Vitamin D-binding protein is inversely associated with the incidence of gastrointestinal and ear infections in school-age children
7 páginas
- Autores:
-
Palframan, K.M.
Robinson, S.L.
Mora Plazas, M.
Marin, C.
Villamor, E.
- Tipo de recurso:
- Fecha de publicación:
- 2018
- Institución:
- Universidad de la Sabana
- Repositorio:
- Repositorio Universidad de la Sabana
- Idioma:
- eng
- OAI Identifier:
- oai:intellectum.unisabana.edu.co:10818/37248
- Acceso en línea:
- https://www.cambridge.org/core/journals/epidemiology-and-infection/article/vitamin-dbinding-protein-is-inversely-associated-with-the-incidence-of-gastrointestinal-and-ear-infections-in-schoolage-children/0379AC8237F974C354C47E7312FA3BFA
https://www.cambridge.org/core/services/aop-cambridge-core/content/view/0379AC8237F974C354C47E7312FA3BFA/S0950268818002066a.pdf/vitamin_dbinding_protein_is_inversely_associated_with_the_incidence_of_gastrointestinal_and_ear_infections_in_schoolage_children.pdf
http://hdl.handle.net/10818/37248
- Palabra clave:
- Diarrhoea
Earache
Infection
Morbidity
Otitis
Vitamin D-binding protein
Vitamin D
- Rights
- License
- Attribution-NonCommercial-NoDerivatives 4.0 International
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| dc.title.es_CO.fl_str_mv |
Vitamin D-binding protein is inversely associated with the incidence of gastrointestinal and ear infections in school-age children |
| dc.title.alternative.en.fl_str_mv |
Vitamin D binding protein is inversely associated with the incidence of gastrointestinal and ear infections in school-age children |
| title |
Vitamin D-binding protein is inversely associated with the incidence of gastrointestinal and ear infections in school-age children |
| spellingShingle |
Vitamin D-binding protein is inversely associated with the incidence of gastrointestinal and ear infections in school-age children Diarrhoea Earache Infection Morbidity Otitis Vitamin D-binding protein Vitamin D |
| title_short |
Vitamin D-binding protein is inversely associated with the incidence of gastrointestinal and ear infections in school-age children |
| title_full |
Vitamin D-binding protein is inversely associated with the incidence of gastrointestinal and ear infections in school-age children |
| title_fullStr |
Vitamin D-binding protein is inversely associated with the incidence of gastrointestinal and ear infections in school-age children |
| title_full_unstemmed |
Vitamin D-binding protein is inversely associated with the incidence of gastrointestinal and ear infections in school-age children |
| title_sort |
Vitamin D-binding protein is inversely associated with the incidence of gastrointestinal and ear infections in school-age children |
| dc.creator.fl_str_mv |
Palframan, K.M. Robinson, S.L. Mora Plazas, M. Marin, C. Villamor, E. |
| dc.contributor.author.none.fl_str_mv |
Palframan, K.M. Robinson, S.L. Mora Plazas, M. Marin, C. Villamor, E. |
| dc.subject.es_CO.fl_str_mv |
Diarrhoea Earache Infection Morbidity Otitis Vitamin D-binding protein Vitamin D |
| topic |
Diarrhoea Earache Infection Morbidity Otitis Vitamin D-binding protein Vitamin D |
| description |
7 páginas |
| publishDate |
2018 |
| dc.date.issued.none.fl_str_mv |
2018-07-30 |
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2019-09-18T14:39:52Z |
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9/18/2019 9:39 |
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article |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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Palframan KM, Robinson SL, Mora-Plazas M, Marin C, Villamor E (2018). Vitamin D-binding protein is inversely associated with the incidence of gastrointestinal and ear infections in school-age children. Epidemiology and Infection 146, 1996–2002. https://doi.org/ 10.1017/S0950268818002066 |
| dc.identifier.issn.none.fl_str_mv |
1469-4409 |
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https://www.cambridge.org/core/journals/epidemiology-and-infection/article/vitamin-dbinding-protein-is-inversely-associated-with-the-incidence-of-gastrointestinal-and-ear-infections-in-schoolage-children/0379AC8237F974C354C47E7312FA3BFA https://www.cambridge.org/core/services/aop-cambridge-core/content/view/0379AC8237F974C354C47E7312FA3BFA/S0950268818002066a.pdf/vitamin_dbinding_protein_is_inversely_associated_with_the_incidence_of_gastrointestinal_and_ear_infections_in_schoolage_children.pdf |
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http://hdl.handle.net/10818/37248 |
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10.1017/S0950268818002066 |
| identifier_str_mv |
Palframan KM, Robinson SL, Mora-Plazas M, Marin C, Villamor E (2018). Vitamin D-binding protein is inversely associated with the incidence of gastrointestinal and ear infections in school-age children. Epidemiology and Infection 146, 1996–2002. https://doi.org/ 10.1017/S0950268818002066 1469-4409 10.1017/S0950268818002066 |
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https://www.cambridge.org/core/journals/epidemiology-and-infection/article/vitamin-dbinding-protein-is-inversely-associated-with-the-incidence-of-gastrointestinal-and-ear-infections-in-schoolage-children/0379AC8237F974C354C47E7312FA3BFA https://www.cambridge.org/core/services/aop-cambridge-core/content/view/0379AC8237F974C354C47E7312FA3BFA/S0950268818002066a.pdf/vitamin_dbinding_protein_is_inversely_associated_with_the_incidence_of_gastrointestinal_and_ear_infections_in_schoolage_children.pdf http://hdl.handle.net/10818/37248 |
| dc.language.iso.es_CO.fl_str_mv |
eng |
| language |
eng |
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Infection , Volume 146, Issue 15 p. 1996–2002 |
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Attribution-NonCommercial-NoDerivatives 4.0 International |
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application/pdf |
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Epidemiology and Infection |
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Universidad de La Sabana Intellectum Repositorio Universidad de La Sabana |
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Palframan, K.M.Robinson, S.L.Mora Plazas, M.Marin, C.Villamor, E.9/18/2019 9:392019-09-18T14:39:52Z2018-07-30Palframan KM, Robinson SL, Mora-Plazas M, Marin C, Villamor E (2018). Vitamin D-binding protein is inversely associated with the incidence of gastrointestinal and ear infections in school-age children. Epidemiology and Infection 146, 1996–2002. https://doi.org/ 10.1017/S09502688180020661469-4409https://www.cambridge.org/core/journals/epidemiology-and-infection/article/vitamin-dbinding-protein-is-inversely-associated-with-the-incidence-of-gastrointestinal-and-ear-infections-in-schoolage-children/0379AC8237F974C354C47E7312FA3BFAhttps://www.cambridge.org/core/services/aop-cambridge-core/content/view/0379AC8237F974C354C47E7312FA3BFA/S0950268818002066a.pdf/vitamin_dbinding_protein_is_inversely_associated_with_the_incidence_of_gastrointestinal_and_ear_infections_in_schoolage_children.pdfhttp://hdl.handle.net/10818/3724810.1017/S09502688180020667 páginasCirculating 25-hydroxy vitamin D (25(OH)D) is related to decreased rates of gastrointestinal and ear infections in school-age children. Vitamin D-binding protein (DBP) transports 25 (OH)D and exerts immunological functions; however, it is unknown whether DBP is associated with infectious morbidity in children. We quantified plasma DBP concentrations in 540 school-age children at the time of recruitment into a cohort study in Bogotá, Colombia and obtained daily information on infectious morbidity symptoms and doctor visits during the school year. We compared the incidence rates of gastrointestinal and respiratory symptoms across quartiles of DBP concentration by estimating adjusted incidence rate ratios (IRRs) with 95% confidence interval (CI). We also estimated the per cent of the associations between DBP and morbidity that were mediated through 25(OH)D using a counterfactual frame. Mean ± S.D. DBP concentration was 2650 ± 1145 nmol/l. DBP was inversely associated with the rates of diarrhoea with vomiting (IRR for quartiles 2–4 vs. 1 = 0.48; 95% CI 0.25–0.92; P = 0.03) and earache/ear discharge with fever (IRR for quartiles 2–4 vs. 1 = 0.29; 95% CI 0.12–0.71; P = 0.006). The DBP–morbidity associations were not mediated through 25(OH) D. We conclude that plasma DBP predicts lower incidence of gastrointestinal and ear infections in school-age children independent of 25(OH)D.application/pdfengEpidemiology and InfectionInfection , Volume 146, Issue 15 p. 1996–2002Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/http://purl.org/coar/access_right/c_abf2Universidad de La SabanaIntellectum Repositorio Universidad de La SabanaDiarrhoeaEaracheInfectionMorbidityOtitisVitamin D-binding proteinVitamin DVitamin D-binding protein is inversely associated with the incidence of gastrointestinal and ear infections in school-age childrenVitamin D binding protein is inversely associated with the incidence of gastrointestinal and ear infections in school-age childrenarticlepublishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501LICENSElicense.txtlicense.txttext/plain; charset=utf-8498https://intellectum.unisabana.edu.co/bitstream/10818/37248/3/license.txtf52a2cfd4df262e08e9b300d62c85cabMD53CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8805https://intellectum.unisabana.edu.co/bitstream/10818/37248/2/license_rdf4460e5956bc1d1639be9ae6146a50347MD5210818/37248oai:intellectum.unisabana.edu.co:10818/372482022-05-10 05:19:45.902Intellectum Universidad de la Sabanacontactointellectum@unisabana.edu.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 |