Regional citrate anticoagulation for continuous renal replacement therapy in children
9 páginas
- Autores:
-
Prada Rico, Mayerly
Fernández Sarmiento, Jaime
Rojas Velasquez, Ana María
González Chaparro, Luz Stella
Gastelbondo Amaya, Ricardo
Mulett Hoyos, Hernando
Tibaduiza, Daniel
Quintero Gómez, Ana Maria
- Tipo de recurso:
- Fecha de publicación:
- 2017
- Institución:
- Universidad de la Sabana
- Repositorio:
- Repositorio Universidad de la Sabana
- Idioma:
- eng
- OAI Identifier:
- oai:intellectum.unisabana.edu.co:10818/37145
- Acceso en línea:
- https://link.springer.com/article/10.1007%2Fs00467-016-3544-9#citeas
https://link.springer.com/content/pdf/10.1007%2Fs00467-016-3544-9.pdf
http://hdl.handle.net/10818/37145
- Palabra clave:
- Anticoagulation
Citrate
Heparin
Continuous renal replacement therapy
Dialysis
Children
- Rights
- License
- Attribution-NonCommercial-NoDerivatives 4.0 International
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Prada Rico, MayerlyFernández Sarmiento, JaimeRojas Velasquez, Ana MaríaGonzález Chaparro, Luz StellaGastelbondo Amaya, RicardoMulett Hoyos, HernandoTibaduiza, DanielQuintero Gómez, Ana Maria9/12/2019 10:502019-09-12T15:50:17Z2017Rico, M.P., Fernández Sarmiento, J., Rojas Velasquez, A.M. et al. Pediatr Nephrol (2017) 32: 703. https://doi.org/10.1007/s00467-016-3544-91432-198Xhttps://link.springer.com/article/10.1007%2Fs00467-016-3544-9#citeashttps://link.springer.com/content/pdf/10.1007%2Fs00467-016-3544-9.pdfhttp://hdl.handle.net/10818/3714510.1007/s00467-016-3544-99 páginasBackground Anticoagulation of the continuous renal replacement therapy (CRRT) circuit is an important technical aspect of this medical procedure. Most studies evaluating the efficacy and safety of citrate use have been carried out in adults, and little evidence is available for the pediatric patient population. The aim of this study was to compare regional citrate anticoagulation versus systemic heparin anticoagulation in terms of the lifetime of hemofilters in a pediatric population receiving CRRT at a pediatric center in Bogota, Colombia. Methods This was an analytical, observational, retrospective cohort study in which we assessed the survival of 150 hemofilters (citrate group 80 hemofilters, heparin group 70 hemofilters) used in a total of 3442 hours of CCRT (citrate group 2248 h, heparin group 1194 h). Hemofilter survival was estimated beginning at placement and continuing until filter replacement due to clotting or high trans-membrane pressures. Results Hemofilter survival was higher in the citrate group than in the heparin group (72 vs. 18 h; p <0.0001). Bivariate analysis showed that the hemofilter coagulation risk was significantly increased when heparin was used, regardless of hemofilter size and pump flow (hazard ratio 3.70, standard error 0.82, 95% confidence interval 2.39–5.72; p <0.00001). Conclusions Regional citrate anticoagulation could be more effective than heparin systemic anticoagulation in terms of prolonging the hemofilter lifetime in patients with acute renal injury who require CRRT.application/pdfengPediatric NephrologyPediatr Nephrol (2017) 32: 703Attribution-NonCommercial-NoDerivatives 4.0 Internationalhttp://creativecommons.org/licenses/by-nc-nd/4.0/http://purl.org/coar/access_right/c_abf2Universidad de La SabanaIntellectum Repositorio Universidad de La SabanaAnticoagulationCitrateHeparinContinuous renal replacement therapyDialysisChildrenRegional citrate anticoagulation for continuous renal replacement therapy in childrenarticlepublishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8805https://intellectum.unisabana.edu.co/bitstream/10818/37145/2/license_rdf4460e5956bc1d1639be9ae6146a50347MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-8498https://intellectum.unisabana.edu.co/bitstream/10818/37145/3/license.txtf52a2cfd4df262e08e9b300d62c85cabMD5310818/37145oai:intellectum.unisabana.edu.co:10818/371452022-05-10 05:19:48.215Intellectum Universidad de la Sabanacontactointellectum@unisabana.edu.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 |
| dc.title.es_CO.fl_str_mv |
Regional citrate anticoagulation for continuous renal replacement therapy in children |
| title |
Regional citrate anticoagulation for continuous renal replacement therapy in children |
| spellingShingle |
Regional citrate anticoagulation for continuous renal replacement therapy in children Anticoagulation Citrate Heparin Continuous renal replacement therapy Dialysis Children |
| title_short |
Regional citrate anticoagulation for continuous renal replacement therapy in children |
| title_full |
Regional citrate anticoagulation for continuous renal replacement therapy in children |
| title_fullStr |
Regional citrate anticoagulation for continuous renal replacement therapy in children |
| title_full_unstemmed |
Regional citrate anticoagulation for continuous renal replacement therapy in children |
| title_sort |
Regional citrate anticoagulation for continuous renal replacement therapy in children |
| dc.creator.fl_str_mv |
Prada Rico, Mayerly Fernández Sarmiento, Jaime Rojas Velasquez, Ana María González Chaparro, Luz Stella Gastelbondo Amaya, Ricardo Mulett Hoyos, Hernando Tibaduiza, Daniel Quintero Gómez, Ana Maria |
| dc.contributor.author.none.fl_str_mv |
Prada Rico, Mayerly Fernández Sarmiento, Jaime Rojas Velasquez, Ana María González Chaparro, Luz Stella Gastelbondo Amaya, Ricardo Mulett Hoyos, Hernando Tibaduiza, Daniel Quintero Gómez, Ana Maria |
| dc.subject.es_CO.fl_str_mv |
Anticoagulation Citrate Heparin Continuous renal replacement therapy Dialysis Children |
| topic |
Anticoagulation Citrate Heparin Continuous renal replacement therapy Dialysis Children |
| description |
9 páginas |
| publishDate |
2017 |
| dc.date.issued.none.fl_str_mv |
2017 |
| dc.date.available.none.fl_str_mv |
2019-09-12T15:50:17Z |
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9/12/2019 10:50 |
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article |
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Rico, M.P., Fernández Sarmiento, J., Rojas Velasquez, A.M. et al. Pediatr Nephrol (2017) 32: 703. https://doi.org/10.1007/s00467-016-3544-9 |
| dc.identifier.issn.none.fl_str_mv |
1432-198X |
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https://link.springer.com/article/10.1007%2Fs00467-016-3544-9#citeas https://link.springer.com/content/pdf/10.1007%2Fs00467-016-3544-9.pdf |
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http://hdl.handle.net/10818/37145 |
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10.1007/s00467-016-3544-9 |
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Rico, M.P., Fernández Sarmiento, J., Rojas Velasquez, A.M. et al. Pediatr Nephrol (2017) 32: 703. https://doi.org/10.1007/s00467-016-3544-9 1432-198X 10.1007/s00467-016-3544-9 |
| url |
https://link.springer.com/article/10.1007%2Fs00467-016-3544-9#citeas https://link.springer.com/content/pdf/10.1007%2Fs00467-016-3544-9.pdf http://hdl.handle.net/10818/37145 |
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eng |
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eng |
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Pediatr Nephrol (2017) 32: 703 |
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Attribution-NonCommercial-NoDerivatives 4.0 International |
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http://creativecommons.org/licenses/by-nc-nd/4.0/ |
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Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ http://purl.org/coar/access_right/c_abf2 |
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Pediatric Nephrology |
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Universidad de La Sabana Intellectum Repositorio Universidad de La Sabana |
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Universidad de la Sabana |
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