The efficacy and safety of estriol to treat vulvovaginal atrophy in postmenopausal women: a systematic literature review

11 páginas

Autores:: Rueda, C.
Osorio, A. M.
Avellaneda, A. C.
Pinzón Flórez, Carlos Eduardo
Restrepo Castro, Olga Isabel

Tipo de recurso:

Fecha de publicación:: 2017

Institución:: Universidad de la Sabana

Repositorio:: Repositorio Universidad de la Sabana

Idioma:: eng

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spelling	Rueda, C.Osorio, A. M.Avellaneda, A. C.Pinzón Flórez, Carlos EduardoRestrepo Castro, Olga Isabel8/23/2019 9:272019-08-23T14:27:17Z2017-06C. Rueda, A. M. Osorio, A. C. Avellaneda, C. E. Pinzón & O. I. Restrepo (2017) The efficacy and safety of estriol to treat vulvovaginal atrophy in postmenopausal women: a systematic literature review, Climacteric, 20:4, 321-330, DOI: 10.1080/13697137.2017.13292911473-0804https://www.tandfonline.com/doi/full/10.1080/13697137.2017.1329291http://hdl.handle.net/10818/3679910.1080/13697137.2017.132929111 páginasObjectives: To evaluate the efficacy and safety of estriol for the treatment of vulvovaginal atrophy in postmenopausal women. Methods: A systematic literature review was performed. We searched the following electronic databases: Medline, Cochrane, Embase, Lilacs, CINHAL and Google Scholar. The studies selected included controlled clinical trials and quasi-experimental studies. Selections were made in pairs and independently, first by title and abstract and then complete texts. Results: We identified 188 studies, 22 of which met the inclusion criteria; 13 were controlled clinical trials and nine were quasi-experimental, and 1217 women were included. These studies confirmed the efficacy of local estrogens to treat symptoms of vulvovaginal atrophy with few adverse effects reported. Following treatment, serum estriol levels rose, peaking at 1 h. At the 6-month follow-up, there was no increase in serum estriol in treated women. Conclusions: The available evidence (of low and moderate quality) shows that, when administered vaginally, estriol preparations appear to be safe for women who have risk factors related to systemic estrogen therapy.application/pdfengJournal ClimactericJournal Climacteric 2017 V. 20, N. 4, 321–330Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/http://purl.org/coar/access_right/c_abf2Universidad de La SabanaIntellectum Repositorio Universidad de La SabanaEstriolVulvovaginal atrophySystematic literature reviewThe efficacy and safety of estriol to treat vulvovaginal atrophy in postmenopausal women: a systematic literature reviewarticlepublishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8805https://intellectum.unisabana.edu.co/bitstream/10818/36799/2/license_rdf4460e5956bc1d1639be9ae6146a50347MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-8498https://intellectum.unisabana.edu.co/bitstream/10818/36799/3/license.txtf52a2cfd4df262e08e9b300d62c85cabMD5310818/36799oai:intellectum.unisabana.edu.co:10818/367992022-05-10 05:18:59.297Intellectum Universidad de la Sabanacontactointellectum@unisabana.edu.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
dc.title.es_CO.fl_str_mv	The efficacy and safety of estriol to treat vulvovaginal atrophy in postmenopausal women: a systematic literature review
title	The efficacy and safety of estriol to treat vulvovaginal atrophy in postmenopausal women: a systematic literature review
spellingShingle	The efficacy and safety of estriol to treat vulvovaginal atrophy in postmenopausal women: a systematic literature review Estriol Vulvovaginal atrophy Systematic literature review
title_short	The efficacy and safety of estriol to treat vulvovaginal atrophy in postmenopausal women: a systematic literature review
title_full	The efficacy and safety of estriol to treat vulvovaginal atrophy in postmenopausal women: a systematic literature review
title_fullStr	The efficacy and safety of estriol to treat vulvovaginal atrophy in postmenopausal women: a systematic literature review
title_full_unstemmed	The efficacy and safety of estriol to treat vulvovaginal atrophy in postmenopausal women: a systematic literature review
title_sort	The efficacy and safety of estriol to treat vulvovaginal atrophy in postmenopausal women: a systematic literature review
dc.creator.fl_str_mv	Rueda, C. Osorio, A. M. Avellaneda, A. C. Pinzón Flórez, Carlos Eduardo Restrepo Castro, Olga Isabel
dc.contributor.author.none.fl_str_mv	Rueda, C. Osorio, A. M. Avellaneda, A. C. Pinzón Flórez, Carlos Eduardo Restrepo Castro, Olga Isabel
dc.subject.es_CO.fl_str_mv	Estriol Vulvovaginal atrophy Systematic literature review
topic	Estriol Vulvovaginal atrophy Systematic literature review
description	11 páginas
publishDate	2017
dc.date.issued.none.fl_str_mv	2017-06
dc.date.available.none.fl_str_mv	2019-08-23T14:27:17Z
dc.date.accessioned.none.fl_str_mv	8/23/2019 9:27
dc.type.en.fl_str_mv	article
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dc.identifier.citation.es_CO.fl_str_mv	C. Rueda, A. M. Osorio, A. C. Avellaneda, C. E. Pinzón & O. I. Restrepo (2017) The efficacy and safety of estriol to treat vulvovaginal atrophy in postmenopausal women: a systematic literature review, Climacteric, 20:4, 321-330, DOI: 10.1080/13697137.2017.1329291
dc.identifier.issn.none.fl_str_mv	1473-0804
dc.identifier.other.none.fl_str_mv	https://www.tandfonline.com/doi/full/10.1080/13697137.2017.1329291
dc.identifier.uri.none.fl_str_mv	http://hdl.handle.net/10818/36799
dc.identifier.doi.none.fl_str_mv	10.1080/13697137.2017.1329291
identifier_str_mv	C. Rueda, A. M. Osorio, A. C. Avellaneda, C. E. Pinzón & O. I. Restrepo (2017) The efficacy and safety of estriol to treat vulvovaginal atrophy in postmenopausal women: a systematic literature review, Climacteric, 20:4, 321-330, DOI: 10.1080/13697137.2017.1329291 1473-0804 10.1080/13697137.2017.1329291
url	https://www.tandfonline.com/doi/full/10.1080/13697137.2017.1329291 http://hdl.handle.net/10818/36799
dc.language.iso.es_CO.fl_str_mv	eng
language	eng
dc.relation.ispartofseries.none.fl_str_mv	Journal Climacteric 2017 V. 20, N. 4, 321–330
dc.rights.*.fl_str_mv	Attribution-NonCommercial-NoDerivatives 4.0 International
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dc.publisher.es_CO.fl_str_mv	Journal Climacteric
dc.source.es_CO.fl_str_mv	Universidad de La Sabana Intellectum Repositorio Universidad de La Sabana
institution	Universidad de la Sabana
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The efficacy and safety of estriol to treat vulvovaginal atrophy in postmenopausal women: a systematic literature review

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