Scoping review on population pharmacokinetics of vancomy- 2 cin in hospitalized adults
14 páginas
- Autores:
-
Vivas Suarez, Juan David
Nivia Fonseca, Diego Armando
Briceño, Wilson
Parra, Daniel
Jaimes, Diego
- Tipo de recurso:
- Trabajo de grado de pregrado
- Fecha de publicación:
- 2022
- Institución:
- Universidad de la Sabana
- Repositorio:
- Repositorio Universidad de la Sabana
- Idioma:
- eng
- OAI Identifier:
- oai:intellectum.unisabana.edu.co:10818/51536
- Acceso en línea:
- https://hdl.handle.net/10818/51536
- Palabra clave:
- Hospitalizados
Farmacocinética
Medicamentos -- Efectos fisiológicos
- Rights
- License
- Attribution-NonCommercial-NoDerivatives 4.0 Internacional
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Scoping review on population pharmacokinetics of vancomy- 2 cin in hospitalized adults |
| title |
Scoping review on population pharmacokinetics of vancomy- 2 cin in hospitalized adults |
| spellingShingle |
Scoping review on population pharmacokinetics of vancomy- 2 cin in hospitalized adults Hospitalizados Farmacocinética Medicamentos -- Efectos fisiológicos |
| title_short |
Scoping review on population pharmacokinetics of vancomy- 2 cin in hospitalized adults |
| title_full |
Scoping review on population pharmacokinetics of vancomy- 2 cin in hospitalized adults |
| title_fullStr |
Scoping review on population pharmacokinetics of vancomy- 2 cin in hospitalized adults |
| title_full_unstemmed |
Scoping review on population pharmacokinetics of vancomy- 2 cin in hospitalized adults |
| title_sort |
Scoping review on population pharmacokinetics of vancomy- 2 cin in hospitalized adults |
| dc.creator.fl_str_mv |
Vivas Suarez, Juan David Nivia Fonseca, Diego Armando Briceño, Wilson Parra, Daniel Jaimes, Diego |
| dc.contributor.advisor.none.fl_str_mv |
Bustos Cruz, Rosa Helena |
| dc.contributor.author.none.fl_str_mv |
Vivas Suarez, Juan David Nivia Fonseca, Diego Armando Briceño, Wilson Parra, Daniel Jaimes, Diego |
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Hospitalizados |
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Hospitalizados Farmacocinética Medicamentos -- Efectos fisiológicos |
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Farmacocinética Medicamentos -- Efectos fisiológicos |
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14 páginas |
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2022 |
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2022-08-29T16:14:51Z |
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2022-08-29T16:14:51Z |
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2022-04-28 |
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286896 TE11832 |
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eng |
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Universidad de La Sabana |
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Bustos Cruz, Rosa HelenaVivas Suarez, Juan DavidNivia Fonseca, Diego ArmandoBriceño, WilsonParra, DanielJaimes, Diego2022-08-29T16:14:51Z2022-08-29T16:14:51Z2022-04-28https://hdl.handle.net/10818/51536286896TE1183214 páginasVancomycin is an effective first-line therapy in MRSA infection, however, achieving an 13 appropriate serum concentration is challenging. Population pharmacokinetics can offer assistance 14 to the clinician in the selection of better regimen dosing and improve effectiveness and safety out- 15 comes. This scoping review aims to outline the evidence in population pharmacokinetic models in 16 non-critical adults hospitalized from 1980 to 2021 and describe the principal software and covaria- 17 bles used in this. A total of 209 papers were fully screened. Finally, we included 17 articles con- 18 ducted in different locations around the world. This review identified 13 retrospective articles and 19 4 prospective, 5 describing the use in a general population with gram-positive bacterial infection, 20 11 evaluated special populations (older, obese, and cancer patients), and 1 mixed population. The 21 main parameters in the models were renal clearance and volume of distribution. The principal co- 22 variables that affected the models were creatinine clearance and weight. All studies use internal 23 validation methods, and three of them used an external validation group. This scoping review high- 24 lights the principal information of different population pharmacokinetic models and the heteroge- 25 neity in the parameters and methods of evaluation. These methods can be used to guide the dosing 26 regimen in different subpopulations. However, it is imperative to define the best fit in every popu- 27 lation and conduct an experiment due to the high variability in the present studies.application/pdfengUniversidad de La SabanaAttribution-NonCommercial-NoDerivatives 4.0 Internacionalhttp://creativecommons.org/licenses/by-nc-nd/4.0/http://purl.org/coar/access_right/c_abf2Universidad de La SabanaIntellectum Repositorio Universidad de La SabanaHospitalizadosFarmacocinéticaMedicamentos -- Efectos fisiológicosScoping review on population pharmacokinetics of vancomy- 2 cin in hospitalized adultsTesis/Trabajo de grado - Especializaciónhttp://purl.org/coar/resource_type/c_7a1fTextoinfo:eu-repo/semantics/otherhttp://purl.org/redcol/resource_type/COtherinfo:eu-repo/semantics/acceptedVersionFacultad de MedicinaEspecialización en Farmacología ClínicaEspecialista en Farmacología ClínicaPublicationORIGINALFormato de autorizacion de divulgacion RI trabajos de grado V2bk - signed (1).pdfFormato de autorizacion de divulgacion RI trabajos de grado V2bk - signed (1).pdfVer documento en PDFapplication/pdf695505https://intellectum.unisabana.edu.co/bitstreams/447b285c-3452-4a22-9798-0f3fa9538180/downloadfa55ead0ea292a6cdc5c0e569fa23ce1MD51trueAnonymousREADTEXTFormato de autorizacion de divulgacion RI trabajos de grado V2bk - signed (1).pdf.txtFormato de autorizacion de divulgacion RI trabajos de grado V2bk - signed (1).pdf.txtExtracted texttext/plain7843https://intellectum.unisabana.edu.co/bitstreams/9338dd18-21d4-4307-8613-5fee646b319b/download20c30c3343e04bbf72765b5cbc9a2022MD54falseAnonymousREADCC-LICENSElicense_rdflicense_rdfapplication/rdf+xml; charset=utf-8805https://intellectum.unisabana.edu.co/bitstreams/dded3b90-6855-442c-a57a-30b4fb9daf7d/download4460e5956bc1d1639be9ae6146a50347MD52falseAnonymousREADLICENSElicense.txtlicense.txttext/plain; charset=utf-8498https://intellectum.unisabana.edu.co/bitstreams/016583d1-1e4f-4bc7-b648-9c5854348b37/downloadf52a2cfd4df262e08e9b300d62c85cabMD53falseAnonymousREADTHUMBNAILFormato de autorizacion de divulgacion RI trabajos de grado V2bk - signed (1).pdf.jpgFormato de autorizacion de divulgacion RI trabajos de grado V2bk - signed (1).pdf.jpgGenerated Thumbnailimage/jpeg15128https://intellectum.unisabana.edu.co/bitstreams/56091068-797f-4d3d-a78e-7c5ce8df44b2/download908bb40ed38237f030d73238f9f880d8MD55falseAnonymousREAD10818/51536oai:intellectum.unisabana.edu.co:10818/515362025-12-11 13:44:13.997http://creativecommons.org/licenses/by-nc-nd/4.0/Attribution-NonCommercial-NoDerivatives 4.0 Internacionalopen.accesshttps://intellectum.unisabana.edu.coIntellectum Repositorio Universidad de La Sabanacontactointellectum@unisabana.edu.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 |