SkatrudJB, Dempsey JA. Effect of ventilatory drive on carbon dioxide sensitivity below eupnoea during sleep. Am J RespirCrit Care Med 2002;165:1251-9.
Dernaika T, TawkM, NazirS, et al. The significance and outcome of continuous positive airway pressure-related central sleep apnea during split-night sleep studies. Chest 2007;132:81-8.
Sanders MH. Positive Pressure Therapy A Perspective on Evidence-based Outcomes and Methods of Application. Proc Am Thorac Soc. 2008. Vol 5.pp 161–172.
Benjamin JA. Sleep-disordered breathing and cardiovascular disease.Postgrad. Med. J. 2008;84;15-22.
Kuzniar. Natural course of complex sleep apnea—a retrospective. Study Sleep Breath. 2008. 12:135–139J.F.
Mcnichols W, Carter J, Rutherford R, et al. Beneficial effect of oxygen in primary alveolar hypoventilation with central sleep apnea. Am Rev Respir Dis.1982. 125:773- 5.
White DP. Central sleep apnea. Med Clin North Am1985;69:1205-19
Mees K, Chaux R. Polygraphy of sleep at altitudes between 5300 m and 7500 m during an expedition to Mt. Everest. Wilderness Environ Med 2009;20:161-5
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dc.publisher.program.none.fl_str_mv Especialización en Neumología
dc.publisher.department.none.fl_str_mv Facultad de Medicina
publisher.none.fl_str_mv Universidad de la Sabana
dc.source.none.fl_str_mv Universidad de La Sabana
Intellectum Repositorio Universidad de La Sabana
institution Universidad de la Sabana
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spelling Martínez Guzmán, WilliamBazurto Zapata, María AngélicaHerrera Nieto, Karen LorenaGonzález García, MauricioEspecialista en Neumología2013-07-31T21:31:53Z2013-07-31T21:31:53Z20122013-07-31Torres C, Maldonado DG. Fundamentos de medicina. Neumología. CIB. Trastornos respiratorios durante el sueño y síndromes de hipo ventilación alveolar. Capítulo 15°. 6a ed. 2007.Arzt M, Bradley D. Treatment of Sleep Apnea in Heart Failure. Am J RespirCrit Care Med. 2006. Vol 173. pp 1300–1308.Gilmartin GS. Recognition and management of complex sleep-disordered breathing. Current Opinion in Pulmonary Medicine.2005. 11:485—493.Gay PC. Complex Sleep Apnea: It Really Is a Disease. Journal of Clinical Sleep Medicine.2008. Vol. 4, No. 5Morgenthaler T, KagramanovV, HanakV, et al. Complex sleep apnea syndrome: is it a unique clinical syndrome? Sleep 2006. 29:1203-8.Khan A et. al. Complex sleep apnea. PCCU. American College of Chest Physicians.2008Pagel, KwiatkowskiC. The Effects of Altitude Associated Central Apnea on the Diagnosis and Treatment of Obstructive Sleep Apnea: Comparative Data from Three Different Altitude Locations in the Mountain West. Journal of Clinical Sleep Medicine. 2011. Vol. 7, No. 6.White DP. Pathogenesis of Obstructive and Central Sleep Apnea. Am J RespirCrit Care Med 2005. Vol 172. pp 1363–1370.Atlas de Trastornos respiratorios del Sueño. Conceptos básicos. Capitulo 6° Síndrome de Apnea Obstructiva del Sueño. pp 71 – 93.Eckert DJ. Central Sleep Apnea. Pathophysiology and Treatment. CHEST 2007; 131:595–607.Javaheri S. The Prevalence and Natural History of Complex Sleep Apnea J Clin Sleep Med 2009; 5(3):205-211.Joanne Shirine, A. Efficacy of Adaptive Servo ventilation in Treatment of Complex and Central Sleep Apnea Syndromes CHEST 2007; 132:1839–1846.Pusalavidyasagar SS, OlsonEJ, Gay PC, et al. Treatment of complex sleep apnea syndrome: a retrospective comparative review. Sleep Med 2006; 7:474-479.Malhotra A. Complex Sleep Apnea: It Isn’t Really a Disease. Journal of sleep medicine. 2008. Vol. 4, No. 5.A Technologist’s Handbook for Understanding and Implementing. The AASM Manual for the Scoring of Sleep and Associated Events. Rules, Terminology and Technical Specifications. Westchester, Illinois: American Academy of Sleep Medicin, 2009.Mcnicholas WT. Diagnosis of Obstructive Sleep Apnea in Adults. Proc Am ThoracSoc 2008. Vol 5. pp 154–160.Nguyen ATD, Baltzan M, Small D. et al. Clinical reproducibility of the epworth sleepiness scale. J Clin Sleep Med2006;2(2):170-174.Gottlieb DJ, Yao Q, Redline S, Ali T, MahowaldMW. Does snoring predict sleepiness independently of apnea and hypopnea frequency? Am J RespirCrit Care Med 2000;162:1512–1517.Szalai VS, HoffsteinV. Are history and physical examination a good screening test for sleep apnea? AnnInternMed 1991;115:356–359.Flemons WW, McnicholasWT. Clinical prediction of the sleep apnea syndrome. Sleep Med Rev 1997;1:19–32.Lemeshow S, HosmerD, KLAR J, LwaagaS. Adecuacy of Sample Size in Health Studies. John Wiley & Sons. New York. Tomasz J. 1990.Lehman S, Anic N, Thompson C, et al. Central sleep apnea on commencement of continuous positive airway pressure in patient with primary diagnosis of obstructive sleep apnea-hyperpnoea. J Clin Sleep Med 2007;3:462-6.Endo Y, Suzuki M, Yuichi I. et al. Prevalence of complex Sleep Apnea Among Japanese Patient with Sleep Apnea Syndrome. Tohoku J. Exp. Med., 2008, 215 (4), 349-354.Westhoff M, Arzt M,Litterst P. Prevalence and treatment of central sleep apnoea emerging after initiation of continuous positive airway pressure in patients with obstructive sleep apnoea without evidence of heart failure. Sleep Breath;feb 2012,vol 16 Issue 1,p71.Nakayama H, Smith CA, Rodman JR, SkatrudJB, Dempsey JA. Effect of ventilatory drive on carbon dioxide sensitivity below eupnoea during sleep. Am J RespirCrit Care Med 2002;165:1251-9.Dernaika T, TawkM, NazirS, et al. The significance and outcome of continuous positive airway pressure-related central sleep apnea during split-night sleep studies. Chest 2007;132:81-8.Sanders MH. Positive Pressure Therapy A Perspective on Evidence-based Outcomes and Methods of Application. Proc Am Thorac Soc. 2008. Vol 5.pp 161–172.Benjamin JA. Sleep-disordered breathing and cardiovascular disease.Postgrad. Med. J. 2008;84;15-22.Kuzniar. Natural course of complex sleep apnea—a retrospective. Study Sleep Breath. 2008. 12:135–139J.F.Mcnichols W, Carter J, Rutherford R, et al. Beneficial effect of oxygen in primary alveolar hypoventilation with central sleep apnea. Am Rev Respir Dis.1982. 125:773- 5.White DP. Central sleep apnea. Med Clin North Am1985;69:1205-19Mees K, Chaux R. Polygraphy of sleep at altitudes between 5300 m and 7500 m during an expedition to Mt. Everest. Wilderness Environ Med 2009;20:161-5http://hdl.handle.net/10818/8197254675TE0596555 Páginas.El síndrome apnea compleja (AC) se define como aparición de apneas centrales al aplicar presión positiva a pacientes con síndrome de apnea obstructiva. El desarrollo de AC ocasiona mala adherencia al tratamiento y síntomas persistentes. La AC podría ser más frecuente a la altura de Bogotá. Este estudio evaluó prevalencia de AC en adultos remitidos para titulación de CPAP en paciente con apnea obstructiva y la presencia de factores clínicos y del polisomnograma basal asociados. En 988 pacientes analizados, la prevalencia 11.6%. Requirieron mayor presión terapéutica (CPAP) presentan mayor índice de alertamientos (p < 0.001). Los factores asociados fueron apneas centrales en polisomnograma basal OR: 5.34 [3.49-8.17], antecedente de falla cardiaca OR: 2.53 [1.58-4.07] y sexo masculino OR: 1.72 [1.05-2.96]. Nota:spaUniversidad de la SabanaEspecialización en NeumologíaFacultad de MedicinaUniversidad de La SabanaIntellectum Repositorio Universidad de La SabanaApnea del sueño obstructivaApnea del sueño obstructiva-Investigaciones-Bogotá (Colombia)Prevalencia de apnea compleja en pacientes remitidos a titulación de C-Pap en una ciudad a 2640 metros sobre el nivel del marbachelorThesisTesis de especializaciónpublishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_7a1fhttp://purl.org/coar/access_right/c_abf2ORIGINALWILLIAM MARTÍNEZ GUZMÁN (T) FINAL.pdfWILLIAM MARTÍNEZ GUZMÁN (T) FINAL.pdfVer documento en PDFapplication/pdf474583https://intellectum.unisabana.edu.co/bitstream/10818/8197/3/WILLIAM%20MART%c3%8dNEZ%20GUZM%c3%81N%20%28T%29%20FINAL.pdf40c89fd30b217292fe9dfdfd571cc33fMD53LICENSElicense.txtlicense.txttext/plain; charset=utf-8498https://intellectum.unisabana.edu.co/bitstream/10818/8197/2/license.txtf52a2cfd4df262e08e9b300d62c85cabMD52William Martínez Guzmán (Carta).pdfWilliam Martínez Guzmán (Carta).pdfapplication/pdf1058927https://intellectum.unisabana.edu.co/bitstream/10818/8197/5/William%20Mart%c3%adnez%20Guzm%c3%a1n%20%28Carta%29.pdf1a83c8d7bc1bbac4610b8bc6a743c11fMD55TEXTWILLIAM MARTÍNEZ GUZMÁN (T) FINAL.pdf.txtWILLIAM MARTÍNEZ GUZMÁN (T) FINAL.pdf.txtExtracted Texttext/plain65https://intellectum.unisabana.edu.co/bitstream/10818/8197/4/WILLIAM%20MART%c3%8dNEZ%20GUZM%c3%81N%20%28T%29%20FINAL.pdf.txt354c8dc947dfb8326fdab6eb849edfafMD5410818/8197oai:intellectum.unisabana.edu.co:10818/81972019-12-16 11:05:28.965Intellectum Universidad de la Sabanacontactointellectum@unisabana.edu.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