Optical Biosensors for Therapeutic Drug Monitoring

26 páginas

Autores:: Garzón, Vivian
Pinacho, Daniel G.
Bustos, Rosa-Helena
Garzón, Gustavo
Bustamante, Sandra

Tipo de recurso:

Fecha de publicación:: 2019

Institución:: Universidad de la Sabana

Repositorio:: Repositorio Universidad de la Sabana

Idioma:: eng

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spelling	Garzón, VivianPinacho, Daniel G.Bustos, Rosa-HelenaGarzón, GustavoBustamante, Sandra8/31/2021 11:472021-08-31T16:47:11Z2019-11-11Garzón, V., Pinacho, D., Bustos, R.H., Garzón, G. & Bustamante, S. (2019). Optical Biosensors for Therapeutic Drug Monitoring. Biosensors 9(132), 1-26.2079-6374https://www.mdpi.com/2079-6374/9/4/132/htmhttp://hdl.handle.net/10818/4822310.3390/bios904013226 páginasTherapeutic drug monitoring (TDM) is a fundamental tool when administering drugs that have a limited dosage or high toxicity, which could endanger the lives of patients. To carry out this monitoring, one can use different biological fluids, including blood, plasma, serum, and urine, among others. The help of specialized methodologies for TDM will allow for the pharmacodynamic and pharmacokinetic analysis of drugs and help adjust the dose before or during their administration. Techniques that are more versatile and label free for the rapid quantification of drugs employ biosensors, devices that consist of one element for biological recognition coupled to a signal transducer. Among biosensors are those of the optical biosensor type, which have been used for the quantification of different molecules of clinical interest, such as antibiotics, anticonvulsants, anti-cancer drugs, and heart failure. This review presents an overview of TDM at the global level considering various aspects and clinical applications. In addition, we review the contributions of optical biosensors to TDM.application/pdfengBiosensorsBiosensors 2019, 9(4), 132Attribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/http://purl.org/coar/access_right/c_abf2Universidad de La SabanaIntellectum Repositorio Universidad de La SabanaTherapeutic drug monitoring (TDM)NanobiosensorsOptical biosensorsPharmacologyPersonalized medicineOptical Biosensors for Therapeutic Drug MonitoringarticlepublishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501CC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8805https://intellectum.unisabana.edu.co/bitstream/10818/48223/2/license_rdf4460e5956bc1d1639be9ae6146a50347MD52LICENSElicense.txtlicense.txttext/plain; charset=utf-8498https://intellectum.unisabana.edu.co/bitstream/10818/48223/3/license.txtf52a2cfd4df262e08e9b300d62c85cabMD5310818/48223oai:intellectum.unisabana.edu.co:10818/482232022-05-10 05:22:01.157Intellectum Universidad de la Sabanacontactointellectum@unisabana.edu.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
dc.title.es_CO.fl_str_mv	Optical Biosensors for Therapeutic Drug Monitoring
title	Optical Biosensors for Therapeutic Drug Monitoring
spellingShingle	Optical Biosensors for Therapeutic Drug Monitoring Therapeutic drug monitoring (TDM) Nanobiosensors Optical biosensors Pharmacology Personalized medicine
title_short	Optical Biosensors for Therapeutic Drug Monitoring
title_full	Optical Biosensors for Therapeutic Drug Monitoring
title_fullStr	Optical Biosensors for Therapeutic Drug Monitoring
title_full_unstemmed	Optical Biosensors for Therapeutic Drug Monitoring
title_sort	Optical Biosensors for Therapeutic Drug Monitoring
dc.creator.fl_str_mv	Garzón, Vivian Pinacho, Daniel G. Bustos, Rosa-Helena Garzón, Gustavo Bustamante, Sandra
dc.contributor.author.none.fl_str_mv	Garzón, Vivian Pinacho, Daniel G. Bustos, Rosa-Helena Garzón, Gustavo Bustamante, Sandra
dc.subject.other.en.fl_str_mv	Therapeutic drug monitoring (TDM) Nanobiosensors Optical biosensors Pharmacology Personalized medicine
topic	Therapeutic drug monitoring (TDM) Nanobiosensors Optical biosensors Pharmacology Personalized medicine
description	26 páginas
publishDate	2019
dc.date.issued.none.fl_str_mv	2019-11-11
dc.date.available.none.fl_str_mv	2021-08-31T16:47:11Z
dc.date.accessioned.none.fl_str_mv	8/31/2021 11:47
dc.type.en.fl_str_mv	article
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dc.type.hasVersion.es_CO.fl_str_mv	publishedVersion
dc.identifier.citation.es_CO.fl_str_mv	Garzón, V., Pinacho, D., Bustos, R.H., Garzón, G. & Bustamante, S. (2019). Optical Biosensors for Therapeutic Drug Monitoring. Biosensors 9(132), 1-26.
dc.identifier.issn.none.fl_str_mv	2079-6374
dc.identifier.other.none.fl_str_mv	https://www.mdpi.com/2079-6374/9/4/132/htm
dc.identifier.uri.none.fl_str_mv	http://hdl.handle.net/10818/48223
dc.identifier.doi.none.fl_str_mv	10.3390/bios9040132
identifier_str_mv	Garzón, V., Pinacho, D., Bustos, R.H., Garzón, G. & Bustamante, S. (2019). Optical Biosensors for Therapeutic Drug Monitoring. Biosensors 9(132), 1-26. 2079-6374 10.3390/bios9040132
url	https://www.mdpi.com/2079-6374/9/4/132/htm http://hdl.handle.net/10818/48223
dc.language.iso.es_CO.fl_str_mv	eng
language	eng
dc.relation.ispartofseries.none.fl_str_mv	Biosensors 2019, 9(4), 132
dc.rights.*.fl_str_mv	Attribution-NonCommercial-NoDerivatives 4.0 Internacional
dc.rights.coar.fl_str_mv	http://purl.org/coar/access_right/c_abf2
dc.rights.uri.*.fl_str_mv	http://creativecommons.org/licenses/by-nc-nd/4.0/
rights_invalid_str_mv	Attribution-NonCommercial-NoDerivatives 4.0 Internacional http://creativecommons.org/licenses/by-nc-nd/4.0/ http://purl.org/coar/access_right/c_abf2
dc.format.es_CO.fl_str_mv	application/pdf
dc.publisher.es_CO.fl_str_mv	Biosensors
dc.source.es_CO.fl_str_mv	Universidad de La Sabana Intellectum Repositorio Universidad de La Sabana
institution	Universidad de la Sabana
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Optical Biosensors for Therapeutic Drug Monitoring

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