Virus de la leucemia felina: un patógeno actual que requiere atención en Colombia

RESUMEN:  El virus de la leucemia felina (FeLV) es un gammaretrovirus que afecta a felinos domésticos de todo el mundo y esporádicamente a felinos salvajes. La forma más común  de contagio es la transmisión horizontal, siendo más frecuentes las infecciones por contacto con...

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diagnóstico
epidemiología
gammaretrovirus
PCR
diagnosis
epidemiology
gammaretrovirus
PCR
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dc.title.none.fl_str_mv Virus de la leucemia felina: un patógeno actual que requiere atención en Colombia
Feline Leukemia Virus: A current pathogen requiring attention in Colombia
title Virus de la leucemia felina: un patógeno actual que requiere atención en Colombia
spellingShingle Virus de la leucemia felina: un patógeno actual que requiere atención en Colombia
diagnóstico
epidemiología
gammaretrovirus
PCR
diagnosis
epidemiology
gammaretrovirus
PCR
title_short Virus de la leucemia felina: un patógeno actual que requiere atención en Colombia
title_full Virus de la leucemia felina: un patógeno actual que requiere atención en Colombia
title_fullStr Virus de la leucemia felina: un patógeno actual que requiere atención en Colombia
title_full_unstemmed Virus de la leucemia felina: un patógeno actual que requiere atención en Colombia
title_sort Virus de la leucemia felina: un patógeno actual que requiere atención en Colombia
dc.subject.none.fl_str_mv diagnóstico
epidemiología
gammaretrovirus
PCR
diagnosis
epidemiology
gammaretrovirus
PCR
topic diagnóstico
epidemiología
gammaretrovirus
PCR
diagnosis
epidemiology
gammaretrovirus
PCR
description RESUMEN:  El virus de la leucemia felina (FeLV) es un gammaretrovirus que afecta a felinos domésticos de todo el mundo y esporádicamente a felinos salvajes. La forma más común  de contagio es la transmisión horizontal, siendo más frecuentes las infecciones por contacto con saliva y por consumo de leche de una gata infectada. Recientemente se han logrado grandes avances en la comprensión y la clasificación de los gatos infectados por el FeLV, reconociéndose en la actualidad cuatro diferentes tipos de infección. Clínicamente, la enfermedad se caracteriza por el desarrollo de enfermedades neoplásicas, no neoplásicas y enfermedades reproductivas; su diagnóstico definitivo se  puede realizar por medio de pruebas como ELISA, inmunocromatografía y PCR. El tratamiento en los animales clínicamente enfermos se basa principalmente en el  manejo sintomático, aunque se han logrado progresos en el uso de medicamentos antivirales. Dada su fácil transmisión, es de suma importancia la prevención del contagio en gatos sanos a través del aislamiento de animales enfermos y la vacunación. En Colombia se han realizado algunos estudios exploratorios que han demostrado prevalencias superiores al 20% en gatos domésticos; sin embargo, a la fecha no se han realizado estudios moleculares que permitan la caracterización del FeLV circulante en el país ni se ha logrado la implementación de medidas más enfocadas de prevención y control.
publishDate 2022
dc.date.none.fl_str_mv 2022-03-17T01:04:00Z
2022-03-17T01:04:00Z
2022-03-17
2025-10-08T21:57:59Z
2025-10-08T21:57:59Z
dc.type.none.fl_str_mv Artículo de revista
http://purl.org/coar/resource_type/c_6501
http://purl.org/coar/resource_type/c_dcae04bc
Text
info:eu-repo/semantics/article
Journal article
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info:eu-repo/semantics/publishedVersion
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https://revistasojs.ucaldas.edu.co/index.php/vetzootec/article/view/4387
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Revista Veterinaria y Zootecnia (On Line)
ABCD - European Advisory Board on Cat Diseases. Infección por el virus de la leucemia felina. Ficha técnica. p.3, 2009.
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Arjona, A.; Barquero, N.; Doménech, A. et al. Evaluation of a novel nested PCR for the routine diagnosis of feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV). Journal of Feline Medicine and Surgery, v.9, n.1, p.14-22, 2007.
Belgard, S.; Truyen, U.; Thibault, J.C. et al. Relevance of feline calicivirus, feline immunodeficiency virus, feline leukemia virus, feline herpesvirus and Bartonella henselae in cats with chronic gingivostomatitis. Berliner und Munchener Tierarztliche Wochenschrift, v.123, n.9-10, p.369-376, 2010.
Benavides, H. Presente y futuro de la leucemia viral felina y del virus de inmunodeficiencia adquirida felina en Santafé de Bogotá 1996-1999. Seminario en medicina felina, Bogotá. Memorias. p.114-128, 2000.
Bolin, L.L.; Levy, L.S. Viral determinants of FeLV infection and pathogenesis: lessons learned from analysis of a natural cohort. Viruses, v.3, n.9, p.1681-98, 2011.
Cattori, V.; Hofmann-Lehmann R. Absolute quantitation of feline leukemia virus proviral DNA and viral RNA loads by TaqMan real-time PCR and RT-PCR. Methods Mol Biol, v.429, p.73-87, 2008.
Cattori, V.; Pepin, A.C.; Tandon, R. et al. Real-time PCR investigation of feline leukemia virus proviral and viral RNA loads in leukocyte subsets. Veterinary Immunology and Immunopathology, v.123, n.1-2, p.124-128, 2008.
Cattori, V.; Tandon, R.; Riond, B. et al. The kinetics of feline leukaemia virus shedding in experimentally infected cats are associated with infection outcome. Veterinary Microbiology, v.133, n.3, p.292-6, 2009.
Cattori, V.; Weibel, B.; Lutz, H. Inhibition of Feline leukemia virus replication by the integrase inhibitor Raltegravir. Veterinary Microbiology, v.152, n.1-2, p.165-8, 2011.
Coelho, F.M.; Bomfim, M.R.; De Andrade Caxito, F. et al. Naturally occurring feline leukemia virus subgroup A and B infections in urban domestic cats. Journal of General Virology, v.89, n.11, p.2799-2805, 2008.
De Mari, K.; Maynard, L.; Sanquer, A. et al. Therapeutic effects of recombinant feline interferon-omega on feline leukemia virus (FeLV) infected and FeLV/feline immunodeficiency virus (FIV)-coinfected symptomatic cats. Journal of Veterinary Internal Medicine, v.18, n.4, p.477-82, 2004.
Doménech, A.; Miró, G.; Collado, V.M. et al. Use of recombinant interferon omega in feline retrovirosis: from theory to practice. Veterinary Immunology and Immunopathology, v.143, n.3-4, p.301-6, 2011.
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Núm. 2 , Año 2013 : Julio - Diciembre
https://revistasojs.ucaldas.edu.co/index.php/vetzootec/article/download/4387/4029
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publisher.none.fl_str_mv Universidad de Caldas
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spelling Virus de la leucemia felina: un patógeno actual que requiere atención en ColombiaFeline Leukemia Virus: A current pathogen requiring attention in ColombiadiagnósticoepidemiologíagammaretrovirusPCRdiagnosisepidemiologygammaretrovirusPCRRESUMEN:&amp;nbsp; El virus de la leucemia felina (FeLV) es un gammaretrovirus que afecta a felinos domésticos de todo el mundo y esporádicamente a felinos salvajes. La forma más común&amp;nbsp; de contagio es la transmisión horizontal, siendo más frecuentes las infecciones por contacto con saliva y por consumo de leche de una gata infectada. Recientemente se han logrado grandes avances en la comprensión y la clasificación de los gatos infectados por el FeLV, reconociéndose en la actualidad cuatro diferentes tipos de infección. Clínicamente, la enfermedad se caracteriza por el desarrollo de enfermedades neoplásicas, no neoplásicas y enfermedades reproductivas; su diagnóstico definitivo se&amp;nbsp; puede realizar por medio de pruebas como ELISA, inmunocromatografía y PCR. El tratamiento en los animales clínicamente enfermos se basa principalmente en el&amp;nbsp; manejo sintomático, aunque se han logrado progresos en el uso de medicamentos antivirales. Dada su fácil transmisión, es de suma importancia la prevención del contagio en gatos sanos a través del aislamiento de animales enfermos y la vacunación. En Colombia se han realizado algunos estudios exploratorios que han demostrado prevalencias superiores al 20% en gatos domésticos; sin embargo, a la fecha no se han realizado estudios moleculares que permitan la caracterización del FeLV circulante en el país ni se ha logrado la implementación de medidas más enfocadas de prevención y control.The feline leukemia virus (FeLV) is a gammaretrovirus that affectsdomestic felines all over the world and, sporadically wild felines. The most common form of transmission&amp;nbsp; is the horizontal infection being more frequent the contact with saliva and milk consumption from a FeLV infected cat. Recently great advances have been achieved in the understanding and classification of FeLV infectedcatsbeing possible today to recognize four different types of infection. Clinically, the disease is&amp;nbsp; characterized by the development of neoplastic, non-neoplastic and reproductive diseases.Thier definitive diagnosis can be performed by ELISA, PCR and immunocromatography. The treatment in clinically ill animals is mainly based on symptomatic management, although progress has been made in the use of antiretroviral therapy. Given its easy transmission,it is very important the prevention of infection in healthy cats through isolation of sick animals and vaccination. In Colombia some exploratory studies have been carried out which have shown that prevalence ishigher than 20% in domestic cats; however to date, there have been neithermolecular studies which allow characterization of the FeLVdevelopingin the country nor implementation of measures more focused on prevention and control have been fulfilled.Universidad de Caldas2022-03-17T01:04:00Z2025-10-08T21:57:59Z2022-03-17T01:04:00Z2025-10-08T21:57:59Z2022-03-17Artículo de revistahttp://purl.org/coar/resource_type/c_6501http://purl.org/coar/resource_type/c_dcae04bcTextinfo:eu-repo/semantics/articleJournal articlehttp://purl.org/redcol/resource_type/ARTREVinfo:eu-repo/semantics/publishedVersionhttp://purl.org/coar/version/c_970fb48d4fbd8a85http://purl.org/coar/resource_type/c_2df8fbb1application/pdfhttps://repositorio.ucaldas.edu.co/handle/ucaldas/255222011-5415https://revistasojs.ucaldas.edu.co/index.php/vetzootec/article/view/4387https://revistasojs.ucaldas.edu.co/index.php/vetzootec/article/view/4387spa13821177Revista Veterinaria y Zootecnia (On Line)ABCD - European Advisory Board on Cat Diseases. Infección por el virus de la leucemia felina. Ficha técnica. p.3, 2009.Anai, Y.; Ochi, H.; Watanabe, S. et al. Infectious endogenous retroviruses in cats and emergence of recombinant viruses. Journal of Virology, v.86, n.16, p.8634-844, 2012.Anderson, M.M.; Lauring, A.S.; Burns, C.C. et al. Identification of a cellular cofactor required for infection by feline leukemia virus. Science, v.287, p.1828-1830, 2000.Arjona, A.; Barquero, N.; Doménech, A. et al. Evaluation of a novel nested PCR for the routine diagnosis of feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV). Journal of Feline Medicine and Surgery, v.9, n.1, p.14-22, 2007.Belgard, S.; Truyen, U.; Thibault, J.C. et al. Relevance of feline calicivirus, feline immunodeficiency virus, feline leukemia virus, feline herpesvirus and Bartonella henselae in cats with chronic gingivostomatitis. Berliner und Munchener Tierarztliche Wochenschrift, v.123, n.9-10, p.369-376, 2010.Benavides, H. 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Journal of Small Animal Practice, v.51, n.6, p.1-32, 2010.Núm. 2 , Año 2013 : Julio - Diciembrehttps://revistasojs.ucaldas.edu.co/index.php/vetzootec/article/download/4387/4029https://creativecommons.org/licenses/by-nc-sa/4.0/info:eu-repo/semantics/openAccesshttp://purl.org/coar/access_right/c_abf2Calle Restrepo, Juan FelipeFernández González, LauraMorales Zapata, Laura MarcelaRuiz Sáenz, Juliánoai:repositorio.ucaldas.edu.co:ucaldas/255222025-10-08T21:57:59Z