Prefrontal cortex involvement during dual-task stair climbing in healthy older adults: An fNIRS study

Executive function and motor control deficits adversely affect gait performance with age, but the neural correlates underlying this interaction during stair climbing remains unclear. Twenty older adults (72.7 ± 6.9 years) completed single tasks: standing and responding to a response time task (SC),...

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Fecha de publicación:: 2021

Institución:: Universidad de Medellín

Repositorio:: Repositorio UDEM

Idioma:: eng

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repository_id_str
dc.title.none.fl_str_mv	Prefrontal cortex involvement during dual-task stair climbing in healthy older adults: An fNIRS study
title	Prefrontal cortex involvement during dual-task stair climbing in healthy older adults: An fNIRS study
spellingShingle	Prefrontal cortex involvement during dual-task stair climbing in healthy older adults: An fNIRS study Cognitive aging Cognitive function Executive function Functional near-infrared spectroscopy (fNIRS) Gait Neuroimaging Older adult Prefrontal cortex (PFC) Stair climbing aged article cognitive aging controlled study executive function female functional near-infrared spectroscopy hemodynamics human human experiment male neuroimaging prefrontal cortex reaction time stair climbing walking speed
title_short	Prefrontal cortex involvement during dual-task stair climbing in healthy older adults: An fNIRS study
title_full	Prefrontal cortex involvement during dual-task stair climbing in healthy older adults: An fNIRS study
title_fullStr	Prefrontal cortex involvement during dual-task stair climbing in healthy older adults: An fNIRS study
title_full_unstemmed	Prefrontal cortex involvement during dual-task stair climbing in healthy older adults: An fNIRS study
title_sort	Prefrontal cortex involvement during dual-task stair climbing in healthy older adults: An fNIRS study
dc.subject.spa.fl_str_mv	Cognitive aging Cognitive function Executive function Functional near-infrared spectroscopy (fNIRS) Gait Neuroimaging Older adult Prefrontal cortex (PFC) Stair climbing
topic	Cognitive aging Cognitive function Executive function Functional near-infrared spectroscopy (fNIRS) Gait Neuroimaging Older adult Prefrontal cortex (PFC) Stair climbing aged article cognitive aging controlled study executive function female functional near-infrared spectroscopy hemodynamics human human experiment male neuroimaging prefrontal cortex reaction time stair climbing walking speed
dc.subject.keyword.eng.fl_str_mv	aged article cognitive aging controlled study executive function female functional near-infrared spectroscopy hemodynamics human human experiment male neuroimaging prefrontal cortex reaction time stair climbing walking speed
description	Executive function and motor control deficits adversely affect gait performance with age, but the neural correlates underlying this interaction during stair climbing remains unclear. Twenty older adults (72.7 ± 6.9 years) completed single tasks: standing and responding to a response time task (SC), ascending or descending stairs (SMup, SMdown); and a dual-task: responding while ascending or descending stairs (DTup, DTdown). Prefrontal hemodynamic response changes (∆HbO2, ∆HbR) were examined using functional near-infrared spectroscopy (fNIRS), gait speed was measured using in-shoe smart insoles, and vocal response time and accuracy were recorded. Findings revealed increased ∆HbO2 (p = 0.020) and slower response times (p < 0.001) during dual-versus single tasks. ∆HbR (p = 0.549), accuracy (p = 0.135) and gait speed (p = 0.475) were not significantly different between tasks or stair climbing conditions. ∆HbO2 and response time findings suggest that executive processes are less efficient during dual-tasks. These findings, in addition to gait speed and accuracy maintenance, may provide insights into the neural changes that precede performance declines. To capture the subtle differences between stair ascent and descent and extend our understanding of the neural correlates of stair climbing in older adults, future studies should examine more difficult cognitive tasks. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.
publishDate	2021
dc.date.accessioned.none.fl_str_mv	2021-02-05T14:57:39Z
dc.date.available.none.fl_str_mv	2021-02-05T14:57:39Z
dc.date.none.fl_str_mv	2021
dc.type.eng.fl_str_mv	Article
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dc.type.driver.none.fl_str_mv	info:eu-repo/semantics/article
dc.identifier.issn.none.fl_str_mv	20763425
dc.identifier.uri.none.fl_str_mv	http://hdl.handle.net/11407/5898
dc.identifier.doi.none.fl_str_mv	10.3390/brainsci11010071
identifier_str_mv	20763425 10.3390/brainsci11010071
url	http://hdl.handle.net/11407/5898
dc.language.iso.none.fl_str_mv	eng
language	eng
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dc.relation.citationvolume.none.fl_str_mv	11
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dc.relation.citationstartpage.none.fl_str_mv	1
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dc.relation.references.none.fl_str_mv	Jacobs, J.V., A Review of Stairway Falls and Stair Negotiation: Lessons Learned and Future Needs to Reduce Injury (2016) Gait Posture, 49, pp. 159-167. , [CrossRef] [PubMed] Beurskens, R., Bock, O., Age-Related Deficits of Dual-Task Walking: A Review (2012) Neural Plast, 2012, p. 131608. , [CrossRef] [PubMed] Raz, N., Lindenberger, U., Rodrigue, K.M., Kennedy, K.M., Head, D., Williamson, A., Dahle, C., Acker, J.D., Regional Brain Changes in Aging Healthy Adults: General Trends, Individual Differences and Modifiers (2005) Cereb. Cortex, 15, pp. 1676-1689. , [CrossRef] [PubMed] Li, K.Z.H., Bherer, L., Mirelman, A., Maidan, I., Hausdorff, J.M., Cognitive Involvement in Balance, Gait and Dual-Tasking in Aging: A Focused Review From a Neuroscience of Aging Perspective (2018) Front. Neurol, 9, p. 913. , [CrossRef] [PubMed] Yogev, G., Hausdorff, J.M., Giladi, N., The Role of Executive Function and Attention in Gait (2008) Mov. Disord. Off. J. Mov. Disord. Soc, 23, pp. 329-472. , [CrossRef] Hausdorff, J.M., Schweiger, A., Herman, T., Yogev-Seligmann, G., Giladi, N., Dual Task Decrements in Gait among Healthy Older Adults: Contributing Factors (2008) J. Gerontol. A. Biol. Sci. Med. Sci, 63, pp. 1335-1343. , [CrossRef] [PubMed] Woollacott, M., Shumway-Cook, A., Attention and the Control of Posture and Gait: A Review of an Emerging Area of Research (2002) Gait Posture, 16, pp. 1-14. , [CrossRef] Madehkhaksar, F., Egges, A., Effect of Dual Task Type on Gait and Dynamic Stability during Stair Negotiation at Different Inclinations (2016) Gait Posture, 43, pp. 114-119. , [CrossRef] Tiedemann, A.C., Sherrington, C., Lord, S.R., Physical and Psychological Factors Associated With Stair Negotiation Performance in Older People (2007) J. Gerontol. A. Biol. Sci. Med. Sci, 62, pp. 1259-1265. , [CrossRef] Lee, H.-J., Chou, L.-S., Balance Control during Stair Negotiation in Older Adults (2007) J. Biomech, 40, pp. 2530-2536. , [CrossRef] Miyasike-daSilva, V., Allard, F., McIlroy, W.E., Where Do We Look When We Walk on Stairs? Gaze Behaviour on Stairs, Transitions, and Handrails (2011) Exp. Brain Res, 209, pp. 73-83. , [CrossRef] [PubMed] Startzell, J.K., Owens, D.A., Mulfinger, L.M., Cavanagh, P.R., Stair Negotiation in Older People: A Review (2000) J. Am. Geriatr. Soc, 48, pp. 567-580. , [CrossRef] [PubMed] Hamel, K.A., Cavanagh, P.R., Stair Performance in People Aged 75 and Older (2004) J. Am. Geriatr. Soc, 52, pp. 563-567. , [CrossRef] [PubMed] Bürki, C.N., Bridenbaugh, S.A., Reinhardt, J., Stippich, C., Kressig, R.W., Blatow, M., Imaging Gait Analysis: An FMRI Dual Task Study (2017) Brain Behav, 7, p. e00724. , [CrossRef] [PubMed] Fraser, S.A., Dupuy, O., Pouliot, P., Lesage, F., Bherer, L., Comparable Cerebral Oxygenation Patterns in Younger and Older Adults during Dual-Task Walking with Increasing Load (2016) Front. 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Actuator Netw, 7, p. 36. , [CrossRef] Arafsha, F., Laamarti, F., Saddik, A.E., Development of a Wireless CPS for Gait Parameters Measurement and Analysis Proceedings of the 2018 IEEE International Instrumentation and Measurement Technology Conference (I2MTC), pp. 1-5. , Houston, TX, USA, 14–17 May 2018 Badawi, H., Laamarti, F., Arafsha, F., El Saddik, A., Standardizing a Shoe Insole Based on ISO/IEEE 11073 Personal Health Device (X73-PHD) Standards (2019) Proceedings of the Information Technology and Systems, pp. 764-778. , Rocha, Á, Ferrás, C., Paredes, M., Eds. Springer: Berlin/Heidelberg, Germany Herold, F., Wiegel, P., Scholkmann, F., Thiers, A., Hamacher, D., Schega, L., Functional Near-Infrared Spectroscopy in Movement Science: A Systematic Review on Cortical Activity in Postural and Walking Tasks (2017) Neurophotonics, 4, p. 41403. , [CrossRef] [PubMed] Brown, L.A., McKenzie, N.C., Doan, J.B., Age-Dependent Differences in the Attentional Demands of Obstacle Negotiation (2005) J. Gerontol. A. Biol. Sci. Med. Sci, 60, pp. 924-927. , [CrossRef] [PubMed] Yogev-Seligmann, G., Rotem-Galili, Y., Mirelman, A., Dickstein, R., Giladi, N., Hausdorff, J.M., How Does Explicit Prioritization Alter Walking During Dual-Task Performance? Effects of Age and Sex on Gait Speed and Variability (2010) Phys. 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Neurosci, 31, pp. 17242-17249. , [CrossRef] Czernochowski, D., NESSLER, D., FRIEDMAN, D., On Why Not to Rush Older Adults—Relying on Reactive Cognitive Control Can Effectively Reduce Errors at the Expense of Slowed Responses (2010) Psychophysiology, 47, pp. 637-646. , [CrossRef] [PubMed] Shumway-Cook, A., Woollacott, M., Kerns, K.A., Baldwin, M., The Effects of Two Types of Cognitive Tasks on Postural Stability in Older Adults With and Without a History of Falls (1997) J. Gerontol. A. Biol. Sci. Med. Sci, 52A, pp. M232-M240. , [CrossRef] [PubMed] Li, K.Z.H., Lindenberger, U., Freund, A.M., Baltes, P.B., Walking While Memorizing: Age-Related Differences in Compensatory Behavior (2001) Psychol. Sci, 12, pp. 230-237. , [CrossRef] Choi, J.-H., Galea, E.R., Hong, W.-H., Individual Stair Ascent and Descent Walk Speeds Measured in a Korean High-Rise Building (2014) Fire Technol, 50, pp. 267-295. , [CrossRef] Harada, T., Miyai, I., Suzuki, M., Kubota, K., Gait Capacity Affects Cortical Activation Patterns Related to Speed Control in the Elderly (2009) Exp. Brain Res, 193, pp. 445-454. , [CrossRef] Suzuki, M., Miyai, I., Ono, T., Kubota, K., Activities in the Frontal Cortex and Gait Performance Are Modulated by Preparation. An FNIRS Study (2008) NeuroImage, 39, pp. 600-607. , [CrossRef] [PubMed] Koenraadt, K.L.M., Roelofsen, E.G.J., Duysens, J., Keijsers, N.L.W., Cortical Control of Normal Gait and Precision Stepping: An FNIRS Study (2014) NeuroImage, 85, pp. 415-422. , [CrossRef] [PubMed]
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dc.publisher.none.fl_str_mv	MDPI AG
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dc.source.none.fl_str_mv	Brain Sciences
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spelling	20212021-02-05T14:57:39Z2021-02-05T14:57:39Z20763425http://hdl.handle.net/11407/589810.3390/brainsci11010071Executive function and motor control deficits adversely affect gait performance with age, but the neural correlates underlying this interaction during stair climbing remains unclear. Twenty older adults (72.7 ± 6.9 years) completed single tasks: standing and responding to a response time task (SC), ascending or descending stairs (SMup, SMdown); and a dual-task: responding while ascending or descending stairs (DTup, DTdown). Prefrontal hemodynamic response changes (∆HbO2, ∆HbR) were examined using functional near-infrared spectroscopy (fNIRS), gait speed was measured using in-shoe smart insoles, and vocal response time and accuracy were recorded. Findings revealed increased ∆HbO2 (p = 0.020) and slower response times (p < 0.001) during dual-versus single tasks. ∆HbR (p = 0.549), accuracy (p = 0.135) and gait speed (p = 0.475) were not significantly different between tasks or stair climbing conditions. ∆HbO2 and response time findings suggest that executive processes are less efficient during dual-tasks. These findings, in addition to gait speed and accuracy maintenance, may provide insights into the neural changes that precede performance declines. To capture the subtle differences between stair ascent and descent and extend our understanding of the neural correlates of stair climbing in older adults, future studies should examine more difficult cognitive tasks. © 2021 by the authors. Licensee MDPI, Basel, Switzerland.engMDPI AGIngeniería de SistemasFacultad de Ingenieríashttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85099388962&doi=10.3390%2fbrainsci11010071&partnerID=40&md5=9f2a8ed77da610370d7f31037fbbd180111114Jacobs, J.V., A Review of Stairway Falls and Stair Negotiation: Lessons Learned and Future Needs to Reduce Injury (2016) Gait Posture, 49, pp. 159-167. , [CrossRef] [PubMed]Beurskens, R., Bock, O., Age-Related Deficits of Dual-Task Walking: A Review (2012) Neural Plast, 2012, p. 131608. , [CrossRef] [PubMed]Raz, N., Lindenberger, U., Rodrigue, K.M., Kennedy, K.M., Head, D., Williamson, A., Dahle, C., Acker, J.D., Regional Brain Changes in Aging Healthy Adults: General Trends, Individual Differences and Modifiers (2005) Cereb. Cortex, 15, pp. 1676-1689. , [CrossRef] [PubMed]Li, K.Z.H., Bherer, L., Mirelman, A., Maidan, I., Hausdorff, J.M., Cognitive Involvement in Balance, Gait and Dual-Tasking in Aging: A Focused Review From a Neuroscience of Aging Perspective (2018) Front. Neurol, 9, p. 913. , [CrossRef] [PubMed]Yogev, G., Hausdorff, J.M., Giladi, N., The Role of Executive Function and Attention in Gait (2008) Mov. Disord. Off. J. Mov. Disord. Soc, 23, pp. 329-472. , [CrossRef]Hausdorff, J.M., Schweiger, A., Herman, T., Yogev-Seligmann, G., Giladi, N., Dual Task Decrements in Gait among Healthy Older Adults: Contributing Factors (2008) J. Gerontol. A. Biol. Sci. Med. Sci, 63, pp. 1335-1343. , [CrossRef] [PubMed]Woollacott, M., Shumway-Cook, A., Attention and the Control of Posture and Gait: A Review of an Emerging Area of Research (2002) Gait Posture, 16, pp. 1-14. , [CrossRef]Madehkhaksar, F., Egges, A., Effect of Dual Task Type on Gait and Dynamic Stability during Stair Negotiation at Different Inclinations (2016) Gait Posture, 43, pp. 114-119. , [CrossRef]Tiedemann, A.C., Sherrington, C., Lord, S.R., Physical and Psychological Factors Associated With Stair Negotiation Performance in Older People (2007) J. Gerontol. A. Biol. Sci. Med. Sci, 62, pp. 1259-1265. , [CrossRef]Lee, H.-J., Chou, L.-S., Balance Control during Stair Negotiation in Older Adults (2007) J. Biomech, 40, pp. 2530-2536. , [CrossRef]Miyasike-daSilva, V., Allard, F., McIlroy, W.E., Where Do We Look When We Walk on Stairs? Gaze Behaviour on Stairs, Transitions, and Handrails (2011) Exp. 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An FNIRS Study (2008) NeuroImage, 39, pp. 600-607. , [CrossRef] [PubMed]Koenraadt, K.L.M., Roelofsen, E.G.J., Duysens, J., Keijsers, N.L.W., Cortical Control of Normal Gait and Precision Stepping: An FNIRS Study (2014) NeuroImage, 85, pp. 415-422. , [CrossRef] [PubMed]Brain SciencesCognitive agingCognitive functionExecutive functionFunctional near-infrared spectroscopy (fNIRS)GaitNeuroimagingOlder adultPrefrontal cortex (PFC)Stair climbingagedarticlecognitive agingcontrolled studyexecutive functionfemalefunctional near-infrared spectroscopyhemodynamicshumanhuman experimentmaleneuroimagingprefrontal cortexreaction timestair climbingwalking speedPrefrontal cortex involvement during dual-task stair climbing in healthy older adults: An fNIRS studyArticleinfo:eu-repo/semantics/articlehttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_2df8fbb1Salzman, T., School of Human Kinetics, Faculty of Health Science, University of Ottawa, Ottawa, ON K1N 7K4, CanadaAboualmagd, A., Interdisciplinary School of Health Sciences, Faculty of Health Science, University of Ottawa, Ottawa, ON K1N 7K4, CanadaBadawi, H., Multimedia Communications Research Laboratory (MCRLab), School of Electrical Engineering and Computer Science, University of Ottawa, Ottawa, ON K1N 7K4, CanadaTobón-Vallejo, D., Electronics and Telecommunications Engineering Department, Universidad de Medellín, Medellín, 050030, ColombiaKim, H., School of Human Kinetics, Faculty of Health Science, University of Ottawa, Ottawa, ON K1N 7K4, CanadaDahroug, L., Interdisciplinary School of Health Sciences, Faculty of Health Science, University of Ottawa, Ottawa, ON K1N 7K4, CanadaLaamarti, F., Multimedia Communications Research Laboratory (MCRLab), School of Electrical Engineering and Computer Science, University of Ottawa, Ottawa, ON K1N 7K4, CanadaEl Saddik, A., Multimedia Communications Research Laboratory (MCRLab), School of Electrical Engineering and Computer Science, University of Ottawa, Ottawa, ON K1N 7K4, CanadaFraser, S., Interdisciplinary School of Health Sciences, Faculty of Health Science, University of Ottawa, Ottawa, ON K1N 7K4, Canadahttp://purl.org/coar/access_right/c_16ecSalzman T.Aboualmagd A.Badawi H.Tobón-Vallejo D.Kim H.Dahroug L.Laamarti F.El Saddik A.Fraser S.11407/5898oai:repository.udem.edu.co:11407/58982021-02-05 09:57:39.156Repositorio Institucional Universidad de Medellinrepositorio@udem.edu.co

Prefrontal cortex involvement during dual-task stair climbing in healthy older adults: An fNIRS study

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