Diagnosis of canine monocytotropic ehrlichiosis: an update review

Canine monocytic ehrlichiosis (CME) is caused by the infection with a rickettsial organism, Ehrlichia canis. This organism is replicated only in the cytoplasm of blood monocytes and tissue macrophages. CME has been reported throughout the world but at higher frequencies in tropical and subtropical r...

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Autores:
Tipo de recurso:
Fecha de publicación:
2015
Institución:
Universidad Pedagógica y Tecnológica de Colombia
Repositorio:
RiUPTC: Repositorio Institucional UPTC
Idioma:
spa
OAI Identifier:
oai:repositorio.uptc.edu.co:001/10547
Acceso en línea:
https://revistas.uptc.edu.co/index.php/ciencia_agricultura/article/view/4126
https://repositorio.uptc.edu.co/handle/001/10547
Palabra clave:
ehrlichia canis
dogs diseases
thrombocytopenia
molecular diagnostic techniques
Inmuneadsortion Enzimatic test.
Ehrlichia canis
Enfermedades caninas
Trombocitopenia
Diagnóstico molecular
Ensayo de Inmunoadsorción Enzimática
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Copyright (c) 2016 CIENCIA Y AGRICULTURA
Description
Summary:Canine monocytic ehrlichiosis (CME) is caused by the infection with a rickettsial organism, Ehrlichia canis. This organism is replicated only in the cytoplasm of blood monocytes and tissue macrophages. CME has been reported throughout the world but at higher frequencies in tropical and subtropical regions. CME is often under-recognized since the disease is difficult to diagnose due to variable clinical signs, its different stages, and frequent co—infection with other tick-borne pathogens or other infectious agents. Clinical manifestations and the traditional diagnostic techniques such as hematology and demonstration of typical cytoplasmic E. canis-morulae in monocytes in blood smears have been used for the diagnosis of CME; however, the PCR—based diagnostic tests and serology methods based on specific antigens, are the most sensitive and specific for this disease. This article reviews the current literature covering the diagnosis of infection by E. canis in dogs.