Hemodynamic and behavioral changes in older adults during cognitively demanding dual tasks
Introduction: Executive functions play a fundamental role in walking by integrating information from cognitive-motor pathways. Subtle changes in brain and behavior may help identify older adults who are more susceptible to executive function deficits with advancing age due to prefrontal cortex deter...
- Autores:
- Tipo de recurso:
- Fecha de publicación:
- 2021
- Institución:
- Universidad de Medellín
- Repositorio:
- Repositorio UDEM
- Idioma:
- eng
- OAI Identifier:
- oai:repository.udem.edu.co:11407/5886
- Acceso en línea:
- http://hdl.handle.net/11407/5886
- Palabra clave:
- Aging
Cognitive science
dual-task walking
executive demands
fNIRS
Gait
Near Infra-red spectroscopy
Task Performance and Analysis
- Rights
- License
- http://purl.org/coar/access_right/c_16ec
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Hemodynamic and behavioral changes in older adults during cognitively demanding dual tasks |
| title |
Hemodynamic and behavioral changes in older adults during cognitively demanding dual tasks |
| spellingShingle |
Hemodynamic and behavioral changes in older adults during cognitively demanding dual tasks Aging Cognitive science dual-task walking executive demands fNIRS Gait Near Infra-red spectroscopy Task Performance and Analysis |
| title_short |
Hemodynamic and behavioral changes in older adults during cognitively demanding dual tasks |
| title_full |
Hemodynamic and behavioral changes in older adults during cognitively demanding dual tasks |
| title_fullStr |
Hemodynamic and behavioral changes in older adults during cognitively demanding dual tasks |
| title_full_unstemmed |
Hemodynamic and behavioral changes in older adults during cognitively demanding dual tasks |
| title_sort |
Hemodynamic and behavioral changes in older adults during cognitively demanding dual tasks |
| dc.subject.spa.fl_str_mv |
Aging Cognitive science dual-task walking executive demands fNIRS Gait Near Infra-red spectroscopy Task Performance and Analysis |
| topic |
Aging Cognitive science dual-task walking executive demands fNIRS Gait Near Infra-red spectroscopy Task Performance and Analysis |
| description |
Introduction: Executive functions play a fundamental role in walking by integrating information from cognitive-motor pathways. Subtle changes in brain and behavior may help identify older adults who are more susceptible to executive function deficits with advancing age due to prefrontal cortex deterioration. This study aims to examine how older adults mitigate executive demands while walking during cognitively demanding tasks. Methods: Twenty healthy older adults (M = 71.8 years, SD = 6.4) performed simple reaction time (SRT), go/no-go (GNG), n-back (NBK), and double number sequence (DNS) cognitive tasks of increasing difficulty while walking (i.e., dual task). Functional near infra-red spectroscopy (fNIRS) was used to measure the hemodynamic response (i.e., oxy- [HbO2] and deoxyhemoglobin [HbR]) changes in the prefrontal cortex (PFC) during dual and single tasks (i.e., walking alone). In addition, performance was measured using gait speed (m/s), response time (s), and accuracy (% correct). Results: Using repeated measures ANOVAs, neural findings demonstrated a main effect of task such that ∆HbO2 (p =.047) and ∆HbR (p =.040) decreased between single and dual tasks. An interaction between task and cognitive difficulty (p =.014) revealed that gait speed decreased in the DNS between single and dual tasks. A main effect of task in response time indicated that the SRT response time was faster than all other difficulty levels (p <.001). Accuracy performance declined between single and dual tasks (p =.028) and across difficulty levels (p <.001) but was not significantly different between the NBK and DNS. Conclusion: Findings suggest that a healthy older adult sample might mitigate executive demands using an automatic locomotor control strategy such that shifting conscious attention away from walking during the dual tasks resulted in decreased ∆HbO2 and ∆HbR. However, decreased prefrontal activation was inefficient at maintaining response time and accuracy performance and may be differently affected by increasing cognitive demands. © 2021 The Authors. Brain and Behavior published by Wiley Periodicals LLC |
| publishDate |
2021 |
| dc.date.accessioned.none.fl_str_mv |
2021-02-05T14:57:32Z |
| dc.date.available.none.fl_str_mv |
2021-02-05T14:57:32Z |
| dc.date.none.fl_str_mv |
2021 |
| dc.type.eng.fl_str_mv |
Article |
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http://purl.org/coar/version/c_970fb48d4fbd8a85 |
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http://purl.org/coar/resource_type/c_6501 http://purl.org/coar/resource_type/c_2df8fbb1 |
| dc.type.driver.none.fl_str_mv |
info:eu-repo/semantics/article |
| dc.identifier.issn.none.fl_str_mv |
21623279 |
| dc.identifier.uri.none.fl_str_mv |
http://hdl.handle.net/11407/5886 |
| dc.identifier.doi.none.fl_str_mv |
10.1002/brb3.2021 |
| identifier_str_mv |
21623279 10.1002/brb3.2021 |
| url |
http://hdl.handle.net/11407/5886 |
| dc.language.iso.none.fl_str_mv |
eng |
| language |
eng |
| dc.relation.isversionof.none.fl_str_mv |
https://www.scopus.com/inward/record.uri?eid=2-s2.0-85099016547&doi=10.1002%2fbrb3.2021&partnerID=40&md5=7f41cc0f78859abd960ebdb95849a1a3 |
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Al-Yahya, E., Dawes, H., Smith, L., Dennis, A., Howells, K., Cockburn, J., Cognitive motor interference while walking: A systematic review and meta-analysis (2011) Neuroscience & Biobehavioral Reviews, 35 (3), pp. 715-728. , https://doi.org/10.1016/j.neubiorev.2010.08.008 Al-Yahya, E., Johansen-Berg, H., Kischka, U., Zarei, M., Cockburn, J., Dawes, H., Prefrontal cortex activation while walking under dual-task conditions in stroke: A multimodal imaging study (2016) Neurorehabilitation and Neural Repair, 30 (6), pp. 591-599. , https://doi.org/10.1177/1545968315613864 Baddeley, A., (1986) Working memory, , Oxford University Press Beck, E., Intzandt, B., Almeida, Q.J., Can dual task walking improve in Parkinson’s disease after external focus of attention exercise? 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(2019) Photonics, 6 (3). , https://doi.org/10.3390/photonics6030087 Reuter-Lorenz, P., Park, D., How does it STAC up? 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Age and task associated findings (2009) Brain Research, 1253, pp. 92-99. , https://doi.org/10.1016/j.brainres.2008.11.067 St-Amant, G., Rahman, T., Polskaia, N., Fraser, S., Lajoie, Y., Unveilling the cerebral and sensory contributions to automatic postural control during dual-task standing (2020) Human Movement Science, 70. , https://doi.org/10.1016/j.humov.2020.102587 Strauss, P., Sherman, N., Spreen, O., (2006) A compendium of neuropsychological tests: Administration, norms, and commentary, , Oxford University Press Verghese, J., Wang, C., Ayers, E., Izzetoglu, M., Holtzer, R., Brain activation in high-functioning older adults and falls: Prospective cohort study (2017) Neurology, 88 (2), pp. 191-197. , https://doi.org/10.1212/WNL.0000000000003421 Vermeij, A., van Beek, A., Olde Rikkert, M., Claassen, J., Kessels, R., Effects of aging on cerebral oxygenation during working-memory performance: A functional near-infrared spectroscopy study (2012) PLoS One, 7 (9). , https://doi.org/10.1371/journal.pone.0046210 Wechsler, D., (1981) Wechsler adult intelligence scale-revised (WAIS-R), , Psychological Corporation Woollacott, M., Shumway-Cook, A., Attention and the control of posture and gait: A review of an emerging area of research (2002) Gait & Posture, 16 (1), pp. 1-14. , https://doi.org/10.1016/S0966-6362(01)00156-4 Wu, T., Kansaku, K., Hallett, M., How Self-Initiated Memorized Movements Become Automatic: A Functional MRI Study (2004) Journal of Neurophysiology, 91 (4), pp. 1690-1698. , https://doi.org/10.1152/jn.01052.2003 Wulf, G., Shea, C., Park, J., Attention and motor performance: Preferences for and advantages of an external focus (2001) Research Quarterly for Exercise and Sport, 72 (4), pp. 335-344. , https://doi.org/10.1080/02701367.2001.10608970 Yesavage, J., Sheikh, A., Geriatric depression scale (GDS) (1986) Clinical Gerontologist, 5 (1-2), pp. 165-173. , https://doi.org/10.1300/J018v05n01_09 Yogev, G., Hausdorff, J., Giladi, N., The role of executive function and attention in gait (2008) Movement Disorders: Official Journal of the Movement Disorder Society, 23 (3), pp. 329-472. , https://doi.org/10.1002/mds.21720 Yogev-Seligmann, G., Hausdorff, J., Giladi, N., Do we always prioritize balance when walking? Towards an integrated model of task prioritization (2012) Movement Disorders, 27 (6), pp. 765-770. , https://doi.org/10.1002/mds.24963 |
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http://purl.org/coar/access_right/c_16ec |
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http://purl.org/coar/access_right/c_16ec |
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John Wiley and Sons Ltd |
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Ingeniería de Telecomunicaciones |
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Facultad de Ingenierías |
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John Wiley and Sons Ltd |
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Brain and Behavior |
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Universidad de Medellín |
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Repositorio Institucional Universidad de Medellin |
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repositorio@udem.edu.co |
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1814159176719400960 |
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20212021-02-05T14:57:32Z2021-02-05T14:57:32Z21623279http://hdl.handle.net/11407/588610.1002/brb3.2021Introduction: Executive functions play a fundamental role in walking by integrating information from cognitive-motor pathways. Subtle changes in brain and behavior may help identify older adults who are more susceptible to executive function deficits with advancing age due to prefrontal cortex deterioration. This study aims to examine how older adults mitigate executive demands while walking during cognitively demanding tasks. Methods: Twenty healthy older adults (M = 71.8 years, SD = 6.4) performed simple reaction time (SRT), go/no-go (GNG), n-back (NBK), and double number sequence (DNS) cognitive tasks of increasing difficulty while walking (i.e., dual task). Functional near infra-red spectroscopy (fNIRS) was used to measure the hemodynamic response (i.e., oxy- [HbO2] and deoxyhemoglobin [HbR]) changes in the prefrontal cortex (PFC) during dual and single tasks (i.e., walking alone). In addition, performance was measured using gait speed (m/s), response time (s), and accuracy (% correct). Results: Using repeated measures ANOVAs, neural findings demonstrated a main effect of task such that ∆HbO2 (p =.047) and ∆HbR (p =.040) decreased between single and dual tasks. An interaction between task and cognitive difficulty (p =.014) revealed that gait speed decreased in the DNS between single and dual tasks. A main effect of task in response time indicated that the SRT response time was faster than all other difficulty levels (p <.001). Accuracy performance declined between single and dual tasks (p =.028) and across difficulty levels (p <.001) but was not significantly different between the NBK and DNS. Conclusion: Findings suggest that a healthy older adult sample might mitigate executive demands using an automatic locomotor control strategy such that shifting conscious attention away from walking during the dual tasks resulted in decreased ∆HbO2 and ∆HbR. However, decreased prefrontal activation was inefficient at maintaining response time and accuracy performance and may be differently affected by increasing cognitive demands. © 2021 The Authors. Brain and Behavior published by Wiley Periodicals LLCengJohn Wiley and Sons LtdIngeniería de TelecomunicacionesFacultad de Ingenieríashttps://www.scopus.com/inward/record.uri?eid=2-s2.0-85099016547&doi=10.1002%2fbrb3.2021&partnerID=40&md5=7f41cc0f78859abd960ebdb95849a1a3Al-Yahya, E., Dawes, H., Smith, L., Dennis, A., Howells, K., Cockburn, J., Cognitive motor interference while walking: A systematic review and meta-analysis (2011) Neuroscience & Biobehavioral Reviews, 35 (3), pp. 715-728. , https://doi.org/10.1016/j.neubiorev.2010.08.008Al-Yahya, E., Johansen-Berg, H., Kischka, U., Zarei, M., Cockburn, J., Dawes, H., Prefrontal cortex activation while walking under dual-task conditions in stroke: A multimodal imaging study (2016) Neurorehabilitation and Neural Repair, 30 (6), pp. 591-599. , https://doi.org/10.1177/1545968315613864Baddeley, A., (1986) Working memory, , Oxford University PressBeck, E., Intzandt, B., Almeida, Q.J., Can dual task walking improve in Parkinson’s disease after external focus of attention exercise? 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