Seroprevalencia de Fasciola hepatica en pequeños rumiantes de Boavita, Boyacá
Spa: La Fascioliasis, causada por Fasciola hepatica, afecta globalmente al ganado. Técnicas de diagnóstico tradicionales tienen limitaciones, retrasando la detección. Enfoques inmunológicos como ELISA mejoran la sensibilidad. Una investigación en Boavita, Boyacá, encontró una seroprevalencia del 72....
- Autores:
-
Ortiz Pineda, Melissa Camila
- Tipo de recurso:
- Trabajo de grado de pregrado
- Fecha de publicación:
- 2022
- Institución:
- Universidad Pedagógica y Tecnológica de Colombia
- Repositorio:
- RiUPTC: Repositorio Institucional UPTC
- Idioma:
- spa
- OAI Identifier:
- oai:repositorio.uptc.edu.co:001/9611
- Acceso en línea:
- https://repositorio.uptc.edu.co//handle/001/9611
- Palabra clave:
- Fasciola hepática
Ovejas - Enfermedades
Cabras - Enfermedades
Veterinarios - Aprendizaje experiencial
Veterinarios - Formación profesional
Ganado lanar
Rumiantes
Bóvidos
- Rights
- openAccess
- License
- Copyright (c) 2022 Universidad Pedagógica y Tecnológica de Colombia
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dc.title.en_US.fl_str_mv |
Seroprevalencia de Fasciola hepatica en pequeños rumiantes de Boavita, Boyacá |
title |
Seroprevalencia de Fasciola hepatica en pequeños rumiantes de Boavita, Boyacá |
spellingShingle |
Seroprevalencia de Fasciola hepatica en pequeños rumiantes de Boavita, Boyacá Fasciola hepática Ovejas - Enfermedades Cabras - Enfermedades Veterinarios - Aprendizaje experiencial Veterinarios - Formación profesional Ganado lanar Rumiantes Bóvidos |
title_short |
Seroprevalencia de Fasciola hepatica en pequeños rumiantes de Boavita, Boyacá |
title_full |
Seroprevalencia de Fasciola hepatica en pequeños rumiantes de Boavita, Boyacá |
title_fullStr |
Seroprevalencia de Fasciola hepatica en pequeños rumiantes de Boavita, Boyacá |
title_full_unstemmed |
Seroprevalencia de Fasciola hepatica en pequeños rumiantes de Boavita, Boyacá |
title_sort |
Seroprevalencia de Fasciola hepatica en pequeños rumiantes de Boavita, Boyacá |
dc.creator.fl_str_mv |
Ortiz Pineda, Melissa Camila |
dc.contributor.advisor.none.fl_str_mv |
García Corredor, Diego José |
dc.contributor.author.none.fl_str_mv |
Ortiz Pineda, Melissa Camila |
dc.subject.armarc.en_US.fl_str_mv |
Fasciola hepática Ovejas - Enfermedades Cabras - Enfermedades Veterinarios - Aprendizaje experiencial Veterinarios - Formación profesional |
topic |
Fasciola hepática Ovejas - Enfermedades Cabras - Enfermedades Veterinarios - Aprendizaje experiencial Veterinarios - Formación profesional Ganado lanar Rumiantes Bóvidos |
dc.subject.armarc.spa.fl_str_mv |
Ganado lanar Rumiantes Bóvidos |
description |
Spa: La Fascioliasis, causada por Fasciola hepatica, afecta globalmente al ganado. Técnicas de diagnóstico tradicionales tienen limitaciones, retrasando la detección. Enfoques inmunológicos como ELISA mejoran la sensibilidad. Una investigación en Boavita, Boyacá, encontró una seroprevalencia del 72.96%, mayor en ovinos (84.62%) que en caprinos (70.40%). Razas como Alpina y Nubiana en caprinos, y Camura en ovinos, mostraron asociación estadística con la seropositividad. La presencia de caracoles está vinculada a la enfermedad. Este conocimiento epidemiológico informa sobre la dinámica de transmisión y guía estrategias de manejo y control. |
publishDate |
2022 |
dc.date.issued.none.fl_str_mv |
2022 |
dc.date.accessioned.none.fl_str_mv |
2024-03-09T22:54:48Z |
dc.date.available.none.fl_str_mv |
2024-03-09T22:54:48Z |
dc.type.en_US.fl_str_mv |
Trabajo de grado pregrados |
dc.type.coar.en_US.fl_str_mv |
http://purl.org/coar/resource_type/c_7a1f |
dc.type.driver.en_US.fl_str_mv |
info:eu-repo/semantics/bachelorThesis |
dc.type.version.en_US.fl_str_mv |
info:eu-repo/semantics/publishedVersion |
dc.type.content.en_US.fl_str_mv |
Text |
dc.type.redcol.en_US.fl_str_mv |
https://purl.org/redcol/resource_type/TP |
dc.type.coarversion.en_US.fl_str_mv |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
format |
http://purl.org/coar/resource_type/c_7a1f |
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publishedVersion |
dc.identifier.citation.en_US.fl_str_mv |
Ortiz Pineda, M. C. (2022). Seroprevalencia de fasciola hepatica en pequeños rumiantes de Boavita, Boyacá. (Trabajo de pregrao). Universidad Pedagógica y Tecnológica de Colombia. Facultad de Ciencias Agropecuarias, Tunja. https://repositorio.uptc.edu.co//handle/001/9611 |
dc.identifier.uri.none.fl_str_mv |
https://repositorio.uptc.edu.co//handle/001/9611 |
identifier_str_mv |
Ortiz Pineda, M. C. (2022). Seroprevalencia de fasciola hepatica en pequeños rumiantes de Boavita, Boyacá. (Trabajo de pregrao). Universidad Pedagógica y Tecnológica de Colombia. Facultad de Ciencias Agropecuarias, Tunja. https://repositorio.uptc.edu.co//handle/001/9611 |
url |
https://repositorio.uptc.edu.co//handle/001/9611 |
dc.language.iso.fl_str_mv |
spa |
language |
spa |
dc.relation.references.en_US.fl_str_mv |
Abunna, F., Asfaw, L., Megersa, B., & Regassa, A. (2010). Bovine fasciolosis: Coprological, abattoir survey and its economic impact due to liver condemnation at Soddo municipal abattoir, Southern Ethiopia. Tropical Animal Health and Production, 42(2), 289–292. https://doi.org/10.1007/s11250-009-9419-3 Acevedo-Charry, O., Murillo-Bedoya, D., Buitrago-Cardona, A., Ospina-L, A. M., Medina-Uribe, C. A., Colón-Piñeiro, Z., Gómez-Valencia, B., Herrera-Varón, Y., & Ochoa-Quintero, J. M. (2021). Passive acoustic sampling data of the Colección de Sonidos Ambientales Mauricio Álvarez-Rebolledo - Instituto Humboldt (IAvH-CSA) during 2018 and 2019 in Colombia. Data in Brief, 34. https://doi.org/10.1016/j.dib.2020.106648 Addy, F., Gyan, K., Arhin, E., & Wassermann, M. (2020). Prevalence of bovine fasciolosis from the Bolgatanga abattoir, Ghana. Scientific African, 8. https://doi.org/10.1016/j.sciaf.2020.e00469 Ahmad, T., Imran, M., Ahmad, K., Khan, M., Baig, M., Al-Rifai, R. H., & Al-Omari, B. (2021). A Bibliometric Analysis and Global Trends in Fascioliasis Research: A Neglected Tropical Disease. Animals, 11(12), 3385. https://doi.org/10.3390/ani11123385 Alcaldía de Boavita. (7 de septiembre del 2022). Municipio de Boavita.http://www.boavita-boyaca.gov.co/ Alemneh, T. (2019). An Introductory to Fasciolosis. Concepts of Dairy & Veterinary Sciences, 2(3). https://doi.org/10.32474/cdvs.2019.02.000139 Alstedt, U., Voigt, K., Jäger, M. C., Knubben-Schweizer, G., Zablotski, Y., Strube, C., & Wenzel, C. (2022). Rumen and Liver Fluke Infections in Sheep and Goats in Northern and Southern Germany. Animals, 12(7). https://doi.org/10.3390/ani12070876 Alvarez, C. A., Jex, A. R., Gasser, R. B., & Scheerlinck, J. P. Y. (2014). Techniques for the Diagnosis of Fasciola Infections in Animals. Room for Improvement. In Advances in Parasitology (Vol. 85, pp. 65–107). Academic Press. https://doi.org/10.1016/B978-0-12-800182-0.00002-7 Amina K, N., Ouchene, N., & Dahmani, A. (2018). Fasciolosis due to Fasciola hepatica in ruminants in abattoirs and its economic impact in two regions in Algeria. https://www.researchgate.net/publication/324769609 Anjum, R., Khan, M. N., Sajid, M. S., & Javed, M. T. (2014). Frequency distribution of fasciolosis in small ruminants population at district Sargodha. Global Veterinaria, 12(1), 26–32. https://doi.org/10.5829/idosi.gv.2014.12.01.81152 Arenal, A., García, Y., Quesada, L., Velázquez, D., Sánchez, D., Peña, M., Suárez, A., Díaz, A., Sánchez, Y., Casaert, S., van Dijk, J., Vercruysse, J., & Charlier, J. (2018). Risk factors for the presence of Fasciola hepatica antibodies in bulk-milk samples and their association with milk production decreases, in Cuban dairy cattle. BMC Veterinary Research, 14(1). https://doi.org/10.1186/s12917-018-1654-2 Arias-Pacheco, C., Lucas, J. R., Rodríguez, A., Córdoba, D., & Lux-Hoppe, E. G. (2020). Economic impact of the liver condemnation of cattle infected with Fasciola hepatica in the Peruvian Andes. Tropical Animal Health and Production, 52(4), 1927–1932. https://doi.org/10.1007/s11250-020-02211-y Badirzadeh, A., & Sabzevari, S. (2017). Hepatic fascioliasis in Mashhad, Northeast Iran: First report. Revista Da Sociedade Brasileira de Medicina Tropical, 50(4), 571–574. https://doi.org/10.1590/0037-8682-0526-2016 Barreto, T., Alfonso, Y., Lafaye, P., García Lázaro, M. del P., Pérez, L. A., Herrera-Velit, P., & Espinoza, J. R. (2018). Single-chain antibodies from alpaca for the detection of Fasciola hepatica antigens. Revista Peruana de Medicina Experimental y Salud Publica, 35(4), 573–580. https://doi.org/10.17843/rpmesp.2018.354.3101 Becerra Rozo, W. (2001). Consideraciones sobre estrategias sostenibles para el control de Fasciola hepática en Latinoamérica. In Rev Col Cienc Pec. 14(1). Biruk Alemu Basore. (2019). Bovine Fasciolosis in Ethiopia-A review Journal of Veterinary and Animal Research Bovine Fasciolosis in Ethiopia-A review. Journal of Veterinary and Animal Research, 2(2), 1–12. www.scholarena.com Bolaños, R. (2021). Trematodes: una revisión a la importancia de Fasciola hepatica. In Revista Veterinaria ISSN. 32(2). www.vet.unne.edu.ar Bozorgomid, A., Rouhani, S., Harandi, M. F., Ichikawa-Seki, M., & Raeghi, S. (2020). Genetic diversity and distribution of Fasciola hepatica haplotypes in Iran: Molecular and phylogenetic studies. Veterinary Parasitology: Regional Studies and Reports, 19. https://doi.org/10.1016/j.vprsr.2019.100359 Calvani, N. E. D., George, S. D., Windsor, P. A., Bush, R. D., & Šlapeta, J. (2018). Comparison of early detection of Fasciola hepatica in experimentally infected Merino sheep by real-time PCR, coproantigen ELISA and sedimentation. Veterinary Parasitology, 251, 85–89. https://doi.org/10.1016/j.vetpar.2018.01.004 Calvani, N. E. D., & Šlapeta, J. (2021). Fasciola Species Introgression: Just a Fluke or Something More? In Trends in Parasitology. 7(1): 25–34. https://doi.org/10.1016/j.pt.2020.09.008 Caravedo, M. A., & Cabada, M. (2020). Human Fascioliasis: Current Epidemiological Status and Strategies for Diagnosis, Treatment, and Control. Research and Reports in Tropical Medicine, Volume 11, 149–158. https://doi.org/10.2147/rrtm.s237461 Carmona, C., & Tort, J. F. (2017). Fasciolosis in South America: epidemiology and control challenges. Journal of Helminthology, 91(2), 99–109. https://doi.org/10.1017/S0022149X16000560 elik, ., Aslan el k, B. (n.d.). Investigation of the Prevalence of Fasciola hepatica in Small Ruminants in the Siirt Region, Turkey (Vol. 13, Issue 4). http://ijpa.tums.ac.ir Celi-Erazo, M., Alda, P., Montenegro-Franco, M., Pavon, D., Minda-Aluisa, E., Calvopiña, M., Pointier, J. P., Hurtrez-Boussès, S., Cevallos, W., Benítez-Ortíz, W., & Rodríguez-Hidalgo, R. (2020). Prevalence of Fasciola hepatica infection in Galba cousini and Galba schirazensis from an Andean region of Ecuador. Veterinary Parasitology: Regional Studies and Reports, 20. https://doi.org/10.1016/j.vprsr.2020.100390 Charlier, J., Rinaldi, L., Musella, V., Ploeger, H. W., Chartier, C., Vineer, H. R., Hinney, B., von Samson-Himmelstjerna, G., Băcescu, B., Mickiewicz, M., Mateus, T. L., Martinez-Valladares, M., Quealy, S., Azaizeh, H., Sekovska, B., Akkari, H., Petkevicius, S., Hektoen, L., Höglund, J., … Claerebout, E. (2020). Initial assessment of the economic burden of major parasitic helminth infections to the ruminant livestock industry in Europe. Preventive Veterinary Medicine, 182. https://doi.org/10.1016/j.prevetmed.2020.105103 Científico, A., Pinzón, G., Pérez, E., Pinzón, E. G., Cárdenas, J. P., Marín, S. A., & Linares Villalba, S. (2016). Prevalence of bovine Fasciolosis in a zone of caldas Colombia with evidences of the disease. www.ucaldas.edu.co Clavijo, T. N. A. (2016). Caracterización de la agrocadena ovino-caprina en el municipio de Suesca vereda Tausaquira (Cundinamarca). https://ciencia.lasalle.edu.co/administracion_agronegocios. Colmenares, C., Méndez, L., Díaz-Bello, Z., Alarcón de Noya, B. (2007). Antígeno excreción-secreción de Fasciola hepatica: ultrafiltración y aplicación en inmunodiagnóstico. Acta Bioquímica Clínica Latinoamericana, 41 (2),259-266. Como, Zambrano, M. M., Medina, P. M., Pozo Muñoz, D. J., Andrade, S. C., Franco Diagnóstico, H. A., Elena Muñoz Zambrano, M., Placencia Medina, M., Andree Del Pozo Muñoz, J., Sevilla Andrade, C., & Huiza Franco, A. (2020). Serological diagnosis of Fasciola hepatica infection: a systematic review. In Rev Gastroenterol Peru (Vol. 40, Issue 2). Cornejo, H., Oblitas, fátima, & Cruzado, S. (2010). Evaluación de una prueba de Elisa con antígeno metabólico de Fasciola hepatica para el diagnóstico de Fasciolosis humana en cajamarca, perú. In Rev Peru Med Exp Salud Publica. 27(4). Corrales, Y., Ferrer, E., Fernández, J., Gauta, J., García, M., Aguirre, A., & Pérez, A. (2021). Diagnosis and Risk Factors of Bovine and Human Fascioliasis in Cattle Farms from a Venezuelan Andean Rural Area. Acta Parasitologica, 66(3), 1048–1054. https://doi.org/10.1007/s11686-021-00341-3 Corral-Ruiz, G. M., & Sánchez-Torres, L. E. (2020). Fasciola hepatica-derived molecules as potential immunomodulators. Acta Tropica. 210. https://doi.org/10.1016/j.actatropica.2020.105548 Correa, S., Martínez, Y. L., López, J. L., & Velásquez, L. E. (2016). Evaluación de la técnica modificada de Dennis para el diagnóstico de fasciolosis bovina. Biomedica, 36, 64–68. https://doi.org/10.7705/biomedica.v36i2.2875 Cringoli, G., Rinaldi, L., Veneziano, V., Capelli, G., & Scala, A. (2004). The influence of flotation solution, sample dilution and the choice of McMaster slide area (volume) on the reliability of the McMaster technique in estimating the faecal egg counts of gastrointestinal strongyles and Dicrocoelium dendriticum in sheep. Veterinary Parasitology, 123(1–2), 121–131. https://doi.org/10.1016/j.vetpar.2004.05.021 Davis, C. N., Tyson, F., Cutress, D., Davies, E., Jones, D. L., Brophy, P. M., Prescott, A., Rose, M. T., Williams, M., Williams, H. W., & Jones, R. A. (2020). Rapid detection of Galba truncatula in water sources on pasture-land using loop-mediated isothermal amplification for control of trematode infections. Parasites & Vectors, 13(1), 496. https://doi.org/10.1186/s13071-020-04371-0 Davis, C. N., Winters, A., Milic, I., Devitt, A., Cookson, A., Brophy, P. M., & Morphew, R. M. (2020). Evidence of sequestration of triclabendazole and associated metabolites by extracellular vesicles of Fasciola hepatica. Scientific Reports, 10(1). https://doi.org/10.1038/s41598-020-69970-4 De Waal, T. (2021). Diseases of Dairy Animals: Parasites, Internal: Liver Flukes. Encyclopedia of Dairy Sciences: Third edition. 1 (451–458). https://doi.org/10.1016/b978-0-08-100596-5.00741-1 Delgado CE., Botero LM., Suarez, K. (2018). Infección por Fasciola hepática en equinos alrededor del mundo, revisión sistemática. Revista Sinergia. 3, 85–98. Domínguez, M. F., González-Miguel, J., Carmona, C., Dalton, J. P., Cwiklinski, K., Tort, J., Siles-Lucas, M. (2018). Low allelic diversity in vaccine candidates genes from different locations sustain hope for Fasciola hepatica immunization. Veterinary Parasitology, 258, 46–52. https://doi.org/10.1016/j.vetpar.2018.06.011 Donoso, S., Gadicke, P., Landaeta, C. (2016). Review zoonosis transmitted by food can affect its epidemiology, as a result of climate change and processes of globalization. Anim. Sci., Ex Agro-Ciencia, 32(2). Dutra, F., Navarro, M., Romero, A., Briano, C., Pereira, M., & Uzal, F. A. (2022). Spatial and seasonal analysis and geovisualization of Fasciola hepatica–free bovine bacillary hemoglobinuria outbreaks in eastern Uruguay, 1999–2019. Preventive Veterinary Medicine, 199, 105553. https://doi.org/10.1016/j.prevetmed.2021.105553 Elshraway, N. T., Mahmoud, W. G. (2017). Prevalence of fascioliasis (liver flukes) infection in cattle and buffaloes slaughtered at the municipal abattoir of El-Kharga, Egypt. Veterinary World, 10(8), 914–917. https://doi.org/10.14202/vetworld.2017.914-917 Evack, J. G., Schmidt, R. S., Boltryk, S. D., Voss, T. S., Batil, A. A., Ngandolo, B. N., Greter, H., Utzinger, J., Zinsstag, J., & Balmer, O. (2020). Molecular Confirmation of a Fasciola gigantica × Fasciola hepatica Hybrid in a Chadian Bovine. The Journal of Parasitology, 106(2), 316–322. https://doi.org/10.1645/19-66 Ezequiel, J., Ronquillo, J., Rodríguez, J., Robles, J., Castañeda, E. (2018). Situation of ovine and caprine fasciolasis with productive impact in San José Chiapa, Puebla. Fairweather, I., Brennan, G. P., Hanna, R. E. B., Robinson, M. W., & Skuce, P. J. (2020). Drug resistance in liver flukes. In International Journal for Parasitology: Drugs and Drug Resistance. 12 (39–59). https://doi.org/10.1016/j.ijpddr.2019.11.003 Flores, B., Pinedo, R., Suárez, F., Angelats, R., & Chávez, A. (2014). Comunidades rurales de Jauja, Perú prevalency of fascioliasis in llamas and alpacas in two rural communities of Jauja, Peru. In Rev Inv Vet Perú. 25(2). Forbes, A. (2017). Liver fluke infections in cattle and sheep. Livestock, 22(5), 250–256. https://doi.org/10.12968/live.2017.22.5.250 Gandhi, P., Schmitt, E. K., Chen, C. W., Samantray, S., Venishetty, V. K., & Hughes, D. (2019). Triclabendazole in the treatment of human fascioliasis: A review. Transactions of the Royal Society of Tropical Medicine and Hygiene, 113(12), 797–804. https://doi.org/10.1093/trstmh/trz093 Gandhi, P., Schmitt, E. K., Chen, C.-W., Samantray, S., Venishetty, V. K., & Hughes, D. (2019b). Triclabendazole in the treatment of human fascioliasis: a review. Transactions of The Royal Society of Tropical Medicine and Hygiene, 113(12), 797–804. https://doi.org/10.1093/trstmh/trz093 García, C., Eduardo, M., Judith, S., Medellín, P., Andrade, R. (2009). Ciencia y Agricultura. 7(2), 71–79. http://www.redalyc.org/articulo.oa?id=560058654008 George, S. D., George, A. J., Rolfe, P. F., & Emery, D. L. (2019). Comparative assessment of faecal diagnostics for detection and predictive modelling of endemic Fasciola hepatica infection in sheep and cattle on Australian farms. Veterinary Parasitology. 276. https://doi.org/10.1016/j.vpoa.2018.100001 González-Miguel, J., Becerro-Recio, D., & Siles-Lucas, M. (2021). Insights into Fasciola hepatica Juveniles: Crossing the Fasciolosis Rubicon. In Trends in Parasitology (Vol. 37, Issue 1, pp. 35–47). Elsevier Ltd. https://doi.org/10.1016/j.pt.2020.09.007 Hanna, R. E. B., McMahon, C., Ellison, S., Edgar, H. W., Kajugu, P. E., Gordon, A., Irwin, D., Barley, J. P., Malone, F. E., Brennan, G. P., & Fairweather, I. (2015). Fasciola hepatica: A comparative survey of adult fluke resistance to triclabendazole, nitroxynil and closantel on selected upland and lowland sheep farms in Northern Ireland using faecal egg counting, coproantigen ELISA testing and fluke histology. Veterinary Parasitology, 207(1–2), 34–43. https://doi.org/10.1016/j.vetpar.2014.11.016 Haridwal, S., Malatji, M. P., Mukaratirwa, S. (2021). Morphological and molecular characterization of Fasciola hepatica and Fasciola gigantica phenotypes from co-endemic localities in Mpumalanga and KwaZulu-Natal provinces of South Africa. Food and Waterborne Parasitology, 22. https://doi.org/10.1016/j.fawpar.2021.e00114 Hasan, M. M., Roy, B. C., Biswas, H., Rahman, M., Anisuzzaman, A., Alam, M. Z., & Talukder, Md. H. (2022). Efficacy of flukicides on Fasciola gigantica , a food-borne zoonotic helminth affecting livestock in Bangladesh. Parasitology, 149(10), 1339–1348. https://doi.org/10.1017/S0031182022000580 Hoang Quang, V., Levecke, B., do Trung, D., Devleesschauwer, B., Lam, B. V. T., Polman, K., Callens, S., Dorny, P., & Dermauw, V. (2022). Fasciola spp. in Southeast Asia: a systematic review and meta-analysis protocol. Systematic Reviews, 11(1), 138. https://doi.org/10.1186/s13643-022-02013-3 Howell, A., Baylis, M., Smith, R., Pinchbeck, G., Williams, D. (2015). Epidemiology and impact of Fasciola hepatica exposure in high-yielding dairy herds. Preventive Veterinary Medicine, 121(1–2), 41–48. https://doi.org/10.1016/j.prevetmed.2015.05.013 Isah, U. M. (2019). Studies on the prevalence of fascioliasis among ruminant animals in northern Bauchi state, north-eastern Nigeria. Parasite Epidemiology and Control, 5. https://doi.org/10.1016/j.parepi.2019.e00090 Iyiola, O. A., Shaibu, R. D., Shittu, O., Alayande, M. O., Rabiu, M., Sulaiman, M. K., Obarombi, G. T. (2021). DNA barcode identification of a tropical liver fluke (Fasciola gigantica) in cattle from Ilorin, Northcentral Nigeria. Biologia, 76(12), 3685–3692. https://doi.org/10.1007/s11756-021-00852-4 Jaja, I. F., Mushonga, B., Green, E., & Muchenje, V. (2017). Seasonal prevalence, body condition score and risk factors of bovine fasciolosis in South Africa. Veterinary and Animal Science, 4, 1–7. https://doi.org/10.1016/j.vas.2017.06.001 Jara-Campos, C., Escalante-Añorga, H., Siancas-Ruíz, F., Casana-Mantilla, W., & Benites-Murrieta, A. (1995). Neotropical Helminthology 123 ÓrganooficialdelaAsociaciónPeruanadeHelmintologíaeInvertebradosAfines(APHIA) (Vol. 13, Issue 2). Jaramillo, D. (2017). Implementación de buenas prácticas ovinas en la Hacienda La Lyda, municipio de Holguín Valle. https://ciencia.lasalle.edu.co/zootecnia John, B. C., Davies, D. R., Williams, D. J. L., Hodgkinson, J. E. (2019). A review of our current understanding of parasite survival in silage and stored forages, with a focus on Fasciola hepatica metacercariae. In Grass and Forage Science (Vol. 74, Issue 2, pp. 211–217). Blackwell Publishing Ltd. https://doi.org/10.1111/gfs.12429 Julon, D., Puicón, V., Chávez, A., Bardales, W., Gonzales, J., Vásquez, H., Maicelo, J. (2020). Prevalence of Fasciola hepatica and gastrointestinal parasites in bovine of the Amazonas Region, Peru. Revista de Investigaciones Veterinarias Del Peru, 31(1). https://doi.org/10.15381/rivep.v31i1.17560 Kahl, A., Samson-Himmelstjerna, G. von, Krücken, J., Ganter, M. (2021). Chronic wasting due to liver and rumen flukes in sheep. In Animals. 11(2): 1–20. https://doi.org/10.3390/ani11020549 Kain, D., Mukkala, A. N., Boggild, A. K. (2018). Prolonged antibiotic use leading to Clostridium difficile colitis in an ill returned traveller with acute fascioliasis. Journal of Travel Medicine, 25(1). https://doi.org/10.1093/jtm/tay012 Kamaludeen, J., Graham-Brown, J., Stephens, N., Miller, J., Howell, A., Beesley, N. J., Hodgkinson, J., Learmount, J., Williams, D. (2019). Lack of efficacy of triclabendazole against Fasciola hepatica is present on sheep farms in three regions of England, and Wales. Veterinary Record, 184(16). https://doi.org/10.1136/vr.105209 Kelley, J. M., Elliott, T. P., Beddoe, T., Anderson, G., Skuce, P., & Spithill, T. W. (2016). Current Threat of Triclabendazole Resistance in Fasciola hepatica. In Trends in Parasitology (Vol. 32, Issue 6, pp. 458–469). https://doi.org/10.1016/j.pt.2016.03.002 Khanjari, A., Bahonar, A., Fallah, S., Bagheri, M., Alizadeh, A., Fallah, M., Khanjari, Z. (2014a). Prevalence of fasciolosis and dicrocoeliosis in slaughtered sheep and goats in Amol Abattoir, Mazandaran, northern Iran. Asian Pacific Journal of Tropical Disease, 4(2), 120–124. https://doi.org/10.1016/S2222-1808(14)60327-3 Knubben-Schweizer, G., Torgerson, P. R. (2015). Bovine fasciolosis: Control strategies based on the location of Galba truncatula habitats on farms. Veterinary Parasitology, 208(1–2), 77–83. https://doi.org/10.1016/j.vetpar.2014.12.019 Lalrinkima, H., Lalchhandama, C., Jacob, S. S., Raina, O. K., Lallianchhunga, M. C. (2021). Fasciolosis in India: An overview. In Experimental Parasitology. 222. https://doi.org/10.1016/j.exppara.2021.108066 Lamb, J., Doyle, E., Barwick, J., Chambers, M., Kahn, L. (2021). Prevalence and gross pathology of liver fluke in macropods cohabiting livestock farms in north eastern NSW, Australia, and diagnosis using cELISA. International Journal for Parasitology: Parasites and Wildlife, 16, 199–207. https://doi.org/10.1016/j.ijppaw.2021.10.006 Liba, J. W., Atsanda, N. N., & Francis, M. I. (2017). Economic loss from liver condemnation due to Fasciolosis in slaughtered ruminants in Maiduguri abattoir, Borno State, Nigeria. Journal of Advanced Veterinary and Animal Research, 4(1), 65–70. https://doi.org/10.5455/javar.2017.d192 López-Villacís, I. C., Artieda-Rojas, J. R., Mera-Andrade, R. I., Muñoz-Espinoza, M. S., Rivera-Guerra, V. E., Cuadrado-Guevara, A. C., Zurita-Vásquez, J. H., & Montero-Recalde, M. A. (2017). Fasciola hepática: aspectos relevantes en la salud animal. J Selva And Anim Sci, 4(2), 137–146. María Díaz-Anaya, A., Chavarro-Tulcán, G. I., Pulido-Medellín, O., García-Corredor, D., Vargas-Avella, J. C. (2017). Coproparasitological study in grazing sheep in Boyacá, Colombia. In Rev. Salud Anim. 39(1). Martínez-Moreno A, Jimenez-Luque, Moreno T, Redondo E, Martín de las Mulas J, Pérez J. (1999). Liver pathology and immune response in experimental Fasciola hepatica infections of goats. Veterinary Parasitology, 82, 19–33. Mas-Coma, S., Agramunt, V. H., Valero, M. A. (2013). Direct and indirect affection of the central nervous system by Fasciola infection. In Handbook of Clinical Neurology (Vol. 114, pp. 297–310). https://doi.org/10.1016/B978-0-444-53490-3.00024-8 Mas-Coma, S., Agramunt, V. H., Valero, M. A. (2014). Neurological and Ocular Fascioliasis in Humans. In Advances in Parasitology. 84: 27–149. Academic Press. https://doi.org/10.1016/B978-0-12-800099-1.00002-8 Mensur S, Ansuar I, Tesfaye A, Abdulkaf K, Ahmed Y. (2016). Small ruminant fasciolosis and its economic impact in an export abattoir of Ethiopia. Livestock Research for Rural Development, 28. Micic, D., Oto, A., Charlton, M. R., Benoit, J.-L., & Siegler, M. (2020). Hiding in the Water. New England Journal of Medicine, 382(19), 1844–1849. https://doi.org/10.1056/nejmcps1902741 Montero, A. B., Rodríguez, I. S., Veirano, G. S., Geldhof, P., Rendón, D. Z. (2020). Prevalencia y carga parasitaria mensual de nematodos gastrointestinales y Fasciola hepatica en bovinos lecheros de dos distritos del Valle del Mantaro, Junín, Perú. Revista de Investigaciones Veterinarias Del Peru, 31(2). https://doi.org/10.15381/rivep.v31i2.17819 Morphological and molecular study of Fasciola spp. in sheep in Alkut city. (2019). International Journal of Biosciences (IJB), 14(01), 121–130. https://doi.org/10.12692/ijb/14.1.121-130 Muhammad Inuwa Adamu, Abba Haruna Adamu, & Najibullah Bakari Ado. (2022). The Prevalence of Fasciola hepatica in Slaughtered Goats and Sheep (A Case Study of Potiskum Abattoir). Network for Research and Development in Africa, 12(5), 55–61. http://www.arcnjournals.org/images/NRDA-IJPASR-12-5-6.pdf Najjari, M., Karimazar, M. R., Rezaeian, S., Ebrahimipour, M., Faridi, A. (2020). Prevalence and economic impact of cystic echinococcosis and liver fluke infections in slaughtered sheep and goat in north-central Iran, 2008–2018. Journal of Parasitic Diseases, 44(1), 17–24. https://doi.org/10.1007/s12639-019-01156-w Navarro, M. A., Uzal, F. A. (2020). Pathobiology and diagnosis of clostridial hepatitis in animals. Journal of Veterinary Diagnostic Investigation, 32(2), 192–202. https://doi.org/10.1177/1040638719886567 Nyindo, M., Lukambagire, A. H. (2015). Fascioliasis: An Ongoing Zoonotic Trematode Infection. In BioMed Research International. https://doi.org/10.1155/2015/786195 Nyirenda, S. S., Sakala, M., Moonde, L., Kayesa, E., Fandamu, P., Banda, F., Sinkala, Y. (2019). Prevalence of bovine Fascioliasis and economic impact associated with liver condemnation in abattoirs in Mongu district of Zambia. BMC Veterinary Research, 15(1). https://doi.org/10.1186/s12917-019-1777-0 Odeniran, P. O., Omolabi, K. F., Ademola, I. O. (2021). Economic impact assessment of small ruminant Fasciolosis in Nigeria using pooled prevalence obtained from literature and field epidemiological data. Veterinary Parasitology: Regional Studies and Reports, 24. https://doi.org/10.1016/j.vprsr.2021.100548 Oljira, W., Mideksa, B., Mekonnen, G., Kebebew, G., Jorga, E. (2022). Fasciolosis in sheep and goats slaughtered at abattoirs in Central Ethiopia and associated financial losses. Food and Waterborne Parasitology, 28, e00173. https://doi.org/10.1016/j.fawpar.2022.e00173 OPS., OMS. (2017). Manual Veterinario de Toma y Envío de Muestras. http://www.agricultura.gov.br/ Ormea, V., Gotuzzo, E. (2018). The «one health» approach in Perú. Revista Peruana de Medicina Experimental y Salud Publica, 35(4), 663–666. https://doi.org/10.17843/rpmesp.2018.354.4089 Ortiz-Pineda, M. C., Archila-Barrera, O. A., Bulla-Castañeda, D. M., Díaz-Anaya, A. M., Forero, J. C. G., Garcia-Corredor, D. J., Pulido-Medellín, M. O. (2021). Post mortem diagnosis of Fasciola hepatica in cattle slaughtered at the Sogamoso, Boyacá processing plant (Boyacá, Colombia). Revista de Investigaciones Veterinarias Del Peru, 32(5). https://doi.org/10.15381/rivep.v32i5.21341 Owiny, M. O., Obonyo, M. O., Gatongi, P. M., Fèvre, E. M. (2019). Prevalence and spatial distribution of trematode cercariae in vector snails within different agro-ecological zones in Western Kenya, 2016. Pan African Medical Journal, 32. https://doi.org/10.11604/pamj.2019.32.142.14418 Palacio, S., Bertor, J., Beltrao, M., Vázquez, A., Ortiz, R., Varona, M. (2019). Economic losses induced by Fasciola hepatica in cattle slaughtered in Chacuba slaughterhouse, Camagüey, Cuba. Cuban Journal of Agricultural Science, 53(1), 35–39. Pedroso, R. C. da C., Cunha, S. N. da, Cunha-Neto, A. da. (2020). Helmintos de importância para saúde pública em alfaces no Brasil: uma revisão sistemática/ Helminths of public health importance in lettuce in Brazil: a systematic review. Brazilian Journal of Health Review, 3(6), 19200–19225. https://doi.org/10.34119/bjhrv3n6-304 Piedrafita, D., Spithill, T. W., Smith, R. E., Raadsma, H. W. (2010). Improving animal and human health through understanding liver fluke immunology. In Parasite Immunology. 32(8): 572–581. https://doi.org/10.1111/j.1365-3024.2010.01223.x Pinilla, J., Muñoz, A., Uribe, N. (2020). Prevalence and risk factors associated with liver fluke Fasciola hepatica in cattle and sheep in three municipalities in the Colombian Northeastern Mountains. Veterinary Parasitology: Regional Studies and Reports, 19. https://doi.org/10.1016/j.vprsr.2019.100364 Pinilla León, J. C., Delgado, N. U., Florez, A. A. (2019). Prevalence of gastrointestinal parasites in cattle and sheep in three municipalities in the Colombian Northeastern Mountain. Veterinary World, 12(1), 48–54. https://doi.org/10.14202/vetworld.2019.48-54 Pulido-Medellín, M. O., Chavarro-Tulcán, G. I., & Díaz-Anaya, A. M. (2020). Prevalence and risk factors of gastrointestinal parasites in sheep from Ubaté, Cundinamarca, Colombia. Revista Brasileira de Medicina Veterinaria, 42(1). https://doi.org/10.29374/2527-2179.BJVM098819 Qureshi, A. W., Zeb, A., Mansoor, A., Hayat, A., & Mas-Coma, S. (2019). Fasciola hepatica infection in children actively detected in a survey in rural areas of Mardan district, Khyber Pakhtunkhawa province, northern Pakistan. Parasitology International, 69, 39–46. https://doi.org/10.1016/j.parint.2018.11.003 Rashid, M., Rashid, M. I., Akbar, H., Ahmad, L., Hassan, M. A., Ashraf, K., Saeed, K., Gharbi, M. (2019). A systematic review on modelling approaches for economic losses studies caused by parasites and their associated diseases in cattle. In Parasitology. 146(2): 129–141). https://doi.org/10.1017/S0031182018001282 Rassol, A. M., Ahmed, A. M., Sobhy, H. M., Abdelgayed, S. S., Hekal, S. H. (2020). Effects of Fascioliasis on the Economic Losses of Beef Liver at Abu Simbel Abattoir, Aswan Governorate, Egypt. Advances in Animal and Veterinary Sciences, 8(11), 1175–1179. https://doi.org/10.17582/journal.aavs/2020/8.11.1175.1179 Recalde-Reyes, D. P., Padilla, L., Giraldo, M. I., Segovia, L. J., González, M. M., Osorio, J. C. (2014). Prevalence of Fasciola hepatica in humans and cattle in the department of Quindio-Colombia 2012-2013. Infectio, 18(4), 153–157. https://doi.org/10.1016/j.infect.2014.09.001 Robaina, E. R. C., Álvarez Escobar, C. M., Torres, A., Semper, A. I. (2020). Hepatic fasciolosis, a series of cases reported in Matanzas, Cuba. https://orcid.org/0000-0002-7932-9401 Ruhoollah, Khan, W., Al-Jabr, O. A., Khan, T., Khan, A., El-Ghareeb, W. R., Aguilar-Marcelino, L., Hussein, E. O. S., Alhimaidi, A. R., Swelum, A. A. (2023). Prevalence of gastrointestinal parasite in small ruminants of District Dir Upper Khyber Pakhtunkhwa Province of Pakistan. Brazilian Journal of Biology, 83. https://doi.org/10.1590/1519-6984.248978 Ruiz-Campillo, M. T., Molina-Hernandez, V., Escamilla, A., Stevenson, M., Perez, J., Martinez-Moreno, A., Donnelly, S., Dalton, J. P., Cwiklinski, K. (2017). Immune signatures of pathogenesis in the peritoneal compartment during early infection of sheep with Fasciola hepatica. Scientific Reports, 7(1). https://doi.org/10.1038/s41598-017-03094-0 Sarkari, B., & Khabisi, S. A. (2017). Immunodiagnosis of human Fascioliasis: An update of concepts and performances of the serological assays. In Journal of Clinical and Diagnostic Research. 11(6):05-10. https://doi.org/10.7860/JCDR/2017/26066.10086 Sharma, K. (2020). Gastrointestinal Helminthic Challenges in Sheep and Goats in Afro-Asian Region: A Review. Journal of Animal Research, 10(1). https://doi.org/10.30954/2277-940x.01.2020.1 Shrestha, S., Barratt, A., Fox, N. J., Vosough Ahmadi, B., Hutchings, M. R. (2020). Financial Impacts of Liver Fluke on Livestock Farms Under Climate Change–A Farm Level Assessment. Frontiers in Veterinary Science, 7. https://doi.org/10.3389/fvets.2020.564795 Siles-Lucas, M., Becerro-Recio, D., Serrat, J., González-Miguel, J. (2021). Fascioliasis and Fasciolopsiasis: Current knowledge and future trends. In Research in Veterinary Science. 134:27–35. https://doi.org/10.1016/j.rvsc.2020.10.011 Silva, A. E. P., Freitas, C. da C., Dutra, L. V., Molento, M. B. (2020). Correlation between climate data and land altitude for Fasciola hepatica infection in cattle in Santa Catarina, Brazil. Revista Brasileira de Parasitologia Veterinaria, 29(3), 1–7. https://doi.org/10.1590/s1984-29612020065 Singh, D. K., Singh, V. K., Singh, R. N., Kumar, P. (2021). Fasciolosis: Causes, Challenges and Controls. Springer Singapore. https://doi.org/10.1007/978-981-16-0259-7 Soosaraei, M., Fakhar, M., Teshnizi, S. H., Emameh, R. Z., Hezarjaribi, H. Z., Asfaram, S., Faridnia, R., Kalani, H. (2020). Status of Fasciolosis among domestic ruminants in Iran based on abattoir data: a systematic review and meta-analysis. Annals of Parasitology, 66(1). https://doi.org/10.17420/ap6601.240 Spithill, T. W., Piedrafitat, D., Smooker, P. M. (1997). Immunological Approaches for the Control of Fasciolosis. In Australian Society for Parasitology. 27:10. Squire, S. A., Yang, R., Robertson, I., Ayi, I., Squire, D. S., Ryan, U. (2018). Gastrointestinal helminths in farmers and their ruminant livestock from the Coastal Savannah zone of Ghana. Parasitology Research, 117(10), 3183–3194. https://doi.org/10.1007/s00436-018-6017-1 Sripa, B., Echaubard, P. (2017). Prospects and Challenges towards Sustainable Liver Fluke Control. In Trends in Parasitology. 33(10): 799–812. https://doi.org/10.1016/j.pt.2017.06.002 Sugiyama, T., Ichikawa-Seki, M., Sato, H., Kounosu, A., Tanaka, M., Maruyama, H. (2021). Enzyme-linked immunosorbent assay (ELISA) using recombinant Fasciola cathepsin L1 for the diagnosis of human fasciolosis caused by Fasciola hepatica/gigantica hybrid type. Parasitology International, 82. https://doi.org/10.1016/j.parint.2021.102311 Tadesse, A., Usman, J. (2022). Status of small ruminant Fasciolosis and diagnostic test evaluation at Haramaya town municipal abattoir, East Harrarghe Zone, Ethiopia. Ethiopian Veterinary Journal, 26(1), 82–104. https://doi.org/10.4314/evj.v26i1.6 Taghipour, A., Zaki, L., Rostami, A., Foroutan, M., Ghaffarifar, F., Fathi, A., Abdoli, A. (2019). Highlights of human ectopic fascioliasis: a systematic review. In Infectious Diseases. 51(11–12):785–792. https://doi.org/10.1080/23744235.2019.1663362 Tidman, R., Abela-Ridder, B., De Castañeda, R. R. (2021). The impact of climate change on neglected tropical diseases: A systematic review. In Transactions of the Royal Society of Tropical Medicine and Hygiene. 115(2):147–168. https://doi.org/10.1093/trstmh/traa192 Torrel, S., Vásquez, D., Moncada, R., Coronado, F., Aguilar, N., García, T., Castro, D. (2020). Ectopic Fasciola hepatica in lung of slaughtered cattle in the municipal abattoir of Cajamarca, Peru. Revista de Investigaciones Veterinarias Del Peru, 31(3). https://doi.org/10.15381/RIVEP.V31I3.18721 Tran, D. H., Hung, H. T. T. (2020). Detecting Fasciola hepatica and Fasciola gigantica microRNAs with loop-mediated isothermal amplification (LAMP). Journal of Parasitic Diseases, 44(2), 364–373. https://doi.org/10.1007/s12639-019-01164-w Tsega, M., Dereso, S., Getu, A. (2015). A Review on Ruminant Fasciolosis. OALib, 02(08), 1–8. https://doi.org/10.4236/oalib.1101655 Tsegaye, G., & Abebe, K. (2021). A Review on Bovine Fasciolosis. Global Veterinaria, 23(3), 134–141. https://doi.org/10.5829/idosi.gv.2021.134.141 Uribe, N., Becerra, W. M., & Velásquez, L. E. (2014). Lymnaea cousini, huésped de Fasciola hepatica en el trópico alto andino de Colombia, y sus nuevos haplotipos, confirmados con el marcador mitocondrial del gen del citocromo oxidasa I. Biomedica, 34(4), 598–604. https://doi.org/10.7705/biomedica.v34i4.2312 Uruburu, M., Bedoya, J., Velásquez, L. (2013). ELISA indirecta para el diagnóstico de Fasciolosis bovina en leche. Rev CES Med Vet Zoot, 8(2), 93–100. https://doi.org/10.21615/2850 Valderrama, A. (2016). Prevalencia de Fascioliasis en animales poligástricos de Perú, 1985-2015. Revista de Medicina Veterinaria, 32, 121. https://doi.org/10.19052/mv.3861 Valero, M. A., Pérez-Crespo, I., Khoubbane, M., Artigas, P., Panova, M., Ortiz, P., Maco, V., Espinoza, J. R., & Mas-Coma, S. (2012). Fasciola hepatica phenotypic characterization in Andean human endemic areas: Valley versus altiplanic patterns analysed in liver flukes from sheep from Cajamarca and Mantaro, Peru. Infection, Genetics and Evolution, 12(2), 403–410. https://doi.org/10.1016/j.meegid.2012.01.009 Vázquez, A. A., Alba, A., Alda, P., Vittecoq, M., & Hurtrez-Boussès, S. (2022). On the arrival of fasciolosis in the Americas. In Trends in Parasitology. 38(3):195–204. https://doi.org/10.1016/j.pt.2021.12.001 Vineer, H., Morgan, E. R., Hertzberg, H., Bartley, D. J., Bosco, A., Charlier, J., Chartier, C., Claerebout, E., de Waal, T., Hendrickx, G., Hinney, B., Höglund, J., Jez Ek, J. I., Kašný, M., Keane, O. M., Martínez-Valladares, M., Mateus, T. L., McIntyre, J., Mickiewicz, M., … Rinaldi, L. (2020). Increasing importance of anthelmintic resistance in European livestock: Creation and meta-analysis of an open database. Parasite, 27. https://doi.org/10.1051/parasite/2020062 VSierra, R., Martínez, R. A., Gutiérrez, R., Dolores, C., Uribe, N. (2017a). Estandarización de ELISA para el diagnóstico de Fasciolosis bovina, ovina y humana. Revista de La Universidad Industrial de Santander. Salud, 49(4), 549–556. https://doi.org/10.18273/revsal.v49n4-2017004 Wu, Z., Wang, J., Meng, Z., Jin, W., He, K., Zhang, W., Di, W. (2021). Identification of Fasciola spp. based on ITS-2 reveals the Fasciola gigantica infection in buffaloes in Nanning city, South China. Veterinary Parasitology, 300, 109585. https://doi.org/10.1016/j.vetpar.2021.109585 Zafar, A., Khan, M. K., Ud Din Sindhu, Z., Abbas, R. Z., Masood, S., Abbas, Z., Mahmood, M. S., Saleemi, M. K., Khan, J. A., Hussain, R., Naseer, M. U., Iqbal, Z., Javed, H. (2019). Seroprevalence of Fasciola hepatica in small ruminants of District Chakwal, Punjab, Pakistan. Pakistan Veterinary Journal, 39(1), 96–100. https://doi.org/10.29261/pakvetj/2018.024 Zeng, M., Wang, X., Lan, Z., Guo, X., Jiang, Y., Wu, T., Chang, Q., Wang, C. (2022). Identification of new polymorphic positions in rDNA sequences of the “intermediate” Fasciola forms. Parasitology International. 88, 102555. https://doi.org/10.1016/j.parint.2022.102555 Zerna, G., Spithill, T. W., & Beddoe, T. (2021). Current status for controlling the overlooked caprine fasciolosis. Animals. 11(6). https://doi.org/10.3390/ani11061819 Zewde, A., Bayu, Y., Wondimu, A. (2019). Prevalence of Bovine Fasciolosis and Its Economic Loss due to Liver Condemnation at Wolaita Sodo Municipal Abattair, Ethiopia. Veterinary Medicine International, 2019. https://doi.org/10.1155/2019/9572373 |
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García Corredor, Diego JoséOrtiz Pineda, Melissa Camila2024-03-09T22:54:48Z2024-03-09T22:54:48Z2022Ortiz Pineda, M. C. (2022). Seroprevalencia de fasciola hepatica en pequeños rumiantes de Boavita, Boyacá. (Trabajo de pregrao). Universidad Pedagógica y Tecnológica de Colombia. Facultad de Ciencias Agropecuarias, Tunja. https://repositorio.uptc.edu.co//handle/001/9611https://repositorio.uptc.edu.co//handle/001/9611Spa: La Fascioliasis, causada por Fasciola hepatica, afecta globalmente al ganado. Técnicas de diagnóstico tradicionales tienen limitaciones, retrasando la detección. Enfoques inmunológicos como ELISA mejoran la sensibilidad. Una investigación en Boavita, Boyacá, encontró una seroprevalencia del 72.96%, mayor en ovinos (84.62%) que en caprinos (70.40%). Razas como Alpina y Nubiana en caprinos, y Camura en ovinos, mostraron asociación estadística con la seropositividad. La presencia de caracoles está vinculada a la enfermedad. Este conocimiento epidemiológico informa sobre la dinámica de transmisión y guía estrategias de manejo y control.Bibliografía y webgrafía: páginas 45-55.PregradoMédico Veterinario y Zootecnista1 recurso en línea (55 páginas) : ilustracionesapplication/pdfUniversidad Pedagógica y Tecnológica de ColombiaFacultad de Ciencias AgropecuariasTunjaMedicina Veterinaria y ZootecniaCopyright (c) 2022 Universidad Pedagógica y Tecnológica de Colombiahttps://creativecommons.org/licenses/by/4.0/info:eu-repo/semantics/openAccessLicencia Creative Commons Atribución-NoComercial-SinDerivadas 4.0 Internacional (CC BY-NC-ND 4.0)http://purl.org/coar/access_right/c_abf2Seroprevalencia de Fasciola hepatica en pequeños rumiantes de Boavita, BoyacáTrabajo de grado pregradoshttp://purl.org/coar/resource_type/c_7a1finfo:eu-repo/semantics/bachelorThesisinfo:eu-repo/semantics/publishedVersionTexthttps://purl.org/redcol/resource_type/TPhttp://purl.org/coar/version/c_970fb48d4fbd8a85Abunna, F., Asfaw, L., Megersa, B., & Regassa, A. (2010). Bovine fasciolosis: Coprological, abattoir survey and its economic impact due to liver condemnation at Soddo municipal abattoir, Southern Ethiopia. Tropical Animal Health and Production, 42(2), 289–292. https://doi.org/10.1007/s11250-009-9419-3Acevedo-Charry, O., Murillo-Bedoya, D., Buitrago-Cardona, A., Ospina-L, A. M., Medina-Uribe, C. A., Colón-Piñeiro, Z., Gómez-Valencia, B., Herrera-Varón, Y., & Ochoa-Quintero, J. M. (2021). Passive acoustic sampling data of the Colección de Sonidos Ambientales Mauricio Álvarez-Rebolledo - Instituto Humboldt (IAvH-CSA) during 2018 and 2019 in Colombia. Data in Brief, 34. https://doi.org/10.1016/j.dib.2020.106648Addy, F., Gyan, K., Arhin, E., & Wassermann, M. (2020). Prevalence of bovine fasciolosis from the Bolgatanga abattoir, Ghana. Scientific African, 8. https://doi.org/10.1016/j.sciaf.2020.e00469Ahmad, T., Imran, M., Ahmad, K., Khan, M., Baig, M., Al-Rifai, R. H., & Al-Omari, B. (2021). A Bibliometric Analysis and Global Trends in Fascioliasis Research: A Neglected Tropical Disease. Animals, 11(12), 3385. https://doi.org/10.3390/ani11123385Alcaldía de Boavita. (7 de septiembre del 2022). Municipio de Boavita.http://www.boavita-boyaca.gov.co/Alemneh, T. (2019). An Introductory to Fasciolosis. Concepts of Dairy & Veterinary Sciences, 2(3). https://doi.org/10.32474/cdvs.2019.02.000139Alstedt, U., Voigt, K., Jäger, M. C., Knubben-Schweizer, G., Zablotski, Y., Strube, C., & Wenzel, C. (2022). Rumen and Liver Fluke Infections in Sheep and Goats in Northern and Southern Germany. Animals, 12(7). https://doi.org/10.3390/ani12070876Alvarez, C. A., Jex, A. R., Gasser, R. B., & Scheerlinck, J. P. Y. (2014). Techniques for the Diagnosis of Fasciola Infections in Animals. Room for Improvement. In Advances in Parasitology (Vol. 85, pp. 65–107). Academic Press. https://doi.org/10.1016/B978-0-12-800182-0.00002-7Amina K, N., Ouchene, N., & Dahmani, A. (2018). Fasciolosis due to Fasciola hepatica in ruminants in abattoirs and its economic impact in two regions in Algeria. https://www.researchgate.net/publication/324769609Anjum, R., Khan, M. N., Sajid, M. S., & Javed, M. T. (2014). Frequency distribution of fasciolosis in small ruminants population at district Sargodha. Global Veterinaria, 12(1), 26–32. https://doi.org/10.5829/idosi.gv.2014.12.01.81152Arenal, A., García, Y., Quesada, L., Velázquez, D., Sánchez, D., Peña, M., Suárez, A., Díaz, A., Sánchez, Y., Casaert, S., van Dijk, J., Vercruysse, J., & Charlier, J. (2018). Risk factors for the presence of Fasciola hepatica antibodies in bulk-milk samples and their association with milk production decreases, in Cuban dairy cattle. BMC Veterinary Research, 14(1). https://doi.org/10.1186/s12917-018-1654-2Arias-Pacheco, C., Lucas, J. R., Rodríguez, A., Córdoba, D., & Lux-Hoppe, E. G. (2020). Economic impact of the liver condemnation of cattle infected with Fasciola hepatica in the Peruvian Andes. Tropical Animal Health and Production, 52(4), 1927–1932. https://doi.org/10.1007/s11250-020-02211-yBadirzadeh, A., & Sabzevari, S. (2017). Hepatic fascioliasis in Mashhad, Northeast Iran: First report. Revista Da Sociedade Brasileira de Medicina Tropical, 50(4), 571–574. https://doi.org/10.1590/0037-8682-0526-2016Barreto, T., Alfonso, Y., Lafaye, P., García Lázaro, M. del P., Pérez, L. A., Herrera-Velit, P., & Espinoza, J. R. (2018). Single-chain antibodies from alpaca for the detection of Fasciola hepatica antigens. Revista Peruana de Medicina Experimental y Salud Publica, 35(4), 573–580. https://doi.org/10.17843/rpmesp.2018.354.3101Becerra Rozo, W. (2001). Consideraciones sobre estrategias sostenibles para el control de Fasciola hepática en Latinoamérica. In Rev Col Cienc Pec. 14(1).Biruk Alemu Basore. (2019). Bovine Fasciolosis in Ethiopia-A review Journal of Veterinary and Animal Research Bovine Fasciolosis in Ethiopia-A review. Journal of Veterinary and Animal Research, 2(2), 1–12. www.scholarena.comBolaños, R. (2021). Trematodes: una revisión a la importancia de Fasciola hepatica. In Revista Veterinaria ISSN. 32(2). www.vet.unne.edu.arBozorgomid, A., Rouhani, S., Harandi, M. F., Ichikawa-Seki, M., & Raeghi, S. (2020). Genetic diversity and distribution of Fasciola hepatica haplotypes in Iran: Molecular and phylogenetic studies. Veterinary Parasitology: Regional Studies and Reports, 19. https://doi.org/10.1016/j.vprsr.2019.100359Calvani, N. E. D., George, S. D., Windsor, P. A., Bush, R. D., & Šlapeta, J. (2018). Comparison of early detection of Fasciola hepatica in experimentally infected Merino sheep by real-time PCR, coproantigen ELISA and sedimentation. Veterinary Parasitology, 251, 85–89. https://doi.org/10.1016/j.vetpar.2018.01.004Calvani, N. E. D., & Šlapeta, J. (2021). Fasciola Species Introgression: Just a Fluke or Something More? In Trends in Parasitology. 7(1): 25–34. https://doi.org/10.1016/j.pt.2020.09.008Caravedo, M. A., & Cabada, M. (2020). Human Fascioliasis: Current Epidemiological Status and Strategies for Diagnosis, Treatment, and Control. Research and Reports in Tropical Medicine, Volume 11, 149–158. https://doi.org/10.2147/rrtm.s237461Carmona, C., & Tort, J. F. (2017). Fasciolosis in South America: epidemiology and control challenges. Journal of Helminthology, 91(2), 99–109. https://doi.org/10.1017/S0022149X16000560elik, ., Aslan el k, B. (n.d.). Investigation of the Prevalence of Fasciola hepatica in Small Ruminants in the Siirt Region, Turkey (Vol. 13, Issue 4). http://ijpa.tums.ac.irCeli-Erazo, M., Alda, P., Montenegro-Franco, M., Pavon, D., Minda-Aluisa, E., Calvopiña, M., Pointier, J. P., Hurtrez-Boussès, S., Cevallos, W., Benítez-Ortíz, W., & Rodríguez-Hidalgo, R. (2020). Prevalence of Fasciola hepatica infection in Galba cousini and Galba schirazensis from an Andean region of Ecuador. Veterinary Parasitology: Regional Studies and Reports, 20. https://doi.org/10.1016/j.vprsr.2020.100390Charlier, J., Rinaldi, L., Musella, V., Ploeger, H. W., Chartier, C., Vineer, H. R., Hinney, B., von Samson-Himmelstjerna, G., Băcescu, B., Mickiewicz, M., Mateus, T. L., Martinez-Valladares, M., Quealy, S., Azaizeh, H., Sekovska, B., Akkari, H., Petkevicius, S., Hektoen, L., Höglund, J., … Claerebout, E. (2020). Initial assessment of the economic burden of major parasitic helminth infections to the ruminant livestock industry in Europe. Preventive Veterinary Medicine, 182. https://doi.org/10.1016/j.prevetmed.2020.105103Científico, A., Pinzón, G., Pérez, E., Pinzón, E. G., Cárdenas, J. P., Marín, S. A., & Linares Villalba, S. (2016). Prevalence of bovine Fasciolosis in a zone of caldas Colombia with evidences of the disease. www.ucaldas.edu.coClavijo, T. N. A. (2016). Caracterización de la agrocadena ovino-caprina en el municipio de Suesca vereda Tausaquira (Cundinamarca). https://ciencia.lasalle.edu.co/administracion_agronegocios.Colmenares, C., Méndez, L., Díaz-Bello, Z., Alarcón de Noya, B. (2007). Antígeno excreción-secreción de Fasciola hepatica: ultrafiltración y aplicación en inmunodiagnóstico. Acta Bioquímica Clínica Latinoamericana, 41 (2),259-266.Como, Zambrano, M. M., Medina, P. M., Pozo Muñoz, D. J., Andrade, S. C., Franco Diagnóstico, H. A., Elena Muñoz Zambrano, M., Placencia Medina, M., Andree Del Pozo Muñoz, J., Sevilla Andrade, C., & Huiza Franco, A. (2020). Serological diagnosis of Fasciola hepatica infection: a systematic review. In Rev Gastroenterol Peru (Vol. 40, Issue 2).Cornejo, H., Oblitas, fátima, & Cruzado, S. (2010). Evaluación de una prueba de Elisa con antígeno metabólico de Fasciola hepatica para el diagnóstico de Fasciolosis humana en cajamarca, perú. In Rev Peru Med Exp Salud Publica. 27(4).Corrales, Y., Ferrer, E., Fernández, J., Gauta, J., García, M., Aguirre, A., & Pérez, A. (2021). Diagnosis and Risk Factors of Bovine and Human Fascioliasis in Cattle Farms from a Venezuelan Andean Rural Area. Acta Parasitologica, 66(3), 1048–1054. https://doi.org/10.1007/s11686-021-00341-3Corral-Ruiz, G. M., & Sánchez-Torres, L. E. (2020). Fasciola hepatica-derived molecules as potential immunomodulators. Acta Tropica. 210. https://doi.org/10.1016/j.actatropica.2020.105548Correa, S., Martínez, Y. L., López, J. L., & Velásquez, L. E. (2016). Evaluación de la técnica modificada de Dennis para el diagnóstico de fasciolosis bovina. Biomedica, 36, 64–68. https://doi.org/10.7705/biomedica.v36i2.2875Cringoli, G., Rinaldi, L., Veneziano, V., Capelli, G., & Scala, A. (2004). The influence of flotation solution, sample dilution and the choice of McMaster slide area (volume) on the reliability of the McMaster technique in estimating the faecal egg counts of gastrointestinal strongyles and Dicrocoelium dendriticum in sheep. Veterinary Parasitology, 123(1–2), 121–131. https://doi.org/10.1016/j.vetpar.2004.05.021Davis, C. N., Tyson, F., Cutress, D., Davies, E., Jones, D. L., Brophy, P. M., Prescott, A., Rose, M. T., Williams, M., Williams, H. W., & Jones, R. A. (2020). Rapid detection of Galba truncatula in water sources on pasture-land using loop-mediated isothermal amplification for control of trematode infections. Parasites & Vectors, 13(1), 496. https://doi.org/10.1186/s13071-020-04371-0Davis, C. N., Winters, A., Milic, I., Devitt, A., Cookson, A., Brophy, P. M., & Morphew, R. M. (2020). Evidence of sequestration of triclabendazole and associated metabolites by extracellular vesicles of Fasciola hepatica. Scientific Reports, 10(1). https://doi.org/10.1038/s41598-020-69970-4De Waal, T. (2021). Diseases of Dairy Animals: Parasites, Internal: Liver Flukes. Encyclopedia of Dairy Sciences: Third edition. 1 (451–458). https://doi.org/10.1016/b978-0-08-100596-5.00741-1Delgado CE., Botero LM., Suarez, K. (2018). Infección por Fasciola hepática en equinos alrededor del mundo, revisión sistemática. Revista Sinergia. 3, 85–98.Domínguez, M. F., González-Miguel, J., Carmona, C., Dalton, J. P., Cwiklinski, K., Tort, J., Siles-Lucas, M. (2018). Low allelic diversity in vaccine candidates genes from different locations sustain hope for Fasciola hepatica immunization. Veterinary Parasitology, 258, 46–52. https://doi.org/10.1016/j.vetpar.2018.06.011Donoso, S., Gadicke, P., Landaeta, C. (2016). Review zoonosis transmitted by food can affect its epidemiology, as a result of climate change and processes of globalization. Anim. Sci., Ex Agro-Ciencia, 32(2).Dutra, F., Navarro, M., Romero, A., Briano, C., Pereira, M., & Uzal, F. A. (2022). Spatial and seasonal analysis and geovisualization of Fasciola hepatica–free bovine bacillary hemoglobinuria outbreaks in eastern Uruguay, 1999–2019. Preventive Veterinary Medicine, 199, 105553. https://doi.org/10.1016/j.prevetmed.2021.105553Elshraway, N. T., Mahmoud, W. G. (2017). Prevalence of fascioliasis (liver flukes) infection in cattle and buffaloes slaughtered at the municipal abattoir of El-Kharga, Egypt. Veterinary World, 10(8), 914–917. https://doi.org/10.14202/vetworld.2017.914-917Evack, J. G., Schmidt, R. S., Boltryk, S. D., Voss, T. S., Batil, A. A., Ngandolo, B. N., Greter, H., Utzinger, J., Zinsstag, J., & Balmer, O. (2020). Molecular Confirmation of a Fasciola gigantica × Fasciola hepatica Hybrid in a Chadian Bovine. The Journal of Parasitology, 106(2), 316–322. https://doi.org/10.1645/19-66Ezequiel, J., Ronquillo, J., Rodríguez, J., Robles, J., Castañeda, E. (2018). Situation of ovine and caprine fasciolasis with productive impact in San José Chiapa, Puebla.Fairweather, I., Brennan, G. P., Hanna, R. E. B., Robinson, M. W., & Skuce, P. J. (2020). Drug resistance in liver flukes. In International Journal for Parasitology: Drugs and Drug Resistance. 12 (39–59). https://doi.org/10.1016/j.ijpddr.2019.11.003Flores, B., Pinedo, R., Suárez, F., Angelats, R., & Chávez, A. (2014). Comunidades rurales de Jauja, Perú prevalency of fascioliasis in llamas and alpacas in two rural communities of Jauja, Peru. In Rev Inv Vet Perú. 25(2).Forbes, A. (2017). Liver fluke infections in cattle and sheep. Livestock, 22(5), 250–256. https://doi.org/10.12968/live.2017.22.5.250Gandhi, P., Schmitt, E. K., Chen, C. W., Samantray, S., Venishetty, V. K., & Hughes, D. (2019). Triclabendazole in the treatment of human fascioliasis: A review. Transactions of the Royal Society of Tropical Medicine and Hygiene, 113(12), 797–804. https://doi.org/10.1093/trstmh/trz093Gandhi, P., Schmitt, E. K., Chen, C.-W., Samantray, S., Venishetty, V. K., & Hughes, D. (2019b). Triclabendazole in the treatment of human fascioliasis: a review. Transactions of The Royal Society of Tropical Medicine and Hygiene, 113(12), 797–804. https://doi.org/10.1093/trstmh/trz093García, C., Eduardo, M., Judith, S., Medellín, P., Andrade, R. (2009). Ciencia y Agricultura. 7(2), 71–79. http://www.redalyc.org/articulo.oa?id=560058654008George, S. D., George, A. J., Rolfe, P. F., & Emery, D. L. (2019). Comparative assessment of faecal diagnostics for detection and predictive modelling of endemic Fasciola hepatica infection in sheep and cattle on Australian farms. Veterinary Parasitology. 276. https://doi.org/10.1016/j.vpoa.2018.100001González-Miguel, J., Becerro-Recio, D., & Siles-Lucas, M. (2021). Insights into Fasciola hepatica Juveniles: Crossing the Fasciolosis Rubicon. In Trends in Parasitology (Vol. 37, Issue 1, pp. 35–47). Elsevier Ltd. https://doi.org/10.1016/j.pt.2020.09.007Hanna, R. E. B., McMahon, C., Ellison, S., Edgar, H. W., Kajugu, P. E., Gordon, A., Irwin, D., Barley, J. P., Malone, F. E., Brennan, G. P., & Fairweather, I. (2015). Fasciola hepatica: A comparative survey of adult fluke resistance to triclabendazole, nitroxynil and closantel on selected upland and lowland sheep farms in Northern Ireland using faecal egg counting, coproantigen ELISA testing and fluke histology. Veterinary Parasitology, 207(1–2), 34–43. https://doi.org/10.1016/j.vetpar.2014.11.016Haridwal, S., Malatji, M. P., Mukaratirwa, S. (2021). Morphological and molecular characterization of Fasciola hepatica and Fasciola gigantica phenotypes from co-endemic localities in Mpumalanga and KwaZulu-Natal provinces of South Africa. Food and Waterborne Parasitology, 22. https://doi.org/10.1016/j.fawpar.2021.e00114Hasan, M. M., Roy, B. C., Biswas, H., Rahman, M., Anisuzzaman, A., Alam, M. Z., & Talukder, Md. H. (2022). Efficacy of flukicides on Fasciola gigantica , a food-borne zoonotic helminth affecting livestock in Bangladesh. Parasitology, 149(10), 1339–1348. https://doi.org/10.1017/S0031182022000580Hoang Quang, V., Levecke, B., do Trung, D., Devleesschauwer, B., Lam, B. V. T., Polman, K., Callens, S., Dorny, P., & Dermauw, V. (2022). Fasciola spp. in Southeast Asia: a systematic review and meta-analysis protocol. Systematic Reviews, 11(1), 138. https://doi.org/10.1186/s13643-022-02013-3Howell, A., Baylis, M., Smith, R., Pinchbeck, G., Williams, D. (2015). Epidemiology and impact of Fasciola hepatica exposure in high-yielding dairy herds. Preventive Veterinary Medicine, 121(1–2), 41–48. https://doi.org/10.1016/j.prevetmed.2015.05.013Isah, U. M. (2019). Studies on the prevalence of fascioliasis among ruminant animals in northern Bauchi state, north-eastern Nigeria. Parasite Epidemiology and Control, 5. https://doi.org/10.1016/j.parepi.2019.e00090Iyiola, O. A., Shaibu, R. D., Shittu, O., Alayande, M. O., Rabiu, M., Sulaiman, M. K., Obarombi, G. T. (2021). DNA barcode identification of a tropical liver fluke (Fasciola gigantica) in cattle from Ilorin, Northcentral Nigeria. Biologia, 76(12), 3685–3692. https://doi.org/10.1007/s11756-021-00852-4Jaja, I. F., Mushonga, B., Green, E., & Muchenje, V. (2017). Seasonal prevalence, body condition score and risk factors of bovine fasciolosis in South Africa. Veterinary and Animal Science, 4, 1–7. https://doi.org/10.1016/j.vas.2017.06.001Jara-Campos, C., Escalante-Añorga, H., Siancas-Ruíz, F., Casana-Mantilla, W., & Benites-Murrieta, A. (1995). Neotropical Helminthology 123 ÓrganooficialdelaAsociaciónPeruanadeHelmintologíaeInvertebradosAfines(APHIA) (Vol. 13, Issue 2).Jaramillo, D. (2017). Implementación de buenas prácticas ovinas en la Hacienda La Lyda, municipio de Holguín Valle. https://ciencia.lasalle.edu.co/zootecniaJohn, B. C., Davies, D. R., Williams, D. J. L., Hodgkinson, J. E. (2019). A review of our current understanding of parasite survival in silage and stored forages, with a focus on Fasciola hepatica metacercariae. In Grass and Forage Science (Vol. 74, Issue 2, pp. 211–217). Blackwell Publishing Ltd. https://doi.org/10.1111/gfs.12429Julon, D., Puicón, V., Chávez, A., Bardales, W., Gonzales, J., Vásquez, H., Maicelo, J. (2020). Prevalence of Fasciola hepatica and gastrointestinal parasites in bovine of the Amazonas Region, Peru. Revista de Investigaciones Veterinarias Del Peru, 31(1). https://doi.org/10.15381/rivep.v31i1.17560Kahl, A., Samson-Himmelstjerna, G. von, Krücken, J., Ganter, M. (2021). Chronic wasting due to liver and rumen flukes in sheep. In Animals. 11(2): 1–20. https://doi.org/10.3390/ani11020549Kain, D., Mukkala, A. N., Boggild, A. K. (2018). Prolonged antibiotic use leading to Clostridium difficile colitis in an ill returned traveller with acute fascioliasis. Journal of Travel Medicine, 25(1). https://doi.org/10.1093/jtm/tay012Kamaludeen, J., Graham-Brown, J., Stephens, N., Miller, J., Howell, A., Beesley, N. J., Hodgkinson, J., Learmount, J., Williams, D. (2019). Lack of efficacy of triclabendazole against Fasciola hepatica is present on sheep farms in three regions of England, and Wales. Veterinary Record, 184(16). https://doi.org/10.1136/vr.105209Kelley, J. M., Elliott, T. P., Beddoe, T., Anderson, G., Skuce, P., & Spithill, T. W. (2016). Current Threat of Triclabendazole Resistance in Fasciola hepatica. In Trends in Parasitology (Vol. 32, Issue 6, pp. 458–469). https://doi.org/10.1016/j.pt.2016.03.002Khanjari, A., Bahonar, A., Fallah, S., Bagheri, M., Alizadeh, A., Fallah, M., Khanjari, Z. (2014a). Prevalence of fasciolosis and dicrocoeliosis in slaughtered sheep and goats in Amol Abattoir, Mazandaran, northern Iran. Asian Pacific Journal of Tropical Disease, 4(2), 120–124. https://doi.org/10.1016/S2222-1808(14)60327-3Knubben-Schweizer, G., Torgerson, P. R. (2015). Bovine fasciolosis: Control strategies based on the location of Galba truncatula habitats on farms. Veterinary Parasitology, 208(1–2), 77–83. https://doi.org/10.1016/j.vetpar.2014.12.019Lalrinkima, H., Lalchhandama, C., Jacob, S. S., Raina, O. K., Lallianchhunga, M. C. (2021). Fasciolosis in India: An overview. In Experimental Parasitology. 222. https://doi.org/10.1016/j.exppara.2021.108066Lamb, J., Doyle, E., Barwick, J., Chambers, M., Kahn, L. (2021). Prevalence and gross pathology of liver fluke in macropods cohabiting livestock farms in north eastern NSW, Australia, and diagnosis using cELISA. International Journal for Parasitology: Parasites and Wildlife, 16, 199–207. https://doi.org/10.1016/j.ijppaw.2021.10.006Liba, J. W., Atsanda, N. N., & Francis, M. I. (2017). Economic loss from liver condemnation due to Fasciolosis in slaughtered ruminants in Maiduguri abattoir, Borno State, Nigeria. Journal of Advanced Veterinary and Animal Research, 4(1), 65–70. https://doi.org/10.5455/javar.2017.d192López-Villacís, I. C., Artieda-Rojas, J. R., Mera-Andrade, R. I., Muñoz-Espinoza, M. S., Rivera-Guerra, V. E., Cuadrado-Guevara, A. C., Zurita-Vásquez, J. H., & Montero-Recalde, M. A. (2017). Fasciola hepática: aspectos relevantes en la salud animal. J Selva And Anim Sci, 4(2), 137–146.María Díaz-Anaya, A., Chavarro-Tulcán, G. I., Pulido-Medellín, O., García-Corredor, D., Vargas-Avella, J. C. (2017). Coproparasitological study in grazing sheep in Boyacá, Colombia. In Rev. Salud Anim. 39(1).Martínez-Moreno A, Jimenez-Luque, Moreno T, Redondo E, Martín de las Mulas J, Pérez J. (1999). Liver pathology and immune response in experimental Fasciola hepatica infections of goats. Veterinary Parasitology, 82, 19–33.Mas-Coma, S., Agramunt, V. H., Valero, M. A. (2013). Direct and indirect affection of the central nervous system by Fasciola infection. In Handbook of Clinical Neurology (Vol. 114, pp. 297–310). https://doi.org/10.1016/B978-0-444-53490-3.00024-8Mas-Coma, S., Agramunt, V. H., Valero, M. A. (2014). Neurological and Ocular Fascioliasis in Humans. In Advances in Parasitology. 84: 27–149. Academic Press. https://doi.org/10.1016/B978-0-12-800099-1.00002-8Mensur S, Ansuar I, Tesfaye A, Abdulkaf K, Ahmed Y. (2016). Small ruminant fasciolosis and its economic impact in an export abattoir of Ethiopia. Livestock Research for Rural Development, 28.Micic, D., Oto, A., Charlton, M. R., Benoit, J.-L., & Siegler, M. (2020). Hiding in the Water. New England Journal of Medicine, 382(19), 1844–1849. https://doi.org/10.1056/nejmcps1902741Montero, A. B., Rodríguez, I. S., Veirano, G. S., Geldhof, P., Rendón, D. Z. (2020). Prevalencia y carga parasitaria mensual de nematodos gastrointestinales y Fasciola hepatica en bovinos lecheros de dos distritos del Valle del Mantaro, Junín, Perú. Revista de Investigaciones Veterinarias Del Peru, 31(2). https://doi.org/10.15381/rivep.v31i2.17819Morphological and molecular study of Fasciola spp. in sheep in Alkut city. (2019). International Journal of Biosciences (IJB), 14(01), 121–130. https://doi.org/10.12692/ijb/14.1.121-130Muhammad Inuwa Adamu, Abba Haruna Adamu, & Najibullah Bakari Ado. (2022). The Prevalence of Fasciola hepatica in Slaughtered Goats and Sheep (A Case Study of Potiskum Abattoir). Network for Research and Development in Africa, 12(5), 55–61. http://www.arcnjournals.org/images/NRDA-IJPASR-12-5-6.pdfNajjari, M., Karimazar, M. R., Rezaeian, S., Ebrahimipour, M., Faridi, A. (2020). Prevalence and economic impact of cystic echinococcosis and liver fluke infections in slaughtered sheep and goat in north-central Iran, 2008–2018. Journal of Parasitic Diseases, 44(1), 17–24. https://doi.org/10.1007/s12639-019-01156-wNavarro, M. A., Uzal, F. A. (2020). Pathobiology and diagnosis of clostridial hepatitis in animals. Journal of Veterinary Diagnostic Investigation, 32(2), 192–202. https://doi.org/10.1177/1040638719886567Nyindo, M., Lukambagire, A. H. (2015). Fascioliasis: An Ongoing Zoonotic Trematode Infection. In BioMed Research International. https://doi.org/10.1155/2015/786195Nyirenda, S. S., Sakala, M., Moonde, L., Kayesa, E., Fandamu, P., Banda, F., Sinkala, Y. (2019). Prevalence of bovine Fascioliasis and economic impact associated with liver condemnation in abattoirs in Mongu district of Zambia. BMC Veterinary Research, 15(1). https://doi.org/10.1186/s12917-019-1777-0Odeniran, P. O., Omolabi, K. F., Ademola, I. O. (2021). Economic impact assessment of small ruminant Fasciolosis in Nigeria using pooled prevalence obtained from literature and field epidemiological data. Veterinary Parasitology: Regional Studies and Reports, 24. https://doi.org/10.1016/j.vprsr.2021.100548Oljira, W., Mideksa, B., Mekonnen, G., Kebebew, G., Jorga, E. (2022). Fasciolosis in sheep and goats slaughtered at abattoirs in Central Ethiopia and associated financial losses. Food and Waterborne Parasitology, 28, e00173. https://doi.org/10.1016/j.fawpar.2022.e00173OPS., OMS. (2017). Manual Veterinario de Toma y Envío de Muestras. http://www.agricultura.gov.br/Ormea, V., Gotuzzo, E. (2018). The «one health» approach in Perú. Revista Peruana de Medicina Experimental y Salud Publica, 35(4), 663–666. https://doi.org/10.17843/rpmesp.2018.354.4089Ortiz-Pineda, M. C., Archila-Barrera, O. A., Bulla-Castañeda, D. M., Díaz-Anaya, A. M., Forero, J. C. G., Garcia-Corredor, D. J., Pulido-Medellín, M. O. (2021). Post mortem diagnosis of Fasciola hepatica in cattle slaughtered at the Sogamoso, Boyacá processing plant (Boyacá, Colombia). Revista de Investigaciones Veterinarias Del Peru, 32(5). https://doi.org/10.15381/rivep.v32i5.21341Owiny, M. O., Obonyo, M. O., Gatongi, P. M., Fèvre, E. M. (2019). Prevalence and spatial distribution of trematode cercariae in vector snails within different agro-ecological zones in Western Kenya, 2016. Pan African Medical Journal, 32. https://doi.org/10.11604/pamj.2019.32.142.14418Palacio, S., Bertor, J., Beltrao, M., Vázquez, A., Ortiz, R., Varona, M. (2019). Economic losses induced by Fasciola hepatica in cattle slaughtered in Chacuba slaughterhouse, Camagüey, Cuba. Cuban Journal of Agricultural Science, 53(1), 35–39.Pedroso, R. C. da C., Cunha, S. N. da, Cunha-Neto, A. da. (2020). Helmintos de importância para saúde pública em alfaces no Brasil: uma revisão sistemática/ Helminths of public health importance in lettuce in Brazil: a systematic review. Brazilian Journal of Health Review, 3(6), 19200–19225. https://doi.org/10.34119/bjhrv3n6-304Piedrafita, D., Spithill, T. W., Smith, R. E., Raadsma, H. W. (2010). Improving animal and human health through understanding liver fluke immunology. In Parasite Immunology. 32(8): 572–581. https://doi.org/10.1111/j.1365-3024.2010.01223.xPinilla, J., Muñoz, A., Uribe, N. (2020). Prevalence and risk factors associated with liver fluke Fasciola hepatica in cattle and sheep in three municipalities in the Colombian Northeastern Mountains. Veterinary Parasitology: Regional Studies and Reports, 19. https://doi.org/10.1016/j.vprsr.2019.100364Pinilla León, J. C., Delgado, N. U., Florez, A. A. (2019). Prevalence of gastrointestinal parasites in cattle and sheep in three municipalities in the Colombian Northeastern Mountain. Veterinary World, 12(1), 48–54. https://doi.org/10.14202/vetworld.2019.48-54Pulido-Medellín, M. O., Chavarro-Tulcán, G. I., & Díaz-Anaya, A. M. (2020). Prevalence and risk factors of gastrointestinal parasites in sheep from Ubaté, Cundinamarca, Colombia. Revista Brasileira de Medicina Veterinaria, 42(1). https://doi.org/10.29374/2527-2179.BJVM098819Qureshi, A. W., Zeb, A., Mansoor, A., Hayat, A., & Mas-Coma, S. (2019). Fasciola hepatica infection in children actively detected in a survey in rural areas of Mardan district, Khyber Pakhtunkhawa province, northern Pakistan. Parasitology International, 69, 39–46. https://doi.org/10.1016/j.parint.2018.11.003Rashid, M., Rashid, M. I., Akbar, H., Ahmad, L., Hassan, M. A., Ashraf, K., Saeed, K., Gharbi, M. (2019). A systematic review on modelling approaches for economic losses studies caused by parasites and their associated diseases in cattle. In Parasitology. 146(2): 129–141). https://doi.org/10.1017/S0031182018001282Rassol, A. M., Ahmed, A. M., Sobhy, H. M., Abdelgayed, S. S., Hekal, S. H. (2020). Effects of Fascioliasis on the Economic Losses of Beef Liver at Abu Simbel Abattoir, Aswan Governorate, Egypt. Advances in Animal and Veterinary Sciences, 8(11), 1175–1179. https://doi.org/10.17582/journal.aavs/2020/8.11.1175.1179Recalde-Reyes, D. P., Padilla, L., Giraldo, M. I., Segovia, L. J., González, M. M., Osorio, J. C. (2014). Prevalence of Fasciola hepatica in humans and cattle in the department of Quindio-Colombia 2012-2013. Infectio, 18(4), 153–157. https://doi.org/10.1016/j.infect.2014.09.001Robaina, E. R. C., Álvarez Escobar, C. M., Torres, A., Semper, A. I. (2020). Hepatic fasciolosis, a series of cases reported in Matanzas, Cuba. https://orcid.org/0000-0002-7932-9401Ruhoollah, Khan, W., Al-Jabr, O. A., Khan, T., Khan, A., El-Ghareeb, W. R., Aguilar-Marcelino, L., Hussein, E. O. S., Alhimaidi, A. R., Swelum, A. A. (2023). Prevalence of gastrointestinal parasite in small ruminants of District Dir Upper Khyber Pakhtunkhwa Province of Pakistan. Brazilian Journal of Biology, 83. https://doi.org/10.1590/1519-6984.248978Ruiz-Campillo, M. T., Molina-Hernandez, V., Escamilla, A., Stevenson, M., Perez, J., Martinez-Moreno, A., Donnelly, S., Dalton, J. P., Cwiklinski, K. (2017). Immune signatures of pathogenesis in the peritoneal compartment during early infection of sheep with Fasciola hepatica. Scientific Reports, 7(1). https://doi.org/10.1038/s41598-017-03094-0Sarkari, B., & Khabisi, S. A. (2017). Immunodiagnosis of human Fascioliasis: An update of concepts and performances of the serological assays. In Journal of Clinical and Diagnostic Research. 11(6):05-10. https://doi.org/10.7860/JCDR/2017/26066.10086Sharma, K. (2020). Gastrointestinal Helminthic Challenges in Sheep and Goats in Afro-Asian Region: A Review. Journal of Animal Research, 10(1). https://doi.org/10.30954/2277-940x.01.2020.1Shrestha, S., Barratt, A., Fox, N. J., Vosough Ahmadi, B., Hutchings, M. R. (2020). Financial Impacts of Liver Fluke on Livestock Farms Under Climate Change–A Farm Level Assessment. Frontiers in Veterinary Science, 7. https://doi.org/10.3389/fvets.2020.564795Siles-Lucas, M., Becerro-Recio, D., Serrat, J., González-Miguel, J. (2021). Fascioliasis and Fasciolopsiasis: Current knowledge and future trends. In Research in Veterinary Science. 134:27–35. https://doi.org/10.1016/j.rvsc.2020.10.011Silva, A. E. P., Freitas, C. da C., Dutra, L. V., Molento, M. B. (2020). Correlation between climate data and land altitude for Fasciola hepatica infection in cattle in Santa Catarina, Brazil. Revista Brasileira de Parasitologia Veterinaria, 29(3), 1–7. https://doi.org/10.1590/s1984-29612020065Singh, D. K., Singh, V. K., Singh, R. N., Kumar, P. (2021). Fasciolosis: Causes, Challenges and Controls. Springer Singapore. https://doi.org/10.1007/978-981-16-0259-7Soosaraei, M., Fakhar, M., Teshnizi, S. H., Emameh, R. Z., Hezarjaribi, H. Z., Asfaram, S., Faridnia, R., Kalani, H. (2020). Status of Fasciolosis among domestic ruminants in Iran based on abattoir data: a systematic review and meta-analysis. Annals of Parasitology, 66(1). https://doi.org/10.17420/ap6601.240Spithill, T. W., Piedrafitat, D., Smooker, P. M. (1997). Immunological Approaches for the Control of Fasciolosis. In Australian Society for Parasitology. 27:10.Squire, S. A., Yang, R., Robertson, I., Ayi, I., Squire, D. S., Ryan, U. (2018). Gastrointestinal helminths in farmers and their ruminant livestock from the Coastal Savannah zone of Ghana. Parasitology Research, 117(10), 3183–3194. https://doi.org/10.1007/s00436-018-6017-1Sripa, B., Echaubard, P. (2017). Prospects and Challenges towards Sustainable Liver Fluke Control. In Trends in Parasitology. 33(10): 799–812. https://doi.org/10.1016/j.pt.2017.06.002Sugiyama, T., Ichikawa-Seki, M., Sato, H., Kounosu, A., Tanaka, M., Maruyama, H. (2021). Enzyme-linked immunosorbent assay (ELISA) using recombinant Fasciola cathepsin L1 for the diagnosis of human fasciolosis caused by Fasciola hepatica/gigantica hybrid type. Parasitology International, 82. https://doi.org/10.1016/j.parint.2021.102311Tadesse, A., Usman, J. (2022). Status of small ruminant Fasciolosis and diagnostic test evaluation at Haramaya town municipal abattoir, East Harrarghe Zone, Ethiopia. Ethiopian Veterinary Journal, 26(1), 82–104. https://doi.org/10.4314/evj.v26i1.6Taghipour, A., Zaki, L., Rostami, A., Foroutan, M., Ghaffarifar, F., Fathi, A., Abdoli, A. (2019). Highlights of human ectopic fascioliasis: a systematic review. In Infectious Diseases. 51(11–12):785–792. https://doi.org/10.1080/23744235.2019.1663362Tidman, R., Abela-Ridder, B., De Castañeda, R. R. (2021). The impact of climate change on neglected tropical diseases: A systematic review. In Transactions of the Royal Society of Tropical Medicine and Hygiene. 115(2):147–168. https://doi.org/10.1093/trstmh/traa192Torrel, S., Vásquez, D., Moncada, R., Coronado, F., Aguilar, N., García, T., Castro, D. (2020). Ectopic Fasciola hepatica in lung of slaughtered cattle in the municipal abattoir of Cajamarca, Peru. Revista de Investigaciones Veterinarias Del Peru, 31(3). https://doi.org/10.15381/RIVEP.V31I3.18721Tran, D. H., Hung, H. T. T. (2020). Detecting Fasciola hepatica and Fasciola gigantica microRNAs with loop-mediated isothermal amplification (LAMP). Journal of Parasitic Diseases, 44(2), 364–373. https://doi.org/10.1007/s12639-019-01164-wTsega, M., Dereso, S., Getu, A. (2015). A Review on Ruminant Fasciolosis. OALib, 02(08), 1–8. https://doi.org/10.4236/oalib.1101655Tsegaye, G., & Abebe, K. (2021). A Review on Bovine Fasciolosis. Global Veterinaria, 23(3), 134–141. https://doi.org/10.5829/idosi.gv.2021.134.141Uribe, N., Becerra, W. M., & Velásquez, L. E. (2014). Lymnaea cousini, huésped de Fasciola hepatica en el trópico alto andino de Colombia, y sus nuevos haplotipos, confirmados con el marcador mitocondrial del gen del citocromo oxidasa I. Biomedica, 34(4), 598–604. https://doi.org/10.7705/biomedica.v34i4.2312Uruburu, M., Bedoya, J., Velásquez, L. (2013). ELISA indirecta para el diagnóstico de Fasciolosis bovina en leche. Rev CES Med Vet Zoot, 8(2), 93–100. https://doi.org/10.21615/2850Valderrama, A. (2016). Prevalencia de Fascioliasis en animales poligástricos de Perú, 1985-2015. Revista de Medicina Veterinaria, 32, 121. https://doi.org/10.19052/mv.3861Valero, M. A., Pérez-Crespo, I., Khoubbane, M., Artigas, P., Panova, M., Ortiz, P., Maco, V., Espinoza, J. R., & Mas-Coma, S. (2012). Fasciola hepatica phenotypic characterization in Andean human endemic areas: Valley versus altiplanic patterns analysed in liver flukes from sheep from Cajamarca and Mantaro, Peru. Infection, Genetics and Evolution, 12(2), 403–410. https://doi.org/10.1016/j.meegid.2012.01.009Vázquez, A. A., Alba, A., Alda, P., Vittecoq, M., & Hurtrez-Boussès, S. (2022). On the arrival of fasciolosis in the Americas. In Trends in Parasitology. 38(3):195–204. https://doi.org/10.1016/j.pt.2021.12.001Vineer, H., Morgan, E. R., Hertzberg, H., Bartley, D. J., Bosco, A., Charlier, J., Chartier, C., Claerebout, E., de Waal, T., Hendrickx, G., Hinney, B., Höglund, J., Jez Ek, J. I., Kašný, M., Keane, O. M., Martínez-Valladares, M., Mateus, T. L., McIntyre, J., Mickiewicz, M., … Rinaldi, L. (2020). Increasing importance of anthelmintic resistance in European livestock: Creation and meta-analysis of an open database. Parasite, 27. https://doi.org/10.1051/parasite/2020062VSierra, R., Martínez, R. A., Gutiérrez, R., Dolores, C., Uribe, N. (2017a). Estandarización de ELISA para el diagnóstico de Fasciolosis bovina, ovina y humana. Revista de La Universidad Industrial de Santander. Salud, 49(4), 549–556. https://doi.org/10.18273/revsal.v49n4-2017004Wu, Z., Wang, J., Meng, Z., Jin, W., He, K., Zhang, W., Di, W. (2021). Identification of Fasciola spp. based on ITS-2 reveals the Fasciola gigantica infection in buffaloes in Nanning city, South China. Veterinary Parasitology, 300, 109585. https://doi.org/10.1016/j.vetpar.2021.109585Zafar, A., Khan, M. K., Ud Din Sindhu, Z., Abbas, R. Z., Masood, S., Abbas, Z., Mahmood, M. S., Saleemi, M. K., Khan, J. A., Hussain, R., Naseer, M. U., Iqbal, Z., Javed, H. (2019). Seroprevalence of Fasciola hepatica in small ruminants of District Chakwal, Punjab, Pakistan. Pakistan Veterinary Journal, 39(1), 96–100. https://doi.org/10.29261/pakvetj/2018.024Zeng, M., Wang, X., Lan, Z., Guo, X., Jiang, Y., Wu, T., Chang, Q., Wang, C. (2022). Identification of new polymorphic positions in rDNA sequences of the “intermediate” Fasciola forms. Parasitology International. 88, 102555. https://doi.org/10.1016/j.parint.2022.102555Zerna, G., Spithill, T. W., & Beddoe, T. (2021). Current status for controlling the overlooked caprine fasciolosis. Animals. 11(6). https://doi.org/10.3390/ani11061819Zewde, A., Bayu, Y., Wondimu, A. (2019). Prevalence of Bovine Fasciolosis and Its Economic Loss due to Liver Condemnation at Wolaita Sodo Municipal Abattair, Ethiopia. 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