Epidemiological, Clinical and Diagnostic Features of FeLV and FIV: An Updated Review

Feline leukemia (FeLV) and immunodeficiency (FIV) viruses are pathogens which affect domestic cats and are classified within the Retroviridae family. These feline retroviruses feature a high capacity of mutation and recombination, which derives in a broad population of viral subtypes with variable p...

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Tipo de recurso:
Fecha de publicación:
2019
Institución:
Universidad Pedagógica y Tecnológica de Colombia
Repositorio:
RiUPTC: Repositorio Institucional UPTC
Idioma:
spa
OAI Identifier:
oai:repositorio.uptc.edu.co:001/10629
Acceso en línea:
https://revistas.uptc.edu.co/index.php/ciencia_agricultura/article/view/9119
https://repositorio.uptc.edu.co/handle/001/10629
Palabra clave:
cats
diagnosis
feline immunodeficiency virus
feline leukemia virus
prevalence
diagnóstico
gatos
patogenia
prevalencia
virus de la inmunodeficiencia felina
virus de la leucemia felina
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License
http://purl.org/coar/access_right/c_abf2
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oai_identifier_str oai:repositorio.uptc.edu.co:001/10629
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network_name_str RiUPTC: Repositorio Institucional UPTC
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dc.title.en-US.fl_str_mv Epidemiological, Clinical and Diagnostic Features of FeLV and FIV: An Updated Review
dc.title.es-ES.fl_str_mv Aspectos epidemiológicos, clínicos y de diagnóstico del ViLeF y VIF: una revisión actualizada
title Epidemiological, Clinical and Diagnostic Features of FeLV and FIV: An Updated Review
spellingShingle Epidemiological, Clinical and Diagnostic Features of FeLV and FIV: An Updated Review
cats
diagnosis
feline immunodeficiency virus
feline leukemia virus
prevalence
diagnóstico
gatos
patogenia
prevalencia
virus de la inmunodeficiencia felina
virus de la leucemia felina
title_short Epidemiological, Clinical and Diagnostic Features of FeLV and FIV: An Updated Review
title_full Epidemiological, Clinical and Diagnostic Features of FeLV and FIV: An Updated Review
title_fullStr Epidemiological, Clinical and Diagnostic Features of FeLV and FIV: An Updated Review
title_full_unstemmed Epidemiological, Clinical and Diagnostic Features of FeLV and FIV: An Updated Review
title_sort Epidemiological, Clinical and Diagnostic Features of FeLV and FIV: An Updated Review
dc.subject.en-US.fl_str_mv cats
diagnosis
feline immunodeficiency virus
feline leukemia virus
prevalence
topic cats
diagnosis
feline immunodeficiency virus
feline leukemia virus
prevalence
diagnóstico
gatos
patogenia
prevalencia
virus de la inmunodeficiencia felina
virus de la leucemia felina
dc.subject.es-ES.fl_str_mv diagnóstico
gatos
patogenia
prevalencia
virus de la inmunodeficiencia felina
virus de la leucemia felina
description Feline leukemia (FeLV) and immunodeficiency (FIV) viruses are pathogens which affect domestic cats and are classified within the Retroviridae family. These feline retroviruses feature a high capacity of mutation and recombination, which derives in a broad population of viral subtypes with variable pathogenic capacity. These viruses are of great importance in feline health, not only because of the severity of the clinical signs in patients, but also due to the diagnostic complexity which they can pose. The range of prevalence is wide among different studies and geographical zones, probably due to the influence of risk factors, clinical condition of cats and diagnostic tests used. The clinical signs of FeLV disease are variable, depending on the viral subtype and the host’s immune-compromise, as there could be lymphoma, leukemia, red cell aplasia myelosuppresion and immunodeficiency. On another hand, FIV has a marked tropism towards TCD4+ lymphocytes, triggering a characteristic immunodeficiency, but a frequent neurotropism has also been described. In both viruses, serological diagnostic is a routine procedure; however, in some situations it is not possible to identify correctly the infected cats. Recent studies have included Polymerase Chain Reaction (PCR) as a diagnostic method, opening a possibility to decreasing diagnostic errors for FeLV, but its effectiveness for FIV detection is still being discussed. The purpose of the present article is to provide updated and precise information about epidemiological, clinical and diagnostic aspects of FeLV and FIV in domestic cats.
publishDate 2019
dc.date.accessioned.none.fl_str_mv 2024-07-05T18:11:35Z
dc.date.available.none.fl_str_mv 2024-07-05T18:11:35Z
dc.date.none.fl_str_mv 2019-05-01
dc.type.none.fl_str_mv info:eu-repo/semantics/article
dc.type.en-US.fl_str_mv research
dc.type.es-ES.fl_str_mv investigación
dc.type.coarversion.fl_str_mv http://purl.org/coar/version/c_970fb48d4fbd8a85
dc.type.coar.fl_str_mv http://purl.org/coar/resource_type/c_2df8fbb1
dc.identifier.none.fl_str_mv https://revistas.uptc.edu.co/index.php/ciencia_agricultura/article/view/9119
10.19053/01228420.v16.n2.2019.9119
dc.identifier.uri.none.fl_str_mv https://repositorio.uptc.edu.co/handle/001/10629
url https://revistas.uptc.edu.co/index.php/ciencia_agricultura/article/view/9119
https://repositorio.uptc.edu.co/handle/001/10629
identifier_str_mv 10.19053/01228420.v16.n2.2019.9119
dc.language.none.fl_str_mv spa
dc.language.iso.none.fl_str_mv spa
language spa
dc.relation.none.fl_str_mv https://revistas.uptc.edu.co/index.php/ciencia_agricultura/article/view/9119/7621
https://revistas.uptc.edu.co/index.php/ciencia_agricultura/article/view/9119/7843
https://revistas.uptc.edu.co/index.php/ciencia_agricultura/article/view/9119/7921
dc.rights.coar.fl_str_mv http://purl.org/coar/access_right/c_abf2
rights_invalid_str_mv http://purl.org/coar/access_right/c_abf2
dc.format.none.fl_str_mv application/pdf
application/xml
dc.coverage.en-US.fl_str_mv N.A.
dc.coverage.es-ES.fl_str_mv N.A.
dc.publisher.en-US.fl_str_mv Universidad Pedagógica y Tecnológica de Colombia
dc.source.en-US.fl_str_mv Ciencia y Agricultura; Vol. 16 No. 2 (2019); 57-77
dc.source.es-ES.fl_str_mv Ciencia y Agricultura; Vol. 16 Núm. 2 (2019); 57-77
dc.source.none.fl_str_mv 2539-0899
institution Universidad Pedagógica y Tecnológica de Colombia
repository.name.fl_str_mv Repositorio Institucional UPTC
repository.mail.fl_str_mv repositorio.uptc@uptc.edu.co
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spelling 2019-05-012024-07-05T18:11:35Z2024-07-05T18:11:35Zhttps://revistas.uptc.edu.co/index.php/ciencia_agricultura/article/view/911910.19053/01228420.v16.n2.2019.9119https://repositorio.uptc.edu.co/handle/001/10629Feline leukemia (FeLV) and immunodeficiency (FIV) viruses are pathogens which affect domestic cats and are classified within the Retroviridae family. These feline retroviruses feature a high capacity of mutation and recombination, which derives in a broad population of viral subtypes with variable pathogenic capacity. These viruses are of great importance in feline health, not only because of the severity of the clinical signs in patients, but also due to the diagnostic complexity which they can pose. The range of prevalence is wide among different studies and geographical zones, probably due to the influence of risk factors, clinical condition of cats and diagnostic tests used. The clinical signs of FeLV disease are variable, depending on the viral subtype and the host’s immune-compromise, as there could be lymphoma, leukemia, red cell aplasia myelosuppresion and immunodeficiency. On another hand, FIV has a marked tropism towards TCD4+ lymphocytes, triggering a characteristic immunodeficiency, but a frequent neurotropism has also been described. In both viruses, serological diagnostic is a routine procedure; however, in some situations it is not possible to identify correctly the infected cats. Recent studies have included Polymerase Chain Reaction (PCR) as a diagnostic method, opening a possibility to decreasing diagnostic errors for FeLV, but its effectiveness for FIV detection is still being discussed. The purpose of the present article is to provide updated and precise information about epidemiological, clinical and diagnostic aspects of FeLV and FIV in domestic cats.Los virus de la leucemia felina (ViLeF) e inmunodeficiencia felina (VIF) están clasificados dentro de la familia Retroviridae y son patógenos que afectan a los gatos domésticos. Estos retrovirus felinos tienen alta capacidad de mutación y recombinación, lo cual favorece una amplia población de subtipos virales con capacidades patogénicas diferentes. Tienen gran relevancia en la salud felina, no solo por la severidad de las manifestaciones clínicas en los pacientes, sino también por la complejidad diagnóstica que pueden representar. El rango de prevalencias es amplio entre distintos estudios y zonas geográficas, probablemente por influencia de los factores de riesgo, las condiciones clínicas de los gatos y las pruebas diagnósticas utilizadas. Las manifestaciones clínicas de la patogenia del ViLeF son variables, dependiendo del subtipo viral y del inmunocompromiso del hospedero, ya que pueden existir linfomas, leucemias, aplasia eritrocitaria, mielosupresión e inmunodeficiencia. Por otro lado, el VIF tiene un marcado tropismo hacia los linfocitos TCD4+, lo cual desencadena una inmunodeficiencia característica, pero también se ha descrito un frecuente neurotropismo. Para ambos virus, el diagnóstico de rutina es de tipo serológico, sin embargo, en algunas situaciones no es posible identificar correctamente a los gatos infectados. En estudios recientes se ha incluido el diagnóstico de estos virus por medio de la reacción en cadena de la polimerasa (PCR), lo que abre una posibilidad a la disminución de errores diagnósticos para el ViLeF, pero aún se discute su efectividad para la detección del VIF. El objetivo del presente artículo es proporcionar información actualizada y precisa sobre los aspectos epidemiológicos, clínicos y de diagnóstico del ViLeF y VIF en gatos domésticosapplication/pdfapplication/xmlspaspaUniversidad Pedagógica y Tecnológica de Colombiahttps://revistas.uptc.edu.co/index.php/ciencia_agricultura/article/view/9119/7621https://revistas.uptc.edu.co/index.php/ciencia_agricultura/article/view/9119/7843https://revistas.uptc.edu.co/index.php/ciencia_agricultura/article/view/9119/7921Ciencia y Agricultura; Vol. 16 No. 2 (2019); 57-77Ciencia y Agricultura; Vol. 16 Núm. 2 (2019); 57-772539-0899catsdiagnosisfeline immunodeficiency virusfeline leukemia virusprevalencediagnósticogatospatogeniaprevalenciavirus de la inmunodeficiencia felinavirus de la leucemia felinaEpidemiological, Clinical and Diagnostic Features of FeLV and FIV: An Updated ReviewAspectos epidemiológicos, clínicos y de diagnóstico del ViLeF y VIF: una revisión actualizadainfo:eu-repo/semantics/articleresearchinvestigaciónhttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_2df8fbb1N.A.N.A.http://purl.org/coar/access_right/c_abf2Canto-Valdés, María CasandraBolio-González, Manuel EmilioRamírez-Álvarez, HugoCen Cen, Carlos Josué001/10629oai:repositorio.uptc.edu.co:001/106292025-07-18 11:01:29.44metadata.onlyhttps://repositorio.uptc.edu.coRepositorio Institucional UPTCrepositorio.uptc@uptc.edu.co